| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Steven J Nieto, Colin N Haile, Cana B Quave, Mark J Harding, David A Nielsen, Richard A Meisch, Therese A Koste. Paternal alcohol exposure reduces acquisition of operant alcohol self-administration and affects Bdnf DNA methylation in male and female offspring. Addiction biology. 2021-08-07. PMID:34363290. |
dna methylation levels of the brain derived neurotrophic factor (bdnf) gene were measured in sperm, nucleus accumbens (nac) and medial prefrontal cortex (mpfc) in sires and in offspring. |
2021-08-07 |
2023-08-13 |
mouse |
| Mi Yang, Chang-Hao Luo, Ying-Qi Zhu, Yuan-Chu Liu, Ye-Juan An, Javed Iqbal, Zhe-Zhi Wang, Xin-Ming M. 7, 8-Dihydroxy-4-methylcoumarin reverses depression model-induced depression-like behaviors and alteration of dendritic spines in the mood circuits. Psychoneuroendocrinology. vol 119. 2021-07-21. PMID:32563935. |
the aim of this study was to investigate whether dhmc alleviates chronic unpredictable mild stress (cums)-induced depression-like behaviors and reverses cums-induced alterations in dendritic spines of principal neurons in brain areas of the emotional circuits including the hippocampus, medial prefrontal cortex (mpfc), nucleus accumbens (nac) and basolateral amygdala (bla) in male rats. |
2021-07-21 |
2023-08-13 |
rat |
| Mitra-Sadat Sadat-Shirazi, Haniyeh Soltani, Neda Nikpour, Masoud Haghshenas, Solmaz Khalifeh, Azarakhsh Mokri, Mohammad-Reza Zarrindas. Alteration of orexin-A and PKCα in the postmortem brain of pure-opioid and multi-drug abusers. Neuropeptides. vol 83. 2021-07-16. PMID:32741526. |
the medial prefrontal cortex (mpfc), lateral prefrontal cortex (lpfc), orbitofrontal cortex (ofc), nucleus accumbens (nac), and amygdala were dissected from fresh brain, frozen with liquid nitrogen and kept at -80 °c. |
2021-07-16 |
2023-08-13 |
Not clear |
| Andrew Chih Wei Huang, Ying Hao Yu, Alan Bo Han He, Chen Yin O. Interactions between prelimbic cortex and basolateral amygdala contribute to morphine-induced conditioned taste aversion in conditioning and extinction. Neurobiology of learning and memory. vol 172. 2021-07-14. PMID:32407964. |
the consequences of exciting or destroying the prelimbic cortex (prl) or the basolateral amygdala (bla) remain unclear, including the effects on morphine-induced conditioned taste aversion (cta) in the conditioning and extinction phases, plasma corticosterone (cort) levels, and c-fos/p-erk expressions in the subareas of the medial prefrontal cortex (i.e., prl, infralimbic cortex [il], cingulate cortex 1 [cg1]), basolateral amygdala (bla), central amygdala (cea), hippocampus (i.e., ca1, ca2, ca3, and dentate gyrus [dg]), nucleus accumbens (nac), lateral hypothalamus (lh), and piriform cortex (pc). |
2021-07-14 |
2023-08-13 |
Not clear |
| Gabriella Margetts-Smith, Anastasia I Macnaghten, Leonie S Brebner, Joseph J Ziminski, Meike C Sieburg, Jeffrey W Grimm, Hans S Crombag, Eisuke Koy. Acute, but not longer-term, exposure to environmental enrichment attenuates Pavlovian cue-evoked conditioned approach and Fos expression in the prefrontal cortex in mice. The European journal of neuroscience. vol 53. issue 8. 2021-06-29. PMID:33565633. |
we therefore measured the effects of acute/intermittent (1 day or 6 day of ee prior to test day) versus chronic (ee throughout conditioning lasting until test day) ee on the ability of a pavlovian sucrose cue to elicit sucrose seeking (conditioned approach) and fos expression in the medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), and nucleus accumbens (nac) in mice. |
2021-06-29 |
2023-08-13 |
mouse |
| Meriem Haddar, Kyosuke Uno, Katsunori Azuma, Shin-Ichi Muramatsu, Atsumi Nitt. Inhibitory effects of Shati/Nat8l overexpression in the medial prefrontal cortex on methamphetamine-induced conditioned place preference in mice. Addiction biology. vol 25. issue 3. 2021-06-24. PMID:30950164. |
meanwhile, dopamine (da) and glutamate dysregulations have been reported in the medial prefrontal cortex (mpfc) and nac after meth self-administration and during reinstatement. |
2021-06-24 |
