| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jo Sourbron, Lieven Laga. Fenfluramine: a plethora of mechanisms? Frontiers in pharmacology. vol 14. 2023-05-30. PMID:37251322. |
the antiseizure medication (asm) fenfluramine is an effective treatment for reducing seizure frequency, ameliorating comorbidities, and potentially reducing risk of sudden unexpected death in epilepsy (sudep) in patients with dravet syndrome and lennox-gastaut syndrome, among other rare epilepsies. |
2023-05-30 |
2023-08-14 |
Not clear |
| Antonio Gil-Nagel, Mercè Falip, Rocío Sánchez-Carpintero, María Reyes Abad-Sazatornil, José Luis Poveda, José Ángel Aibar, Elena Cardenal-Muñoz, Luis Miguel Aras, Rosa Sánchez, Arantxa Sancho-López, José Luis Trillo-Mata, María Torrejón, Alicia Gi. The contribution of fenfluramine to the treatment of Dravet syndrome in Spain through Multi-Criteria Decision Analysis. Epilepsy & behavior : E&B. vol 132. 2022-05-19. PMID:35588562. |
fenfluramine decreases seizure frequency, prolongs periods of seizure freedom potentially helping to reduce risk of sudden unexpected death in epilepsy (sudep) and improves patient cognitive abilities positively impacting on patients' quality of life (qol). |
2022-05-19 |
2023-08-13 |
Not clear |
| J Helen Cross, Bradley S Galer, Antonio Gil-Nagel, Orrin Devinsky, Berten Ceulemans, Lieven Lagae, An-Sofie Schoonjans, Elizabeth Donner, Elaine Wirrell, Sanjeev Kothare, Anupam Agarwal, Michael Lock, Arnold R Gammaiton. Impact of fenfluramine on the expected SUDEP mortality rates in patients with Dravet syndrome. Seizure. vol 93. 2021-12-08. PMID:34768178. |
to assess the impact of fenfluramine (ffa) on the expected mortality incidence, including sudden unexpected death in epilepsy (sudep), in persons with dravet syndrome (ds). |
2021-12-08 |
2023-08-13 |
Not clear |
| Srinivasan Tupal, Carl L Faingol. Serotonin 5-HT Epilepsy research. vol 177. 2021-11-01. PMID:34601387. |
serotonin 5-ht our previous study showed that the recently approved anticonvulsant drug, fenfluramine, which enhances the release of serotonin (5-hydroxytryptamine, 5-ht) in the brain, prevents seizure-induced respiratory arrest (s-ira) in the dba/1 mouse model of sudden unexpected death in epilepsy (sudep). |
2021-11-01 |
2023-08-13 |
mouse |