| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G H Mano. Possible serotonin syndrome associated with buspirone added to fluoxetine. The Annals of pharmacotherapy. vol 34. issue 7-8. 2001-01-12. PMID:10928399. |
possible serotonin syndrome associated with buspirone added to fluoxetine. |
2001-01-12 |
2023-08-12 |
Not clear |
| G H Mano. Possible serotonin syndrome associated with buspirone added to fluoxetine. The Annals of pharmacotherapy. vol 34. issue 7-8. 2001-01-12. PMID:10928399. |
to report the development of a possible serotonin syndrome in a patient taking buspirone and fluoxetine. |
2001-01-12 |
2023-08-12 |
Not clear |
| M Hascoët, M Bourin, B A Nic Dhonnchadh. The influence of buspirone, and its metabolite 1-PP, on the activity of paroxetine in the mouse light/dark paradigm and four plates test. Pharmacology, biochemistry, and behavior. vol 67. issue 1. 2001-01-04. PMID:11113483. |
in the light/dark paradigm, both doses of buspirone significantly potentiated paroxetine, while in the four plates only one dose of buspirone (a 5ht(1a) partial agonist) (0.06 mg/kg) increased the anxiolytic-like effect of paroxetine. |
2001-01-04 |
2023-08-12 |
mouse |
| M Hascoët, M Bourin, B A Nic Dhonnchadh. The influence of buspirone, and its metabolite 1-PP, on the activity of paroxetine in the mouse light/dark paradigm and four plates test. Pharmacology, biochemistry, and behavior. vol 67. issue 1. 2001-01-04. PMID:11113483. |
buspirone seemed to emphasize the role of paroxetine in 5-ht(1a) receptor modulation and exerted a biphasic influence in the two tests. |
2001-01-04 |
2023-08-12 |
mouse |
| Y Maki, T Inoue, T Izumi, I Muraki, K Ito, Y Kitaichi, X Li, T Koyam. Monoamine oxidase inhibitors reduce conditioned fear stress-induced freezing behavior in rats. European journal of pharmacology. vol 406. issue 3. 2000-12-11. PMID:11040348. |
the selective serotonin 1a receptor agonist tandospirone (0.1-10 mg/kg) inhibited freezing dose dependently. |
2000-12-11 |
2023-08-12 |
rat |
| L Cervo, C Munoz, A Bertaglia, R Samani. Alnespirone and buspirone have anxiolytic-like effects in a conflict procedure in rats by stimulating 5-HT(1A) receptors. Behavioural pharmacology. vol 11. issue 2. 2000-11-13. PMID:10877120. |
alnespirone and buspirone have anxiolytic-like effects in a conflict procedure in rats by stimulating 5-ht(1a) receptors. |
2000-11-13 |
2023-08-12 |
rat |
| L Cervo, C Munoz, A Bertaglia, R Samani. Alnespirone and buspirone have anxiolytic-like effects in a conflict procedure in rats by stimulating 5-HT(1A) receptors. Behavioural pharmacology. vol 11. issue 2. 2000-11-13. PMID:10877120. |
we studied the anxiolytic-like activity of alnespirone and buspirone, two 5-ht(1a) receptor agonists, in a modified geller-seifter conflict model, and examined the role of 5-ht(1a) receptors by studying whether way-100635, a selective antagonist at these receptors, blocked their effects. |
2000-11-13 |
2023-08-12 |
rat |
| L Cervo, C Munoz, A Bertaglia, R Samani. Alnespirone and buspirone have anxiolytic-like effects in a conflict procedure in rats by stimulating 5-HT(1A) receptors. Behavioural pharmacology. vol 11. issue 2. 2000-11-13. PMID:10877120. |
the results suggest that alnespirone and buspirone have anxiolytic-like activity in a conflict procedure by stimulating 5-ht(1a) receptors, presumably at a presynaptic level. |
2000-11-13 |
2023-08-12 |
rat |
| E A Rabiner, R N Gunn, M R Wilkins, P A Sargent, E Mocaer, E Sedman, P J Cowen, P M Grasb. Drug action at the 5-HT(1A) receptor in vivo: autoreceptor and postsynaptic receptor occupancy examined with PET and [carbonyl-(11)C]WAY-100635. Nuclear medicine and biology. vol 27. issue 5. 2000-11-03. PMID:10962259. |
all drugs, apart from buspirone, displayed occupancy at the 5-ht(1a) receptor site. |
2000-11-03 |
2023-08-12 |
human |
| B Andrée, C Halldin, S O Thorberg, J Sandell, L Fard. Use of PET and the radioligand [carbonyl-(11)C]WAY-100635 in psychotropic drug development. Nuclear medicine and biology. vol 27. issue 5. 2000-11-03. PMID:10962260. |
it was confirmed that the reference ligand 8-oh-dpat and psychoactive drugs such as buspirone and pindolol occupies 5-ht(1a) receptors in the primate brain. |
2000-11-03 |
2023-08-12 |
human |
| M Siemiatkowski, H Sienkiewicz-Jarosz, A I Członkowska, A Bidziński, A Płaźni. Effects of buspirone, diazepam, and zolpidem on open field behavior, and brain [3H]muscimol binding after buspirone pretreatment. Pharmacology, biochemistry, and behavior. vol 66. issue 3. 2000-10-05. PMID:10899383. |
