All Relations between microtubule-associated protein tau and temporal lobe

Publication Sentence Publish Date Extraction Date Species
Anika Wuestefeld, Hannah Baumeister, Jenna N Adams, Robin de Flores, Carl J Hodgetts, Negar Mazloum-Farzaghi, Rosanna K Olsen, Vyash Puliyadi, Tammy T Tran, Arnold Bakker, Kelsey L Canada, Marshall A Dalton, Ana M Daugherty, Renaud La Joie, Lei Wang, Madigan L Bedard, Esther Buendia, Eunice Chung, Amanda Denning, María Del Mar Arroyo-Jiménez, Emilio Artacho-Pérula, David J Irwin, Ranjit Ittyerah, Edward B Lee, Sydney Lim, María Del Pilar Marcos-Rabal, Maria Mercedes Iñiguez de Onzoño Martin, Monica Munoz Lopez, Carlos de la Rosa Prieto, Theresa Schuck, Winifred Trotman, Alicia Vela, Paul Yushkevich, Katrin Amunts, Jean C Augustinack, Song-Lin Ding, Ricardo Insausti, Olga Kedo, David Berron, Laura E M Wiss. Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories. Hippocampus. 2024-02-28. PMID:38415962. the medial temporal lobe (mtl) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as alzheimer's disease neurofibrillary tau tangles. 2024-02-28 2024-03-01 human
Abigail Alexander, Victor E Alvarez, Bertrand R Huber, Michael L Alosco, Jesse Mez, Yorghos Tripodis, Raymond Nicks, Douglas I Katz, Brigid Dwyer, Daniel H Daneshvar, Brett Martin, Joseph Palmisano, Lee E Goldstein, John F Crary, Christopher Nowinski, Robert C Cantu, Neil W Kowall, Robert A Stern, Ivana Delalle, Ann C McKee, Thor D Stei. Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE. Acta neuropathologica. vol 147. issue 1. 2024-02-26. PMID:38407651. cross-sectional studies suggest that tau inclusions follow a stereotyped pattern that begins in the neocortex in low stage disease, followed by involvement of the medial temporal lobe and subcortical regions with significant neocortical burden in high stage cte. 2024-02-26 2024-02-28 human
Abigail Alexander, Victor E Alvarez, Bertrand R Huber, Michael L Alosco, Jesse Mez, Yorghos Tripodis, Raymond Nicks, Douglas I Katz, Brigid Dwyer, Daniel H Daneshvar, Brett Martin, Joseph Palmisano, Lee E Goldstein, John F Crary, Christopher Nowinski, Robert C Cantu, Neil W Kowall, Robert A Stern, Ivana Delalle, Ann C McKee, Thor D Stei. Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE. Acta neuropathologica. vol 147. issue 1. 2024-02-26. PMID:38407651. cscte had less overall tau pathology severity, but a proportional increase of disease burden in medial temporal lobe and brainstem regions compared to the neocortex (p's < 0.001). 2024-02-26 2024-02-28 human
Lydia Jiang, Jessica Robin, Nathanael Shing, Negar Mazloum-Farzaghi, Natalia Ladyka-Wojcik, Niroja Balakumar, Nicole D Anderson, Jennifer D Ryan, Morgan D Barense, Rosanna K Olse. Impaired perceptual discrimination of complex objects in older adults at risk for dementia. Hippocampus. 2024-01-08. PMID:38189156. tau pathology accumulates in the perirhinal cortex (prc) of the medial temporal lobe (mtl) during the earliest stages of the alzheimer's disease (ad), appearing decades before clinical diagnosis. 2024-01-08 2024-01-10 Not clear
Nisha Rani, Kylie H Alm, Caitlin A Corona-Long, Caroline L Speck, Anja Soldan, Corinne Pettigrew, Yuxin Zhu, Marilyn Albert, Arnold Bakke. Tau PET burden in Brodmann areas 35 and 36 is associated with individual differences in cognition in non-demented older adults. Frontiers in aging neuroscience. vol 15. 2024-01-01. PMID:38161595. the accumulation of neurofibrillary tau tangles, a neuropathological hallmark of alzheimer's disease (ad), occurs in medial temporal lobe (mtl) regions early in the disease process, with some of the earliest deposits localized to subregions of the entorhinal cortex. 2024-01-01 2024-01-05 Not clear
Kaitlyn M Dybing, Cecelia J Vetter, Desarae A Dempsey, Soumilee Chaudhuri, Andrew J Saykin, Shannon L Risache. Traumatic brain injury and Alzheimer's Disease biomarkers: A systematic review of findings from amyloid and tau positron emission tomography (PET). medRxiv : the preprint server for health sciences. 2023-12-11. PMID:38077068. evidence for increased tau was strongest in the medial temporal lobe, entorhinal cortex, precuneus, and frontal, temporal, parietal, and occipital lobes. 2023-12-11 2023-12-17 human
