All Relations between (2R)-amino-5-phosphonovaleric acid (AP5) and hippocampus

Publication Sentence Publish Date Extraction Date Species
Ming-Heng Hsiung, Wan-Ling Huang, Li-Yu Kan, Li-Hsien Chen, Sherry Shu-Jung H. The facilitating effect of MK-801 on inhibitory avoidance memory via mTOR signaling in the mouse hippocampus. Behavioural brain research. vol 389. 2021-05-06. PMID:32348869. these results indicate that hippocampal mtor signaling mediates the facilitating effect of mk-801 on memory consolidation of the inhibitory avoidance task. 2021-05-06 2023-08-13 mouse
G Unal, H Bekci, A Cumaoglu, M B Yerer, F Ariciogl. Alpha 7 nicotinic receptor agonist and positive allosteric modulators improved social and molecular deficits of MK-801 model of schizophrenia in rats. Pharmacology, biochemistry, and behavior. vol 193. 2021-01-21. PMID:32220620. besides, mk-801 decreased the α7 nachr, p-gsk-3β/gsk-3β expressions in the hippocampus. 2021-01-21 2023-08-13 rat
Harish M Kawade, Chandrashekhar D Borkar, Ashwini S Shambharkar, Omprakash Singh, Praful S Singru, Nishikant K Subhedar, Dadasaheb M Kokar. Intracellular mechanisms and behavioral changes in mouse model of attention deficit hyperactivity disorder: Importance of age-specific NMDA receptor blockade. Pharmacology, biochemistry, and behavior. vol 188. 2020-12-31. PMID:31756355. a significant increase in caspase-3 expression was noted in the prefrontal cortex (pfc) and hippocampus, whereas increased pakt was noticed only in the hippocampus, following a single injection of mk-801 at pnd 7. 2020-12-31 2023-08-13 mouse
Ane Murueta-Goyena, Naiara Ortuzar, José Vicente Lafuente, Harkaitz Bengoetxe. Enriched Environment Reverts Somatostatin Interneuron Loss in MK-801 Model of Schizophrenia. Molecular neurobiology. vol 57. issue 1. 2020-11-19. PMID:31506899. we observed that early-life mk-801 treatment significantly decreased the number of sst+ interneurons in the medial prefrontal cortex (mpfc) and the hippocampus (hpc) of adult long evans rats. 2020-11-19 2023-08-13 rat
Guangdong Chen, Xiaodong Lin, Gongying Li, Diego Jiang, Zhiruo Lib, Ronghuan Jiang, Chuanjun Zhu. Risperidone reverses the spatial object recognition impairment and hippocampal BDNF-TrkB signalling system alterations induced by acute MK-801 treatment. Biomedical reports. vol 6. issue 3. 2020-10-01. PMID:28451387. risperidone reverses the spatial object recognition impairment and hippocampal bdnf-trkb signalling system alterations induced by acute mk-801 treatment. 2020-10-01 2023-08-13 rat
Guangdong Chen, Xiaodong Lin, Gongying Li, Diego Jiang, Zhiruo Lib, Ronghuan Jiang, Chuanjun Zhu. Risperidone reverses the spatial object recognition impairment and hippocampal BDNF-TrkB signalling system alterations induced by acute MK-801 treatment. Biomedical reports. vol 6. issue 3. 2020-10-01. PMID:28451387. the aim of the present study was to investigate the effects of a commonly-used atypical antipsychotic, risperidone, on alterations in spatial learning and in the hippocampal brain-derived neurotrophic factor (bdnf)-tyrosine receptor kinase b (trkb) signalling system caused by acute dizocilpine maleate (mk-801) treatment. 2020-10-01 2023-08-13 rat
Guangdong Chen, Xiaodong Lin, Gongying Li, Diego Jiang, Zhiruo Lib, Ronghuan Jiang, Chuanjun Zhu. Risperidone reverses the spatial object recognition impairment and hippocampal BDNF-TrkB signalling system alterations induced by acute MK-801 treatment. Biomedical reports. vol 6. issue 3. 2020-10-01. PMID:28451387. of note, we found that risperidone successfully reversed the deleterious effects of mk-801 on spatial object recognition and upregulated the hippocampal bdnf-trkb signalling system. 2020-10-01 2023-08-13 rat
