All Relations between Azapirones and serotonin

Publication Sentence Publish Date Extraction Date Species
S Hjort. (-)-Pindolol, but not buspirone, potentiates the citalopram-induced rise in extracellular 5-hydroxytryptamine. European journal of pharmacology. vol 303. issue 3. 1996-12-11. PMID:8813565. (-)-pindolol (8 mg/kg s.c.) augmented the citalopram (5 mg/kg s.c.)-induced rise of extracellular 5-ht levels, whereas buspirone (5 mg/kg s.c.) failed to do so. 1996-12-11 2023-08-12 rat
S Hjort. (-)-Pindolol, but not buspirone, potentiates the citalopram-induced rise in extracellular 5-hydroxytryptamine. European journal of pharmacology. vol 303. issue 3. 1996-12-11. PMID:8813565. the lack of effect of buspirone in this model indicates that the clinically observed antidepressant augmentation action of buspirone is not mediated indirectly, via enhanced extracellular levels of 5-ht. 1996-12-11 2023-08-12 rat
E A Johnson, J L Fox, A J Azzar. The anxiolytic serotonin 5-HT1A receptor agonists buspirone, ipsapirone and gepirone are inhibitors of tyrosine hydroxylation in rat striatum. Behavioural brain research. vol 73. issue 1-2. 1996-12-04. PMID:8788529. the anxiolytic serotonin 5-ht1a receptor agonists buspirone, ipsapirone and gepirone are inhibitors of tyrosine hydroxylation in rat striatum. 1996-12-04 2023-08-12 rat
D F Connor, R J Steingar. A clinical approach to the pharmacotherapy of aggression in children and adolescents. Annals of the New York Academy of Sciences. vol 794. 1996-11-27. PMID:8853610. alternative medications, such as selective serotonin reuptake-inhibiting antidepressants, buspirone, lithium, anticonvulsants, opiate blocking agents, propranolol, nadolol, and clonidine, deserve more clinical research in pediatric aggression. 1996-11-27 2023-08-12 Not clear
I Korzeniewska, A Płaźni. Influence of serotonergic drugs on restraint stress induced analgesia. Polish journal of pharmacology. vol 47. issue 5. 1996-11-27. PMID:8868128. ritanserin, a 5-ht2a/2c receptor antagonist, ondansetron, a 5-ht3 receptor antagonist and citalopram, a selective serotonin re-uptake blocker increased the baseline pain threshold, whereas 8-oh-dpat, a full 5-ht1a receptor agonist and buspirone, a partial 5-ht1a receptor agonist expressing also high affinity towards dopaminergic d2 receptors, were without effect on pain perception and stress induced analgesia. 1996-11-27 2023-08-12 rat
Y Takada, T Urano, J Malyszko, A Takad. Changes in serotonergic measures in whole blood and various brain regions of rats administered with the 5-HT1A agonist tandospirone and/or exposed to electric foot-shock. Brain research bulletin. vol 40. issue 1. 1996-11-18. PMID:8722753. we studied the effects of foot-shock on tryptophan, serotonin [5-hydroxytryptamine (5-ht)], and its metabolite, 5-hydroxyindole acetic acid (5-hiaa) in whole blood and various brain regions of rats pretreated with tandospirone, a novel 5-ht1a receptor agonist. 1996-11-18 2023-08-12 rat
Y Takada, T Urano, J Malyszko, A Takad. Changes in serotonergic measures in whole blood and various brain regions of rats administered with the 5-HT1A agonist tandospirone and/or exposed to electric foot-shock. Brain research bulletin. vol 40. issue 1. 1996-11-18. PMID:8722753. the administration of tandospirone did not result in changes in serotonergic measures, but stress or stress plus the administration of tandospirone resulted in an increase in blood levels of tryptophan, 5-ht, and 5-hiaa. 1996-11-18 2023-08-12 rat
Y Takada, T Urano, J Malyszko, A Takad. Changes in serotonergic measures in whole blood and various brain regions of rats administered with the 5-HT1A agonist tandospirone and/or exposed to electric foot-shock. Brain research bulletin. vol 40. issue 1. 1996-11-18. PMID:8722753. the administration of tandospirone resulted in an increase in 5-ht levles in all brain regions except the cerebellum. 1996-11-18 2023-08-12 rat
Y Takada, T Urano, J Malyszko, A Takad. Changes in serotonergic measures in whole blood and various brain regions of rats administered with the 5-HT1A agonist tandospirone and/or exposed to electric foot-shock. Brain research bulletin. vol 40. issue 1. 1996-11-18. PMID:8722753. in rats given stress and tandospirone, 5-ht levels increased in the hypothalamus, midbrain, and cortex relative to controls. 1996-11-18 2023-08-12 rat
Y Takada, T Urano, J Malyszko, A Takad. Changes in serotonergic measures in whole blood and various brain regions of rats administered with the 5-HT1A agonist tandospirone and/or exposed to electric foot-shock. Brain research bulletin. vol 40. issue 1. 1996-11-18. PMID:8722753. in every part of the brain, the administration of tandospirone resulted in a decrease in the turnover rate of serotonin (5-hiaa/5-ht). 1996-11-18 2023-08-12 rat
