| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qunhui Yang, Jiancheng Yang, Gaofeng Wu, Ying Feng, Qiufeng Lv, Shumei Lin, Jianmin H. Effects of taurine on myocardial cGMP/cAMP ratio, antioxidant ability, and ultrastructure in cardiac hypertrophy rats induced by isoproterenol. Advances in experimental medicine and biology. vol 776. 2013-06-12. PMID:23392885. |
effects of taurine on myocardial cgmp/camp ratio, antioxidant ability, and ultrastructure in cardiac hypertrophy rats induced by isoproterenol. |
2013-06-12 |
2023-08-12 |
human |
| Qunhui Yang, Jiancheng Yang, Gaofeng Wu, Ying Feng, Qiufeng Lv, Shumei Lin, Jianmin H. Effects of taurine on myocardial cGMP/cAMP ratio, antioxidant ability, and ultrastructure in cardiac hypertrophy rats induced by isoproterenol. Advances in experimental medicine and biology. vol 776. 2013-06-12. PMID:23392885. |
to investigate the preventive effects of taurine on cardiac hypertrophy in rats, myocardial injury was established by hypodermic injection of isoprenaline (iso) (10 mg/kg d) for 7 days. |
2013-06-12 |
2023-08-12 |
human |
| Qunhui Yang, Jiancheng Yang, Gaofeng Wu, Ying Feng, Qiufeng Lv, Shumei Lin, Jianmin H. Effects of taurine on myocardial cGMP/cAMP ratio, antioxidant ability, and ultrastructure in cardiac hypertrophy rats induced by isoproterenol. Advances in experimental medicine and biology. vol 776. 2013-06-12. PMID:23392885. |
in conclusion, the present study demonstrated that taurine could inhibit the injury induced by iso by increasing myocardial negative inotropic effect and antioxidant ability, decreasing the hypertrophic response to isoproterenol and protecting the integrity of -myocardial ultrastructure, decreasing myocardial leak of ck-mb. |
2013-06-12 |
2023-08-12 |
human |
| Ming-Zi Chen, Qing-Ting Bu, Shu-Chao Pang, Feng-Lan Li, Mei-Na Sun, Er-Fu Chu, Hui L. Tetrodotoxin attenuates isoproterenol-induced hypertrophy in H9c2 rat cardiac myocytes. Molecular and cellular biochemistry. vol 371. issue 1-2. 2013-05-17. PMID:22941212. |
the present study was carried out to determine whether the reversible sodium channel blocker tetrodotoxin (ttx) exerts a direct anti-hypertrophic effect on isoproterenol (iso)-induced cell hypertrophy and find the underlying mechanism that regulate [na(+)]( i ). |
2013-05-17 |
2023-08-12 |
rat |
| B M Patel, S S Agarwal, S V Bhadad. Perindopril protects against streptozotocin-induced hyperglycemic myocardial damage/alterations. Human & experimental toxicology. vol 31. issue 11. 2013-04-30. PMID:22653691. |
we studied the effect of perindopril (1 mg/kg/d orally [po]) on cardiovascular complications in neonatal model of rats, which was induced by administering stz (90 mg/kg, intraperitoneally [ip]), in 5-d-old wistar rats and cardiac hypertrophy induced by isoprenaline (iso; 5 mg/kg, ip) for 10 d. various biochemical, cardiac, and hemodynamic parameters were measured at the end of 8 weeks of treatment in diabetes model and 10 d in hypertrophy model. |
2013-04-30 |
2023-08-12 |
rat |
| Vinodkumar B Pillai, Nagalingam R Sundaresan, Gene Kim, Sadhana Samant, Liliana Moreno-Vinasco, Joe G N Garcia, Mahesh P Gupt. Nampt secreted from cardiomyocytes promotes development of cardiac hypertrophy and adverse ventricular remodeling. American journal of physiology. Heart and circulatory physiology. vol 304. issue 3. 2013-03-22. PMID:23203961. |
whereas nampt(+/-) mice were protected against agonist (isoproterenol and angiotensin ii)-induced hypertrophy, nampt transgenic mice spontaneously developed cardiac hypertrophy at 6 mo of age. |
2013-03-22 |
2023-08-12 |
mouse |
