| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hiroki Sato, Ivan Skelin, Mirko Diksi. Chronic buspirone treatment decreases 5-HT1B receptor densities and the serotonin transporter but increases the density of 5-HT2A receptors in the bulbectomized rat model of depression: an autoradiographic study. Brain research. vol 1345. 2010-10-21. PMID:20501324. |
chronic treatment with buspirone produced the following: 1) a decrease in the 5-ht(1b) densities, which was more pronounced in the sham rats; 2) an increase in the 5-ht(2a) receptor densities, which was more pronounced in the sham rats; and 3) an decrease in 5-htt densities in both groups. |
2010-10-21 |
2023-08-12 |
rat |
| George A Kenn. Medications acting on the serotonergic system for the treatment of alcohol dependent patients. Current pharmaceutical design. vol 16. issue 19. 2010-10-08. PMID:20482508. |
clinical trials have also used the anxiolytic buspirone, a 5-ht(1a) partial agonist, as many alcoholics suffer from anxiety. |
2010-10-08 |
2023-08-12 |
Not clear |
| Alireza M Nayebi, Siyamak R Rad, Mehdi Saberian, Saeid Azimzadeh, Morteza Samin. Buspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-HT(1A) receptors in rats. Pharmacological reports : PR. vol 62. issue 2. 2010-09-27. PMID:20508280. |
buspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-ht(1a) receptors in rats. |
2010-09-27 |
2023-08-12 |
rat |
| Alireza M Nayebi, Siyamak R Rad, Mehdi Saberian, Saeid Azimzadeh, Morteza Samin. Buspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-HT(1A) receptors in rats. Pharmacological reports : PR. vol 62. issue 2. 2010-09-27. PMID:20508280. |
this study aimed to investigate the effect of buspirone, as a partial agonist of 5-ht(1a) receptors, on 6-hydroxydopamine (6-ohda)-induced catalepsy in male wistar rats. |
2010-09-27 |
2023-08-12 |
rat |
| Alireza M Nayebi, Siyamak R Rad, Mehdi Saberian, Saeid Azimzadeh, Morteza Samin. Buspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-HT(1A) receptors in rats. Pharmacological reports : PR. vol 62. issue 2. 2010-09-27. PMID:20508280. |
the effects of buspirone (7.5 mg/kg, ip) and 8-oh-dpat (10 microg/rat, intra-snc) were abolished by 1-(2-methoxyphenyl)-4-[4-(2-phthalimido) butyl]piperazine hydrobromide (nan-190; 10 microg/rat, intra-snc), a 5-ht(1a) receptor antagonist. |
2010-09-27 |
2023-08-12 |
rat |
| Alireza M Nayebi, Siyamak R Rad, Mehdi Saberian, Saeid Azimzadeh, Morteza Samin. Buspirone improves 6-hydroxydopamine-induced catalepsy through stimulation of nigral 5-HT(1A) receptors in rats. Pharmacological reports : PR. vol 62. issue 2. 2010-09-27. PMID:20508280. |
our study indicates that buspirone improves catalepsy in a 6-ohda-induced animal model of parkinson's disease through activation of nigral 5-ht(1a) receptors. |
2010-09-27 |
2023-08-12 |
rat |
| Lin-Lin Wang, An-Kui Yang, Shu-Ming He, Jun Liang, Zhi-Wei Zhou, Yong Li, Shu-Feng Zho. Identification of molecular targets associated with ethanol toxicity and implications in drug development. Current pharmaceutical design. vol 16. issue 11. 2010-08-23. PMID:20184550. |
buspirone), 5-ht(2) receptor antagonists (e.g. |
2010-08-23 |
2023-08-12 |
human |
| P Ken Gillma. Triptans, serotonin agonists, and serotonin syndrome (serotonin toxicity): a review. Headache. vol 50. issue 2. 2010-08-18. PMID:19925619. |
this review considers ss involving serotonin agonists: ergotamine, lysergic acid diethylamide, bromocriptine, and buspirone, as well as triptans, and reviews the experimental foundation underpinning the latest understanding of ss. |
2010-08-18 |
2023-08-12 |
Not clear |
| Neil E Paterson, Michelle Iwunze, Scott F Davis, Sam A Malekiani, Taleen Hanani. Comparison of the predictive validity of the mirror chamber and elevated plus maze tests in mice. Journal of neuroscience methods. vol 188. issue 1. 2010-06-14. PMID:20149823. |
the benzodiazepines chlordiazepoxide and alprazolam and the 5ht(1a) partial agonist buspirone had no effects on anxiety-like behaviors in the mc. |
2010-06-14 |
2023-08-12 |
mouse |
| Rizângela Lyne Mendes de Freitas, Itala Mônica de Sales Santos, Geane Felix de Souza, Adriana da Rocha Tomé, Gláucio Barros Saldanha, Rivelilson Mendes de Freita. Oxidative stress in rat hippocampus caused by pilocarpine-induced seizures is reversed by buspirone. Brain research bulletin. vol 81. issue 4-5. 2010-05-06. PMID:19800952. |
buspirone presents anxyolitic and antidepressant effects due to their ability to stimulate 5-ht(1a) receptor. |
2010-05-06 |
2023-08-12 |
rat |
| Margarita Shumilov, Elka Touito. Buspirone transdermal administration for menopausal syndromes, in vitro and in animal model studies. International journal of pharmaceutics. vol 387. issue 1-2. 2010-05-06. PMID:19961912. |
