| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bernard Abrenica, Mohamed AlShaaban, Michael P Czubry. The A-kinase anchor protein AKAP121 is a negative regulator of cardiomyocyte hypertrophy. Journal of molecular and cellular cardiology vol 46 issue 5 2009 19358331 |
we also demonstrate that over-expression of akap121 in cardiac myocytes reduces basal cell size, and blocks hypertrophy induced by isoproterenol, indicating that akap121 negatively regulates the hypertrophic process. |
2009-06-17 |
2023-01-25 |
rat |
| Kyuho Jeong, Hayeong Kwon, Chanhee Min, Yunbae Pa. Modulation of the caveolin-3 localization to caveolae and STAT3 to mitochondria by catecholamine-induced cardiac hypertrophy in H9c2 cardiomyoblasts. Experimental & molecular medicine vol 41 issue 4 2009 19299911 |
we investigated the effect of phenylephrine (pe)- and isoproterenol (iso)-induced cardiac hypertrophy on subcellular localization and expression of caveolin-3 and stat3 in h9c2 cardiomyoblast cells. |
2009-06-02 |
2023-01-25 |
Not clear |
| M Anderson, D Moore, Df Larso. Comparison of isoproterenol and dobutamine in the induction of cardiac hypertrophy and fibrosis. Perfusion vol 23 issue 4 2009 19181756 |
comparison of isoproterenol and dobutamine in the induction of cardiac hypertrophy and fibrosis. |
2009-05-19 |
2023-01-25 |
mouse |
| M Anderson, D Moore, Df Larso. Comparison of isoproterenol and dobutamine in the induction of cardiac hypertrophy and fibrosis. Perfusion vol 23 issue 4 2009 19181756 |
isoproterenol (iso) was a clinical therapeutic that is now used as a research means for the induction of cardiac hypertrophy. |
2009-05-19 |
2023-01-25 |
mouse |
| A C Issy, C A da Silva, F S Guimar\\xc3\\xa3es, E A Del Be. Different role of isoproterenol and NOS inhibitors on salivary ducts of rats. Micron (Oxford, England : 1993) vol 40 issue 3 2009 19167231 |
chronic treatment with isoproterenol, a beta receptor agonist, stimulates the release of no from acinar cells and induces salivary gland hypertrophy. |
2009-04-30 |
2023-01-25 |
rat |
| Daniel R Higazi, Claire J Fearnley, Faye M Drawnel, Amarnath Talasila, Elaine M Corps, Oliver Ritter, Fraser McDonald, Katsuhiko Mikoshiba, Martin D Bootman, H Llewelyn Roderic. Endothelin-1-stimulated InsP3-induced Ca2+ release is a nexus for hypertrophic signaling in cardiac myocytes. Molecular cell vol 33 issue 4 2009 19250908 |
moreover, we found that activation of the cna/nfat pathway and hypertrophy by isoproterenol and bayk8644, which enhance global ca(2+) fluxes, was also dependent on iicr and nuclear ca(2+) elevations. |
2009-04-06 |
2023-01-25 |
Not clear |
| Yun-He Liu, Martin D'Ambrosio, Tang-dong Liao, Hongmei Peng, Nour-Eddine Rhaleb, Umesh Sharma, Sabine Andr\\xc3\\xa9, Hans-J Gabius, Oscar A Carreter. N-acetyl-seryl-aspartyl-lysyl-proline prevents cardiac remodeling and dysfunction induced by galectin-3, a mammalian adhesion/growth-regulatory lectin. American journal of physiology. Heart and circulatory physiology vol 296 issue 2 2009 19098114 |
we found that, in the left ventricle, gal-3 1) enhanced macrophage and mast cell infiltration, increased cardiac interstitial and perivascular fibrosis, and causes cardiac hypertrophy; 2) increased tgf-beta expression and smad3 phosphorylation; and 3) decreased negative change in pressure over time response to isoproterenol challenge, ratio of early left ventricular filling phase to atrial contraction phase, and left ventricular ejection fraction. |
2009-03-12 |
2023-01-25 |
rat |
