| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Megna, M O'del. Ataxia from lithium toxicity successfully treated with high-dose buspirone: a single-case experimental design. Archives of physical medicine and rehabilitation. vol 82. issue 8. 2001-08-23. PMID:11494197. |
recent studies investigating use of serotonin agonists in the treatment of ataxia have produced mixed results; however, buspirone with an affinity specific to the 5-hydroxytryptamine(1a) subreceptors has shown promise. |
2001-08-23 |
2023-08-12 |
Not clear |
| A S Adeagbo, E A Kadavil, M Yousif, M A Oriow. Buspirone, a 5-HT(1A) receptor agonist, dilates the perfused rat uterine vascular bed through alpha(1)-adrenoceptor blockade. General pharmacology. vol 34. issue 5. 2001-08-09. PMID:11368892. |
buspirone, a 5-ht(1a) receptor agonist, dilates the perfused rat uterine vascular bed through alpha(1)-adrenoceptor blockade. |
2001-08-09 |
2023-08-12 |
rat |
| A S Adeagbo, E A Kadavil, M Yousif, M A Oriow. Buspirone, a 5-HT(1A) receptor agonist, dilates the perfused rat uterine vascular bed through alpha(1)-adrenoceptor blockade. General pharmacology. vol 34. issue 5. 2001-08-09. PMID:11368892. |
buspirone, a selective 5-ht(1a) receptor agonist, was not effective at low doses but produced a response at high doses. |
2001-08-09 |
2023-08-12 |
rat |
| A S Adeagbo, E A Kadavil, M Yousif, M A Oriow. Buspirone, a 5-HT(1A) receptor agonist, dilates the perfused rat uterine vascular bed through alpha(1)-adrenoceptor blockade. General pharmacology. vol 34. issue 5. 2001-08-09. PMID:11368892. |
when perfusion pressure was raised with phenylephrine, responses to 5-ht were enhanced while buspirone produced dose-dependent vasodilator responses. |
2001-08-09 |
2023-08-12 |
rat |
| B G Appelberg, E K Syvälahti, T E Koskinen, O P Mehtonen, T T Muhonen, H H Naukkarine. Patients with severe depression may benefit from buspirone augmentation of selective serotonin reuptake inhibitors: results from a placebo-controlled, randomized, double-blind, placebo wash-in study. The Journal of clinical psychiatry. vol 62. issue 6. 2001-08-02. PMID:11465522. |
patients with severe depression may benefit from buspirone augmentation of selective serotonin reuptake inhibitors: results from a placebo-controlled, randomized, double-blind, placebo wash-in study. |
2001-08-02 |
2023-08-12 |
Not clear |
| B G Appelberg, E K Syvälahti, T E Koskinen, O P Mehtonen, T T Muhonen, H H Naukkarine. Patients with severe depression may benefit from buspirone augmentation of selective serotonin reuptake inhibitors: results from a placebo-controlled, randomized, double-blind, placebo wash-in study. The Journal of clinical psychiatry. vol 62. issue 6. 2001-08-02. PMID:11465522. |
although case reports and open studies have reported augmentation with buspirone to be beneficial in the treatment of depression refractory to treatment with a selective serotonin reuptake inhibitor (ssri), a recently published randomized, placebo-controlled, double-blind study failed to show superiority of buspirone over placebo in this respect. |
2001-08-02 |
2023-08-12 |
Not clear |
| I Sylte, A Bronowska, S G Dah. Ligand induced conformational states of the 5-HT(1A) receptor. European journal of pharmacology. vol 416. issue 1-2. 2001-07-26. PMID:11282110. |
