All Relations between (2R)-amino-5-phosphonovaleric acid (AP5) and hippocampus

Publication Sentence Publish Date Extraction Date Species
Beatriz Martínez Villayandre, Miguel Angel Paniagua, Arsenio Fernández-López, Pedro Calv. Effect of delta-aminolevulinic acid treatment on N-methyl-D-aspartate receptor at different ages in the rat brain. Brain research. vol 1061. issue 2. 2006-01-17. PMID:16229824. [3h]mk-801 binding was significantly decreased in most areas studied (cortex and hippocampus) at all ages in treated rats with respect to their controls. 2006-01-17 2023-08-12 rat
Yong Min Ahn, Myoung Suk Seo, Se Hyun Kim, Yeni Kim, Se Chang Yoon, Yong-Sung Juhnn, Yong Sik Ki. Increased phosphorylation of Ser473-Akt, Ser9-GSK-3beta and Ser133-CREB in the rat frontal cortex after MK-801 intraperitoneal injection. The international journal of neuropsychopharmacology. vol 8. issue 4. 2006-01-05. PMID:15877933. ser9-gsk-3beta phosphorylation was increased after injection of 1 mg/kg mk-801 in the rat frontal cortex but not in the hippocampus or cerebellum. 2006-01-05 2023-08-12 rat
L E Schechter, D L Smith, S Rosenzweig-Lipson, S J Sukoff, L A Dawson, K Marquis, D Jones, M Piesla, T Andree, S Nawoschik, J A Harder, M D Womack, J Buccafusco, A V Terry, B Hoebel, P Rada, M Kelly, M Abou-Gharbia, J E Barrett, W Childer. Lecozotan (SRA-333): a selective serotonin 1A receptor antagonist that enhances the stimulated release of glutamate and acetylcholine in the hippocampus and possesses cognitive-enhancing properties. The Journal of pharmacology and experimental therapeutics. vol 314. issue 3. 2005-10-21. PMID:15951399. learning deficits induced by the glutamatergic antagonist mk-801 [(-)-5-methyl-10,11-dihydro-5h-dibenzo[a,d]cyclohepten-5,10-imine maleate] (assessed by perceptually complex and visual spatial discrimination) and by specific cholinergic lesions of the hippocampus (assessed by visual spatial discrimination) were reversed by lecozotan (2 mg/kg i.m.) 2005-10-21 2023-08-12 monkey
M Mahiuddin Ahmed, Mohammad Arif, Toshiyuki Chikuma, Takeshi Kat. Pentylenetetrazol-induced seizures affect the levels of prolyl oligopeptidase, thimet oligopeptidase and glial proteins in rat brain regions, and attenuation by MK-801 pretreatment. Neurochemistry international. vol 47. issue 4. 2005-09-08. PMID:15985312. the activity of pop significantly decreased in the hippocampus at 30min and 3h, and in the frontal cortex at 3h after ptz treatment, and pretreatment with mk-801 recovered the activity in the cortex at 3h. 2005-09-08 2023-08-12 rat
M Mahiuddin Ahmed, Mohammad Arif, Toshiyuki Chikuma, Takeshi Kat. Pentylenetetrazol-induced seizures affect the levels of prolyl oligopeptidase, thimet oligopeptidase and glial proteins in rat brain regions, and attenuation by MK-801 pretreatment. Neurochemistry international. vol 47. issue 4. 2005-09-08. PMID:15985312. the activity of ep 24.15/16 significantly decreased in the hippocampus at 3h and 1 day, and in the cortex at 3h after the ptz administration, whereas pretreatment with mk-801 recovered the change of the activity. 2005-09-08 2023-08-12 rat
M Mahiuddin Ahmed, Mohammad Arif, Toshiyuki Chikuma, Takeshi Kat. Pentylenetetrazol-induced seizures affect the levels of prolyl oligopeptidase, thimet oligopeptidase and glial proteins in rat brain regions, and attenuation by MK-801 pretreatment. Neurochemistry international. vol 47. issue 4. 2005-09-08. PMID:15985312. the western blot analysis of ep 24.15 showed significant decrease of the protein level in the hippocampus 3h after the ptz treatment, whereas pretreatment with mk-801 recovered. 2005-09-08 2023-08-12 rat
