All Relations between s100a9 and microglial cell

Publication Sentence Publish Date Extraction Date Species
Burak Uzay, Aslıhan Bahadır-Varol, Fatma Özlem Hökelekli, Murat Yılmaz, Emre Cem Esen, Koray Başar, Yavuz Ayhan, Turgay Dalkara, Emine Eren-Koça. FGF2 gene's antisense protein, NUDT6, plays a depressogenic role by promoting inflammation and suppressing neurogenesis without altering FGF2 signalling. The Journal of physiology. 2024-03-12. PMID:38468384. instead, nudt6 acted by inducing inflammatory signalling, specifically by increasing s100 calcium binding protein a9 (s100a9) levels, activating nuclear factor-kappa b-p65 (nf-κb-p65), and elevating microglia numbers along with a reduction in neurogenesis. 2024-03-12 2024-03-14 rat
Ning Huang, Jun Tang, Xiaoyao Yi, Maoxin Zhang, Bin Li, Yuan Cheng, Jin Che. Glioma-derived S100A9 polarizes M2 microglia to inhibit CD8+T lymphocytes for immunosuppression via αvβ3 integrin/AKT1/TGFβ1. Biochimica et biophysica acta. Molecular cell research. 2023-10-31. PMID:37907196. these molecular mechanisms were related to the interaction of s100a9 with αvβ3 integrin and the subsequent activation of akt1 in microglia. 2023-10-31 2023-11-08 mouse
Ning Huang, Jun Tang, Xiaoyao Yi, Maoxin Zhang, Bin Li, Yuan Cheng, Jin Che. Glioma-derived S100A9 polarizes M2 microglia to inhibit CD8+T lymphocytes for immunosuppression via αvβ3 integrin/AKT1/TGFβ1. Biochimica et biophysica acta. Molecular cell research. 2023-10-31. PMID:37907196. glioma-derived s100a9 polarizes m2 microglia to inhibit cd8+t lymphocytes for immunosuppression via αvβ3 integrin/akt1/tgfβ1. 2023-10-31 2023-11-08 mouse
Xiaoyin Zhang, Dan Sun, Xin Zhou, Ce Zhang, Qing Yin, Li Chen, Yong Tang, Yonggang Liu, Ludmilla A Morozova-Roch. Proinflammatory S100A9 Stimulates TLR4/NF-κB Signaling Pathways Causing Enhanced Phagocytic Capacity of Microglial Cells. Immunology letters. 2023-03-04. PMID:36870421. furthermore, it is uncovered that s100a9 affects phagocytosis of microglia via nf-κb signaling pathways. 2023-03-04 2023-08-14 Not clear
Yan-Ling Liao, Xiao-Yan Zhou, Mu-Huo Ji, Liang-Cheng Qiu, Xiao-Hui Chen, Can-Sheng Gong, Ying Lin, Yan-Hua Guo, Jian-Jun Yan. S100A9 Upregulation Contributes to Learning and Memory Impairments by Promoting Microglia M1 Polarization in Sepsis Survivor Mice. Inflammation. vol 44. issue 1. 2021-10-07. PMID:32918665. taken together, our study suggests that s100a9 upregulation might contribute to learning and memory impairments by promoting microglia m1 polarization in sepsis survivors, whereas s100a9 inhibition might provide a potential therapeutic target for sae. 2021-10-07 2023-08-13 mouse
Yan-Ling Liao, Xiao-Yan Zhou, Mu-Huo Ji, Liang-Cheng Qiu, Xiao-Hui Chen, Can-Sheng Gong, Ying Lin, Yan-Hua Guo, Jian-Jun Yan. S100A9 Upregulation Contributes to Learning and Memory Impairments by Promoting Microglia M1 Polarization in Sepsis Survivor Mice. Inflammation. vol 44. issue 1. 2021-10-07. PMID:32918665. s100a9 upregulation contributes to learning and memory impairments by promoting microglia m1 polarization in sepsis survivor mice. 2021-10-07 2023-08-13 mouse
Cristina Contini, Alessandra Olianas, Simone Serrao, Carla Deriu, Federica Iavarone, Mozhgan Boroumand, Alessandra Bizzarro, Alessandra Lauria, Gavino Faa, Massimo Castagnola, Irene Messana, Barbara Manconi, Carlo Masullo, Tiziana Cabra. Top-Down Proteomics of Human Saliva Highlights Anti-inflammatory, Antioxidant, and Antimicrobial Defense Responses in Alzheimer Disease. Frontiers in neuroscience. vol 15. 2021-09-06. PMID:34121996. the salivary protein profile of ad patients was characterized by significantly higher levels of some multifaceted proteins and peptides that were either specific to the oral cavity or also expressed in other body districts: (i) peptides involved in the homeostasis of the oral cavity; (ii) proteins acting as ros/rns scavengers and with a neuroprotective role, such as s100a8, s100a9, and their glutathionylated and nitrosylated proteoforms; cystatin b and glutathionylated and dimeric derivatives; (iii) proteins with antimicrobial activity, such as α-defensins, cystatins a and b, histatin 1, statherin, and thymosin β4, this last with a neuroprotective role at the level of microglia. 2021-09-06 2023-08-13 human
Chao Wang, Igor A Iashchishyn, Jonathan Pansieri, Sofie Nyström, Oxana Klementieva, John Kara, Istvan Horvath, Roman Moskalenko, Reza Rofougaran, Gunnar Gouras, Gabor G Kovacs, S K Shankar, Ludmilla A Morozova-Roch. S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer's Disease. Scientific reports. vol 8. issue 1. 2019-10-29. PMID:30150640. by analyzing the tbi and ad human brain tissues, we demonstrated that in post-tbi tissues s100a9, produced by neurons and microglia, becomes drastically abundant compared to aβ and contributes to both precursor-plaque formation and intracellular amyloid oligomerization. 2019-10-29 2023-08-13 human
Tae-Young Ha, Keun-A Chang, Jeong a Kim, Hye-Sun Kim, Seonghan Kim, Young Hae Chong, Yoo-Hun Su. S100a9 knockdown decreases the memory impairment and the neuropathology in Tg2576 mice, AD animal model. PloS one. vol 5. issue 1. 2010-05-20. PMID:20098622. the endogenous expression of s100a9 was induced by treatment with abeta or ct peptides in a microglia cell line, bv2 cells. 2010-05-20 2023-08-12 mouse