in the present study, the amber 5.0 force field was used for comparative molecular dynamics simulations of a 5-ht(1a) receptor model in the absence of ligand, in complex with a 5-ht(1a) receptor agonist (r)-8-hydroxy-2-(di-n-propylamino)tetralin [(r)-8-oh-dpat], in complex with a selective 5-ht(1a) receptor antagonist (s)-n-tert-butyl-3-[4-(2-methoxyphenyl)piperazin-1-yl ]-2-phenylpropanamide [(s)-way100135], and in complex with the partial agonist, buspirone. |
2001-07-26 |
2023-08-12 |
Not clear |
| G Milligan, E Kellett, C Dacquet, V Dubreuil, E Jacoby, M J Millan, G Lavielle, M Speddin. S 14506: novel receptor coupling at 5-HT(1A) receptors. Neuropharmacology. vol 40. issue 3. 2001-07-19. PMID:11166326. |
antagonists (way 100635, way 100135) and inverse agonists (spiperone and metitepine) displaced [(3)h]-s 14506 binding with high affinity and hill slopes close to unity, whereas agonists (5-ht and 5-ct) displayed low affinity with low hill slopes: partial agonists (buspirone, ipsapirone) showed intermediate properties. |
2001-07-19 |
2023-08-12 |
Not clear |
| F Miranda, E Hong, D N Velázquez-Martíne. Discriminative stimulus properties of indorenate in a conditioned taste aversion paradigm. Pharmacology, biochemistry, and behavior. vol 68. issue 3. 2001-07-19. PMID:11325395. |
in two-bottle generalization tests (one bottle containing saccharin, the other plain water), the preference for saccharin was evaluated after different doses of indo, [3h]-8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) (5-ht(1a)), buspirone (5-ht(1a)), ru24969 (5-ht(1a/1b)), tfmpp (5-ht(1b/2c)), mk212 (5-ht(2c)), alpha-me-5-ht (5-ht(2c/2a)), 2-me-5-ht (5-ht(3)) and cisapride (5-ht(4)). |
2001-07-19 |
2023-08-12 |
rat |
| Y Kaneda, T Ohmori, H Okab. Possible mild serotonin syndrome related to co-prescription of tandospirone and trazodone. General hospital psychiatry. vol 23. issue 2. 2001-07-05. PMID:11354048. |
possible mild serotonin syndrome related to co-prescription of tandospirone and trazodone. |
2001-07-05 |
2023-08-12 |
Not clear |
| K D Wagne. Generalized anxiety disorder in children and adolescents. The Psychiatric clinics of North America. vol 24. issue 1. 2001-06-21. PMID:11225504. |
preliminary data support the potential efficacy of selective serotonin reuptake inhibitors, buspirone, and high-potency benzodiazepines. |
2001-06-21 |
2023-08-12 |
Not clear |
| P Anderer, B Saletu, R D Pascual-Marqu. Effect of the 5-HT(1A) partial agonist buspirone on regional brain electrical activity in man: a functional neuroimaging study using low-resolution electromagnetic tomography (LORETA). Psychiatry research. vol 100. issue 2. 2001-05-31. PMID:11114494. |
effect of the 5-ht(1a) partial agonist buspirone on regional brain electrical activity in man: a functional neuroimaging study using low-resolution electromagnetic tomography (loreta). |
2001-05-31 |
2023-08-12 |
human |
| P Anderer, B Saletu, R D Pascual-Marqu. Effect of the 5-HT(1A) partial agonist buspirone on regional brain electrical activity in man: a functional neuroimaging study using low-resolution electromagnetic tomography (LORETA). Psychiatry research. vol 100. issue 2. 2001-05-31. PMID:11114494. |
in a double-blind, placebo-controlled study, the effects of 20 mg buspirone - a 5-ht(1a) partial agonist - on regional electrical generators within the human brain were investigated utilizing three-dimensional eeg tomography. |
2001-05-31 |
2023-08-12 |
human |
| A W Wilson, B Costall, J C Neil. Manipulation of operant responding for an ethanol-paired conditioned stimulus in the rat by pharmacological alteration of the serotonergic system. Journal of psychopharmacology (Oxford, England). vol 14. issue 4. 2001-05-31. PMID:11198050. |
