Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Ximena López Hill, Analía Richeri, Cecilia Scorz. Measure of anxiety-related behaviors and hippocampal BDNF levels associated to the amnesic effect induced by MK-801 evaluated in the modified elevated plus-maze in rats. Physiology & behavior. vol 147. 2016-02-23. PMID:25992477. |
measure of anxiety-related behaviors and hippocampal bdnf levels associated to the amnesic effect induced by mk-801 evaluated in the modified elevated plus-maze in rats. |
2016-02-23 |
2023-08-13 |
rat |
Ximena López Hill, Analía Richeri, Cecilia Scorz. Measure of anxiety-related behaviors and hippocampal BDNF levels associated to the amnesic effect induced by MK-801 evaluated in the modified elevated plus-maze in rats. Physiology & behavior. vol 147. 2016-02-23. PMID:25992477. |
therefore, we investigated if changes in anxiety-related behaviors and hippocampal bdnf levels are related with the amnesic effect induced by mk-801 in the mepm.transfer latency (tl) as an index of spatial memory in the mepm was used. |
2016-02-23 |
2023-08-13 |
rat |
Morgana Moretti, Josiane Budni, Andiara Espíndola Freitas, Vivian Binder Neis, Camille Mertins Ribeiro, Grasiela de Oliveira Balen, Débora Kurrle Rieger, Rodrigo Bainy Leal, Ana Lúcia S Rodrigue. TNF-α-induced depressive-like phenotype and p38(MAPK) activation are abolished by ascorbic acid treatment. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 6. 2016-02-16. PMID:25836357. |
additionally, we examined the effects of combined administration of ascorbic acid and antidepressants, mk-801 and 7-nitroindazole in mice exposed or not to tnf-α and the capacity of tnf-α and ascorbic acid to modulate hippocampal and cerebrocortical phosphorylation of extracellular signal-regulated kinase (erk), p38(mapk) and c-jun n-terminal kinase (jnk). |
2016-02-16 |
2023-08-13 |
mouse |
Kevin Blot, Shin-Ichi Kimura, Jing Bai, Anne Kemp, Denise Manahan-Vaughan, Bruno Giros, Eleni Tzavara, Satoru Otan. Modulation of hippocampus-prefrontal cortex synaptic transmission and disruption of executive cognitive functions by MK-801. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 5. 2016-01-19. PMID:24304584. |
in the present study, we tested in rats the effect of mk-801 on ventral hippocampus (hpc)-medial prefrontal cortex (mpfc) synaptic transmission and the performance in 2 cognitive tasks. |
2016-01-19 |
2023-08-12 |
rat |
Julia C Bartsch, Pawel Fidzinski, Jojanneke H J Huck, Heide Hörtnagl, Richard Kovács, Agustin Liotta, Josef Priller, Christian Wozny, Joachim Beh. Enhanced dopamine-dependent hippocampal plasticity after single MK-801 application. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 4. 2016-01-05. PMID:25315194. |
enhanced dopamine-dependent hippocampal plasticity after single mk-801 application. |
2016-01-05 |
2023-08-13 |
Not clear |
Ataç Sönmez, Oya Sayın, Seren Gülşen Gürgen, Meryem Çalişi. Neuroprotective effects of MK-801 against traumatic brain injury in immature rats. Neuroscience letters. vol 597. 2015-10-19. PMID:25943283. |
we aimed to investigate the effect of mk-801, a competitive nmda receptor antagonist, on hippocampal damage and behavioral deficits on 10-day-old rat pups subjected to contusion injury. |
2015-10-19 |
2023-08-13 |
rat |
Ataç Sönmez, Oya Sayın, Seren Gülşen Gürgen, Meryem Çalişi. Neuroprotective effects of MK-801 against traumatic brain injury in immature rats. Neuroscience letters. vol 597. 2015-10-19. PMID:25943283. |