Takao Hirai, Hideo Taniura, Yasuaki Goto, Keisuke Tamaki, Hirotaka Oikawa, Yuki Kambe, Masato Ogura, Yu Ohno, Takeshi Takarada, Yukio Yoned. Counteraction by repetitive daily exposure to static magnetism against sustained blockade of N-methyl-D-aspartate receptor channels in cultured rat hippocampal neurons. Journal of neuroscience research. vol 80. issue 4. 2005-07-25. PMID:15846781. in rat hippocampal neurons cultured with the antagonist for n-methyl-d-aspartate (nmda) receptors dizocilpine (mk-801) for 8 days in vitro (div), a significant decrease was seen in the expression of microtubule-associated protein-2 (map-2) as well as mrna for both brain-derived neurotrophic factor (bdnf) and growth-associated protein-43 (gap-43), in addition to decreased viability. 2005-07-25 2023-08-12 rat
Takao Hirai, Hideo Taniura, Yasuaki Goto, Keisuke Tamaki, Hirotaka Oikawa, Yuki Kambe, Masato Ogura, Yu Ohno, Takeshi Takarada, Yukio Yoned. Counteraction by repetitive daily exposure to static magnetism against sustained blockade of N-methyl-D-aspartate receptor channels in cultured rat hippocampal neurons. Journal of neuroscience research. vol 80. issue 4. 2005-07-25. PMID:15846781. these results suggest that repetitive magnetism may at least in part counteract the neurotoxicity of mk-801 through modulation of the expression of particular nmda receptor subunits in cultured rat hippocampal neurons. 2005-07-25 2023-08-12 rat
Kiyokazu Ogita, Hiroaki Okuda, Mami Watanabe, Reiko Nagashima, Chie Sugiyama, Yukio Yoned. In vivo treatment with the K+ channel blocker 4-aminopyridine protects against kainate-induced neuronal cell death through activation of NMDA receptors in murine hippocampus. Neuropharmacology. vol 48. issue 6. 2005-06-24. PMID:15829253. induced expression of c-fos in the hippocampal neuronal cell layer, which expression was completely abolished by the noncompetitive nmda receptor antagonist mk-801, thus indicating that the administration of 4-ap would activate nmda receptors in the hippocampal neurons. 2005-06-24 2023-08-12 mouse
Seikwan Oh, Chia-Yu Chang, Rodney C Baker, Ing K H. Phorbol ester differentiates the levels of [3H]MK-801 binding in rats lines selected for differential sensitivity to the hypnotic effects of ethanol. Neurochemical research. vol 30. issue 2. 2005-06-08. PMID:15895818. using a quantitative autoradiograph technique, it was demonstrated that [3h]mk-801 binding to the nmda receptor was highest in hippocampus in both has and las rats, but significant [3h]mk-801 binding was also detected in cortex, caudate-putamen, and thalamus of has and las rats. 2005-06-08 2023-08-12 rat
Toru Sasaki, Mie Yamaguchi, Shuji Kojim. Demonstration of hyperaccumulation of [18F]2-fluoro-2-deoxy-D-glucose under oxygen deprivation in living brain slices using bioradiography. Synapse (New York, N.Y.). vol 55. issue 4. 2005-05-26. PMID:15668912. glucose metabolism was also increased by the addition of glutamate and was attenuated by the n-methyl-d-aspartate (nmda) receptor antagonist mk-801 in the hippocampus and thalamus. 2005-05-26 2023-08-12 Not clear
Soyong Jang, Jong Hoon Ryu, Dong-Hyun Kim, Seikwan O. Changes of [3H]MK-801, [3H]muscimol and [3H]flunitrazepam binding in rat brain by the prolonged ventricular infusion of transformed ginsenosides. Neurochemical research. vol 29. issue 12. 2005-03-09. PMID:15672548. the levels of [3h]mk-801 binding were highly decreased in almost all regions of frontal cortex and hippocampus by ginsenoside rh2 and compound k. the levels of [3h]muscimol binding were elevated in part of frontal cortex and granule layer of cerebellum by the treatment of ginsenoside rh2 and compound k. however, the [3h]flunitrazepam binding was not modulated by any tested ginsenosides. 2005-03-09 2023-08-12 rat
