| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoyin Zhang, Dan Sun, Xin Zhou, Ce Zhang, Qing Yin, Li Chen, Yong Tang, Yonggang Liu, Ludmilla A Morozova-Roch. Proinflammatory S100A9 Stimulates TLR4/NF-\\xce\\xbaB Signaling Pathways Causing Enhanced Phagocytic Capacity of Microglial Cells. Immunology letters vol issue 2023 36870421 |
furthermore, it is uncovered that s100a9 affects phagocytosis of microglia via nf-\xce\xbab signaling pathways. |
2023-03-04 |
2023-03-06 |
Not clear |
| Yan-Ling Liao, Xiao-Yan Zhou, Mu-Huo Ji, Liang-Cheng Qiu, Xiao-Hui Chen, Can-Sheng Gong, Ying Lin, Yan-Hua Guo, Jian-Jun Yan. S100A9 Upregulation Contributes to Learning and Memory Impairments by Promoting Microglia M1 Polarization in Sepsis Survivor Mice. Inflammation vol 44 issue 1 2021 32918665 |
s100a9 upregulation contributes to learning and memory impairments by promoting microglia m1 polarization in sepsis survivor mice. |
2021-10-07 |
2023-01-26 |
mouse |
| Yan-Ling Liao, Xiao-Yan Zhou, Mu-Huo Ji, Liang-Cheng Qiu, Xiao-Hui Chen, Can-Sheng Gong, Ying Lin, Yan-Hua Guo, Jian-Jun Yan. S100A9 Upregulation Contributes to Learning and Memory Impairments by Promoting Microglia M1 Polarization in Sepsis Survivor Mice. Inflammation vol 44 issue 1 2021 32918665 |
taken together, our study suggests that s100a9 upregulation might contribute to learning and memory impairments by promoting microglia m1 polarization in sepsis survivors, whereas s100a9 inhibition might provide a potential therapeutic target for sae. |
2021-10-07 |
2023-01-26 |
mouse |
| Cristina Contini, Alessandra Olianas, Simone Serrao, Carla Deriu, Federica Iavarone, Mozhgan Boroumand, Alessandra Bizzarro, Alessandra Lauria, Gavino Faa, Massimo Castagnola, Irene Messana, Barbara Manconi, Carlo Masullo, Tiziana Cabra. Top-Down Proteomics of Human Saliva Highlights Anti-inflammatory, Antioxidant, and Antimicrobial Defense Responses in Alzheimer Disease. Frontiers in neuroscience vol 15 issue 2021 34121996 |
the salivary protein profile of ad patients was characterized by significantly higher levels of some multifaceted proteins and peptides that were either specific to the oral cavity or also expressed in other body districts: (i) peptides involved in the homeostasis of the oral cavity; (ii) proteins acting as ros/rns scavengers and with a neuroprotective role, such as s100a8, s100a9, and their glutathionylated and nitrosylated proteoforms; cystatin b and glutathionylated and dimeric derivatives; (iii) proteins with antimicrobial activity, such as \xce\xb1-defensins, cystatins a and b, histatin 1, statherin, and thymosin \xce\xb24, this last with a neuroprotective role at the level of microglia. |
2021-09-06 |
2023-01-26 |
human |
| Chao Wang, Igor A Iashchishyn, Jonathan Pansieri, Sofie Nystr\\xc3\\xb6m, Oxana Klementieva, John Kara, Istvan Horvath, Roman Moskalenko, Reza Rofougaran, Gunnar Gouras, Gabor G Kovacs, S K Shankar, Ludmilla A Morozova-Roch. S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer's Disease. Scientific reports vol 8 issue 1 2019 30150640 |
by analyzing the tbi and ad human brain tissues, we demonstrated that in post-tbi tissues s100a9, produced by neurons and microglia, becomes drastically abundant compared to a\xce\xb2 and contributes to both precursor-plaque formation and intracellular amyloid oligomerization. |
2019-10-29 |
2023-01-26 |
human |