All Relations between Azapirones and serotonin

Publication Sentence Publish Date Extraction Date Species
Yue Du, Qing Li, Yikai Dou, Min Wang, Yu Wang, Yushun Yan, Huanhuan Fan, Xiao Yang, Xiaohong M. Side effects and cognitive benefits of buspirone: A systematic review and meta-analysis. Heliyon. vol 10. issue 7. 2024-04-11. PMID:38601569. buspirone, a 5-hydroxytryptamine 1a (5-ht1a) receptor agonist, has been investigated for its use in various diseases. 2024-04-11 2024-04-13 human
Sheyda Shapouri, Aziz Sharifi, Ole Folkedal, Thomas W K Fraser, Marco A Vinda. Behavioral and neurophysiological effects of buspirone in healthy and depression-like state juvenile salmon. Frontiers in behavioral neuroscience. vol 18. 2024-02-27. PMID:38410095. furthermore, we attempted to reverse this dls-like profile through pharmacological manipulation of the serotonin (5-ht) system with buspirone, an anxiolytic medication that acts as a serotonin receptor agonist (i.e., decreases serotonergic signaling). 2024-02-27 2024-03-02 Not clear
Manas R Biswal, Ryan J Paulson, Riddhi Vichare, Alfred S Lewi. Buspirone Enhances Cell Survival and Preserves Structural Integrity during Oxidative Injury to the Retinal Pigment Epithelium. Antioxidants (Basel, Switzerland). vol 12. issue 12. 2023-12-23. PMID:38136248. the purpose of our study was to determine if buspirone, a partial serotonin 1a (5-ht1a) receptor agonist, protected against oxidative stress-induced changes in the rpe. 2023-12-23 2023-12-25 mouse
Susan J Kea. Gepirone Extended-Release: First Approval. Drugs. 2023-12-11. PMID:38079093. gepirone hcl extended-release (gepirone er; exxua™), an oral, selective serotonin (5ht)1a receptor agonist formulated for once-daily administration, has been developed by fabre-kramer pharmaceuticals, inc. for the treatment of psychiatric disorders, including major depressive disorder (mdd). 2023-12-11 2023-12-17 Not clear
Larissa Sander Magalhães, Dianer Nornberg Strelow, Mariana Parron Paim, Taís da Silva Teixeira Rech, Letícia Devantier Krüger, Antonio Luiz Braga, José Sebastião Santos Neto, César Augusto Brüning, Cristiani Folharini Bortolatt. Anxiolytic-like action of 3-((4-methoxyphenyl)selanyl)-2-phenylbenzofuran (SeBZF3) in mice: A possible contribution of the serotonergic system. Pharmacology, biochemistry, and behavior. 2023-10-04. PMID:37793485. or buspirone (a partial agonist of the 5-ht 2023-10-04 2023-10-07 mouse
Michael Frazure, In Morimoto, Nathan Fielder, Nicholas Mellen, Kimberly Iceman, Teresa Pitt. Serotonin therapies for opioid-induced dysphagia and respiratory depression: sex differences in a rat electromyography model. bioRxiv : the preprint server for biology. 2023-09-04. PMID:37662371. we also evaluated utility of serotonin 5-ht1a agonists (8-oh-dpat and buspirone) to improve swallowing and breathing outcomes following buprenorphine administration. 2023-09-04 2023-09-07 rat
Nicholas G Nasser, Connor Welsh, Avir Mitra, Matthew Swa. Serotonin Syndrome Precipitated by Paxlovid Initiation. Cureus. vol 15. issue 8. 2023-09-04. PMID:37664331. a female in her early 40s taking buspirone, quetiapine, and daily kratom presented to the emergency department two days after starting a course of paxlovid for a mild covid-19 infection with diffuse tremors, ocular clonus, diaphoresis, and confusion consistent with serotonin syndrome (ss). 2023-09-04 2023-09-07 Not clear
Yong-Jik Lee, Hyun-Min Kim, Yoo-Na Jang, Yoon-Mi Han, Hong Seog Seo, Tae Woo Jung, Ji Hoon Jeong, Hyun Jung Lee, Kyung Oh Jun. Buspirone Induces Weight Loss and Normalization of Blood Pressure via the Stimulation of PPAR PPAR research. vol 2023. 2023-05-11. PMID:37168052. buspirone induces weight loss and normalization of blood pressure via the stimulation of ppar buspirone, as a partial agonist for a 5-hydroxytryptamine (serotonin) receptor 1a (5-ht1a), has been prescribed as an anxiolytic drug for patients. 2023-05-11 2023-08-14 Not clear
Sandeep Singh, Alexander Botvinnik, Orr Shahar, Gilly Wolf, Corel Yakobi, Michal Saban, Adham Salama, Amit Lotan, Bernard Lerer, Tzuri Lifschyt. Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder. Translational psychiatry. vol 13. issue 1. 2023-05-10. PMID:37164956. on this background, we set out to explore (1) the role of serotonin 2a (5-ht2a) and serotonin 1a (5-ht1a) receptors in the effect of psilocybin on marble burying; (2) the effect of staggered versus bolus psilocybin administration and persistence of the effect; (3) the effect of the 5-ht1a partial agonist, buspirone, on marble-burying and the head twitch response (htr) induced by psilocybin, a rodent correlate of psychedelic effects. 2023-05-10 2023-08-14 mouse