2023-08-13 |
mouse |
| Di Liu, Qian-Qian Tang, Di Wang, Su-Pei Song, Xiao-Na Yang, Su-Wan Hu, Zhi-Yong Wang, Zheng Xu, He Liu, Jun-Xia Yang, Sarah E Montgomery, Hongxing Zhang, Ming-Hu Han, Hai-Lei Ding, Jun-Li Ca. Mesocortical BDNF signaling mediates antidepressive-like effects of lithium. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 9. 2021-06-23. PMID:32428928. |
here, we demonstrated that the ventral tegmental area (vta) dopamine (da) neurons that project to the medial prefrontal cortex (mpfc), but not to nucleus accumbens (nac), contributed to the antidepressive-like effects of lithium. |
2021-06-23 |
2023-08-13 |
mouse |
| Miguel Skirzewski, Marie E Cronin, Ricardo Murphy, Wambura Fobbs, Alexxai V Kravitz, Andres Buonann. ErbB4 Null Mice Display Altered Mesocorticolimbic and Nigrostriatal Dopamine Levels as well as Deficits in Cognitive and Motivational Behaviors. eNeuro. vol 7. issue 3. 2021-06-18. PMID:32354758. |
here, we report that extracellular steady-state levels of da are reduced in the medial prefrontal cortex (mpfc; -65%), hippocampus (-53%) and nucleus accumbens (nac; -35%), but are elevated in the dorsal striatum (+25%) of erbb4 knock-out mice (erbb4 kos) relative to wild-type controls. |
2021-06-18 |
2023-08-13 |
mouse |
| Gang Lei, Fei Liu, Peng Liu, Tong Jiao, Liu Yang, Zheng Chu, Li-Sha Deng, Yan Li, Yong-Hui Dan. Does genetic mouse model of constitutive Hint1 deficiency exhibit schizophrenia-like behaviors? Schizophrenia research. vol 222. 2021-06-17. PMID:32439293. |
total glutamate was decreased in the medial prefrontal cortex, nucleus accumbens (nac), and hip of ko mice. |
2021-06-17 |
2023-08-13 |
mouse |
| José Pedro Prieto, Ximena López Hill, Jessika Urbanavicius, Verónica Sanchez, Xavier Nadal, Cecilia Scorz. Cannabidiol Prevents the Expression of the Locomotor Sensitization and the Metabolic Changes in the Nucleus Accumbens and Prefrontal Cortex Elicited by the Combined Administration of Cocaine and Caffeine in Rats. Neurotoxicity research. vol 38. issue 2. 2021-06-14. PMID:32415526. |
the effect of cbd on putative alterations in the metabolic activity of the medial prefrontal cortex (mpfc) and nucleus accumbens (nac), and its respective subregions (cingulated, prelimbic, and infralimbic cortices, and nac core and shell) associated to the behavioral response, was also investigated. |
2021-06-14 |
2023-08-13 |
rat |
| M J Castelhano-Carlos, S Aslani, N Sous. The Impact of Physical Enrichment in the Structure of the Medial Prefrontal Cortex and Nucleus Accumbens of the Adult Male Rat Brain. Neuroscience. vol 454. 2021-05-14. PMID:32058067. |
herein, we assessed neuronal plasticity as a consequence of living in the phw, by comparing the structure of the medial prefrontal cortex (mpfc) and the nucleus accumbens (nac), two brain areas involved in the circuitry regulating motivation and reward. |
2021-05-14 |
2023-08-13 |
rat |
| Katsumasa Muneoka, Yasunori Oda, Masaaki Iwata, Masaomi Iyo, Kenji Hashimoto, Yukihiko Shirayam. Monoaminergic balances predict non-depression-like phenotype in Learned Helplessness Paradigm. Neuroscience. vol 440. 2021-05-14. PMID:32222554. |
here, we measured the levels of monoamines, including noradrenaline (na), serotonin (5-ht), and dopamine (da), and their metabolites in the medial prefrontal cortex (mpfc), orbitofrontal cortex (ofc), hippocampus, nucleus accumbens (nac), amygdala, and striatum in lh, non-lh, and non-manipulated (naïve) rats. |
2021-05-14 |
2023-08-13 |
rat |
| Alexandra Roldán, Maria J Portella, Frederic Sampedro, Anna Alonso-Solís, Salvador Sarró, Mireia Rabella, Eva M Grasa, Enric Álvarez, Rodrigo Rodríguez, Valle Camacho, Alejandro Fernandez-León, Francisco Fuentes, Josefina Pérez-Blanco, Víctor Pérez, Peter Mckenna, Edith Pomarol-Clotet, Iluminada Corripi. Brain metabolic changes in patients with treatment resistant schizophrenia treated with deep brain stimulation: A series of cases. Journal of psychiatric research. vol 127. 2021-05-14. PMID:32485433. |
