| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Masanori Ozaki, Seinosuke Kawashima, Tomoya Yamashita, Tetsuaki Hirase, Yoshitaka Ohashi, Nobutaka Inoue, Ken-ichi Hirata, Mitsuhiro Yokoyam. Overexpression of endothelial nitric oxide synthase attenuates cardiac hypertrophy induced by chronic isoproterenol infusion. Circulation journal : official journal of the Japanese Circulation Society. vol 66. issue 9. 2003-06-06. PMID:12224825. |
overexpression of endothelial nitric oxide synthase attenuates cardiac hypertrophy induced by chronic isoproterenol infusion. |
2003-06-06 |
2023-08-12 |
mouse |
| Masanori Ozaki, Seinosuke Kawashima, Tomoya Yamashita, Tetsuaki Hirase, Yoshitaka Ohashi, Nobutaka Inoue, Ken-ichi Hirata, Mitsuhiro Yokoyam. Overexpression of endothelial nitric oxide synthase attenuates cardiac hypertrophy induced by chronic isoproterenol infusion. Circulation journal : official journal of the Japanese Circulation Society. vol 66. issue 9. 2003-06-06. PMID:12224825. |
the present study was designed to determine whether overproduction of endothelial no synthase (enos) could inhibit cardiac hypertrophy induced by chronic isoproterenol (iso) infusion (30mg/kg per day) using enos overexpressing (enos-tg) mice and wild-type (wt) mice. |
2003-06-06 |
2023-08-12 |
mouse |
| Julian C Braz, Orlando F Bueno, Qiangrong Liang, Benjamin J Wilkins, Yan-Shan Dai, Stephanie Parsons, Joseph Braunwart, Betty J Glascock, Raisa Klevitsky, Thomas F Kimball, Timothy E Hewett, Jeffery D Molkenti. Targeted inhibition of p38 MAPK promotes hypertrophic cardiomyopathy through upregulation of calcineurin-NFAT signaling. The Journal of clinical investigation. vol 111. issue 10. 2003-06-04. PMID:12750397. |
moreover, dominant-negative p38alpha, mkk3, and mkk6 transgenic mice each showed enhanced cardiac hypertrophy following aortic banding, ang ii infusion, isoproterenol infusion, or phenylephrine infusion for 14 days. |
2003-06-04 |
2023-08-12 |
mouse |
| Keita Odashiro, Shin-ichi Hiramatsu, Nobuhito Yanagi, Takeshi Arita, Toru Maruyama, Yoshikazu Kaji, Mine Harad. Arrhythmogenic and inotropic effects of interferon investigated in perfused and in vivo rat hearts: influences of cardiac hypertrophy and isoproterenol. Circulation journal : official journal of the Japanese Circulation Society. vol 66. issue 12. 2003-05-08. PMID:12499625. |
arrhythmogenic and inotropic effects of interferon investigated in perfused and in vivo rat hearts: influences of cardiac hypertrophy and isoproterenol. |
2003-05-08 |
2023-08-12 |
human |
| Danelle Badenhorst, Demetri Veliotes, Muzi Maseko, Oupa J Tsotetsi, Richard Brooksbank, Alvin Naidoo, Angela J Woodiwiss, Gavin R Norto. Beta-adrenergic activation initiates chamber dilatation in concentric hypertrophy. Hypertension (Dallas, Tex. : 1979). vol 41. issue 3. 2003-04-11. PMID:12623950. |
we evaluated the effect of 5 months of isoprenaline (0.02 mg x kg(-1) x d(-1)) on hemodynamics, lv wall thickness, cavity size, and interstitial characteristics in spontaneously hypertensive rats (shr) with compensated lv hypertrophy. |
2003-04-11 |
2023-08-12 |
rat |
| Andrzej M Janczewski, Toshiaki Kadokami, Bonnie Lemster, Carole S Frye, Charles F McTiernan, Arthur M Feldma. Morphological and functional changes in cardiac myocytes isolated from mice overexpressing TNF-alpha. American journal of physiology. Heart and circulatory physiology. vol 284. issue 3. 2003-03-11. PMID:12578819. |
tg-f mice showed lv hypertrophy without dilatation and only a small reduction of basal fractional shortening (fs) and response to isoproterenol (iso). |
2003-03-11 |
2023-08-12 |
mouse |
| María Paz Ocaranza, Guillermo Díaz-Araya, Mario Chiong, David Muñoz, Juan Pablo Riveros, Roberto Ebensperger, Sebastián Sabat, Pablo Irarrázaval, Jorge E Jalil, Sergio Lavander. Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis. Journal of cardiovascular pharmacology. vol 40. issue 2. 2002-12-24. PMID:12131554. |
isoproterenol and angiotensin i-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis. |
2002-12-24 |
2023-08-12 |
rat |
