All Relations between (2R)-amino-5-phosphonovaleric acid (AP5) and hippocampus

Publication Sentence Publish Date Extraction Date Species
Takashi Uehara, Tomiki Sumiyoshi, Dan Rujescu, Just Genius, Tadasu Matsuoka, Ichiro Takasaki, Hiroko Itoh, Masayoshi Kurach. Neonatal exposure to MK-801 reduces mRNA expression of mGlu3 receptors in the medial prefrontal cortex of adolescent rats. Synapse (New York, N.Y.). vol 68. issue 5. 2014-11-07. PMID:24549941. the effect of 4-day (postnatal day; pd 7-10) administration of mk-801, a selective nmda-r antagonist, on gene expression in the medial prefrontal cortex (mpfc), hippocampus, and amygdala was evaluated using quantitative polymerase chain reaction methods. 2014-11-07 2023-08-12 rat
G Flores, O Ibañez-Sandoval, A B Silva-Gómez, I Camacho-Abrego, A Rodríguez-Moreno, J C Morales-Medin. Neonatal olfactory bulbectomy enhances locomotor activity, exploratory behavior and binding of NMDA receptors in pre-pubertal rats. Neuroscience. vol 259. 2014-09-11. PMID:24295633. interestingly, pre-pubertal rats showed a significant increase in the [(125)i]mk-801 binding in the piriform cortex, dorsal hippocampus, inner and outer layers of the frontal cortex and outer layer of the cingulate cortex. 2014-09-11 2023-08-12 rat
Jin Woo Chung, Jin-Hee Seo, Sang-Bin Baek, Chang-Ju Kim, Tae-Woon Ki. Treadmill exercise inhibits hippocampal apoptosis through enhancing N-methyl-D-aspartate receptor expression in the MK-801-induced schizophrenic mice. Journal of exercise rehabilitation. vol 10. issue 4. 2014-09-11. PMID:25210696. in the present results, repeated injection of the nmda receptor antagonist mk-801 reduced expression of nmda receptor in hippocampal ca2-3 regions. 2014-09-11 2023-08-13 mouse
Jin Woo Chung, Jin-Hee Seo, Sang-Bin Baek, Chang-Ju Kim, Tae-Woon Ki. Treadmill exercise inhibits hippocampal apoptosis through enhancing N-methyl-D-aspartate receptor expression in the MK-801-induced schizophrenic mice. Journal of exercise rehabilitation. vol 10. issue 4. 2014-09-11. PMID:25210696. mk-801 injection increased casapse-3 expression and enhanced cytochrome c release in the hippocampus. 2014-09-11 2023-08-13 mouse
Daniel R Thomases, Daryn K Cass, Jacqueline D Meyer, Adriana Caballero, Kuei Y Tsen. Early adolescent MK-801 exposure impairs the maturation of ventral hippocampal control of basolateral amygdala drive in the adult prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 27. 2014-08-29. PMID:24990926. early adolescent mk-801 exposure impairs the maturation of ventral hippocampal control of basolateral amygdala drive in the adult prefrontal cortex. 2014-08-29 2023-08-13 rat
Walter E Babiec, Ryan Guglietta, Shekib A Jami, Wade Morishita, Robert C Malenka, Thomas J O'Del. Ionotropic NMDA receptor signaling is required for the induction of long-term depression in the mouse hippocampal CA1 region. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 15. 2014-06-16. PMID:24719106. we find that the induction of ltd in the adult hippocampus is highly sensitive to extracellular ca(2+) levels and that mk-801 blocks nmdar-dependent ltd in the hippocampus of both adult and immature mice. 2014-06-16 2023-08-13 mouse