the effects of 5-ht(1a) receptor agonist buspirone, a nonselective (diazepam), and a selective (zolpidem) gaba(a) receptor agonist were compared in the open field test of neophobia. |
2000-10-05 |
2023-08-12 |
rat |
| T Hata, E Itoh, H Nishikaw. [Stress-induced anxiety and endogenous anxiogenic substances]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 115. issue 1. 2000-09-28. PMID:10876811. |
emotional behavior in those stressed animals were attenuated by anxiolytics like diazepam, a benzodiazepine receptor agonist and buspirone, a serotonin (5-ht) 1a agonist. |
2000-09-28 |
2023-08-12 |
rat |
| J L Eriksen, R A Gillespie, M J Drus. Effects of in utero ethanol exposure and maternal treatment with a 5-HT(1A) agonist on S100B-containing glial cells. Brain research. Developmental brain research. vol 121. issue 2. 2000-09-14. PMID:10876026. |
to test our hypothesis, we determined the effects of in utero ethanol exposure and maternal treatments with the 5-ht(1a) agonists ipsapirone and buspirone on s100b immunopositive glial cells. |
2000-09-14 |
2023-08-12 |
rat |
| A Malmberg, P G Strang. Site-directed mutations in the third intracellular loop of the serotonin 5-HT(1A) receptor alter G protein coupling from G(i) to G(s) in a ligand-dependent manner. Journal of neurochemistry. vol 75. issue 3. 2000-09-12. PMID:10936212. |
serotonin, (r)-8-hydroxy-2-dipropylaminotetralin [(r)-8-oh-dpat], and buspirone inhibited cyclic amp production in cells expressing native and mutant 5-ht(1a) receptors. |
2000-09-12 |
2023-08-12 |
human |
| M F O'Neill, D R Dobson, G J Sange. 5-HT(1B/D) receptor agonist, SKF99101H, induces locomotor hyperactivity in the guinea pig. European journal of pharmacology. vol 399. issue 1. 2000-08-24. PMID:10876022. |
previous studies in guinea pigs have shown that while a serotonin 5-ht(1b/d) receptor agonist, gr46611, does not induce locomotor activation when given alone, it markedly enhances the locomotor response to selective 5-ht(1a) receptor agonists, 8-oh-dpat and buspirone. |
2000-08-24 |
2023-08-12 |
Not clear |
| T A Reader, A R Ase, N Le Marec, R Lalond. Effects of buspirone on brain indoleamines and catecholamines in wild-type mice and Lurcher mutants. European journal of pharmacology. vol 398. issue 1. 2000-08-10. PMID:10856446. |
in lc/+ mutants, the effects of buspirone were attenuated, but higher l-tryptophan and indoleamine levels, suggest a storage of serotonin in a non-releasable compartment. |
2000-08-10 |
2023-08-12 |
mouse |
| S F de Boer, M Lesourd, E Mocaër, J M Koolhaa. Somatodendritic 5-HT(1A) autoreceptors mediate the anti-aggressive actions of 5-HT(1A) receptor agonists in rats: an ethopharmacological study with S-15535, alnespirone, and WAY-100635. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 1. 2000-07-17. PMID:10869883. |
the drug's profound anti-aggressive actions were not accompanied by sedative side effects or signs of the "5-ht(1a) receptor-mediated behavioral syndrome," which are characteristically induced by prototypical 5-ht(1a) receptor agonists like 8-oh-dpat and buspirone. |
2000-07-17 |
2023-08-12 |
rat |
| J H Kehne, S Coverdale, T C McCloskey, D C Hoffman, J V Cassell. Effects of the CRF(1) receptor antagonist, CP 154,526, in the separation-induced vocalization anxiolytic test in rat pups. Neuropharmacology. vol 39. issue 8. 2000-07-12. PMID:10818252. |
siv was reduced by cp 154,526 at doses that did not affect tip or negative geotaxis, a profile like that of the 5-ht(1a) partial agonist buspirone. |
2000-07-12 |
2023-08-12 |
rat |
| N M Rupniak, E C Carlson, T Harrison, B Oates, E Seward, S Owen, C de Felipe, S Hunt, A Wheeldo. Pharmacological blockade or genetic deletion of substance P (NK(1)) receptors attenuates neonatal vocalisation in guinea-pigs and mice. Neuropharmacology. vol 39. issue 8. 2000-07-12. PMID:10818257. |
gr73632-induced vocalisations were also markedly attenuated by the antidepressant drugs imipramine and fluoxetine (30 mg/kg), but not by the benzodiazepine anxiolytic diazepam (3 mg/kg) or the 5-ht(1a) agonist buspirone (10 mg/kg). |
2000-07-12 |
2023-08-12 |
mouse |
| P Afzelius, H J Nielse. Various functions of PBMC from colon cancer patients are not decreased compared to healthy blood donors. Cancer biotherapy & radiopharmaceuticals. vol 12. issue 2. 2000-06-29. PMID:10851450. |
we have therefore studied the proliferative responses of pbmc from colon cancer patients to pwm and tested the effect of immune modulating agents, such as serotonin, sumatriptan, and buspirone on these pbmc. |
2000-06-29 |
2023-08-12 |
Not clear |