Lingchao Li, Bin Ji, Min Zhao, Lin Bai, Bin Che. Nonfluent Variant Primary Progressive Aphasia on FDG, 11C-PIB, and 18F-APN-1607 PET Imaging. Clinical nuclear medicine. 2023-09-27. PMID:37756439. the 11c-pib pet showed no amyloid accumulation; the 18f-fdg pet showed hypometabolism in the bilateral frontal lobe, temporal lobe, and midbrain; and the 18f-apn-1607 pet showed tau accumulation in the brainstem, basal ganglia, and left inferior frontal gyrus. 2023-09-27 2023-10-07 Not clear
Tiffany E Chow, Christina R Veziris, Nidhi Mundada, Alexis I Martinez-Arroyo, Joel H Kramer, Bruce L Miller, Howard J Rosen, Maria Luisa Gorno-Tempini, Katherine P Rankin, William W Seeley, Gil D Rabinovici, Renaud La Joie, Virginia E Stur. Medial Temporal Lobe Tau Aggregation Relates to Divergent Cognitive and Emotional Empathy Abilities in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2023-09-24. PMID:37742643. medial temporal lobe tau aggregation relates to divergent cognitive and emotional empathy abilities in alzheimer's disease. 2023-09-24 2023-10-07 Not clear
Meaghan Morris, Gabrielle I Coste, Javier Redding-Ochoa, Haidan Guo, Austin R Graves, Juan C Troncoso, Richard L Hugani. Hippocampal synaptic alterations associated with tau pathology in primary age-related tauopathy. Journal of neuropathology and experimental neurology. 2023-08-23. PMID:37595576. primary age-related tauopathy (part) is characterized by aggregation of tau in the mesial temporal lobe in older individuals. 2023-08-23 2023-09-07 Not clear
Alejandro Costoya-Sánchez, Alexis Moscoso, Jesús Silva-Rodríguez, Michael J Pontecorvo, Michael D Devous, Pablo Aguiar, Michael Schöll, Michel J Groth. Increased Medial Temporal Tau Positron Emission Tomography Uptake in the Absence of Amyloid-β Positivity. JAMA neurology. 2023-08-14. PMID:37578787. an increased tau positron emission tomography (pet) signal in the medial temporal lobe (mtl) has been observed in older individuals in the absence of amyloid-β (aβ) pathology. 2023-08-14 2023-08-16 Not clear
Dario Bachmann, Andreas Buchmann, Sandro Studer, Antje Saake, Katrin Rauen, Isabelle Zuber, Esmeralda Gruber, Roger M Nitsch, Christoph Hock, Anton Gietl, Valerie Treye. Age-, sex-, and pathology-related variability in brain structure and cognition. Translational psychiatry. vol 13. issue 1. 2023-08-13. PMID:37574523. both age and amyloid-pet could be associated with medial temporal lobe tau, depending on whether we used a continuous or a dichotomous amyloid variable. 2023-08-13 2023-08-16 human
Dario Bachmann, Andreas Buchmann, Sandro Studer, Antje Saake, Katrin Rauen, Isabelle Zuber, Esmeralda Gruber, Roger M Nitsch, Christoph Hock, Anton Gietl, Valerie Treye. Age-, sex-, and pathology-related variability in brain structure and cognition. Translational psychiatry. vol 13. issue 1. 2023-08-13. PMID:37574523. tau burden in entorhinal cortex was related to worse episodic memory in individuals with increased amyloid burden (centiloid >12) independently of medial temporal lobe atrophy. 2023-08-13 2023-08-16 human
Kohji Mori, Kazue Shigenobu, Goichi Beck, Ryota Uozumi, Yuto Satake, Maki Suzuki, Shizuko Kondo, Shiho Gotoh, Yuki Yonenobu, Makiko Kawai, Yuki Suzuki, Yuko Saito, Eiichi Morii, Masato Hasegawa, Hideki Mochizuki, Shigeo Murayama, Manabu Iked. A heterozygous splicing variant IVS9-7A > T in intron 9 of the MAPT gene in a patient with right-temporal variant frontotemporal dementia with atypical 4 repeat tauopathy. Acta neuropathologica communications. vol 11. issue 1. 2023-08-10. PMID:37563653. postmortem neuropathological analysis revealed a predominant accumulation of 4 repeat tau, especially in the temporal lobe, amygdala, and substantia nigra, but lacked astrocytic plaques or tufted astrocytes. 2023-08-10 2023-08-16 Not clear
Shojiro Ichimata, Ivan Martinez-Valbuena, Seojin Lee, Jun Li, Ali M Karakani, Gabor G Kovac. Distinct Molecular Signatures of Amyloid-Beta and Tau in Alzheimer's Disease Associated with Down Syndrome. International journal of molecular sciences. vol 24. issue 14. 2023-07-29. PMID:37511361. we assessed aβ and tau deposition severity in the temporal lobe and cerebellum of ten ds and ten sad cases. 2023-07-29 2023-08-14 Not clear
