| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guoqiang Wu, Hongxin Wang, Jing Yang, Yuhong Yang, Chunna Liu, Li Jing, Tak Ming Won. kappa-Opioid receptor stimulation inhibits augmentation of Ca(2+) transient and hypertrophy induced by isoprenaline in neonatal rat ventricular myocytes - Role of CaMKIIdelta(B). European journal of pharmacology. vol 595. issue 1-3. 2008-11-18. PMID:18721804. |
we determined the effects of trans-(+/-)-3,4-dichloro-n-methyl-n-[2-(1-pyrrolidinyl)-cyclohexyl]-benzeneacetamid methanesulfonate salt (u50,488h), a selective kappa-opioid receptor agonist, on the enhancement of spontaneous ca(2+) transients and the induction of hypertrophy by isoprenaline, a beta-adrenoceptor agonist, in cultured neonatal ventricular myocytes. |
2008-11-18 |
2023-08-12 |
rat |
| Guoqiang Wu, Hongxin Wang, Jing Yang, Yuhong Yang, Chunna Liu, Li Jing, Tak Ming Won. kappa-Opioid receptor stimulation inhibits augmentation of Ca(2+) transient and hypertrophy induced by isoprenaline in neonatal rat ventricular myocytes - Role of CaMKIIdelta(B). European journal of pharmacology. vol 595. issue 1-3. 2008-11-18. PMID:18721804. |
kappa-opioid receptor stimulation suppressed the stimulatory effect of isoprenaline on ca(2+) transients and cardiac hypertrophy, as did kn93, propranalol and verapamil. |
2008-11-18 |
2023-08-12 |
rat |
| Elham Zarrinpashneh, Christophe Beauloye, Audrey Ginion, Anne-Catherine Pouleur, Xavier Havaux, Louis Hue, Benoit Viollet, Jean-Louis Vanoverschelde, Luc Bertran. AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol. Biochemical and biophysical research communications. vol 376. issue 4. 2008-11-13. PMID:18812163. |
ampkalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol. |
2008-11-13 |
2023-08-12 |
mouse |
| Elham Zarrinpashneh, Christophe Beauloye, Audrey Ginion, Anne-Catherine Pouleur, Xavier Havaux, Louis Hue, Benoit Viollet, Jean-Louis Vanoverschelde, Luc Bertran. AMPKalpha2 counteracts the development of cardiac hypertrophy induced by isoproterenol. Biochemical and biophysical research communications. vol 376. issue 4. 2008-11-13. PMID:18812163. |
we investigated the contribution of ampkalpha2 in the control of cardiac hypertrophy by using ampkalpha2-/- mice submitted to isoproterenol. |
2008-11-13 |
2023-08-12 |
mouse |
| Stevan P Tofovic, Xinchen Zhang, Hong Zhu, Edwin K Jackson, Olga Rafikova, Gordana Petrusevsk. 2-Ethoxyestradiol is antimitogenic and attenuates monocrotaline-induced pulmonary hypertension and vascular remodeling. Vascular pharmacology. vol 48. issue 4-6. 2008-10-27. PMID:18373958. |
the goals of this study were: 1) to compare the effects of e2, 2-me and 2-ee on proliferation of human pulmonary artery endothelial (hpaec) and smooth muscle cells (hpasmc) and lung fibroblasts (hlf); 2) to examine the effects of 2-me, its metabolic precursor 2-hydroxyestradiol (2-he) and 2-ee on isoproterenol (iso)-induced cardiac hypertrophy in male rats; and 3) to investigate in male rats the effects of 2-ee (10 mug/kg/h via osmotic pump) on the development of monocrotaline (mct; 60 mg/kg i.p. |
2008-10-27 |
2023-08-12 |
human |
| Kazuhiko Hanada, Kazuhiko Asari, Masako Saito, Jun-Ichi Kawana, Mitsuo Mita, Hiroyasu Ogat. Comparison of pharmacodynamics between carvedilol and metoprolol in rats with isoproterenol-induced cardiac hypertrophy: effects of carvedilol enantiomers. European journal of pharmacology. vol 589. issue 1-3. 2008-10-24. PMID:18534575. |
continuous administration of isoproterenol for 2 weeks produced heart failure, which is characterized by an increased heart rate, cardiac hypertrophy and downregulation of beta-adrenoceptors. |
