| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria de Fátima Dos Santos Sampaio, Yara Bezerra de Paiva, Tuane Bazanella Sampaio, Messias Gonzaga Pereira, Norberto Cysne Coimbr. Therapeutic applicability of cannabidiol and other phytocannabinoids in epilepsy, multiple sclerosis and Parkinson's disease and in comorbidity with psychiatric disorders. Basic & clinical pharmacology & toxicology. 2024-03-13. PMID:38477419. |
studies have demonstrated the neuroprotective effect of cannabidiol (cbd) and other cannabis sativa l. derivatives on diseases of the central nervous system caused by their direct or indirect interaction with endocannabinoid system-related receptors and other molecular targets, such as the 5-ht |
2024-03-13 |
2024-03-15 |
Not clear |
| Yu-Meng Liu, Jin-Cao Li, Yong-Fang Gu, Ren-Hong Qiu, Jia-Ying Huang, Rui Xue, Shuo Li, Yang Zhang, Kuo Zhang, You-Zhi Zhan. Cannabidiol Exerts Sedative and Hypnotic Effects in Normal and Insomnia Model Mice Through Activation of 5-HT Neurochemical research. 2024-01-31. PMID:38296858. |
cannabidiol exerts sedative and hypnotic effects in normal and insomnia model mice through activation of 5-ht cannabis sativa has been used for improving sleep for long history. |
2024-01-31 |
2024-02-03 |
mouse |
| Robert C Barnes, Satish Banjara, Melissa C McHann, Sharilyn Almodovar, Angela N Henderson-Redmond, Daniel J Morgan, Isabel Castro-Piedras, Josée Guindo. Assessing dose and sex dependent antinociceptive effects of cannabidiol and amitriptyline, alone and in combination, and exploring mechanism of action involving serotonin 1A receptors. The Journal of pharmacology and experimental therapeutics. 2023-12-21. PMID:38129125. |
these results suggest a role for serotonin and sex in mediating cannabidiol and amitriptyline-induced antinociception in inflammatory pain. |
2023-12-21 |
2023-12-24 |
mouse |
| Robert C Barnes, Satish Banjara, Melissa C McHann, Sharilyn Almodovar, Angela N Henderson-Redmond, Daniel J Morgan, Isabel Castro-Piedras, Josée Guindo. Assessing dose and sex dependent antinociceptive effects of cannabidiol and amitriptyline, alone and in combination, and exploring mechanism of action involving serotonin 1A receptors. The Journal of pharmacology and experimental therapeutics. 2023-12-21. PMID:38129125. |
assessing dose and sex dependent antinociceptive effects of cannabidiol and amitriptyline, alone and in combination, and exploring mechanism of action involving serotonin 1a receptors. |
2023-12-21 |
2023-12-24 |
mouse |
| Zohaib Nadeem, Chaston Wu, Sophie Burke, Stephen Parke. Serotonin syndrome and cannabis: A case report. Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists. 2023-12-07. PMID:38058145. |
serotonin syndrome and cannabis: a case report. |
2023-12-07 |
2023-12-10 |
Not clear |
| Jurga Bernatoniene, Arunas Sciupokas, Dalia Marija Kopustinskiene, Kestutis Petrikoni. Novel Drug Targets and Emerging Pharmacotherapies in Neuropathic Pain. Pharmaceutics. vol 15. issue 7. 2023-07-29. PMID:37513986. |
current pharmacotherapies, including tricyclic antidepressants, gabapentinoids, and serotonin norepinephrine re-uptake inhibitors, are discussed, as are emerging treatments, such as ambroxol, cannabidiol, and n-acetyl-l-cysteine. |
2023-07-29 |
2023-08-14 |
Not clear |
| Danielle Diniz Aguiar, Cristina da Costa Oliveira, Flávia Cristina Sousa Fonseca, Douglas Lamounier de Almeida, William Valadares Campos Pereira, Francisco Silveira Guimarães, Andrea Castro Perez, Igor Dimitri Gama Duarte, Thiago Roberto Lima Romer. Peripherally injected canabidiol reduces neuropathic pain in mice: Role of the 5-HT Biochemical and biophysical research communications. vol 660. 2023-04-17. PMID:37068389. |
