| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yi Chung, Jia-Ling Wu, Wen-Ching Huan. Effects of prebiotics on intestinal physiology, neuropsychological function, and exercise capacity of mice with sleep deprivation. Food research international (Ottawa, Ont.) vol 165 issue 2023 36869551 |
results showed that sleep deprivation caused intestinal inflammation (increased tnfa and il1b) and decreased intestinal permeability with a significant decrease in the tight junction genes (ocln, cldn1, tjp1, and tjp2) of intestine and brain. |
2023-03-04 |
2023-03-06 |
mouse |
| D\\xc3\\xa1niel Kuti, Zsuzsanna Winkler, Krisztina Horv\\xc3\\xa1th, Bal\\xc3\\xa1zs Juh\\xc3\\xa1sz, Melinda Paholcsek, Anik\\xc3\\xb3 St\\xc3\\xa1gel, Gabriella Guly\\xc3\\xa1s, Levente Czegl\\xc3\\xa9di, Szilam\\xc3\\xa9r Ferenczi, Krisztina J Kov\\xc3\\xa1c. Gastrointestinal (non-systemic) antibiotic rifaximin differentially affects chronic stress-induced changes in colon microbiome and gut permeability without effect on behavior. Brain, behavior, and immunity vol 84 issue 2021 31821847 |
rifaximin treatment decreased clostridium concentration, gut permeability and lps plasma concentration and increased colonic expression of tight junction proteins (tjp1, tjp2) and occludin. |
2021-03-09 |
2023-01-26 |
mouse |
| Michael Camilleri, Paula Carlson, Nelson Valentin, Andres Acosta, Jessica O'Neill, Deborah Eckert, Roy Dyer, Jie Na, Eric W Klee, Joseph A Murra. Pilot study of small bowel mucosal gene expression in patients with irritable bowel syndrome with diarrhea. American journal of physiology. Gastrointestinal and liver physiology vol 311 issue 3 2017 27445342 |
among the 14 nominally upregulated genes, there was clustering of barrier and pdz domains (tjp1, tjp2, tjp3, cldn4, inadl, and magi1) and clustering of downregulated genes (ccl20, tlr1, il1b, and tlr8). |
2017-06-21 |
2023-01-25 |
Not clear |
| Marcin Kazmierczak, Suzan L Harris, Piotr Kazmierczak, Prahar Shah, Valentin Starovoytov, Kevin K Ohlemiller, Martin Schwande. Progressive Hearing Loss in Mice Carrying a Mutation in Usp53. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 35 issue 47 2016 26609154 |
usp53 colocalizes and interacts with the tight junction scaffolding proteins tjp1 and tjp2 in polarized epithelial cells, suggesting that usp53 is part of the tight junction complex. |
2016-03-14 |
2023-01-25 |
mouse |