Y Takada, T Urano, J Malyszko, A Takad. Changes in serotonergic measures in whole blood and various brain regions of rats administered with the 5-HT1A agonist tandospirone and/or exposed to electric foot-shock. Brain research bulletin. vol 40. issue 1. 1996-11-18. PMID:8722753. in the presence of stress, the administration of tandospirone resulted in a decrease in the turnover rate of serotonin in hypothalamus, hippocampus, and midbrain compared with controls and stress alone. 1996-11-18 2023-08-12 rat
Y Takada, T Urano, J Malyszko, A Takad. Changes in serotonergic measures in whole blood and various brain regions of rats administered with the 5-HT1A agonist tandospirone and/or exposed to electric foot-shock. Brain research bulletin. vol 40. issue 1. 1996-11-18. PMID:8722753. these results suggest that tandospirone may stimulate presynaptic receptors in the midbrain and inhibit the activity of monoamine oxidase, resulting in an increase in 5-ht levels in the serotonergic nerve terminals. 1996-11-18 2023-08-12 rat
J A Kim, M J Drus. Protective effects of maternal buspirone treatment on serotonin reuptake sites in ethanol-exposed offspring. Brain research. Developmental brain research. vol 92. issue 2. 1996-11-08. PMID:8738126. protective effects of maternal buspirone treatment on serotonin reuptake sites in ethanol-exposed offspring. 1996-11-08 2023-08-12 rat
J A Kim, M J Drus. Protective effects of maternal buspirone treatment on serotonin reuptake sites in ethanol-exposed offspring. Brain research. Developmental brain research. vol 92. issue 2. 1996-11-08. PMID:8738126. in addition, we attempted to overcome the potential negative impact of the ethanol-associated deficit of fetal 5-ht, by administering a 5-ht1a agonist, buspirone, to pregnant rats. 1996-11-08 2023-08-12 rat
J A Kim, M J Drus. Protective effects of maternal buspirone treatment on serotonin reuptake sites in ethanol-exposed offspring. Brain research. Developmental brain research. vol 92. issue 2. 1996-11-08. PMID:8738126. when [3h]citalopram binding was compared in the offspring of saline- and buspirone-treated dams, it appeared that maternal treatment with buspirone prevented or reversed most of the ethanol-associated developmental abnormalities in 5-ht reuptake sites. 1996-11-08 2023-08-12 rat
R F Anto. Neurobehavioural basis for the pharmacotherapy of alcoholism: current and future directions. Alcohol and alcoholism (Oxford, Oxfordshire). vol 31 Suppl 1. 1996-11-07. PMID:8737000. because there is considerable comorbidity between alcohol dependence, anxiety, and affective disorders, results from studies of medications used to treat these psychiatric disorders are also reviewed, including the 5-ht agonist buspirone and the noradrenergic agent desipramine. 1996-11-07 2023-08-12 human
J Strosznajder, M Chalimoniuk, M Samochock. Activation of serotonergic 5-HT1A receptor reduces Ca(2+)- and glutamatergic receptor-evoked arachidonic acid and No/cGMP release in adult hippocampus. Neurochemistry international. vol 28. issue 4. 1996-10-29. PMID:8740452. the agonist of 5-ht1a receptor, buspirone, in a way similar to serotonin itself, counteracts the ca(2+)- and also nmda receptor-evoked aa release and cgmp accumulation. 1996-10-29 2023-08-12 rat
J Strosznajder, M Chalimoniuk, M Samochock. Activation of serotonergic 5-HT1A receptor reduces Ca(2+)- and glutamatergic receptor-evoked arachidonic acid and No/cGMP release in adult hippocampus. Neurochemistry international. vol 28. issue 4. 1996-10-29. PMID:8740452. an antagonist of 5-ht1a receptor, nan-190, eliminates the effect of serotonin and buspirone on aa and no/cgmp liberation. 1996-10-29 2023-08-12 rat
D Charrier, M H Thiébo. Effects of psychotropic drugs on rat responding in an operant paradigm involving choice between delayed reinforcers. Pharmacology, biochemistry, and behavior. vol 54. issue 1. 1996-10-23. PMID:8728552. whatever the experimental parameters and stage of the learning, an acute administration of drugs able to reduce 5-ht neuronal activity (benzodiazepines; 5-ht1a receptor partial agonists: buspirone and mdl 73005ef) or enhance 5-ht transmission (5-ht reuptake inhibitors: indalpine and zimelidine; 5-ht1a receptor full agonist: 8-oh-dpat) failed significantly to alter choice strategy (decreased or increased preference for the large but delayed reward, respectively), as they did in other situations such as a t-maze procedure. 1996-10-23 2023-08-12 rat
L D Leake, M Koubanaki. Central and peripheral 5-HT receptors in the leech (Hirudo medicinalis) redefined. General pharmacology. vol 26. issue 8. 1996-10-23. PMID:8745160. all agonists induced hyperpolarisation of r cells: the order of their potency was 5-ht > 5-ct > 2-me 5ht > alpha-me-5-ht > > cgs-12066b = 5meot > papp > buspirone. 1996-10-23 2023-08-12 Not clear