peripherally injected canabidiol reduces neuropathic pain in mice: role of the 5-ht cannabidiol (cbd) is the most abundant non-psychoactive component found in plants of the genus cannabis. |
2023-04-17 |
2023-08-14 |
mouse |
| Jaqueline M Franzen, Isabel Werle, Felipe Vanz, Bruno Biscaia de Oliveira, Laura Maria Martins Nascimento, Francisco S Guimarães, Leandro J Bertogli. Cannabidiol attenuates fear memory expression in female rats via hippocampal 5-HT Neuropharmacology. 2022-11-05. PMID:36334768. |
cannabidiol attenuates fear memory expression in female rats via hippocampal 5-ht growing evidence from male rodent and human studies suggests that cannabidiol (cbd) modulates the expression of aversive memories and anxiety-related responses. |
2022-11-05 |
2023-08-14 |
human |
| Lígia Renata Rodrigues Tavares, Daniela Baptista-de-Souza, Lucas Canto-de-Souza, Cleopatra da Silva Planeta, Francisco Silveira Guimarães, Ricardo Luiz Nunes-de-Souza, Azair Canto-de-Souz. The Reversal of Empathy-Induced Hypernociception in Male Mice by Intra-Amygdala Administration of Midazolam and Cannabidiol Depends on 5-HT Cannabis and cannabinoid research. 2022-09-14. PMID:36103283. |
the reversal of empathy-induced hypernociception in male mice by intra-amygdala administration of midazolam and cannabidiol depends on 5-ht |
2022-09-14 |
2023-08-14 |
mouse |
| Faiza Boukerche, Mostafa Zakaria Khalil, Daisy Vyas Shirk, Jasmin Gange Lagma. Serotonin Syndrome Misdiagnosed in a Patient Who Used a Cannabis Dab Pen. The primary care companion for CNS disorders. vol 24. issue 2. 2022-04-14. PMID:35421906. |
serotonin syndrome misdiagnosed in a patient who used a cannabis dab pen. |
2022-04-14 |
2023-08-13 |
Not clear |
| R B Malvestio, P Medeiros, S E Negrini-Ferrari, M Oliveira-Silva, A C Medeiros, C M Padovan, L Luongo, S Maione, N C Coimbra, R L de Freita. Cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: The role of medial prefrontal cortex 5-HT Brain research bulletin. vol 174. 2021-12-10. PMID:34192579. |
cannabidiol in the prelimbic cortex modulates the comorbid condition between the chronic neuropathic pain and depression-like behaviour in rats: the role of medial prefrontal cortex 5-ht the prelimbic division (prl) of the medial prefrontal cortex (mpfc) is a cerebral division that is putatively implicated in the chronic pain and depression. |
2021-12-10 |
2023-08-13 |
rat |
| Emily Nash, Darren M Roberts, Nazila Jamshid. Reverse Takotsubo Cardiomyopathy Precipitated by Chronic Cocaine and Cannabis Use. Cardiovascular toxicology. vol 21. issue 12. 2021-10-19. PMID:34426937. |
in this case, multiple insults including severe headache, cannabis hyperemesis and cocaine and methamphetamine-induced serotonin toxicity culminated in a drug-induced seizure which led to catecholamine cardiotoxicity resulting in rtc. |
2021-10-19 |
2023-08-13 |
Not clear |
| Malene J Petersen, Sofie O Bergien, Dan Staer. A systematic review of possible interactions for herbal medicines and dietary supplements used concomitantly with disease-modifying or symptom-alleviating multiple sclerosis drugs. Phytotherapy research : PTR. vol 35. issue 7. 2021-09-28. PMID:33624893. |
combinations between chronic cannabis use and selective serotonin reuptake inhibitors or non-steroidal antiinflammatory drugs should be carefully monitored, whereas no significant evidence for drug-interactions between conventional ms-drugs and ginger, cranberry, vitamin d, fatty acids, turmeric, probiotics or glucosamine was found. |
2021-09-28 |
2023-08-13 |
Not clear |