2008-10-24 |
2023-08-12 |
rat |
| b' E Kr\\xc3\\xa1\\xc4\\xbeov\\xc3\\xa1, T Mokr\\xc3\\xa1\\xc5\\x88, J Mur\\xc3\\xadn, T Stankovi\\xc4\\x8dov\\xc3\\xa. Electrocardiography in two models of isoproterenol-induced left ventricular remodeling. Physiological research. vol 57 Suppl 2. 2008-10-16. PMID:18373388.' |
myocardial hypertrophy in rats was induced by repeated injections of isoproterenol (5 mg/kg s.c. 7 days, iso5, n=7). |
2008-10-16 |
2023-08-12 |
rat |
| Daisuke Takeshita, Juichiro Shimizu, Yutaka Kitagawa, Daisuke Yamashita, Kiyoe Tohne, Chikako Nakajima-Takenaka, Haruo Ito, Miyako Takak. Isoproterenol-induced hypertrophied rat hearts: does short-term treatment correspond to long-term treatment? The journal of physiological sciences : JPS. vol 58. issue 3. 2008-10-16. PMID:18462563. |
the aim of the present study was (i) to compare the left ventricular function between rat cardiac hypertrophy models treated with isoproterenol for 3 days (iso 3d) and 7 days (iso 7d) by pressure-volume measurements with a catheter method, and (ii) to follow up the left ventricular function in the same model treated with iso up to 16 weeks with a less-invasive echocardiography. |
2008-10-16 |
2023-08-12 |
rat |
| Jian Huang, John M Shelton, James A Richardson, Kristine E Kamm, James T Stul. Myosin regulatory light chain phosphorylation attenuates cardiac hypertrophy. The Journal of biological chemistry. vol 283. issue 28. 2008-08-28. PMID:18474588. |
hearts and cardiomyocytes from wt animals subjected to voluntary running exercise and isoproterenol treatment showed hypertrophic cardiac responses, but the responses for tg mice were attenuated. |
2008-08-28 |
2023-08-12 |
mouse |
| Mario Patrizio, Marco Musumeci, Tonino Stati, Katia Fecchi, Elisabetta Mattei, Liviana Catalano, Giuseppe Maran. Propranolol promotes Egr1 gene expression in cardiomyocytes via beta-adrenoceptors. European journal of pharmacology. vol 587. issue 1-3. 2008-08-25. PMID:18485346. |
remarkably, isoproterenol administration was associated with the development of cardiac hypertrophy, whereas propranolol-treated mice showed a completely normal cardiac morphology. |
2008-08-25 |
2023-08-12 |
mouse |
| Laurent Monassier, Marc-André Laplante, Fabrice Jaffré, Pascal Bousquet, Luc Maroteaux, Jacques de Champlai. Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice. Hypertension (Dallas, Tex. : 1979). vol 52. issue 2. 2008-08-22. PMID:18591460. |
therefore, we measured the effects of serotonergic 5-ht(2b) receptor blockade on left-ventricular superoxide anion generation in 2 established pharmacological models of cardiac hypertrophy, ie, angiotensin ii and isoproterenol infusions in mice. |
2008-08-22 |
2023-08-12 |
mouse |
| Laurent Monassier, Marc-André Laplante, Fabrice Jaffré, Pascal Bousquet, Luc Maroteaux, Jacques de Champlai. Serotonin 5-HT(2B) receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice. Hypertension (Dallas, Tex. : 1979). vol 52. issue 2. 2008-08-22. PMID:18591460. |
similarly, infusion for 5 days of isoproterenol increased left-ventricular nad(p)h oxidase activity (+48%) and cardiac hypertrophy (+31%) that were prevented by the 5-ht(2b) receptor blockade. |
2008-08-22 |
2023-08-12 |
mouse |
| Lick Pui Lai, Jane Mitchel. Beta2-adrenergic receptors expressed on murine chondrocytes stimulate cellular growth and inhibit the expression of Indian hedgehog and collagen type X. Journal of cellular biochemistry. vol 104. issue 2. 2008-07-08. PMID:18059015. |
the cellular expression of two markers of chondrocyte differentiation, indian hedgehog, expressed in pre-hypertrophic cells and collagen type x, expressed in hypertrophic chondrocytes, were both significantly inhibited after incubation with isoproterenol. |
