| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Beatrice M Girard, Liana Merrill, Susan Malley, Margaret A Vizzar. Increased TRPV4 expression in urinary bladder and lumbosacral dorsal root ganglia in mice with chronic overexpression of NGF in urothelium. Journal of molecular neuroscience : MN. vol 51. issue 2. 2014-05-30. PMID:23690258. |
transient receptor potential vanilloid (trpv) family member 4 (trpv4) expression has been demonstrated in urothelial cells and dorsal root ganglion (drg) neurons, and roles in normal micturition reflexes as well as micturition dysfunction have been suggested. |
2014-05-30 |
2023-08-12 |
mouse |
| Beatrice M Girard, Liana Merrill, Susan Malley, Margaret A Vizzar. Increased TRPV4 expression in urinary bladder and lumbosacral dorsal root ganglia in mice with chronic overexpression of NGF in urothelium. Journal of molecular neuroscience : MN. vol 51. issue 2. 2014-05-30. PMID:23690258. |
these studies expand upon the target tissue dependence of trpv4 expression in the urinary bladder and lumbosacral drg using a recently characterized transgenic mouse model with chronic overexpression of nerve growth factor (ngf-oe) in the urothelium. |
2014-05-30 |
2023-08-12 |
mouse |
| Beatrice M Girard, Liana Merrill, Susan Malley, Margaret A Vizzar. Increased TRPV4 expression in urinary bladder and lumbosacral dorsal root ganglia in mice with chronic overexpression of NGF in urothelium. Journal of molecular neuroscience : MN. vol 51. issue 2. 2014-05-30. PMID:23690258. |
immunohistochemistry with image analyses, real-time quantitative polymerase chain reaction, and western blotting were used to determine trpv4 protein and transcript expression in the urinary bladder (urothelium + suburothelium, detrusor) and lumbosacral drg from littermate wild-type (wt) and ngf-oe mice. |
2014-05-30 |
2023-08-12 |
mouse |
| Beatrice M Girard, Liana Merrill, Susan Malley, Margaret A Vizzar. Increased TRPV4 expression in urinary bladder and lumbosacral dorsal root ganglia in mice with chronic overexpression of NGF in urothelium. Journal of molecular neuroscience : MN. vol 51. issue 2. 2014-05-30. PMID:23690258. |
trpv4 transcript and protein expression was significantly (p ≤ 0.001) increased in the urothelium + suburothelium and suburothelial nerve plexus of the urinary bladder and in small- and medium-sized lumbosacral (l1, l2, l6-s1) drg cells from ngf-oe mice compared to littermate wt mice. |
2014-05-30 |
2023-08-12 |
mouse |
| Beatrice M Girard, Liana Merrill, Susan Malley, Margaret A Vizzar. Increased TRPV4 expression in urinary bladder and lumbosacral dorsal root ganglia in mice with chronic overexpression of NGF in urothelium. Journal of molecular neuroscience : MN. vol 51. issue 2. 2014-05-30. PMID:23690258. |
ongoing studies are characterizing the functional roles of trpv4 expression in the sensory limb (drg, urothelium) of the micturition reflex. |
2014-05-30 |
2023-08-12 |
mouse |
| Gisela Segond von Banchet, Michael K Boettger, Christian König, Yoichiro Iwakura, Rolf Bräuer, Hans-Georg Schaibl. Neuronal IL-17 receptor upregulates TRPV4 but not TRPV1 receptors in DRG neurons and mediates mechanical but not thermal hyperalgesia. Molecular and cellular neurosciences. vol 52. 2013-07-22. PMID:23147107. |
neuronal il-17 receptor upregulates trpv4 but not trpv1 receptors in drg neurons and mediates mechanical but not thermal hyperalgesia. |
2013-07-22 |
2023-08-12 |
mouse |
| Hui Wei, Yang Zhang, Zhen-Zhen Fan, Hong-You Ge, Lars Arendt-Nielsen, Hong Jiang, Wei Yao, Shou-Wei Yu. Effects of colchicine-induced microtubule depolymerization on TRPV4 in rats with chronic compression of the dorsal root ganglion. Neuroscience letters. vol 534. 2013-06-18. PMID:23262088. |
effects of colchicine-induced microtubule depolymerization on trpv4 in rats with chronic compression of the dorsal root ganglion. |
2013-06-18 |
2023-08-12 |
rat |
| Hui Wei, Yang Zhang, Zhen-Zhen Fan, Hong-You Ge, Lars Arendt-Nielsen, Hong Jiang, Wei Yao, Shou-Wei Yu. Effects of colchicine-induced microtubule depolymerization on TRPV4 in rats with chronic compression of the dorsal root ganglion. Neuroscience letters. vol 534. 2013-06-18. PMID:23262088. |
the aim of this study was to investigate the effect of colchicine-induced microtubule depolymerization on allodynia in rats with chronic compression of the dorsal root ganglion (drg) (ccd) and the effect of colchicine on transient receptor potential vanilloid 4 (trpv4). |
2013-06-18 |
2023-08-12 |
rat |
| Hui Wei, Yang Zhang, Zhen-Zhen Fan, Hong-You Ge, Lars Arendt-Nielsen, Hong Jiang, Wei Yao, Shou-Wei Yu. Effects of colchicine-induced microtubule depolymerization on TRPV4 in rats with chronic compression of the dorsal root ganglion. Neuroscience letters. vol 534. 2013-06-18. PMID:23262088. |
in addition, colchicine resulted in reduction and advance of trpv4 currents in both drg neurons and hek293-trpv4 cells. |
2013-06-18 |