the aims of the present study were to determine: (i) the short term effects of mk-801 on hippocampal bdnf, ngf and nmda receptor immunoreactivity and neuron density in hippocampus (ii) long term effects of mk-801 on cognitive dysfunction following tbi in the immature rats. |
2015-10-19 |
2023-08-13 |
rat |
Ataç Sönmez, Oya Sayın, Seren Gülşen Gürgen, Meryem Çalişi. Neuroprotective effects of MK-801 against traumatic brain injury in immature rats. Neuroscience letters. vol 597. 2015-10-19. PMID:25943283. |
additionally, treatment with mk-801 ameliorated anxiety and hippocampus dependent memory of animals subjected to trauma. |
2015-10-19 |
2023-08-13 |
rat |
Ataç Sönmez, Oya Sayın, Seren Gülşen Gürgen, Meryem Çalişi. Neuroprotective effects of MK-801 against traumatic brain injury in immature rats. Neuroscience letters. vol 597. 2015-10-19. PMID:25943283. |
these results show that acute treatment of mk-801 has a neuroprotective role against trauma induced hippocampal neuron loss and associated cognitive impairment in immature rats. |
2015-10-19 |
2023-08-13 |
rat |
Chen Zhang, Yiru Fang, Lin X. Glutamate receptor 1 phosphorylation at serine 845 contributes to the therapeutic effect of olanzapine on schizophrenia-like cognitive impairments. Schizophrenia research. vol 159. issue 2-3. 2015-08-19. PMID:25219486. |
after mk-801 application, the hippocampal ltp was profoundly impaired. |
2015-08-19 |
2023-08-13 |
rat |
Magalí C Cercato, Natalia Colettis, Marina Snitcofsky, Alejandra I Aguirre, Edgar E Kornisiuk, María V Baez, Diana A Jerusalinsk. Hippocampal NMDA receptors and the previous experience effect on memory. Journal of physiology, Paris. vol 108. issue 4-6. 2015-07-15. PMID:25132342. |
adult rats that explored twice an open field (of) before a weak though overthreshold training in inhibitory avoidance (ia), expressed ia long-term memory in spite of the hippocampal administration of mk-801, which currently leads to amnesia. |
2015-07-15 |
2023-08-13 |
rat |
Qianfa Long, Cairui Fan, Wang Kai, Qiang Luo, Weichuan Xin, Ping Wang, Ansheng Wang, Zhanyao Wang, Rui Han, Zhou Fei, Bensheng Qiu, Weiping Li. Hypoxia inducible factor-1α expression is associated with hippocampal apoptosis during epileptogenesis. Brain research. vol 1590. 2015-07-09. PMID:25242614. |
the results showed that the administration of mk-801 significantly reduced (p<0.05) hif-1α expression and hippocampal apoptosis during epileptogenesis in comparison with the positive control. |
2015-07-09 |
2023-08-13 |
rat |
Irina Korshunova, Michelle D Gjørlund, Sylwia Owczarek, Anders V Petersen, Jean-François Perrier, Casper René Gøtzsche, Vladimir Berezi. A neuroligin-1-derived peptide stimulates phosphorylation of the NMDA receptor NR1 subunit and rescues MK-801-induced decrease in long-term potentiation and memory impairment. Pharmacology research & perspectives. vol 3. issue 2. 2015-06-03. PMID:26038702. |
subsequently, we investigated effects of neurolide-1 on long-term potentiation (ltp) induction in hippocampal slices compromised by nmda receptor inhibitor mk-801. |
2015-06-03 |
2023-08-13 |
Not clear |
Irina Korshunova, Michelle D Gjørlund, Sylwia Owczarek, Anders V Petersen, Jean-François Perrier, Casper René Gøtzsche, Vladimir Berezi. A neuroligin-1-derived peptide stimulates phosphorylation of the NMDA receptor NR1 subunit and rescues MK-801-induced decrease in long-term potentiation and memory impairment. Pharmacology research & perspectives. vol 3. issue 2. 2015-06-03. PMID:26038702. |