2008-07-08 |
2023-08-12 |
mouse |
| Eduardo Manuel Escudero, Oscar Andrés Pinill. [Paradigms and paradoxes of left ventricular hypertrophy: from the research laboratory to the clinical consultation]. Archivos de cardiologia de Mexico. vol 77. issue 3. 2008-04-29. PMID:18050937. |
after analyzed left ventricular functional and structural changes in rats induced by arterial hypertension, banding of aortic root, isoproterenol administration, or myocardial infarction, as well as in patients with arterial hypertension, aortic stenosis, or hypertrophic miocardiopathy, we found a maladaptive response considered as pathological hypertrophy. |
2008-04-29 |
2023-08-12 |
rat |
| William E Stansfield, Ru-Hang Tang, Nancy C Moss, Albert S Baldwin, Monte S Willis, Craig H Selzma. Proteasome inhibition promotes regression of left ventricular hypertrophy. American journal of physiology. Heart and circulatory physiology. vol 294. issue 2. 2008-03-31. PMID:18032525. |
a murine model of reversible hypertrophy was employed by administering isoproterenol (iso) subcutaneously for 7-14 days. |
2008-03-31 |
2023-08-12 |
Not clear |
| Ahmad Elesber, Rick A Nishimura, Charanjit S Rihal, Steve R Ommen, Hartzell V Schaff, David R Holme. Utility of isoproterenol to provoke outflow tract gradients in patients with hypertrophic cardiomyopathy. The American journal of cardiology. vol 101. issue 4. 2008-03-28. PMID:18312769. |
utility of isoproterenol to provoke outflow tract gradients in patients with hypertrophic cardiomyopathy. |
2008-03-28 |
2023-08-12 |
Not clear |
| Yong-Gang Zhang, Yu-Guang Li, Bao-Guo Liu, Rui-Hong Wei, Dong-Ming Wang, Xue-Rui Tan, Ding-Fang Bu, Yong-Zheng Pang, Chao-Shu Tan. Urotensin II accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol. Acta pharmacologica Sinica. vol 28. issue 1. 2008-03-17. PMID:17184580. |
urotensin ii accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol. |
2008-03-17 |
2023-08-12 |
rat |
| Yong-Gang Zhang, Yu-Guang Li, Bao-Guo Liu, Rui-Hong Wei, Dong-Ming Wang, Xue-Rui Tan, Ding-Fang Bu, Yong-Zheng Pang, Chao-Shu Tan. Urotensin II accelerates cardiac fibrosis and hypertrophy of rats induced by isoproterenol. Acta pharmacologica Sinica. vol 28. issue 1. 2008-03-17. PMID:17184580. |
to study whether urotensin ii (uii), a potent vasoconstrictive peptide, is involved in the development of cardiac hypertrophy and fibrogenesis of rats induced by isoproterenol (iso). |
2008-03-17 |
2023-08-12 |
rat |
| Anderson J Ferreira, Thauana L Oliveira, Maria Carolina M Castro, Alvair P Almeida, Carlos H Castro, Marcelo V Caliari, Elisandra Gava, Gregory T Kitten, Robson A S Santo. Isoproterenol-induced impairment of heart function and remodeling are attenuated by the nonpeptide angiotensin-(1-7) analogue AVE 0991. Life sciences. vol 81. issue 11. 2007-10-26. PMID:17825326. |
heart hypertrophy and heart dysfunction were induced by isoproterenol (iso) (2 mg/kg i.p./day for 7 days) in male wistar rats. |
2007-10-26 |
2023-08-12 |
rat |
| Coskun Ulucan, Xu Wang, Erdene Baljinnyam, Yunzhe Bai, Satoshi Okumura, Motohiko Sato, Susumu Minamisawa, Shinichi Hirotani, Yoshihiro Ishikaw. Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy. American journal of physiology. Heart and circulatory physiology. vol 293. issue 3. 2007-10-19. PMID:17557924. |
in addition to developmental changes, we found that epac gene expression was upregulated in myocardial hypertrophy induced by chronic isoproterenol infusion or pressure overload by transverse aortic banding. |
2007-10-19 |
2023-08-12 |
Not clear |