| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Enomoto, K Ogita, D Han, Y Yoned. Differential potentiation by spermidine of abilities of a variety of displacers for [3H]MK-801 binding in hippocampal synaptic membranes. Neuroscience research vol 16 issue 3 1993 8098144 |
differential potentiation by spermidine of abilities of a variety of displacers for [3h]mk-801 binding in hippocampal synaptic membranes. |
1993-06-07 |
2022-01-10 |
Not clear |
| R Enomoto, K Ogita, D Han, Y Yoned. Differential potentiation by spermidine of abilities of a variety of displacers for [3H]MK-801 binding in hippocampal synaptic membranes. Neuroscience research vol 16 issue 3 1993 8098144 |
the binding of [3h]mk-801 was slowly equilibrated in 16 h. when examined in hippocampal synaptic membranes, the binding at equilibrium was markedly displaced by numerous noncompetitive antagonists for the nmda receptor. |
1993-06-07 |
2022-01-10 |
Not clear |
| S Papas, V Cr\\xc3\\xa9pel, Y Ben-Ar. The NMDA receptor contributes to anoxic aglycemic induced irreversible inhibition of synaptic transmission. Brain research vol 607 issue 1-2 1993 8386976 |
percent recovery of ca1 field epsp amplitude following various anoxic aglycemic (aa) periods was examined in rat hippocampal slices superfused with mk-801 (0.1 microm, 1 microm, 10 microm) or mg(2+)-free artificial cerebrospinal fluid. |
1993-06-03 |
2022-01-10 |
Not clear |
| Y Wada, H Hasegawa, M Nakamura, N Yamaguch. Action of the N-methyl-D-aspartate receptor antagonist MK-801 against focal seizure activity from the feline hippocampus. Neuropsychobiology vol 26 issue 4 1993 1299796 |
rather, mk-801 at a higher dose induced hippocampal seizure status in some of the cats tested. |
1993-05-18 |
2022-01-10 |
Not clear |
| M R Domenici, R Longo, A S de Carolis, C Frank, S Sagratell. Protective actions of 21-aminosteroids and MK-801 on hypoxia-induced electrophysiological changes in rat hippocampal slices. European journal of pharmacology vol 233 issue 2-3 1993 8467875 |
protective actions of 21-aminosteroids and mk-801 on hypoxia-induced electrophysiological changes in rat hippocampal slices. |
1993-05-11 |
2022-01-10 |
Not clear |
| M R Domenici, R Longo, A S de Carolis, C Frank, S Sagratell. Protective actions of 21-aminosteroids and MK-801 on hypoxia-induced electrophysiological changes in rat hippocampal slices. European journal of pharmacology vol 233 issue 2-3 1993 8467875 |
perfusion of slices with 50 microm of mk-801 or with 50-100 microm of u-78517f, but not with 100-200 microm of u-74500a, significantly (p < 0.01) increased the incidence of reappearance of the ca1 population spikes after reoxygenation in rat hippocampal slices subjected to a 45-min hypoxic period followed by a 45-min reoxygenation period. |
1993-05-11 |
2022-01-10 |
Not clear |
| L D Snell, B Tabakoff, P L Hoffma. Radioligand binding to the N-methyl-D-aspartate receptor/ionophore complex: alterations by ethanol in vitro and by chronic in vivo ethanol ingestion. Brain research vol 602 issue 1 1993 8448662 |
chronic in vivo ethanol ingestion by mice, that resulted in tolerance to and physical dependence on ethanol, produced an increased density of hippocampal [3h]mk-801 and [3h]l-glutamate binding sites, but not [3h]glycine or [3h]cgs 19755 binding sites. |
1993-04-12 |
2022-01-10 |
Not clear |
| Y Wada, H Hasegawa, M Nakamura, N Yamaguch. The NMDA receptor antagonist MK-801 has a dissociative effect on seizure activity of hippocampal-kindled cats. Pharmacology, biochemistry, and behavior vol 43 issue 4 1993 1475311 |
this study assessed the behavioral and electrographic effects of (+)-5-methyl-10,11-dihydro-5h-dibenzo-[a,d]cyclohepten-5,10-imine maleate (mk-801) (0.1 and 0.5 mg/kg, ip), a noncompetitive antagonist of the nmda receptors, in hippocampal (hip)-kindled cats. |
1993-02-01 |
2022-01-10 |
Not clear |
| R C Tasker, J T Coyle, J J Vorno. The regional vulnerability to hypoglycemia-induced neurotoxicity in organotypic hippocampal culture: protection by early tetrodotoxin or delayed MK-801. The Journal of neuroscience : the official journal of the Society for Neuroscience vol 12 issue 11 1992 1359034 |
the regional vulnerability to hypoglycemia-induced neurotoxicity in organotypic hippocampal culture: protection by early tetrodotoxin or delayed mk-801. |
1992-12-11 |
2022-01-10 |
Not clear |
| J U\\xc5\\x82as, L C Brunner, J W Geddes, W Choe, C W Cotma. N-methyl-D-aspartate receptor complex in the hippocampus of elderly, normal individuals and those with Alzheimer's disease. Neuroscience vol 49 issue 1 1992 1407551 |