2023-08-12 |
rat |
| Liping Ning, Chuanwei Wang, Xinli Ding, Yang Zhang, Xuping Wang, Shouwei Yu. Functional interaction of TRPV4 channel protein with annexin A2 in DRG. Neurological research. vol 34. issue 7. 2013-06-13. PMID:22762361. |
functional interaction of trpv4 channel protein with annexin a2 in drg. |
2013-06-13 |
2023-08-12 |
Not clear |
| Liping Ning, Chuanwei Wang, Xinli Ding, Yang Zhang, Xuping Wang, Shouwei Yu. Functional interaction of TRPV4 channel protein with annexin A2 in DRG. Neurological research. vol 34. issue 7. 2013-06-13. PMID:22762361. |
transient receptor potential vanilloid 4 (trpv4) is a ca(2+)-permeable, non-selective cation channel that is involved in the transmission of pain signals mediated by dorsal root ganglion (drg). |
2013-06-13 |
2023-08-12 |
Not clear |
| Liping Ning, Chuanwei Wang, Xinli Ding, Yang Zhang, Xuping Wang, Shouwei Yu. Functional interaction of TRPV4 channel protein with annexin A2 in DRG. Neurological research. vol 34. issue 7. 2013-06-13. PMID:22762361. |
in this paper, we evaluated the functional interaction of trpv4 with annexin a2 in drg. |
2013-06-13 |
2023-08-12 |
Not clear |
| Juan Huai, Yang Zhang, Qing-Mei Liu, Hong-You Ge, Lars Arendt-Nielsen, Hong Jiang, Shou-Wei Yu. Interaction of transient receptor potential vanilloid 4 with annexin A2 and tubulin beta 5. Neuroscience letters. vol 512. issue 1. 2013-05-10. PMID:22309793. |
coimmunoprecipitation of the rat dorsal root ganglion was performed to validly conform the interaction of trpv4 with the other two proteins. |
2013-05-10 |
2023-08-12 |
human |
| Wei-Hsin Chen, Jason T C Tzen, Ching Liang Hsieh, Yung Hsiang Chen, Tzu-Jou Lin, Shih-Yin Chen, Yi-Wen Li. Attenuation of TRPV1 and TRPV4 Expression and Function in Mouse Inflammatory Pain Models Using Electroacupuncture. Evidence-based complementary and alternative medicine : eCAM. vol 2012. 2012-12-24. PMID:23258994. |
the protein levels of trpv1 and trpv4 in drg (dorsal root ganglion) neurons were both increased at day 4 after the initiation of inflammatory pain and were attenuated by ea, as demonstrated by immunostaining and western blot analysis. |
2012-12-24 |
2023-08-12 |
mouse |
| Ting-Ting Liu, Hong-Sheng Bi, Shan-Yun Lv, Xing-Rong Wang, Shou-Wei Yu. Inhibition of the expression and function of TRPV4 by RNA interference in dorsal root ganglion. Neurological research. vol 32. issue 5. 2010-09-29. PMID:19278577. |
inhibition of the expression and function of trpv4 by rna interference in dorsal root ganglion. |
2010-09-29 |
2023-08-12 |
Not clear |
| Ting-Ting Liu, Hong-Sheng Bi, Shan-Yun Lv, Xing-Rong Wang, Shou-Wei Yu. Inhibition of the expression and function of TRPV4 by RNA interference in dorsal root ganglion. Neurological research. vol 32. issue 5. 2010-09-29. PMID:19278577. |
transient receptor potential vanilloid 4 (trpv4) calcium channel is an essential mediator of spinal nociceptive transmission in dorsal root ganglion (drg), but its mechanism in pain transmission is poorly understood. |
2010-09-29 |
2023-08-12 |
Not clear |
| Ting-Ting Liu, Hong-Sheng Bi, Shan-Yun Lv, Xing-Rong Wang, Shou-Wei Yu. Inhibition of the expression and function of TRPV4 by RNA interference in dorsal root ganglion. Neurological research. vol 32. issue 5. 2010-09-29. PMID:19278577. |
the present study intended to evaluate the effect of small interfering rna (sirna) on the expression and function of trpv4 in drg neurons and its possible usage in pain relief treatment. |
2010-09-29 |
2023-08-12 |
Not clear |
| Xin-Li Ding, Yong-Hui Wang, Li-Ping Ning, Yang Zhang, Hong-You Ge, Hong Jiang, Rong Wang, Shou-Wei Yu. Involvement of TRPV4-NO-cGMP-PKG pathways in the development of thermal hyperalgesia following chronic compression of the dorsal root ganglion in rats. Behavioural brain research. vol 208. issue 1. 2010-05-03. PMID:19948193. |
ruthenium red (1 nmol), trpv4 as (40 microg, daily for 7 days) or l-name (300 nmol) decreased nitrite (an index of nitric oxide formation) in the drg of ccd rats. |
2010-05-03 |
2023-08-12 |
rat |
| Sravan Mandadi, Takaaki Sokabe, Koji Shibasaki, Kimiaki Katanosaka, Atsuko Mizuno, Aziz Moqrich, Ardem Patapoutian, Tomoko Fukumi-Tominaga, Kazue Mizumura, Makoto Tominag. TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP. Pflugers Archiv : European journal of physiology. vol 458. issue 6. 2009-12-31. PMID:19669158. |
it has been proposed that heat-activation of trpv3 and/or trpv4 in the skin may release diffusible molecules which would then activate termini of neighboring dorsal root ganglion (drg) neurons. |
2009-12-31 |
2023-08-12 |
mouse |
| Nicole Alessandri-Haber, Olayinka A Dina, Xiaoje Chen, Jon D Levin. TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 19. 2009-05-28. PMID:19439599. |
single-cell reverse transcription-pcr showed that messenger rnas for trpv4, trpc1, and trpc6 are frequently coexpressed in drg neurons. |
2009-05-28 |
2023-08-12 |
rat |