| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ryan J Mulligan, Bettina Winckle. Regulation of Endosomal Trafficking by Rab7 and Its Effectors in Neurons: Clues from Charcot-Marie-Tooth 2B Disease. Biomolecules. vol 13. issue 9. 2023-09-28. PMID:37759799. |
the prevailing hypothesis to account for cmt2b pathologies is that cmt2b-associated rab7 alleles alter endocytic trafficking of the neurotrophin ngf and its receptor trka and, thereby, disrupt normal trophic signaling in the peripheral nervous system, but other rab7-dependent pathways are also impacted. |
2023-09-28 |
2023-10-07 |
Not clear |
| Ashley J Mason, Austin B Keeler, Farah Kabir, Bettina Winckler, Christopher Deppman. Sympathetic neurons secrete retrogradely transported TrkA on extracellular vesicles. Scientific reports. vol 13. issue 1. 2023-03-04. PMID:36871060. |
proper wiring of the peripheral nervous system relies on neurotrophic signaling via nerve growth factor (ngf). |
2023-03-04 |
2023-08-14 |
mouse |
| Lai-San Wong, Chih-Hung Lee, Yu-Ta Ye. Increased Epidermal Nerve Growth Factor without Small-Fiber Neuropathy in Dermatomyositis. International journal of molecular sciences. vol 23. issue 16. 2022-08-26. PMID:36012289. |
nerve growth factor (ngf) has been recognized as important in nociception by regulating epidermal nerve fiber density and sensitizing the peripheral nervous system. |
2022-08-26 |
2023-08-14 |
Not clear |
| Alexia Tiberi, Simona Capsoni, Antonino Cattane. A Microglial Function for the Nerve Growth Factor: Predictions of the Unpredictable. Cells. vol 11. issue 11. 2022-06-10. PMID:35681529. |
the neurotrophin field has always been dominated by the neurocentric view that the primary target of these molecules must be neurons: this holds true even for the nerve growth factor (ngf), which owes its popularity in the neuroscience community to its trophic and tropic activity towards sensory and sympathetic neurons in the peripheral nervous system, and cholinergic neurons in the cns. |
2022-06-10 |
2023-08-14 |
Not clear |
| Yuta Murai, Akihiro Sekiguchi, Taeko Hirakawa, Seigo Usuki, Yasuyuki Igarashi, Kenji Mond. Evaluation of chiral N,N-dimethyl-sphingosine for the interaction between nerve growth factor and tropomyosin receptor kinase A. Chirality. 2022-03-17. PMID:35297105. |
nerve growth factor (ngf) is one of the peripheral nervous system targeted pain factors that interact with tropomyosin receptor kinase a (trka). |
2022-03-17 |
2023-08-13 |
mouse |
| Levi N Kanu, Joseph B Ciolin. Nerve Growth Factor as an Ocular Therapy: Applications, Challenges, and Future Directions. Seminars in ophthalmology. vol 36. issue 4. 2021-10-28. PMID:33641595. |
the purpose of this article is to review the preclinical and clinical evidence of ngf in various applications, including central and peripheral nervous system, skin, and ophthalmic disorders. |
2021-10-28 |
2023-08-13 |
Not clear |
| Yoshiko Furukaw. [Search for Neuroprotective Compounds -From 4-Methycatechol to Citrus Compounds]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 141. issue 1. 2021-02-15. PMID:33390450. |
after that, we demonstrated that the compounds with a low molecular weight, such as 4-methylcatechol, which elicit stimulatory activity toward ngf synthesis, were useful and practical for therapeutic purposes; as ngf has potent activity on neuronal degeneration in both the central nervous system (cns) and the peripheral nervous system. |
2021-02-15 |
2023-08-13 |
mouse |
| Alessio D'Angelo, Mauro Ceccanti, Carla Petrella, Antonio Greco, Paola Tirassa, Pamela Rosso, Massimo Ralli, Giampiero Ferraguti, Marco Fiore, Marisa Patrizia Messin. Role of neurotrophins in pregnancy, delivery and postpartum. European journal of obstetrics, gynecology, and reproductive biology. vol 247. 2020-11-30. PMID:32058187. |
in particular, nerve growth factor (ngf) and brain-derived neurotrophic factor (bdnf) play a major role in the development, nutrition and growth of the central and peripheral nervous system and in the pathogenesis of neurodegenerative, cardiometabolic and (auto)immune diseases. |
2020-11-30 |
2023-08-13 |
human |
| Rasoul Eslami, Reza Gharakhanlou, Abdolreza Kazemi, Amir Bahador Dakhili, Ghazaleh Sorkhkamanzadeh, Ayob Sheikh. Does Endurance Training Compensate for Neurotrophin Deficiency Following Diabetic Neuropathy? Iranian Red Crescent medical journal. vol 18. issue 10. 2020-09-30. PMID:28184326. |
on the other hand, neurotrophins have consistently been shown to increase in the central and peripheral nervous system following exercise, but the effects of exercise intervention on brain-derived neurotrophic factor (bdnf) and nerve growth factor (ngf) in diabetic neuropathy are not understood. |
2020-09-30 |
2023-08-13 |
Not clear |
| Märta Dahlström, Gunnar Nordvall, Erik Sundström, Elisabet Åkesson, Gunilla Tegerstedt, Maria Eriksdotter, Pontus Forsel. Identification of amino acid residues of nerve growth factor important for neurite outgrowth in human dorsal root ganglion neurons. The European journal of neuroscience. vol 50. issue 9. 2020-09-14. PMID:31301255. |