Henry P Parkman, Katherine P Yates, Irene Sarosiek, Robert S Bulat, Thomas L Abell, Kenneth L Koch, Braden Kuo, Madhusudan Grover, Gianrico Farrugia, Paul Silver, Amirah Abdullah, Alan H Maurer, Zubair Malik, Laura A Miriel, James Tonascia, Frank Hamilton, Pankaj J Pasricha, Richard W McCallu. Buspirone for early satiety and symptoms of gastroparesis: A multi-centre, randomised, placebo-controlled, double-masked trial (BESST). Alimentary pharmacology & therapeutics. 2023-04-13. PMID:37052334. buspirone, a 5-ht 2023-04-13 2023-08-14 Not clear
Yeasong E Ko, Lara S Hw. Serotonin regulation of intermittent and continuous alcohol drinking in male and female C57BL/6J mice with systemic SB242084 and buspirone. Alcohol and alcoholism (Oxford, Oxfordshire). 2023-03-27. PMID:36973222. serotonin regulation of intermittent and continuous alcohol drinking in male and female c57bl/6j mice with systemic sb242084 and buspirone. 2023-03-27 2023-08-14 mouse
Darshak Shah, Mit Joshi, Jigna Shah, Bhoomika M Pate. Beneficial effects of buspirone in endothelin-1 induced stroke cachexia in rats. Molecular and cellular biochemistry. 2023-01-07. PMID:36609633. our study suggests that buspirone produces beneficial role in stroke cachexia by increasing body weight, food intake and adipose tissue depots by activating on 5-ht receptors. 2023-01-07 2023-08-14 rat
Darshak Shah, Mit Joshi, Jigna Shah, Bhoomika M Pate. Beneficial effects of buspirone in endothelin-1 induced stroke cachexia in rats. Molecular and cellular biochemistry. 2023-01-07. PMID:36609633. buspirone decreases circulating blood glucose by stimulating glucose uptake in skeletal muscle via 5-ht receptors and maintained lipid profile. 2023-01-07 2023-08-14 rat
Tarang Taghvaei, Forouzan Elyasi, Zahra Rahbar, Farkhondeh Neyestan. Effectiveness of Buspirone in Patients with Functional Dyspepsia: A Randomized, Double-Blind, Placebo-Controlled Study. Middle East journal of digestive diseases. vol 13. issue 4. 2023-01-06. PMID:36606020. we aimed to assess the effectiveness of buspirone, a 5-hydroxytryptamine (ht) 2023-01-06 2023-08-14 Not clear
S Conti, C Spalletti, M Pasquini, N Giordano, N Barsotti, M Mainardi, S Lai, A Giorgi, M Pasqualetti, S Micera, M Cale. Combining robotics with enhanced serotonin-driven cortical plasticity improves post-stroke motor recovery. Progress in neurobiology. vol 203. 2021-11-11. PMID:33984455. to unveil the translational potentialities of our approach, we specifically targeted the serotonin 1a receptor by delivering buspirone, a clinically approved drug, in stroke mice undergoing robotic rehabilitation. 2021-11-11 2023-08-13 mouse
Benita Jin, Monzurul Alam, Alexa Tierno, Hui Zhong, Roland R Roy, Yury Gerasimenko, Daniel C Lu, V Reggie Edgerto. Serotonergic Facilitation of Forelimb Functional Recovery in Rats with Cervical Spinal Cord Injury. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 18. issue 2. 2021-11-02. PMID:33420588. herein, we compare the effects of buspirone, a 5-ht 2021-11-02 2023-08-13 rat
Jeon-Kyung Kim, Sang-Kap Han, Min-Kyung Joo, Dong-Hyun Ki. Buspirone alleviates anxiety, depression, and colitis; and modulates gut microbiota in mice. Scientific reports. vol 11. issue 1. 2021-10-13. PMID:33731795. buspirone, an agonist for serotonin 5-ht1a receptors, is used for the treatment of anxiety/depression. 2021-10-13 2023-08-13 mouse
Shinichiro Ochi, Takaaki Mori, Jun-Ichi Iga, Shu-Ichi Uen. 5-HT Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology. vol 19. issue 3. 2021-09-01. PMID:34294620. 5-ht to investigate the efficacy of tandospirone, an azapirone anxiolytic similar to buspirone that is used in japan, for behavioral and psychological symptoms of dementia (bpsd), especially in oldest-old patients. 2021-09-01 2023-08-13 Not clear
Long Ma, Jing-Yuan Tang, Jin-Yong Zhou, Chen Zhu, Xin Zhang, Ping Zhou, Qiu Yu, Yan Wang, Xiao-Jian G. Fluoxetine, a selective serotonin reuptake inhibitor used clinically, improves bladder function in a mouse model of moderate spinal cord injury. Neural regeneration research. vol 16. issue 10. 2021-08-21. PMID:33642399. the serotonin agonists quipazine (0.2 mg/kg), 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dapt, 0.1 mg/kg), buspirone (1 mg/kg), sumatriptan (1 mg/kg), and rizatriptan (50 mg/kg), the serotonin reuptake inhibitors fluoxetine (20 mg/kg) and duloxetine (1 mg/kg), and the dopamine receptor agonist skf-82197 (0.1 mg/kg) were intraperitoneally administered to the model mice 35 days post-injury in an acute manner. 2021-08-21 2023-08-13 mouse
Anes Ju, Beatriz Fernandez-Arroyo, Yifan Wu, Débora Jacky, Anna Beyele. Expression of serotonin 1A and 2A receptors in molecular- and projection-defined neurons of the mouse insular cortex. Molecular brain. vol 13. issue 1. 2021-07-08. PMID:32594910. the serotonin (5-ht) system is the target of multiple anxiolytics, including buspirone, which is a partial agonist of the serotonin 1a receptor (5-ht1a). 2021-07-08 2023-08-13 mouse