Beatriz Martínez Villayandre, Miguel Angel Paniagua, Arsenio Fernández-López, Miguel Angel Chinchetru, Pedro Calv. Effect of vitamin E treatment on N-methyl-D-aspartate receptor at different ages in the rat brain. Brain research. vol 1028. issue 2. 2005-02-04. PMID:15527740. [(3)h] 5-methyl-10,11-dihydro-5h-dibenzo (a,d) cycloheptan-5,10-imine maleate (mk-801) binding was significantly increased in all areas studied (cortex and hippocampus) at all ages when rats received this treatment. 2005-02-04 2023-08-12 rat
Nahid K El-Bakri, Atiqul Islam, Shunwei Zhu, Adlan Elhassan, Abdul Mohammed, Bengt Winblad, Abdu Ade. Effects of estrogen and progesterone treatment on rat hippocampal NMDA receptors: relationship to Morris water maze performance. Journal of cellular and molecular medicine. vol 8. issue 4. 2005-01-31. PMID:15601582. our results showed a significant increase in [(3)h] mk-801 binding in the dentate gyrus, ca3 and ca4 areas of the hippocampus of ovariectomized compared to sham operated rats. 2005-01-31 2023-08-12 rat
Fabio Fumagalli, Raffaella Molteni, Francesco Bedogni, Massimo Gennarelli, Jorge Perez, Giorgio Racagni, Marco A Riv. Quetiapine regulates FGF-2 and BDNF expression in the hippocampus of animals treated with MK-801. Neuroreport. vol 15. issue 13. 2005-01-13. PMID:15486491. quetiapine regulates fgf-2 and bdnf expression in the hippocampus of animals treated with mk-801. 2005-01-13 2023-08-12 rat
T Valente, M-I Domínguez, A Bellmann, L Journot, I Ferrer, C Auladel. Zac1 is up-regulated in neural cells of the limbic system of mouse brain following seizures that provoke strong cell activation. Neuroscience. vol 128. issue 2. 2004-12-09. PMID:15350644. pre-treatment with mk-801, an antagonist of the nmda receptors, fully blocks the effect of ka in the hippocampus, whereas it only attenuates ka-induced zac1 up-regulation in the other areas of the limbic system. 2004-12-09 2023-08-12 mouse
Taketo Isao, Kazufumi Akiyam. Effect of acute and chronic treatment with methamphetamine on mRNA expression of synaptotagmin IV and 25 KDa-synaptic-associated protein in the rat brain. Psychiatry and clinical neurosciences. vol 58. issue 4. 2004-12-07. PMID:15298655. pretreatment with 0.5 mg/kg sch23390, but not 0.5 mg/kg mk-801, significantly attenuated the increased snap25a mrna levels induced by acute meth administration in the striatum and the dentate gyrus of the hippocampus. 2004-12-07 2023-08-12 rat
Chiara Adembri, Annalisa Bechi, Elena Meli, Elena Gramigni, Luna Venturi, Flavio Moroni, A Raffaele De Gaudio, Domenico E Pellegrini-Giampietr. Erythropoietin attenuates post-traumatic injury in organotypic hippocampal slices. Journal of neurotrauma. vol 21. issue 8. 2004-12-02. PMID:15319009. addition of rhepo (1-100 ui/ml) or of the nmda antagonist mk-801 (30 microm) immediately after the traumatic injury reduced hippocampal damage by approximately 30% when observed 24 h later. 2004-12-02 2023-08-12 human
V D Gerasimov, D P Artemenko, O A Krishta. Therapeutic time window for the neuroprotective action of MK-801 after decapitation ischemia: hippocampal slice data. Brain research. vol 1017. issue 1-2. 2004-10-04. PMID:15261104. therapeutic time window for the neuroprotective action of mk-801 after decapitation ischemia: hippocampal slice data. 2004-10-04 2023-08-12 Not clear
V D Gerasimov, D P Artemenko, O A Krishta. Therapeutic time window for the neuroprotective action of MK-801 after decapitation ischemia: hippocampal slice data. Brain research. vol 1017. issue 1-2. 2004-10-04. PMID:15261104. neuroprotective action of mk-801 administrated pre- and postischemically, in vivo or in vitro, respectively, was studied on hippocampal slices using decapitation ischemia model. 2004-10-04 2023-08-12 Not clear