| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Eriksen, M J Drus. Astrocyte-mediated trophic support of developing serotonin neurons: effects of ethanol, buspirone, and S100B. Brain research. Developmental brain research. vol 131. issue 1-2. 2002-02-04. PMID:11718831. |
our observations suggest that the protective effects of buspirone on ethanol-exposed, developing 5-ht neurons are mediated in part by the astrocyte-produced factor s100b. |
2002-02-04 |
2023-08-12 |
mouse |
| A Boido, C C Boido, F Sparator. Synthesis and pharmacological evaluation of aryl/heteroaryl piperazinyl alkyl benzotriazoles as ligands for some serotonin and dopamine receptor subtypes. Farmaco (Societa chimica italiana : 1989). vol 56. issue 4. 2001-12-04. PMID:11421254. |
the synthesized compounds displayed from moderate to good affinity to the serotonin 5-ht1a receptor and only modest or poor affinity to the dopamine d2 receptor, similar to buspirone. |
2001-12-04 |
2023-08-12 |
mouse |
| S Miyata, T Hamamura, J Yoshinaga, Y Nakamura, T Imamura, A Hikiji, S Kurod. Amelioration of frozen gait by tandospirone, a serotonin 1A agonist, in a patient with pure akinesia developing resistance to L-threo-3,4-dihydroxyphenylserine. Clinical neuropharmacology. vol 24. issue 4. 2001-12-04. PMID:11479395. |
amelioration of frozen gait by tandospirone, a serotonin 1a agonist, in a patient with pure akinesia developing resistance to l-threo-3,4-dihydroxyphenylserine. |
2001-12-04 |
2023-08-12 |
Not clear |
| S Miyata, T Hamamura, J Yoshinaga, Y Nakamura, T Imamura, A Hikiji, S Kurod. Amelioration of frozen gait by tandospirone, a serotonin 1A agonist, in a patient with pure akinesia developing resistance to L-threo-3,4-dihydroxyphenylserine. Clinical neuropharmacology. vol 24. issue 4. 2001-12-04. PMID:11479395. |
we then combined administration of tandospirone, a serotonin (5-ht) 1a agonist with l-threo-dops (600 mg/d), resulting in marked clinical improvement. |
2001-12-04 |
2023-08-12 |
Not clear |
| S Miyata, T Hamamura, J Yoshinaga, Y Nakamura, T Imamura, A Hikiji, S Kurod. Amelioration of frozen gait by tandospirone, a serotonin 1A agonist, in a patient with pure akinesia developing resistance to L-threo-3,4-dihydroxyphenylserine. Clinical neuropharmacology. vol 24. issue 4. 2001-12-04. PMID:11479395. |
tandospirone is reported to activate noradrenergic neurons via the 5-ht 1a receptor, which could account for such striking improvement in a patient previously responsive to the noradrenergic precursor l-threo-dops given alone. |
2001-12-04 |
2023-08-12 |
Not clear |
| N Le Marec, A R Ase, T Botez-Marquard, L Marchand, T A Reader, R Lalond. Behavioral and biochemical effects of L-tryptophan and buspirone in a model of cerebellar atrophy. Pharmacology, biochemistry, and behavior. vol 69. issue 3-4. 2001-12-04. PMID:11509189. |
the purpose of this study was to determine whether the motor coordination deficits of lurcher mutants could be improved after chronic administration of the serotonin (5-hydroxytryptamine; 5-ht) precursor, l-tryptophan, or of the 5-ht(1a) agonist, buspirone. |
2001-12-04 |
2023-08-12 |
mouse |
| N Le Marec, A R Ase, T Botez-Marquard, L Marchand, T A Reader, R Lalond. Behavioral and biochemical effects of L-tryptophan and buspirone in a model of cerebellar atrophy. Pharmacology, biochemistry, and behavior. vol 69. issue 3-4. 2001-12-04. PMID:11509189. |
in contrast, buspirone led to 5-ht increases in cerebellum and augmented 5-hiaa in the spinal cord. |
2001-12-04 |
2023-08-12 |
mouse |
| K Mori, H Togashi, T Kojima, M Matsumoto, S Ohashi, K Ueno, M Yoshiok. Different effects of anxiolytic agents, diazepam and 5-HT(1A) agonist tandospirone, on hippocampal long-term potentiation in vivo. Pharmacology, biochemistry, and behavior. vol 69. issue 3-4. 2001-12-04. PMID:11509193. |
different effects of anxiolytic agents, diazepam and 5-ht(1a) agonist tandospirone, on hippocampal long-term potentiation in vivo. |
2001-12-04 |
2023-08-12 |
Not clear |
| K Mori, H Togashi, T Kojima, M Matsumoto, S Ohashi, K Ueno, M Yoshiok. Different effects of anxiolytic agents, diazepam and 5-HT(1A) agonist tandospirone, on hippocampal long-term potentiation in vivo. Pharmacology, biochemistry, and behavior. vol 69. issue 3-4. 2001-12-04. PMID:11509193. |
in the present study, we compared the effects of diazepam and 5-ht(1a) agonist, tandospirone, on hippocampal long-term potentiation (ltp) in schaffer collateral-ca1, mossy fiber-ca3 and perforant path-dentate gyrus synapses. |
2001-12-04 |
2023-08-12 |
Not clear |
| K Mori, H Togashi, T Kojima, M Matsumoto, S Ohashi, K Ueno, M Yoshiok. Different effects of anxiolytic agents, diazepam and 5-HT(1A) agonist tandospirone, on hippocampal long-term potentiation in vivo. Pharmacology, biochemistry, and behavior. vol 69. issue 3-4. 2001-12-04. PMID:11509193. |