we found that subcutaneous neurolide-1 administration, restored hippocampal ltp compromised by nmda receptor inhibitor mk-801. |
2015-06-03 |
2023-08-13 |
Not clear |
Hui Liu, Li-Min Wen, Hui Qiao, Shu-Cheng A. [Modulation of hippocampal glutamate and NMDA/AMPA receptor by homocysteine in chronic unpredictable mild stress-induced rat depression]. Sheng li xue bao : [Acta physiologica Sinica]. vol 65. issue 1. 2015-05-16. PMID:23426515. |
intrahippocampal injections of mk-801 effectively improved the depression-like behaviors induced by cums and hcy, and attenuated the elevation of glu content induced by hcy in hippocampus, whereas nbqx could not improve the depression-like behaviors, but also decreased the glu content induced by hcy remarkably. |
2015-05-16 |
2023-08-12 |
rat |
Yan He, Sheng-Ya Zeng, Shi-Wen Zhou, Gui-Sheng Qian, Kang Peng, Zhi-Xian Mo, Ji-Yin Zho. Effects of rhynchophylline on GluN1 and GluN2B expressions in primary cultured hippocampal neurons. Fitoterapia. vol 98. 2015-05-13. PMID:25110195. |
after 48 h incubation, a lower concentration of rhynchophylline (lower than 400 μmol/l) and mk-801 (lower than 200 μmol/l) have no toxicity on neonatal hippocampal neurons. |
2015-05-13 |
2023-08-13 |
rat |
Claudia Alva-Sanchez, Adair Rodriguez, Ivan Villanueva, Brenda Anguiano, Carmen Aceves, Jorge Pacheco-Rosad. The NMDA receptor antagonist MK-801 abolishes the increase in both p53 and Bax/Bcl2 index induced by adult-onset hypothyroidism in rat. Acta neurobiologiae experimentalis. vol 74. issue 1. 2015-04-06. PMID:24718050. |
in this work we measured the expression of specific proteins that control cell proliferation (cycline-d1), cell arrest (p21), damage (p53) or apoptosis (bax and bcl2) in the hippocampus of hypothyroid rats treated with the nmda receptor (nmdar) blocker mk-801 during the induction of hypothyroidism. |
2015-04-06 |
2023-08-13 |
rat |
Qing Wang, Jin Li, Xiaobo Wei, Jinchi Liao, Yunqi Xu, Tingting Lu, Bing Qin, Junqiang Xie, Chao Deng, Xufeng Huan. Alterations of NMDA receptor binding in various brain regions among 6-hydroxydopamine-induced Parkinsonian rats. The International journal of neuroscience. vol 124. issue 6. 2015-01-12. PMID:24102195. |
in the 6-ohda-induced parkinsonian rat model, nigrostriatal dopaminergic neuron loss significantly mediated the decreased [(3)h] mk-801 binding, predominantly in the hippocampus (-22.4%, p < 0.001), caudate putamen (-14.1%, p < 0.01), accumbens nucleus (-13.8%, p < 0.05), cingulate cortex (-13.4%, p < 0.001), posteromedial cortical amygdala (-14.5%, p < 0.01) and piriform cortex (-9%, p < 0.05) compared to the controls, while there was a profound reduction of tyrosine hydroxylase (th) immunohistochemistry in the substantia nigra pars compacta. |
2015-01-12 |
2023-08-12 |
rat |
Kang Li, Hengchuan Jia, Xiaojun She, Bo Cui, Na Zhang, Xuewei Chen, Chuanxiang Xu, Gaihong An, Qiang M. Role of NMDA receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24685355. |
mk-801 decreased the hyperphosphorylation of tau at ser202 and ser396 sites in the hippocampus and pfc. |
2014-12-22 |
2023-08-12 |
rat |
Kang Li, Hengchuan Jia, Xiaojun She, Bo Cui, Na Zhang, Xuewei Chen, Chuanxiang Xu, Gaihong An, Qiang M. Role of NMDA receptors in noise-induced tau hyperphosphorylation in rat hippocampus and prefrontal cortex. Journal of the neurological sciences. vol 340. issue 1-2. 2014-12-22. PMID:24685355. |
this suggests that mk-801 protects against chronic-noise-induced tau hyperphosphorylation in the hippocampus and pfc. |
2014-12-22 |
2023-08-12 |
rat |