in this work, we have investigated transdermal administration of buspirone, a 5-ht(1a) receptor agonist, for treatment of the major menopausal syndrome, hot flushes. |
2010-05-06 |
2023-08-12 |
rat |
| Ali Jahanshahi, Lee Wei Lim, Harry W M Steinbusch, Veerle Visser-Vandewalle, Yasin Teme. Buspirone-induced changes in the serotonergic and non-serotonergic cells in the dorsal raphe nucleus of rats. Neuroscience letters. vol 473. issue 2. 2010-04-08. PMID:20178829. |
buspirone, a 5-ht (5-hydroxytryptamine, serotonin)(1a) partial agonist, is being used as an anxiolytic drug. |
2010-04-08 |
2023-08-12 |
rat |
| Ali Jahanshahi, Lee Wei Lim, Harry W M Steinbusch, Veerle Visser-Vandewalle, Yasin Teme. Buspirone-induced changes in the serotonergic and non-serotonergic cells in the dorsal raphe nucleus of rats. Neuroscience letters. vol 473. issue 2. 2010-04-08. PMID:20178829. |
here, we investigated the effect of acute and chronic buspirone treatments on the 5-ht and non-5-ht cells, the neuronal nitric oxide synthase (nnos) and tyrosine hydroxylase (th) cells, in the drn. |
2010-04-08 |
2023-08-12 |
rat |
| Ali Jahanshahi, Lee Wei Lim, Harry W M Steinbusch, Veerle Visser-Vandewalle, Yasin Teme. Buspirone-induced changes in the serotonergic and non-serotonergic cells in the dorsal raphe nucleus of rats. Neuroscience letters. vol 473. issue 2. 2010-04-08. PMID:20178829. |
meanwhile only the chronic buspirone treatment reduced the mean density of 5-ht and th immunoreactivity but not the acute buspirone as compared to saline treated animals. |
2010-04-08 |
2023-08-12 |
rat |
| Ali Jahanshahi, Lee Wei Lim, Harry W M Steinbusch, Veerle Visser-Vandewalle, Yasin Teme. Buspirone-induced changes in the serotonergic and non-serotonergic cells in the dorsal raphe nucleus of rats. Neuroscience letters. vol 473. issue 2. 2010-04-08. PMID:20178829. |
our findings suggest that buspirone treatment affects not only the intracellular content of 5-ht but also nnos and th. |
2010-04-08 |
2023-08-12 |
rat |
| Susan A Brunelli, Jessica A Aviles, Kimberly S Gannon, Aron Branscomb, Sharon Shacha. PRX-00023, a selective serotonin 1A receptor agonist, reduces ultrasonic vocalizations in infant rats bred for high infantile anxiety. Pharmacology, biochemistry, and behavior. vol 94. issue 1. 2009-12-17. PMID:19576924. |
in this study, rates of usv in high line infants (pups: postnatal day 11+/-1) were compared to those of randomly-bred controls in response to epix compound prx-00023, a unique serotonin (5-ht) agonist, acting exclusively at the 5-ht1a receptor, or buspirone, a nonspecific 5ht1a agonist. |
2009-12-17 |
2023-08-12 |
rat |
| Zachary Bencan, Damiyon Sledge, Edward D Levi. Buspirone, chlordiazepoxide and diazepam effects in a zebrafish model of anxiety. Pharmacology, biochemistry, and behavior. vol 94. issue 1. 2009-12-17. PMID:19643124. |
buspirone, a serotonergic (5ht(1a) receptor agonist) anxiolytic drug with some d(2) dopaminergic effect, had a pronounced anxiolytic-like effect in the zebrafish diving model at doses that did not have sedative effects. |
2009-12-17 |
2023-08-12 |
zebrafish |
| Hiroto Miwa, A Nagahara, K Tominaga, T Yokoyama, Y Sawada, K Inoue, Kiyoshi Ashida, T Fukuchi, M Hojo, H Yamashita, T Tomita, K Hori, T Oshim. Efficacy of the 5-HT1A agonist tandospirone citrate in improving symptoms of patients with functional dyspepsia: a randomized controlled trial. The American journal of gastroenterology. vol 104. issue 11. 2009-12-01. PMID:19638966. |
the aim of this study was to examine the efficacy of tandospirone citrate, a new partial agonist of the 5-hydroxytryptamine 1a (5-ht1a) receptor, in improving the symptoms of patients with fd. |
2009-12-01 |
2023-08-12 |
Not clear |
| Danijela Piskulić, James S Olver, Paul Maruff, Trevor R Norma. Treatment of cognitive dysfunction in chronic schizophrenia by augmentation of atypical antipsychotics with buspirone, a partial 5-HT(1A) receptor agonist. Human psychopharmacology. vol 24. issue 6. 2009-10-20. PMID:19637398. |
treatment of cognitive dysfunction in chronic schizophrenia by augmentation of atypical antipsychotics with buspirone, a partial 5-ht(1a) receptor agonist. |
2009-10-20 |
2023-08-12 |
Not clear |
| Hiroyo Koseki, Machiko Matsumoto, Hiroko Togashi, Yoshihide Miura, Kazuaki Fukushima, Mitsuhiro Yoshiok. Alteration of synaptic transmission in the hippocampal-mPFC pathway during extinction trials of context-dependent fear memory in juvenile rat stress models. Synapse (New York, N.Y.). vol 63. issue 9. 2009-10-09. PMID:19504621. |
the neuronal and behavioral deficits observed in the 3w-fs group were prevented by pretreatment with the serotonin(1a) receptor agonist tandospirone (1 mg/kg, i.p.). |
2009-10-09 |
2023-08-12 |
rat |