| Jun Cai, Fang-Fang Yi, Long Yang, Di-Fei Shen, Qinling Yang, Ankang Li, Asish K Ghosh, Zhou-Yan Bian, Ling Yan, Qi-Zhu Tang, Hongliang Li, Xin-Chun Yan. Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling. Hypertension (Dallas, Tex. : 1979) vol 53 issue 3 2009 19204184 |
we investigated the effect of cardiac overexpression of rat ralt on cardiac hypertrophy induced by angiotensin ii and isoproterenol in ralt transgenic mice and wild-type littermates. |
2009-03-09 |
2023-01-25 |
rat |
| T Yar, M El-Hariri, M N El-Bahai, A O Bamos. Effects of Nigella sativa supplementation for one month on cardiac reserve in rats. Indian journal of physiology and pharmacology vol 52 issue 2 2009 19130857 |
the observed nigella-induced cardiac hypertrophy was associated with an increase in the baseline cardiac inotropic properties as well as the maximal peak tension generation upon progressive cardiac stress by isoproterenol infusion. |
2009-01-22 |
2023-01-25 |
rat |
| Hae Jin Kee, Gwang Hyeon Eom, Hosouk Joung, Sera Shin, Ju-Ryoung Kim, Young Kuk Cho, Nakwon Choe, Bo-Woong Sim, Daewoong Jo, Myung Ho Jeong, Kyung Keun Kim, Jeong-Sun Seo, Hyun Koo. Activation of histone deacetylase 2 by inducible heat shock protein 70 in cardiac hypertrophy. Circulation research vol 103 issue 11 2008 18849323 |
cardiac hypertrophy was introduced by aortic banding, by infusion of isoproterenol or angiotensin ii, or by swimming. |
2008-12-31 |
2023-01-25 |
mouse |
| Evelyn T Flanagan, Maria M Buckley, Claire M Aherne, Fredolin Lainis, Munavvar Sattar, Edward J John. Impact of cardiac hypertrophy on arterial and cardiopulmonary baroreflex control of renal sympathetic nerve activity in anaesthetized rats. Experimental physiology vol 93 issue 9 2008 18487313 |
this study aimed to quantify the effect of cardiac hypertrophy induced with isoprenaline and caffeine on reflex regulation of renal sympathetic nerve activity by the arterial and cardiopulmonary baroreceptors. |
2008-12-12 |
2023-01-24 |
rat |
| Guoqiang Wu, Hongxin Wang, Jing Yang, Yuhong Yang, Chunna Liu, Li Jing, Tak Ming Won. kappa-Opioid receptor stimulation inhibits augmentation of Ca(2+) transient and hypertrophy induced by isoprenaline in neonatal rat ventricular myocytes - Role of CaMKIIdelta(B). European journal of pharmacology vol 595 issue 1-3 2008 18721804 |
kappa-opioid receptor stimulation inhibits augmentation of ca(2+) transient and hypertrophy induced by isoprenaline in neonatal rat ventricular myocytes - role of camkiidelta(b). |
2008-11-18 |
2023-01-25 |
rat |
| Guoqiang Wu, Hongxin Wang, Jing Yang, Yuhong Yang, Chunna Liu, Li Jing, Tak Ming Won. kappa-Opioid receptor stimulation inhibits augmentation of Ca(2+) transient and hypertrophy induced by isoprenaline in neonatal rat ventricular myocytes - Role of CaMKIIdelta(B). European journal of pharmacology vol 595 issue 1-3 2008 18721804 |
we determined the effects of trans-(+/-)-3,4-dichloro-n-methyl-n-[2-(1-pyrrolidinyl)-cyclohexyl]-benzeneacetamid methanesulfonate salt (u50,488h), a selective kappa-opioid receptor agonist, on the enhancement of spontaneous ca(2+) transients and the induction of hypertrophy by isoprenaline, a beta-adrenoceptor agonist, in cultured neonatal ventricular myocytes. |
2008-11-18 |
2023-01-25 |
rat |
| Guoqiang Wu, Hongxin Wang, Jing Yang, Yuhong Yang, Chunna Liu, Li Jing, Tak Ming Won. kappa-Opioid receptor stimulation inhibits augmentation of Ca(2+) transient and hypertrophy induced by isoprenaline in neonatal rat ventricular myocytes - Role of CaMKIIdelta(B). European journal of pharmacology vol 595 issue 1-3 2008 18721804 |