| Coralie Berthoux, Al Mahdy Hamieh, Angelina Rogliardo, Emilie L Doucet, Camille Coudert, Fabrice Ango, Katarzyna Grychowska, Séverine Chaumont-Dubel, Pawel Zajdel, Rafael Maldonado, Joël Bockaert, Philippe Marin, Carine Bécame. Early 5-HT EMBO molecular medicine. vol 12. issue 5. 2021-08-18. PMID:32329240. |
early 5-ht cannabis abuse during adolescence confers an increased risk for developing later in life cognitive deficits reminiscent of those observed in schizophrenia, suggesting common pathological mechanisms that remain poorly characterized. |
2021-08-18 |
2023-08-13 |
Not clear |
| Samuel E Vaughn, Jeffrey R Strawn, Ethan A Poweleit, Mayur Sarangdhar, Laura B Ramse. The Impact of Marijuana on Antidepressant Treatment in Adolescents: Clinical and Pharmacologic Considerations. Journal of personalized medicine. vol 11. issue 7. 2021-07-27. PMID:34209709. |
the neuropharmacology of marijuana, including its effects on selective serotonin reuptake inhibitor (ssri)/antidepressant metabolism and the subsequent response and tolerability in youth, has received limited attention. |
2021-07-27 |
2023-08-13 |
Not clear |
| Amna C Mazeh, James A Angus, Christine E Wrigh. Cannabidiol selectively inhibits the contraction of rat small resistance arteries: Possible role for CGRP and voltage-gated calcium channels. European journal of pharmacology. vol 891. 2021-05-19. PMID:33275960. |
isolated small or large arteries were incubated with cannabidiol (0.3-3 μm) or vehicle and concentration-contraction response curves were completed to various agents, including endothelin-1, arginine vasopressin, methoxamine, 5-ht, α-methyl 5-ht and u46619. |
2021-05-19 |
2023-08-13 |
rat |
| Andrew Salzwedel, Gang Chen, Yuanyuan Chen, Karen Grewen, Wei Ga. Functional dissection of prenatal drug effects on baby brain and behavioral development. Human brain mapping. vol 41. issue 17. 2021-05-17. PMID:32779835. |
in this study, based on a large sample of 133 human neonates and leveraging a novel linear mixed-effect model designed for intersubject variability analyses, we studied the effects of six prenatally exposed drugs (i.e., nicotine, alcohol, selective serotonin reuptake inhibitor, marijuana, cocaine, and opioids) on neonatal whole-brain functional organization and compared them with five other critical nondrug variables (i.e., gestational age at birth/scan, sex, birth weight, and maternal depression). |
2021-05-17 |
2023-08-13 |
human |
| Melkamu Alemu Abame, Yang He, Song Wu, Zhifei Xie, Jian Zhang, Xudong Gong, Chunhui Wu, Jingshan She. Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus. Neuroscience letters. vol 744. 2021-04-30. PMID:33388355. |
chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus. |
2021-04-30 |
2023-08-13 |
mouse |
| Ewa Galaj, Guo-Hua Bi, Hong-Ju Yang, Zheng-Xiong X. Cannabidiol attenuates the rewarding effects of cocaine in rats by CB2, 5-HT Neuropharmacology. vol 167. 2021-04-23. PMID:31437433. |
cannabidiol attenuates the rewarding effects of cocaine in rats by cb2, 5-ht cocaine abuse continues to be a serious health problem worldwide. |
2021-04-23 |
2023-08-13 |
rat |
| Philippe A Melas, Maria Scherma, Walter Fratta, Carlo Cifani, Paola Fadd. Cannabidiol as a Potential Treatment for Anxiety and Mood Disorders: Molecular Targets and Epigenetic Insights from Preclinical Research. International journal of molecular sciences. vol 22. issue 4. 2021-04-15. PMID:33668469. |
cannabidiol (cbd) is the most abundant non-psychoactive component of cannabis; it displays a very low affinity for cannabinoid receptors, facilitates endocannabinoid signaling by inhibiting the hydrolysis of anandamide, and stimulates both transient receptor potential vanilloid 1 and 2 and serotonin type 1a receptors. |
2021-04-15 |
2023-08-13 |
Not clear |