All Relations between trpv1 and trpv4

Publication Sentence Publish Date Extraction Date Species
José Martín-Cruces, Benjamín Martín-Biedma, Yolanda García-Mesa, Patricia Cuendias, Juan J Gaite, Olivia García-Suárez, Juan L Cobo, José A Veg. Exploring somatosensory innervation of the human lip: A focus on the vermilion. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 2023-09-23. PMID:37741584. the aim of this study was to investigate the somatosensory innervation of human lips, focusing on sensory corpuscles and the presence of mechano-gated (asic2, piezo2, and trpv4) and thermosensing (trpv1, trpm2, and rpm8) ion channels within them. 2023-09-23 2023-10-07 human
Amanda B Sidwell, Celia McClintock, Katharine I Beča, Susan E Campbell, Beatrice M Girard, Margaret A Vizzar. Repeated variate stress increased voiding frequency and altered TrpV1 and TrpV4 transcript expression in lower urinary tract (LUT) pathways in female mice. Frontiers in urology. vol 2. 2023-09-11. PMID:37692906. quantitative pcr demonstrated significant (p ≤ 0.05) changes in trpv1 and trpv4 mrna expression between control and rvs cohorts in the urothelium, lumbosacral spinal cord, and drg. 2023-09-11 2023-10-07 mouse
Gregory Luke Smit. Hair Regrowth with Novel Hemp Extract: A Case Series. International journal of trichology. vol 15. issue 1. 2023-06-12. PMID:37305187. the three cannabinoids are fat-soluble and poorly absorbed past the epidermis, but topical application easily reaches hair follicles where they act as partial or full cb1 antagonist and agonist of transient receptor potential vanilloid-1 (trpv1) and vanilloid receptor-4 (trpv4). 2023-06-12 2023-08-14 Not clear
Rosica S Petrova, Nikhil Nair, Nandini Bavana, Yadi Chen, Kevin L Schey, Paul J Donaldso. Modulation of Membrane Trafficking of AQP5 in the Lens in Response to Changes in Zonular Tension Is Mediated by the Mechanosensitive Channel TRPV1. International journal of molecular sciences. vol 24. issue 10. 2023-05-27. PMID:37240426. in contrast, mimicking the actions of pilocarpine by blocking trpv4 and then activating trpv1 resulted in sustained increase in pressure and the removal of aqp5 from the anterior influx and equatorial efflux zones. 2023-05-27 2023-08-14 mouse
Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology. vol 103. issue 4. 2023-03-04. PMID:36870285. here, we investigated how trpv1 and trpv4 channels are involved in orn regeneration. 2023-03-04 2023-08-14 mouse
Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology. vol 103. issue 4. 2023-03-04. PMID:36870285. trpv1 knockout (ko), trpv4 ko, and wild-type (wt) mice were used to model methimazole-induced olfactory dysfunction. 2023-03-04 2023-08-14 mouse
Hideki Sakatani, Masamitsu Kono, Tatsuya Shiga, Hiroki Kuwazoe, Denisa Nanushaj, Ibu Matsuzaki, Shin-Ichi Murata, Masayasu Miyajima, Yuka Okada, Shizuya Saika, Muneki Hotom. The Roles of Transient Receptor Potential Vanilloid 1 and 4 in Olfactory Regeneration. Laboratory investigation; a journal of technical methods and pathology. vol 103. issue 4. 2023-03-04. PMID:36870285. orn regeneration was regulated by the interaction between trpv1 and trpv4. 2023-03-04 2023-08-14 mouse
Arzu Citak, Erkan Kilinc, Ibrahim Ethem Torun, Seyit Ankarali, Yasar Dagistan, Hamit Yolda. The effects of certain TRP channels and voltage-gated KCNQ/Kv7 channel opener retigabine on calcitonin gene-related peptide release in the trigeminovascular system. Cephalalgia : an international journal of headache. 2022-07-21. PMID:35861239. we investigated the effects of certain transient receptor potential (trp) channels the vanilloid 1 and 4 (trpv1 and trpv4), the ankyrin 1 (trpa1), and metastatin type 8 (trpm8), and voltage-gated potassium channel (kv7) opener retigabine on calcitonin gene-related peptide release from peripheral (dura mater and trigeminal ganglion) and central (trigeminal nucleus caudalis) trigeminal components of rats. 2022-07-21 2023-08-14 rat