Dongsheng Zhou, Dan Lv, Zhen Wang, Yanhua Zhang, Zhongming Chen, Chuang Wan. GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:29695955. glyx-13 ameliorates schizophrenia-like phenotype induced by mk-801 in mice: role of hippocampal nr2b and disc1. 2020-10-01 2023-08-13 mouse
Yuanyi Xie, Xu-Feng Huan. Commentary: GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1. Frontiers in molecular neuroscience. vol 11. 2020-10-01. PMID:30233316. commentary: glyx-13 ameliorates schizophrenia-like phenotype induced by mk-801 in mice: role of hippocampal nr2b and disc1. 2020-10-01 2023-08-13 mouse
Wenjuan Yu, Min Zhu, Hongwei Fang, Jie Zhou, Le Ye, Wenyu Bian, Yuan Wang, Hui Zhu, Jie Xiao, Hao Zhu, Huafang L. Risperidone Reverses the Downregulation of BDNF in Hippocampal Neurons and MK801-Induced Cognitive Impairment in Rats. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31396062. our previous study showed that brain-derived neurotrophic factor (bdnf) signaling was upregulated in cultured hippocampal astrocytes in response to mk-801. 2020-10-01 2023-08-13 rat
Wenjuan Yu, Min Zhu, Hongwei Fang, Jie Zhou, Le Ye, Wenyu Bian, Yuan Wang, Hui Zhu, Jie Xiao, Hao Zhu, Huafang L. Risperidone Reverses the Downregulation of BDNF in Hippocampal Neurons and MK801-Induced Cognitive Impairment in Rats. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31396062. to address this issue, we examined bdnf expression in the hippocampus of rats that received repeated injections of mk-801 (0.5 mg/kg body weight for 6 days) and in primary cultured hippocampal neurons incubated with 20 μm mk-801 for 24 h. bdnf expression and cognitive function were also evaluated in rats receiving intraperitoneal injections of risperidone (1 mg/kg body weight) once daily for 7 days and in hippocampal neurons incubated with 10 μm risperidone following mk801 treatment. 2020-10-01 2023-08-13 rat
Wenjuan Yu, Min Zhu, Hongwei Fang, Jie Zhou, Le Ye, Wenyu Bian, Yuan Wang, Hui Zhu, Jie Xiao, Hao Zhu, Huafang L. Risperidone Reverses the Downregulation of BDNF in Hippocampal Neurons and MK801-Induced Cognitive Impairment in Rats. Frontiers in behavioral neuroscience. vol 13. 2020-10-01. PMID:31396062. mk-801 treatment decreased bdnf expression in the rat hippocampus as well as the expression and secretion of bdnf in hippocampal neurons 2020-10-01 2023-08-13 rat
Xiao Liu, Jitao Li, Chunmei Guo, Hongli Wang, Yaxin Sun, Han Wang, Yun-Ai Su, Keqing Li, Tianmei S. Olanzapine Reverses MK-801-Induced Cognitive Deficits and Region-Specific Alterations of NMDA Receptor Subunits. Frontiers in behavioral neuroscience. vol 11. 2020-09-30. PMID:29375333. in this study, adopting repeated mk-801 treatment as an animal model of schizophrenia, we investigated whether antipsychotic drugs, olanzapine and haloperidol, can reverse mk-801-induced cognitive deficits and how the reversal processes recruited proteins involved in glutamate neurotransmission in rat medial prefrontal cortex (mpfc) and hippocampus. 2020-09-30 2023-08-13 rat
Libor Uttl, Tomas Petrasek, Hilal Sengul, Marketa Svojanovska, Veronika Lobellova, Karel Vales, Dominika Radostova, Grygoriy Tsenov, Hana Kubova, Anna Mikulecka, Jan Svoboda, Ales Stuchli. Chronic MK-801 Application in Adolescence and Early Adulthood: A Spatial Working Memory Deficit in Adult Long-Evans Rats But No Changes in the Hippocampal NMDA Receptor Subunits. Frontiers in pharmacology. vol 9. 2020-09-30. PMID:29487522. chronic mk-801 application in adolescence and early adulthood: a spatial working memory deficit in adult long-evans rats but no changes in the hippocampal nmda receptor subunits. 2020-09-30 2023-08-13 rat