increments and decrements of brain activity were observed in regions that included the medial prefrontal cortex, the dorsolateral prefrontal cortex, the anterior cingulate cortex, the caudate nucleus, the nac, the hippocampus and the thalamus. |
2021-05-14 |
2023-08-13 |
Not clear |
| Rebecca S Hofford, Tanner J Euston, Rashaun S Wilson, Katherine R Meckel, Emily G Peck, Arthur Godino, Joseph A Landry, Erin S Calipari, TuKiet T Lam, Drew D Kiral. Granulocyte-Colony Stimulating Factor Reduces Cocaine-Seeking and Downregulates Glutamatergic Synaptic Proteins in Medial Prefrontal Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 7. 2021-04-29. PMID:33361463. |
quantitative assessment of changes in the proteomic landscape in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc) were performed via data-independent acquisition (dia) mass spectrometry analysis. |
2021-04-29 |
2023-08-13 |
rat |
| Joseph Clerke, Patricia Preston-Ferrer, Ioannis S Zouridis, Audrey Tissot, Laura Batti, Fabian F Voigt, Stephane Pagès, Andrea Burgalossi, Manuel Mamel. Output-Specific Adaptation of Habenula-Midbrain Excitatory Synapses During Cocaine Withdrawal. Frontiers in synaptic neuroscience. vol 13. 2021-04-21. PMID:33867967. |
vta neurons receiving lhb inputs project their axons to medial prefrontal cortex (mpfc), nucleus accumbens (nac), and lateral hypothalamus (lh). |
2021-04-21 |
2023-08-13 |
mouse |
| Xiaolu Yu, Mannan Abdul, Bing-Qian Fan, Lilu Zhang, Xing Lin, Yan Wu, Hui Fu, Qisi Lin, Hao Men. The release of exosomes in the medial prefrontal cortex and nucleus accumbens brain regions of chronic constriction injury (CCI) model mice could elevate the pain sensation. Neuroscience letters. vol 723. 2021-04-19. PMID:31981720. |
the medial prefrontal cortex (mpfc) and nucleus accumbens (nac) brain regions are known to involve in pain modulation. |
2021-04-19 |
2023-08-13 |
mouse |
| X Li, L-S Xu, Y-F Xu, Q Yang, Z-X Fang, M Yao, W-Y Che. The gene regulatory network in different brain regions of neuropathic pain mouse models. European review for medical and pharmacological sciences. vol 24. issue 9. 2021-03-31. PMID:32432769. |
neuropathic pain is often associated with structural and functional abnormalities in multiple brain regions, and its regulation has been shown to correspond with the forebrain, including nucleus accumbens (nac), medial prefrontal cortex (mpfc) and periaqueductal gray (pag). |
2021-03-31 |
2023-08-13 |
mouse |
| Jing Wang, Simin Lai, Guodong Li, Ting Zhou, Biao Wang, Fang Cao, Teng Chen, Xia Zhang, Yanjiong Che. Microglial activation contributes to depressive-like behavior in dopamine D3 receptor knockout mice. Brain, behavior, and immunity. vol 83. 2021-03-08. PMID:31626970. |
we previously demonstrated that the dopamine d3 receptor (d3r) inhibitor, ngb2904, increases susceptibility to depressive-like symptoms, elevates pro-inflammatory cytokine expression, and alters brain-derived neurotrophic factor (bdnf) levels in mesolimbic dopaminergic regions, including the medial prefrontal cortex (mpfc), nucleus accumbens (nac), and ventral tegmental area (vta) in mice. |
2021-03-08 |
2023-08-13 |
mouse |
| Omer Horovitz, Ziv Ardi, Shiri Karni Ashkenazi, Gilad Ritov, Rachel Anunu, Gal Richter-Levi. Network Neuromodulation of Opioid and GABAergic Receptors Following a Combination of "Juvenile" and "Adult Stress" in Rats. International journal of molecular sciences. vol 21. issue 15. 2021-02-22. PMID:32751453. |
two weeks following behavioral assessment in adulthood, gabaar α1 and α2 subunits and κ opioid receptor expression levels were measured in the medial prefrontal cortex (mpfc), nucleus accumbens (nac), amygdala, and periaqueductal gray (pag). |
2021-02-22 |
2023-08-13 |
rat |
| Xixi Yang, Yichong Wen, Yuxiang Zhang, Feifei Gao, Jingsi Yang, Zhuojin Yang, Chunxia Ya. Dynamic Changes of Cytoskeleton-Related Proteins Within Reward-Related Brain Regions in Morphine-Associated Memory. Frontiers in neuroscience. vol 14. 2021-02-16. PMID:33584180. |
compared with the nac and dorsal hippocampus, dynamic changes in the medial prefrontal cortex (mpfc) and caudate putamen (cpu) were not very significant. |
2021-02-16 |
2023-08-13 |
mouse |