kappa-opioid receptor stimulation suppressed the stimulatory effect of isoprenaline on ca(2+) transients and cardiac hypertrophy, as did kn93, propranalol and verapamil. |
2008-11-18 |
2023-01-25 |
rat |
| Elham Zarrinpashneh, Christophe Beauloye, Audrey Ginion, Anne-Catherine Pouleur, Xavier Havaux, Louis Hue, Benoit Viollet, Jean-Louis Vanoverschelde, Luc Bertran. AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol. Biochemical and biophysical research communications vol 376 issue 4 2008 18812163 |
ampkalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol. |
2008-11-13 |
2023-01-25 |
mouse |
| Elham Zarrinpashneh, Christophe Beauloye, Audrey Ginion, Anne-Catherine Pouleur, Xavier Havaux, Louis Hue, Benoit Viollet, Jean-Louis Vanoverschelde, Luc Bertran. AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol. Biochemical and biophysical research communications vol 376 issue 4 2008 18812163 |
we investigated the contribution of ampkalpha2 in the control of cardiac hypertrophy by using ampkalpha2-/- mice submitted to isoproterenol. |
2008-11-13 |
2023-01-25 |
mouse |
| Stevan P Tofovic, Xinchen Zhang, Hong Zhu, Edwin K Jackson, Olga Rafikova, Gordana Petrusevsk. 2-Ethoxyestradiol is antimitogenic and attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling. Vascular pharmacology vol 48 issue 4-6 2008 18373958 |
the goals of this study were: 1) to compare the effects of e2, 2-me and 2-ee on proliferation of human pulmonary artery endothelial (hpaec) and smooth muscle cells (hpasmc) and lung fibroblasts (hlf); 2) to examine the effects of 2-me, its metabolic precursor 2-hydroxyestradiol (2-he) and 2-ee on isoproterenol (iso)-induced cardiac hypertrophy in male rats; and 3) to investigate in male rats the effects of 2-ee (10 mug/kg/h via osmotic pump) on the development of monocrotaline (mct; 60 mg/kg i.p. |
2008-10-27 |
2023-01-24 |
rat |
| Kazuhiko Hanada, Kazuhiko Asari, Masako Saito, Jun-Ichi Kawana, Mitsuo Mita, Hiroyasu Ogat. Comparison of pharmacodynamics between carvedilol and metoprolol in rats with isoproterenol-induced cardiac hypertrophy: effects of carvedilol enantiomers. European journal of pharmacology vol 589 issue 1-3 2008 18534575 |
continuous administration of isoproterenol for 2 weeks produced heart failure, which is characterized by an increased heart rate, cardiac hypertrophy and downregulation of beta-adrenoceptors. |
2008-10-24 |
2023-01-24 |
rat |
| E Kr\\xc3\\xa1\\xc4\\xbeov\\xc3\\xa1, T Mokr\\xc3\\xa1\\xc5\\x88, J Mur\\xc3\\xadn, T Stankovi\\xc4\\x8dov\\xc3\\xa. Electrocardiography in two models of isoproterenol-induced left ventricular remodeling. Physiological research vol 57 Suppl 2 issue 2008 18373388 |
myocardial hypertrophy in rats was induced by repeated injections of isoproterenol (5 mg/kg s.c. 7 days, iso5, n=7). |
2008-10-16 |
2023-01-24 |
rat |
| Daisuke Takeshita, Juichiro Shimizu, Yutaka Kitagawa, Daisuke Yamashita, Kiyoe Tohne, Chikako Nakajima-Takenaka, Haruo Ito, Miyako Takak. Isoproterenol-induced hypertrophied rat hearts: does short-term treatment correspond to long-term treatment? The journal of physiological sciences : JPS vol 58 issue 3 2008 18462563 |
the aim of the present study was (i) to compare the left ventricular function between rat cardiac hypertrophy models treated with isoproterenol for 3 days (iso 3d) and 7 days (iso 7d) by pressure-volume measurements with a catheter method, and (ii) to follow up the left ventricular function in the same model treated with iso up to 16 weeks with a less-invasive echocardiography. |
2008-10-16 |
2023-01-24 |
rat |