Se Jin Park, Se Jin Jeon, Ike C Dela Peña, Hyung Eun Lee, Dong Hyun Kim, Jong Min Kim, Young Woo Lee, Jun Man Jung, Bum Young Shin, Seungheon Lee, Jae Hoon Cheong, Chan Young Shin, Dae Sik Jang, Jong Hoon Ry. Prunella vulgaris attenuates prepulse inhibition deficit and attention disruption induced by MK-801 in mice. Phytotherapy research : PTR. vol 27. issue 12. 2014-06-05. PMID:23348874. we also found that eepv attenuated the increased phosphorylated extracellular signal-regulated kinase, phosphorylated protein kinase b, or phospho-glycogen synthase kinase 3-β levels induced by mk-801 in the cortex but not in the hippocampus. 2014-06-05 2023-08-12 mouse
Dai Han, Li Xu, Honglei Xiao, Georgia C Prado Schmidt, Shenxun Sh. Dizocilpine reduces head diameter of dendritic spines in the hippocampus of adolescent rats. Psychiatry research. vol 210. issue 1. 2014-05-30. PMID:23747234. as a result, mk-801 impaired spatial memory in the adolescent rats, as well as reduced the proportion of mushroom spines and increased the proportion of stubby spines in hippocampus. 2014-05-30 2023-08-12 rat
Dai Han, Li Xu, Honglei Xiao, Georgia C Prado Schmidt, Shenxun Sh. Dizocilpine reduces head diameter of dendritic spines in the hippocampus of adolescent rats. Psychiatry research. vol 210. issue 1. 2014-05-30. PMID:23747234. mk-801 also reduced the expression levels of rac1 and cdc42 mrna and upregulated rhoa mrna in hippocampus. 2014-05-30 2023-08-12 rat
Dai Han, Li Xu, Honglei Xiao, Georgia C Prado Schmidt, Shenxun Sh. Dizocilpine reduces head diameter of dendritic spines in the hippocampus of adolescent rats. Psychiatry research. vol 210. issue 1. 2014-05-30. PMID:23747234. these results imply that subchronic mk-801 administration during adolescence might disturb the expression of rhoa, rac1 and cdc42 mrna, and then lead to the decay of the spines in hippocampus, which could be involved in cognitive impairments in schizophrenia. 2014-05-30 2023-08-12 rat
Brian Lord, Cindy Wintmolders, Xavier Langlois, Leslie Nguyen, Tim Lovenberg, Pascal Bonaventur. Comparison of the ex vivo receptor occupancy profile of ketamine to several NMDA receptor antagonists in mouse hippocampus. European journal of pharmacology. vol 715. issue 1-3. 2014-04-14. PMID:23872376. the receptor occupancy profiles of several nmda receptor antagonists (30 mg/kg, s.c.) were compared in mouse hippocampus by ex vivo autoradiography using [(3)h]mk-801, a non-selective nmda channel blocker, and [(3)h]ifenprodil a selective glun2b antagonist. 2014-04-14 2023-08-12 mouse
Brian Lord, Cindy Wintmolders, Xavier Langlois, Leslie Nguyen, Tim Lovenberg, Pascal Bonaventur. Comparison of the ex vivo receptor occupancy profile of ketamine to several NMDA receptor antagonists in mouse hippocampus. European journal of pharmacology. vol 715. issue 1-3. 2014-04-14. PMID:23872376. subcutaneous administration of ketamine ((rs)-2-(2-chlorophenyl)-2-(methylamino)cyclohexanone) and memantine (3,5-dimethyladamantan-1-amine) inhibited [(3)h]mk-801 but not [(3)h]ifenprodil binding in mouse hippocampus. 2014-04-14 2023-08-12 mouse
Stěpán Kubík, Helena Buchtová, Karel Valeš, Aleš Stuchlí. MK-801 Impairs Cognitive Coordination on a Rotating Arena (Carousel) and Contextual Specificity of Hippocampal Immediate-Early Gene Expression in a Rat Model of Psychosis. Frontiers in behavioral neuroscience. vol 8. 2014-03-24. PMID:24659959. mk-801 impairs cognitive coordination on a rotating arena (carousel) and contextual specificity of hippocampal immediate-early gene expression in a rat model of psychosis. 2014-03-24 2023-08-12 rat