results showed that the 5-ht releaser d-fenfluramine, the selective serotonin reuptake inhibitor fluoxetine, the 5-ht1a receptor agonist 8-hydroxy-2[di-n-propylamino]tetralin, the partial 5-ht1a receptor agonist buspirone, and the 5-ht1b/5-ht2c receptor agonist 1-(3-trifluoromethylphenyl)piperazine, but not the 5-ht2a/5-ht2c receptor agonist 1-(2,5-dimethoxy-4-iodophenylaminopropane)-2, selectively reduced responding on a lever leading to presentation of an ethanol paired conditioned stimulus. |
2001-05-31 |
2023-08-12 |
rat |
| A Newman-Tancredi, L Verrièle, M J Milla. Differential modulation by GTPgammaS of agonist and inverse agonist binding to h5-HT(1A) receptors revealed by [3H]-WAY100,635. British journal of pharmacology. vol 132. issue 2. 2001-05-03. PMID:11159702. |
agonists, including 5-ht, 8-oh-dpat and buspirone, displayed biphasic isotherms which shifted to the right in the presence of gtpgammas. |
2001-05-03 |
2023-08-12 |
human |
| A Bronowska, I Sylte, Ø Edvardsen, R Østensen, A Leś, Z Chilmonczy. Theoretical models of interactions between buspirone analogues and 5-HT1A and 5-HT2A serotonin receptor subtypes. Acta poloniae pharmaceutica. vol 57 Suppl. 2001-05-03. PMID:11293260. |
in present study the structure-selectivity relationship of buspirone and six of its analogues towards 5-ht1a and 5-ht2a serotonin receptors was investigated on molecular level. |
2001-05-03 |
2023-08-12 |
human |
| K Pruus, T Skrebuhhova-Malmros, R Rudissaar, V Matto, L Allikmet. 5-HT1A receptor agonists buspirone and gepirone attenuate apomorphine-induced aggressive behaviour in adult male Wistar rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 51. issue 4 Pt 2. 2001-03-22. PMID:11220492. |
we have studied the effects of acute serotonin (5-ht) 5-ht1a receptor agonist buspirone (0.5, 1.0, 2.5 and 5.0 mg/kg, s.c.), gepirone (5.0 and 10 mg/kg, s.c.), and 8-oh-dpat (0.1, 0.25, and 0.5 mg/kg, i.p.) |
2001-03-22 |
2023-08-12 |
rat |
| M B Assié, W Koe. Estimation of apparent pA2 values for WAY 100635 at 5-HT1A receptors regulating 5-hydroxytryptamine release in anaesthetised rats. European journal of pharmacology. vol 409. issue 2. 2001-02-15. PMID:11104831. |
administration of cumulative doses of (+/-)-8-hydroxy-2-(di-n-propylamino)tetralin (8-oh-dpat) (0.01-40 mg/kg), 1[2-(4-fluorobenzoylamino)ethyl]-4-(7-methoxynaphtyl)pipe razine (s 14506) (0.00063-2.5 mg/kg), or buspirone (0.16-40 mg/kg), dose-dependently decreased the extracellular concentrations of 5-ht in the ventral hippocampus. |
2001-02-15 |
2023-08-12 |
rat |
| M B Assié, W Koe. Estimation of apparent pA2 values for WAY 100635 at 5-HT1A receptors regulating 5-hydroxytryptamine release in anaesthetised rats. European journal of pharmacology. vol 409. issue 2. 2001-02-15. PMID:11104831. |
taken together, the results are evidence that buspirone, s 14506 and 8-oh-dpat, administered in cumulative doses, decreased 5-ht release by activating similar 5-ht1a receptors, because a common apparent pa2 value was obtained for way 100635. |
2001-02-15 |
2023-08-12 |
rat |
| K Suemaru, H Araki, Y Gomit. Involvement of 5-hydroxytryptamine(1A) receptors in nicotine-induced tail tremor in rats. European journal of pharmacology. vol 408. issue 1. 2001-01-26. PMID:11070179. |
the 5-ht(1a) receptor agonists, buspirone (1-20 mg/kg, i.p. |
2001-01-26 |
2023-08-12 |
rat |