| Monica Flores-Muñoz, Bruno M D C Godinho, Abdulaziz Almalik, Stuart A Nickli. Adenoviral delivery of angiotensin-(1-7) or angiotensin-(1-9) inhibits cardiomyocyte hypertrophy via the mas or angiotensin type 2 receptor. PloS one. vol 7. issue 9. 2013-03-06. PMID:23029101. |
here, we have engineered adenoviral vectors expressing fusion proteins which release ang-(1-7) [radang-(1-7)] or ang-(1-9) [radang-(1-9)] and compared their effects on cardiomyocyte hypertrophy in rat h9c2 cardiomyocytes or primary adult rabbit cardiomyocytes, stimulated with angiotensin ii, isoproterenol or arg-vasopressin. |
2013-03-06 |
2023-08-12 |
rat |
| Beatriz Martín-Fernández, Natalia de las Heras, María Miana, Sandra Ballesteros, María Valero-Muñoz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Laher. Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. Experimental physiology. vol 97. issue 6. 2013-01-18. PMID:22327331. |
spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. |
2013-01-18 |
2023-08-12 |
rat |
| Beatriz Martín-Fernández, Natalia de las Heras, María Miana, Sandra Ballesteros, María Valero-Muñoz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Laher. Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. Experimental physiology. vol 97. issue 6. 2013-01-18. PMID:22327331. |
persistent β-adrenergic receptor stimulation with isoproterenol is associated with cardiac hypertrophy as well as cardiac synthesis of angiotensin ii. |
2013-01-18 |
2023-08-12 |
rat |
| Beatriz Martín-Fernández, Natalia de las Heras, María Miana, Sandra Ballesteros, María Valero-Muñoz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Laher. Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. Experimental physiology. vol 97. issue 6. 2013-01-18. PMID:22327331. |
isoproterenol treatment induced cardiac hypertrophy and increased collagen content, both of which were normalized by spironolactone treatment. |
2013-01-18 |
2023-08-12 |
rat |
| Beatriz Martín-Fernández, Natalia de las Heras, María Miana, Sandra Ballesteros, María Valero-Muñoz, Dalton Vassallo, Ana Paula Davel, Luciana Venturini Rossoni, Victoria Cachofeiro, Vicente Laher. Spironolactone prevents alterations associated with cardiac hypertrophy produced by isoproterenol in rats: involvement of serum- and glucocorticoid-regulated kinase type 1. Experimental physiology. vol 97. issue 6. 2013-01-18. PMID:22327331. |
the observed reduction of the principal mediator of aldosterone cellular actions, sgk-1, by spironolactone in hearts from isoproterenol-treated rats suggests a role of mineralocorticoids in the cardiac hypertrophy, fibrosis, inflammation, oxidation and diastolic dysfunction induced by isoproterenol treatment in rats. |
2013-01-18 |
2023-08-12 |
rat |
| Subir Kumar Maulik, Pankaj Prabhakar, Amit Kumar Dinda, Sandeep Set. Genistein prevents isoproterenol-induced cardiac hypertrophy in rats. Canadian journal of physiology and pharmacology. vol 90. issue 8. 2013-01-11. PMID:22808991. |
isoproterenol (5 mg·(kg body weight)(-1)) was injected subcutaneously once daily for 14 days to induced cardiac hypertrophy. |
2013-01-11 |
2023-08-12 |
rat |
| Marco Fabricio Dias-Peixoto, Anderson J Ferreira, Pedro W M Almeida, Vinícius B A Braga, Danielle C O Coutinho, Dirceu S Melo, Ary Gomes Filho, Marcos B Melo, Leonardo Greco, Maria José Campagnole-Santos, Ricardo F Lima, Robson A S Santos, Silvia Guatimosi. The cardiac expression of Mas receptor is responsive to different physiological and pathological stimuli. Peptides. vol 35. issue 2. 2012-11-19. PMID:22504011. |
on the other hand, cardiac hypertrophy and damage elicited by isoproterenol treatment led to a reduction in mas expression. |
2012-11-19 |
2023-08-12 |
rat |