Juan Ding, Yu Shao, Hui-Hui Zhou, Quan-Rui Ma, Yi-Wei Zhang, Yin-Xiu Ding, Yu-Qing He, Juan Li. Effect of NMDA on proliferation and apoptosis in hippocampal neural stem cells treated with MK-801. Experimental and therapeutic medicine. vol 16. issue 2. 2020-09-30. PMID:30116364. effect of nmda on proliferation and apoptosis in hippocampal neural stem cells treated with mk-801. 2020-09-30 2023-08-13 Not clear
Konstantin V. Sudakov, Pavel E. Umriukhin, Kirill S. Rayevsk. Delta-sleep inducing peptide and neuronal activity after glutamate microiontophoresis: the role of NMDA-receptors. Pathophysiology : the official journal of the International Society for Pathophysiology. vol 11. issue 2. 2020-09-29. PMID:15364118. the influence of microiontophoretic application of delta-sleep inducing peptide (dsip) on a neuronal activity of sensorimotor brain cortex, dorsal hippocampus, ventral anterior thalamic nucleus and lateral hypothalamus was studied under the effects of glutamate and mk-801, a n-methyl-d-aspartate non-competitive antagonist, on male wistar rats. 2020-09-29 2023-08-12 rat
Libor Uttl, Tomas Petrasek, Hilal Sengul, Marketa Svojanovska, Veronika Lobellova, Karel Vales, Dominika Radostova, Grygoriy Tsenov, Hana Kubova, Anna Mikulecka, Jan Svoboda, Ales Stuchli. Corrigendum: Chronic MK-801 Application in Adolescence and Early Adulthood: A Spatial Working Memory Deficit in Adult Long-Evans Rats But No Changes in the Hippocampal NMDA Receptor Subunits. Frontiers in pharmacology. vol 9. 2020-09-29. PMID:29951000. corrigendum: chronic mk-801 application in adolescence and early adulthood: a spatial working memory deficit in adult long-evans rats but no changes in the hippocampal nmda receptor subunits. 2020-09-29 2023-08-13 rat
Ximena López Hill, Analía Richeri, Ronald McGregor, Alejo Acuña, Cecilia Scorz. Neuro-behavioral effects after systemic administration of MK-801 and disinhibition of the anterior thalamic nucleus in rats: Potential relevance in schizophrenia. Brain research. vol 1718. 2020-09-29. PMID:31071305. consistent with the possibility that these responses were mediated by thalamic disinhibition, we examined the participation of cortical and hippocampal areas innervated by atn in the responses elicited by the systemic administration of mk-801 (0.2 mg/kg) and compared them to the effects produced by the microinjection of a subconvulsive dose of bicuculline (gaba 2020-09-29 2023-08-13 rat
Julia C Bartsch, Joachim Beh. Noncanonical, Dopamine-Dependent Long-Term Potentiation at Hippocampal Output Synapses in a Rodent Model of First-Episode Psychosis. Frontiers in molecular neuroscience. vol 13. 2020-09-28. PMID:32317931. here, we used a single systemic application of the noncompetitive glutamatergic n-methyl-d-aspartate receptor (nmdar) antagonist mk-801 to model first-episode psychosis in rats and studied long-term potentiation (ltp) in subicular regular-firing cells in acute hippocampal slices. 2020-09-28 2023-08-13 rat
Mahdiyeh Faatehi, Mohsen Basiri, Akram Nezhadi, Mohammad Shabani, Yaser Masoumi-Ardakani, Zahra Soltani, Masoumeh Nozar. Early enriched environment prevents cognitive impairment in an animal model of schizophrenia induced by MK-801: Role of hippocampal BDNF. Brain research. vol 1711. 2020-08-04. PMID:30677409. early enriched environment prevents cognitive impairment in an animal model of schizophrenia induced by mk-801: role of hippocampal bdnf. 2020-08-04 2023-08-13 rat