Leon M Aksman, Neil P Oxtoby, Marzia A Scelsi, Peter A Wijeratne, Alexandra L Young, Isadora Lopes Alves, Lyduine E Collij, Jacob W Vogel, Frederik Barkhof, Daniel C Alexander, Andre Altman. A data-driven study of Alzheimer's disease related amyloid and tau pathology progression. Brain : a journal of neurology. 2023-07-11. PMID:37433038. this is because of the spatial discordance between amyloid-beta, which accumulates in the neocortex, and tau, which accumulates in the medial temporal lobe during aging. 2023-07-11 2023-08-14 Not clear
Leon M Aksman, Neil P Oxtoby, Marzia A Scelsi, Peter A Wijeratne, Alexandra L Young, Isadora Lopes Alves, Lyduine E Collij, Jacob W Vogel, Frederik Barkhof, Daniel C Alexander, Andre Altman. A data-driven study of Alzheimer's disease related amyloid and tau pathology progression. Brain : a journal of neurology. 2023-07-11. PMID:37433038. there is evidence that in some cases amyloid-beta-independent tau spreads beyond the medial temporal lobe where it may interact with neocortical amyloid-beta. 2023-07-11 2023-08-14 Not clear
Leon M Aksman, Neil P Oxtoby, Marzia A Scelsi, Peter A Wijeratne, Alexandra L Young, Isadora Lopes Alves, Lyduine E Collij, Jacob W Vogel, Frederik Barkhof, Daniel C Alexander, Andre Altman. A data-driven study of Alzheimer's disease related amyloid and tau pathology progression. Brain : a journal of neurology. 2023-07-11. PMID:37433038. in the amyloid-first subtype, extensive neocortical amyloid-beta precedes the spread of tau beyond the medial temporal lobe, while in the tau-first subtype mild tau accumulates in medial temporal and neocortical areas prior to interacting with amyloid-beta. 2023-07-11 2023-08-14 Not clear
Anika Wuestefeld, Hannah Baumeister, Jenna N Adams, Robin de Flores, Carl Hodgetts, Negar Mazloum-Farzaghi, Rosanna K Olsen, Vyash Puliyadi, Tammy T Tran, Arnold Bakker, Kelsey L Canada, Marshall A Dalton, Ana M Daugherty, Renaud La Joie, Lei Wang, Madigan Bedard, Esther Buendia, Amanda Denning, David J Irwin, Ranjit Ittyerah, Edward B Lee, Sydney Lim, Maria Mercedes Iñiguez de Onzoño Martin, Monica Munoz Lopez, Theresa Schuck, Winifred Trotman, Alicia Vela, Paul Yushkevich, Katrin Amunts, Jean C Augustinack, Song-Lin Ding, Ricardo Insausti, Olga Kedo, David Berron, Laura E M Wiss. Comparison of histological delineations of medial temporal lobe cortices by four independent neuroanatomy laboratories. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37292729. the medial temporal lobe (mtl) cortex, located adjacent to the hippocampus, is crucial for memory and prone to the accumulation of certain neuropathologies such as alzheimer's disease neurofibrillary tau tangles. 2023-06-09 2023-08-14 human
Deborah N Schoonhoven, Emma M Coomans, Ana P Millán, Anne M van Nifterick, Denise Visser, Rik Ossenkoppele, Hayel Tuncel, Wiesje M van der Flier, Sandeep S V Golla, Philip Scheltens, Arjan Hillebrand, Bart N M van Berckel, Cornelis J Stam, Alida A Gou. Tau protein spreads through functionally connected neurons in Alzheimer's disease: a combined MEG/PET study. Brain : a journal of neurology. 2023-06-06. PMID:37279597. tau propagation was modelled as an epidemic process (susceptible-infected model) on meg-based functional networks (in alpha (8-13hz) and beta (13-30hz) bands), a structural, or diffusion network, starting from the middle and inferior temporal lobe. 2023-06-06 2023-08-14 human
Anna Rennie, Urban Ekman, John Wallert, J-Sebastian Muehlboeck, Maria Eriksdotter, Lars-Olof Wahlund, Daniel Ferreira, Eric Westma. Comparing three neuropsychological subgrouping approaches in subjective and mild cognitive impairment from a naturalistic multicenter study. Neurobiology of aging. vol 129. 2023-06-03. PMID:37269645. biomarkers included cerebrospinal fluid measures of beta-amyloid-42 and phosphorylated tau, as well as visual ratings of medial temporal lobe atrophy and white matter hyperintensities on magnetic resonance imaging. 2023-06-03 2023-08-14 Not clear