the binding of [3h]mk-801 to channel-associated phencyclidine sites appeared to be most severely impaired in alzheimer's disease, especially at the anterior hippocampal level. |
1992-11-06 |
2022-01-10 |
Not clear |
| P S Whitton, C S Biggs, B R Pearce, L J Fowle. Regional effects of MK-801 on dopamine and its metabolites studied by in vivo microdialysis. Neuroscience letters vol 142 issue 1 1992 1407718 |
in contrast, hippocampal extracellular dopamine was increased in a dose-related manner by mk-801. |
1992-11-04 |
2022-01-10 |
Not clear |
| K Akiyama, Y Yoneda, K Ogita, T Itoh, A Daigen, I Sora, I Kohira, H Ujike, S Otsuk. Ionotropic excitatory amino acid receptors in discrete brain regions of kindled rats. Brain research vol 587 issue 1 1992 1326375 |
there was no significant change in [3h]mk-801 binding in the amygdala or hippocampus 7 days after the last hippocampal kindled seizure, or 28 days after the last amygdala kindled seizure. |
1992-10-22 |
2022-01-10 |
Not clear |
| H W Boddeke, K H Wiederhold, J M Palacio. Intracerebroventricular application of competitive and non-competitive NMDA antagonists induce similar effects upon rat hippocampal electroencephalogram and local cerebral glucose utilization. Brain research vol 585 issue 1-2 1992 1511299 |
the non-competitive antagonist, mk-801, induced dose-dependent suppression of rat hippocampal eeg energy both after intraperitoneal (i.p.) |
1992-09-29 |
2022-01-10 |
Not clear |
| Y Minabe, K Emor. Two types of neuroplasticities in the kindling phenomenon: effects of chronic MK-801 and methamphetamine. Brain research vol 585 issue 1-2 1992 1511307 |
using the low-frequency kindling technique, we studied the effects of chronic mk-801 and chronic methamphetamine (map) administration on hippocampal kindling seizure development. |
1992-09-29 |
2022-01-10 |
Not clear |
| J A Gorter, J P de Brui. Chronic neonatal MK-801 treatment results in an impairment of spatial learning in the adult rat. Brain research vol 580 issue 1-2 1992 1504791 |
chronic neonatal treatment with the non-competitive n-methyl-d-aspartate (nmda) receptor antagonist mk-801 from postnatal day 8 through 19 has been shown to affect hippocampal nmda receptor function of adult rats. |
1992-09-23 |
2022-01-10 |
Not clear |
| S Toki, E Tsukuda, M Nozawa, H Nonaka, M Yoshida, Y Matsud. The ES-242s, novel N-methyl-D-aspartate antagonists of microbial origin, interact with both the neurotransmitter recognition site and the ion channel domain. The Journal of biological chemistry vol 267 issue 21 1992 1378842 |
in a concentration range of 0.1-1.0 microm, es-242-1 was as potent as mk-801 in preventing glutamate-induced neurotoxicity in primary cultures of mouse hippocampal neurons. |
1992-08-26 |
2022-01-10 |
Not clear |
| J A Gorter, M Veerman, M Mirmira. Hippocampal neuronal responsiveness to NMDA agonists and antagonists in the adult rat neonatally treated with MK-801. Brain research vol 572 issue 1-2 1992 1351784 |
hippocampal neuronal responsiveness to nmda agonists and antagonists in the adult rat neonatally treated with mk-801. |
1992-07-24 |
2022-01-10 |
Not clear |
| G B Robinson, G D Ree. Effect of MK-801 on the induction and subsequent decay of long-term potentiation in the unanesthetized rabbit hippocampal dentate gyrus. Brain research vol 569 issue 1 1992 1611480 |
effect of mk-801 on the induction and subsequent decay of long-term potentiation in the unanesthetized rabbit hippocampal dentate gyrus. |
1992-07-24 |
2022-01-10 |
Not clear |
| J A Gorter, M Titulaer, N P Bos, E Huisma. Chronic neonatal MK-801 administration leads to a long-lasting increase in seizure sensitivity during the early stages of hippocampal kindling. Neuroscience letters vol 134 issue 1 1992 1840001 |
chronic neonatal mk-801 administration leads to a long-lasting increase in seizure sensitivity during the early stages of hippocampal kindling. |
1992-06-24 |
2022-01-10 |
Not clear |
| K Inoue, K Morimoto, K Sato, N Yamada, S Otsuk. Mechanisms in the development of limbic status epilepticus and hippocampal neuron loss: an experimental study in a model of status epilepticus induced by kindling-like electrical stimulation of the deep prepyriform cortex in rats. Acta medica Okayama vol 46 issue 2 1992 1533485 |
pretreatment with mk-801, a non-competitive n-methyl-d-aspartate (nmda) receptor antagonist (0.25 or 1 mg/kg), also prevented hippocampal cell loss, although it did not block se generation completely, which suggests dissociation of the mechanisms underlying the development of se and hippocampal damage. |
1992-06-04 |
2022-01-10 |
Not clear |