Sanjay S Aripaka, Rachid Bech-Azeddine, Louise M Jørgensen, Jens D Mikkelse. Transient receptor potential (TRP) channels mRNA transcripts in the lumbar intervertebral discs: biomarkers for inflammation, pain, disability, and clinical outcome. Molecular and cellular biochemistry. 2022-06-23. PMID:35737198. this study investigates the expression of the trp channel subtypes trpv1, trpv4, trpc6, trpm2, trpm8 in lumbar intervertebral disc (ivd) biopsies from patients with chronic low back pain (lbp). 2022-06-23 2023-08-14 Not clear
Andrew O Jo, Monika Lakk, Christopher N Rudzitis, David Križa. TRPV4 and TRPC1 channels mediate the response to tensile strain in mouse Müller cells. Cell calcium. vol 104. 2022-04-10. PMID:35398674. transcript levels in purified glia were trpc1>piezo1>trpv2>trpv4>>trpv1>trpa1. 2022-04-10 2023-08-13 mouse
Yosuke Nakazawa, Rosica S Petrova, Yuki Sugiyama, Noriaki Nagai, Hiroomi Tamura, Paul J Donaldso. Regulation of the Membrane Trafficking of the Mechanosensitive Ion Channels TRPV1 and TRPV4 by Zonular Tension, Osmotic Stress and Activators in the Mouse Lens. International journal of molecular sciences. vol 22. issue 23. 2021-12-10. PMID:34884463. mouse lenses were incubated in either pilocarpine or tropicamide to alter zonular tension, exposed to osmotic stress, or the trpv1 and trpv4 activators capsaicin andgsk1016790a (gsk101), and the effect on the trpv1 and trpv4 membrane trafficking in peripheral fiber cells visualized using confocal microscopy. 2021-12-10 2023-08-13 mouse
Yen Lai, Wolfgang Bäumer, Constanza Meneses, Donald M Roback, James B Robertson, Santosh K Mishra, B Duncan X Lascelles, Michael W Nola. Irradiation of the Normal Murine Tongue Causes Upregulation and Activation of Transient Receptor Potential (TRP) Ion Channels. Radiation research. vol 196. issue 4. 2021-11-29. PMID:34324688. ex vivo calcium imaging experiments demonstrated that the proportions of tg neurons responding to histamine (an activator of trpv1, trpv4 and trpa1), tnf-α (an activator of trpv1, trpv2 and trpv4), and capsaicin (a trpv1 agonist), were increased as early as one day after tongue irradiation; these changes persisted for at least 21 days. 2021-11-29 2023-08-13 mouse
Shota Tobori, Haruka Hiyama, Takahito Miyake, Yuichi Yano, Kazuki Nagayasu, Hisashi Shirakawa, Takayuki Nakagawa, Yasuo Mori, Shuji Kanek. MrgprB4 in trigeminal neurons expressing TRPA1 modulates unpleasant sensations. Journal of pharmacological sciences. vol 146. issue 4. 2021-11-12. PMID:34116733. we examined small populations of mrgprb4-positive neurons in the trigeminal ganglion and the dorsal root ganglion, and most of these were sensitive to transient receptor potential ankyrin 1 (trpa1) agonist but not trpv1, trpm8, or trpv4 agonists. 2021-11-12 2023-08-13 mouse