thus, there was a discrepancy in the effects on hippocampal ltp between diazepam and tandospirone, possibly reflecting the reported clinical properties of these drugs, in that 5-ht(1a) partial agonists do not affect learning and memory, whereas diazepam impairs memory function. |
2001-12-04 |
2023-08-12 |
Not clear |
| K Brøsen, C A Naranj. Review of pharmacokinetic and pharmacodynamic interaction studies with citalopram. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 11. issue 4. 2001-12-04. PMID:11532381. |
at the pharmacodynamic level there have been a few documented cases of serotonin syndrome with citalopram and moclobemide and buspirone. |
2001-12-04 |
2023-08-12 |
human |
| M Mokhtarani, A N Mahgoub, N Morioka, A G Doufas, M Dae, T E Shaughnessy, A R Bjorksten, D I Sessle. Buspirone and meperidine synergistically reduce the shivering threshold. Anesthesia and analgesia. vol 93. issue 5. 2001-12-04. PMID:11682404. |
we tested the hypothesis that the combination of buspirone (a serotonin 1a partial agonist) and meperidine synergistically reduces the shivering threshold (triggering tympanic membrane temperature) to at least 34 degrees c while producing little sedation or respiratory depression. |
2001-12-04 |
2023-08-12 |
human |
| T Sumiyoshi, M Matsui, S Nohara, I Yamashita, M Kurachi, C Sumiyoshi, K Jayathilake, H Y Meltze. Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment. The American journal of psychiatry. vol 158. issue 10. 2001-11-01. PMID:11579010. |
the goal of this study was to evaluate the effects of the addition of tandospirone, a serotonin-1a (5-ht(1a)) agonist, to ongoing treatment with typical antipsychotic drugs, on two cognitive domains that are relevant to functional outcome in patients with schizophrenia. |
2001-11-01 |
2023-08-12 |
Not clear |
| Y Kaneda, A Fuji. Effects of tandospirone, a serotonin-1A agonist, on the hypothalamo-pituitary-gonadal axis of male patients. Neuro endocrinology letters. vol 22. issue 4. 2001-10-25. PMID:11524630. |
a small study was conducted on male patients with generalized anxiety disorders to investigate the clinical and neuroendocrinological effects of the 5-ht(1a) receptor agonist tandospirone (tds) on the hypothalamo-pituitary-gonadal (hpg) axis. |
2001-10-25 |
2023-08-12 |
Not clear |
| A Bronowska, A Leś, Z Chilmonczyk, S Filipek, O Edvardsen, R Ostensen, I Sylt. Molecular dynamics of buspirone analogues interacting with the 5-HT1A and 5-HT2A serotonin receptors. Bioorganic & medicinal chemistry. vol 9. issue 4. 2001-10-11. PMID:11354671. |
molecular dynamics of buspirone analogues interacting with the 5-ht1a and 5-ht2a serotonin receptors. |
2001-10-11 |
2023-08-12 |
human |
| A Bronowska, A Leś, Z Chilmonczyk, S Filipek, O Edvardsen, R Ostensen, I Sylt. Molecular dynamics of buspirone analogues interacting with the 5-HT1A and 5-HT2A serotonin receptors. Bioorganic & medicinal chemistry. vol 9. issue 4. 2001-10-11. PMID:11354671. |
three-dimensional (3-d) models of the human serotonin 5-ht1a and 5-ht2a receptors were constructed, energy refined, and used to study the interactions with a series of buspirone analogues. |
2001-10-11 |
2023-08-12 |
human |
| J L Eriksen, M J Drus. Potential involvement of S100B in the protective effects of a serotonin-1a agonist on ethanol-treated astrocytes. Brain research. Developmental brain research. vol 128. issue 2. 2001-09-06. PMID:11412901. |
the present in vitro studies extended our prior in vivo work by examining the potential involvement of s100b with the protective effects of a 5-ht(1a) agonist, i.e., buspirone, on astrocytes. |
2001-09-06 |
2023-08-12 |
mouse |
| J L Eriksen, M J Drus. Potential involvement of S100B in the protective effects of a serotonin-1a agonist on ethanol-treated astrocytes. Brain research. Developmental brain research. vol 128. issue 2. 2001-09-06. PMID:11412901. |
these investigations demonstrate that in vitro ethanol exposure reduces the number of astrocytes, and that treatment with the 5-ht(1a) agonist buspirone prevents the ethanol-associated reduction in astrocyte number. |
2001-09-06 |
2023-08-12 |
mouse |
| T Sumiyoshi, M Matsui, I Yamashita, S Nohara, M Kurachi, T Uehara, S Sumiyoshi, C Sumiyoshi, H Y Meltze. The effect of tandospirone, a serotonin(1A) agonist, on memory function in schizophrenia. Biological psychiatry. vol 49. issue 10. 2001-08-23. PMID:11343682. |
the effect of tandospirone, a serotonin(1a) agonist, on memory function in schizophrenia. |
2001-08-23 |
2023-08-12 |
Not clear |
| T Sumiyoshi, M Matsui, I Yamashita, S Nohara, M Kurachi, T Uehara, S Sumiyoshi, C Sumiyoshi, H Y Meltze. The effect of tandospirone, a serotonin(1A) agonist, on memory function in schizophrenia. Biological psychiatry. vol 49. issue 10. 2001-08-23. PMID:11343682. |
the purpose of this study was to test the hypothesis that the addition of tandospirone, a 5-ht(1a) partial agonist, to ongoing treatment with typical antipsychotic drugs, would improve memory function in patients with schizophrenia. |
2001-08-23 |
2023-08-12 |
Not clear |