nerve growth factor (ngf) is an essential neurotrophic factor for the development and maintenance of the central and the peripheral nervous system. |
2020-09-14 |
2023-08-13 |
human |
| Zesergio Melo, Ximena Castillo, Bibiana Moreno-Carranza, María G Ledesma-Colunga, Edith Arnold, Fernando López-Casillas, Xarubet Ruíz-Herrera, Carmen Clapp, Gonzalo Martínez de la Escaler. Vasoinhibin Suppresses Nerve Growth Factor-Induced Differentiation and Survival of PC12 Pheochromocytoma Cells. Neuroendocrinology. vol 109. issue 2. 2020-06-01. PMID:31091528. |
moreover, vasoinhibin compromises nerve growth factor (ngf)-induced neurite outgrowth in primary sensory neurons of the peripheral nervous system. |
2020-06-01 |
2023-08-13 |
Not clear |
| Daniela Meco, Angela Maria Di Francesco, Linda Melotti, Antonio Ruggiero, Riccardo Riccard. Ectopic nerve growth factor prevents proliferation in glioma cells by senescence induction. Journal of cellular physiology. vol 234. issue 5. 2020-03-30. PMID:30417351. |
the neurotrophin nerve growth factor (ngf) affects survival, regulation and differentiation of both central and peripheral nervous system neurons. |
2020-03-30 |
2023-08-13 |
Not clear |
| Abigail Mariga, Mariela Mitre, Moses V Cha. Consequences of brain-derived neurotrophic factor withdrawal in CNS neurons and implications in disease. Neurobiology of disease. vol 97. issue Pt B. 2018-02-12. PMID:27015693. |
in the nervous system, withdrawal of nerve growth factor (ngf) from sympathetic and sensory neurons results in substantial neuronal cell death, signifying a requirement for ngf for the survival of neurons in the peripheral nervous system (pns). |
2018-02-12 |
2023-08-13 |
Not clear |
| F Salvinelli, V Frari, M L Rocco, A d'Eramo, E Salvinelli, B Salvinelli, L Alo. High-pressure physiological saline isotonic solution administration enhances brain NGF and NGF-receptors expression. European review for medical and pharmacological sciences. vol 19. issue 20. 2016-06-22. PMID:26531265. |
nerve growth factor (ngf) is a neurotrophin which promotes and regulates the survival of neurons in the peripheral nervous system. |
2016-06-22 |
2023-08-13 |
Not clear |
| F Salvinelli, V Frari, M L Rocco, P Rosso, L Alo. Enhanced presence of NGF and mast cells number in nasal cavity after autologous stimulation: relation with sensorineural hearing deficit. European review for medical and pharmacological sciences. vol 19. issue 3. 2015-09-09. PMID:25720707. |
nerve growth factor (ngf) is a neurotrophin which promote and regulate the survival of neurons in the peripheral nervous system. |
2015-09-09 |
2023-08-13 |
Not clear |
| S K Kritas, A Caraffa, P Antinolfi, A Saggini, A Pantalone, M Rosati, M Tei, A Speziali, R Saggini, F Pandolfi, G Cerulli, P Cont. Nerve growth factor interactions with mast cells. International journal of immunopathology and pharmacology. vol 27. issue 1. 2014-05-19. PMID:24674674. |
therefore, ngf is an important neuropeptide which mediates the development and functions of the central and peripheral nervous system. |
2014-05-19 |
2023-08-12 |
human |
| Hongtu Yuan, Jingfen Zhang, Huaxiang Liu, Zhenzhong L. The protective effects of resveratrol on Schwann cells with toxicity induced by ethanol in vitro. Neurochemistry international. vol 63. issue 3. 2014-03-07. PMID:23770283. |
schwann cells (scs) are the myelin forming cells in the peripheral nervous system, they play a key role in the pathology of various polyneuropathies and provide trophic support to axons via expression of various neurotrophic factors, such as nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf) and glial cell line-derived neurotrophic factor (gdnf). |
2014-03-07 |
2023-08-12 |
Not clear |
| Martijn P J Dekkers, Vassiliki Nikoletopoulou, Yves-Alain Bard. Cell biology in neuroscience: Death of developing neurons: new insights and implications for connectivity. The Journal of cell biology. vol 203. issue 3. 2014-01-08. PMID:24217616. |
the concept that target tissues determine the survival of neurons has inspired much of the thinking on neuronal development in vertebrates, not least because it is supported by decades of research on nerve growth factor (ngf) in the peripheral nervous system (pns). |
2014-01-08 |
2023-08-12 |
Not clear |
| K L Lankford, E J Arroyo, C-N Liu, C J Somps, M A Zorbas, D L Shelton, M G Evans, S I Hurst, J D Kocsi. Sciatic nerve regeneration is not inhibited by anti-NGF antibody treatment in the adult rat. Neuroscience. vol 241. 2013-12-12. PMID:23531437. |
since ngf also plays important roles in peripheral nervous system development and sensory nerve outgrowth, we asked whether anti-ngf antibodies would adversely impact peripheral nerve regeneration. |
2013-12-12 |
2023-08-12 |
rat |
| Stefania Lucia Nori, Maria Luisa Rocco, Fulvio Florenzano, Maria Teresa Ciotti, Luigi Aloe, Luigi Mann. Increased nerve growth factor signaling in sensory neurons of early diabetic rats is corrected by electroacupuncture. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-05-28. PMID:23710226. |
electroacupuncture (ea) modulates ngf in the peripheral nervous system, being effective for the treatment of dpn symptoms. |
2013-05-28 |
2023-08-12 |
rat |