| Catherine L Passariello, Davide Gottardi, Silvia Cetrullo, Maddalena Zini, Gabriele Campana, Benedetta Tantini, Carla Pignatti, Flavio Flamigni, Carlo Guarnieri, Claudio M Caldarera, Claudio Stefanell. Evidence that AMP-activated protein kinase can negatively modulate ornithine decarboxylase activity in cardiac myoblasts. Biochimica et biophysica acta. vol 1823. issue 4. 2012-11-09. PMID:22230191. |
the responses of amp-activated protein kinase (ampk) and ornithine decarboxylase (odc) to isoproterenol have been examined in h9c2 cardiomyoblasts, ampk represents the link between cell growth and energy availability whereas odc, the key enzyme in polyamine biosynthesis, is essential for all growth processes and it is thought to have a role in the development of cardiac hypertrophy. |
2012-11-09 |
2023-08-12 |
Not clear |
| Daisuke Takeshita, Chikako Nakajima-Takenaka, Juichiro Shimizu, Hiroshi Hattori, Tamiji Nakashima, Akio Kikuta, Hiroko Matsuyoshi, Miyako Takak. Effects of formaldehyde on cardiovascular system in in situ rat hearts. Basic & clinical pharmacology & toxicology. vol 105. issue 4. 2012-11-01. PMID:19558560. |
the aim of the present study was to examine the effects of formaldehyde solution on rat left ventricular function and compare it with those in hypertrophic hearts treated with isoproterenol by pressure-volume measurements with the catheter method. |
2012-11-01 |
2023-08-12 |
rat |
| Julie A Wolfram, Anna Liner, Sandy L Richardson, Xiongwei Zhu, Mark A Smith, Brian D Hoit, Hyoung-Gon Le. The role of E2F1 in the development of hypertrophic cardiomyopathy. International journal of clinical and experimental pathology. vol 4. issue 5. 2012-10-31. PMID:21738823. |
accordingly, we tested the hypothesis that blocking the e2f1-mediated signal transduction pathway prevents cardiac hypertrophy by treating e2f1 knockout mice (e2f1-/-) with either isoproterenol (iso) or angiotensin ii (ang). |
2012-10-31 |
2023-08-12 |
mouse |
| Thomas J Larocca, Dongtak Jeong, Erik Kohlbrenner, Ahyoung Lee, Jiqiu Chen, Roger J Hajjar, Sima T Tarzam. CXCR4 gene transfer prevents pressure overload induced heart failure. Journal of molecular and cellular cardiology. vol 53. issue 2. 2012-10-31. PMID:22668785. |
in isolated adult rat cardiac myocytes, cxcl12 treatment prevented isoproterenol induced hypertrophy and interrupted the calcineurin/nfat pathway. |
2012-10-31 |
2023-08-12 |
mouse |
| Rashmi Choudhary, K P Mishra, C Subramanya. Prevention of isoproterenol-induced cardiac hypertrophy by eugenol, an antioxidant. Indian journal of clinical biochemistry : IJCB. vol 21. issue 2. 2012-10-30. PMID:23105625. |
intraperitoneal administration of isoproterenol (1 mg/kg body wt/day for 10 days) induced cardiac hypertrophy with increased heart weight and enhanced apoptosis of myocytes concomitant with accumulation of reactive oxygen species, decreased glutathione contents, increased activities of calcineurin and protein kinase c in ventricular tissue. |
2012-10-30 |
2023-08-12 |
rat |
| Rashmi Choudhary, K P Mishra, C Subramanya. Prevention of isoproterenol-induced cardiac hypertrophy by eugenol, an antioxidant. Indian journal of clinical biochemistry : IJCB. vol 21. issue 2. 2012-10-30. PMID:23105625. |
administering eugenol for 3 days (1 mg/kg body wt/twice a day), followed by combined administration of isoproterenol and eugenol resulted in significant reversal of cardiac hypertrophy and restoration of above changes. |
2012-10-30 |
2023-08-12 |
rat |
| Christopher D Haines, Pamela A Harvey, Leslie A Leinwan. Estrogens mediate cardiac hypertrophy in a stimulus-dependent manner. Endocrinology. vol 153. issue 9. 2012-10-29. PMID:22759381. |
when challenged with the pathological stimulus, isoproterenol, arko females developed 2-fold more hypertrophy than wild-type females. |
2012-10-29 |
2023-08-12 |
mouse |