Claudia García-Rodríguez, Iván D Bravo-Tobar, Yorley Duarte, Luis C Barrio, Juan C Sáe. Contribution of non-selective membrane channels and receptors in epilepsy. Pharmacology & therapeutics. 2021-09-18. PMID:34481811. this review is focused on a set of non-selective membrane channels (permeable to ions and small molecules), including channels and ionotropic receptors of neurons, astrocytes, and microglia, such as: the hemichannels formed by cx43 and panx1; the purinergic p2x7 receptors; the transient receptor potential vanilloid (trpv1 and trpv4) channels; calcium homeostasis modulators (calhms); transient receptor potential canonical (trpc) channels; transient receptor potential melastatin (trpm) channels; voltage-dependent anion channels (vdacs) and volume-regulated anion channels (vracs), which all have in common being activated by epileptic activity and the capacity to exacerbate seizure intensity. 2021-09-18 2023-08-13 Not clear
Mikayla L Price, Yen-Hao Erik Lai, Karen L Marcus, James B Robertson, B Duncan X Lascelles, Michael W Nola. Early radiation-induced oral pain signaling responses are reduced with pentoxifylline treatment. Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association. vol 62. issue 2. 2021-06-02. PMID:33350542. responsiveness of afferent sensory trigeminal neurons to tnf-α, a trpv1 agonist (capsaicin), and a partial trpv4 agonist (histamine) was measured via calcium imaging. 2021-06-02 2023-08-13 mouse
Chanté Muller, Patricia H Reggi. An Analysis of the Putative CBD Binding Site in the Ionotropic Cannabinoid Receptors. Frontiers in cellular neuroscience. vol 14. 2020-12-29. PMID:33362478. trpv2, along with trpv1, trpv3, trpv4, trpa1, and trpm8 all have the capability to be modulated by cannabinoid ligands and are located in the peripheral nervous system. 2020-12-29 2023-08-13 Not clear
Chanté Muller, Paula Morales, Patricia H Reggi. Cannabinoid Ligands Targeting TRP Channels. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:30697147. to date, six trp channels from the three subfamilies mentioned above have been reported to mediate cannabinoid activity: trpv1, trpv2, trpv3, trpv4, trpa1, and trpm8. 2020-10-01 2023-08-13 Not clear
Hui Kan Hong, Yi Ma, Hengtao Xi. TRPV1 and spinal astrocyte activation contribute to remifentanil-induced hyperalgesia in rats. Neuroreport. vol 30. issue 16. 2020-07-14. PMID:31568203. protein expressions of trpv1 and protein kinase c (pkc) in dorsal root ganglion were assayed by western blotting and mrna level of trpv1, trpa1, trpv4, and trpm8 were assayed by real-time pcr. 2020-07-14 2023-08-13 rat
Simone Li Puma, Lorenzo Landini, Sergio J Macedo, Viola Seravalli, Ilaria M Marone, Elisabetta Coppi, Riccardo Patacchini, Pierangelo Geppetti, Serena Materazzi, Romina Nassini, Francesco De Log. TRPA1 mediates the antinociceptive properties of the constituent of Crocus sativus L., safranal. Journal of cellular and molecular medicine. vol 23. issue 3. 2020-06-25. PMID:30636360. safranal by binding to specific cysteine/lysine residues, stimulates trpa1, but not the trp vanilloid 1 and 4 channels (trpv1 and trpv4), evoking calcium responses and currents in human cells and rat and mouse dorsal root ganglion (drg) neurons. 2020-06-25 2023-08-13 mouse
Simone Li Puma, Lorenzo Landini, Sergio J Macedo, Viola Seravalli, Ilaria M Marone, Elisabetta Coppi, Riccardo Patacchini, Pierangelo Geppetti, Serena Materazzi, Romina Nassini, Francesco De Log. TRPA1 mediates the antinociceptive properties of the constituent of Crocus sativus L., safranal. Journal of cellular and molecular medicine. vol 23. issue 3. 2020-06-25. PMID:30636360. after exposure to safranal the ability of allyl isothiocyanate (trpa1 agonist), but not that of capsaicin (trpv1 agonist) or gsk1016790a (trpv4 agonist), to evoke currents in drg neurons, contraction of urinary bladder strips and cgrp release from spinal cord slices in rats, and acute nociception in mice underwent desensitization. 2020-06-25 2023-08-13 mouse