Stěpán Kubík, Helena Buchtová, Karel Valeš, Aleš Stuchlí. MK-801 Impairs Cognitive Coordination on a Rotating Arena (Carousel) and Contextual Specificity of Hippocampal Immediate-Early Gene Expression in a Rat Model of Psychosis. Frontiers in behavioral neuroscience. vol 8. 2014-03-24. PMID:24659959. we also examined if the same dose of mk-801 alters patterns of immediate-early gene (ieg) expression in the hippocampus. 2014-03-24 2023-08-12 rat
Liya Sun, Juan Li, Kejun Zhou, Ming Zhang, Jinglei Yang, Yang Li, Baohu Ji, Zhao Zhang, Hui Zhu, Lun Yang, Guang He, Linghan Gao, Zhiyun Wei, Kejian Wang, Xue Han, Weiqing Liu, Liwen Tan, Yihua Yu, Lin He, Chunling Wa. Metabolomic analysis reveals metabolic disturbance in the cortex and hippocampus of subchronic MK-801 treated rats. PloS one. vol 8. issue 4. 2013-10-22. PMID:23577129. metabolomic analysis reveals metabolic disturbance in the cortex and hippocampus of subchronic mk-801 treated rats. 2013-10-22 2023-08-12 rat
T Kiss, J Feng, W E Hoffmann, C L Shaffer, M Hajó. Rhythmic theta and delta activity of cortical and hippocampal neuronal networks in genetically or pharmacologically induced N-methyl-D-aspartate receptor hypofunction under urethane anesthesia. Neuroscience. vol 237. 2013-09-23. PMID:23396086. in wt mice, mk-801 reduced both spontaneous and elicited hippocampal theta power. 2013-09-23 2023-08-12 mouse
T Kiss, J Feng, W E Hoffmann, C L Shaffer, M Hajó. Rhythmic theta and delta activity of cortical and hippocampal neuronal networks in genetically or pharmacologically induced N-methyl-D-aspartate receptor hypofunction under urethane anesthesia. Neuroscience. vol 237. 2013-09-23. PMID:23396086. age-matched grin1 mice showed abnormal hippocampal field potentials, resembling activity seen after administration of mk-801 in wt mice, but also epileptiform discharges. 2013-09-23 2023-08-12 mouse
P D Lisachev, V O Pustylnyak, M B Shtark, O I Epstei. Induction of S100B gene expression in long-term potentiation in the hippocampal CA1 field depends on activity of NMDA receptors. Bulletin of experimental biology and medicine. vol 154. issue 4. 2013-09-10. PMID:23486587. the effects of nmda receptor blocker mk-801 on the increase in s100b protein mrna content induced by long-term posttetanic potentiation in the hippocampal sections were studied. 2013-09-10 2023-08-12 Not clear
Wendy K Adams, Adam L Halberstadt, Maarten van den Buus. Hippocampal serotonin depletion unmasks differences in the hyperlocomotor effects of phencyclidine and MK-801: quantitative versus qualitative analyses. Frontiers in pharmacology. vol 4. 2013-09-06. PMID:24009584. hippocampal serotonin depletion unmasks differences in the hyperlocomotor effects of phencyclidine and mk-801: quantitative versus qualitative analyses. 2013-09-06 2023-08-12 rat
Wendy K Adams, Adam L Halberstadt, Maarten van den Buus. Hippocampal serotonin depletion unmasks differences in the hyperlocomotor effects of phencyclidine and MK-801: quantitative versus qualitative analyses. Frontiers in pharmacology. vol 4. 2013-09-06. PMID:24009584. here we compared locomotor responses to pcp and mk-801 in rats that were administered 5,7-dihydroxytryptamine (5,7-dht) into either the dorsal or ventral hippocampus, which are preferentially innervated by median and dorsal raphe, respectively. 2013-09-06 2023-08-12 rat