| María Paz Ocaranza, Guillermo Díaz-Araya, Mario Chiong, David Muñoz, Juan Pablo Riveros, Roberto Ebensperger, Sebastián Sabat, Pablo Irarrázaval, Jorge E Jalil, Sergio Lavander. Isoproterenol and angiotensin I-converting enzyme in lung, left ventricle, and plasma during myocardial hypertrophy and fibrosis. Journal of cardiovascular pharmacology. vol 40. issue 2. 2002-12-24. PMID:12131554. |
this study investigated whether long-term administration of isoproterenol (iso) induces differential expression of angiotensin-converting enzyme (ace) in lung, plasma, and left ventricle (lv) during development of left ventricular hypertrophy (lvh) and myocardial fibrosis. |
2002-12-24 |
2023-08-12 |
rat |
| Cristina O Silva, Gloria P Duarte, Saad Lahlo. Alpha-adrenergic responsiveness in rat isolated perfused heart after abdominal aortic coarctation. The Journal of pharmacy and pharmacology. vol 54. issue 1. 2002-07-17. PMID:11829125. |
chronic isoproterenol pre-treatment, a well-known model of compensatory hypertrophy associated with cardiac beta-adrenoceptor desensitization, enhances the inotropic response to phenylephrine in rat isolated perfused hearts, supporting the hypothesis that myocardial alpha-adrenoceptor stimulation contributes to the maintenance of myocardial performance in situations in which cardiac beta-adrenoceptor function is compromised. |
2002-07-17 |
2023-08-12 |
rat |
| Kelly G Ten Hagen, Marlene M Balys, Lawrence A Tabak, James E Melvi. Analysis of isoproterenol-induced changes in parotid gland gene expression. Physiological genomics. vol 8. issue 2. 2002-05-06. PMID:11875188. |
parotid gland acinar cells undergo marked hypertrophy and hyperplasia upon systemic exposure to the beta-adrenergic agonist, isoproterenol. |
2002-05-06 |
2023-08-12 |
mouse |
| Orlando F Bueno, Benjamin J Wilkins, Kevin M Tymitz, Betty J Glascock, Thomas F Kimball, John N Lorenz, Jeffery D Molkenti. Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice. Proceedings of the National Academy of Sciences of the United States of America. vol 99. issue 7. 2002-04-25. PMID:11904392. |
cnabeta-deficient mice were dramatically impaired in their ability to mount a productive hypertrophic response induced by pressure overload, angiotensin ii infusion, or isoproterenol infusion. |
2002-04-25 |
2023-08-12 |
mouse |
| Birgit Andrée, Anne Fleige, Hans-Henning Arnold, Thomas Bran. Mouse Pop1 is required for muscle regeneration in adult skeletal muscle. Molecular and cellular biology. vol 22. issue 5. 2002-04-02. PMID:11839816. |
no difference, however, was observed between homozygous and heterozygous mice in the ability to develop cardiac hypertrophy in response to isoproterenol. |
2002-04-02 |
2023-08-12 |
mouse |
| W Wallis, M Cooklin, D J Sheridan, C H Fr. The action of isoprenaline on the electrophysiological properties of hypertrophied left ventricular myocytes. Archives of physiology and biochemistry. vol 109. issue 2. 2002-03-07. PMID:11780772. |
the augmentation of i(ca) and i(cl) by isoprenaline was also reduced in hypertrophy, but no other characteristics of the two currents, or the dose-dependency of the action of isoprenaline were a function of cardiac growth. |
2002-03-07 |
2023-08-12 |
Not clear |
| N Balta, I Stoian, C Petec, G Pete. Decreased SOD activity and increased nitrates level in rat heart with left ventricular hypertrophy induced by isoproterenol. Romanian journal of physiology : physiological sciences. vol 36. issue 3-4. 2002-01-31. PMID:11797933. |
decreased sod activity and increased nitrates level in rat heart with left ventricular hypertrophy induced by isoproterenol. |
2002-01-31 |
2023-08-12 |
rat |
| N Balta, I Stoian, C Petec, G Pete. Decreased SOD activity and increased nitrates level in rat heart with left ventricular hypertrophy induced by isoproterenol. Romanian journal of physiology : physiological sciences. vol 36. issue 3-4. 2002-01-31. PMID:11797933. |
in an attempt to understand the molecular basis of antioxidant changes during ventricular hypertrophy, we have used isoproterenol treated rats. |
2002-01-31 |
2023-08-12 |
rat |
| F H Leenen, R White, B Yua. Isoproterenol-induced cardiac hypertrophy: role of circulatory versus cardiac renin-angiotensin system. American journal of physiology. Heart and circulatory physiology. vol 281. issue 6. 2002-01-07. PMID:11709406. |
to assess the possible contribution of the circulatory and cardiac renin-angiotensin system (ras) to the cardiac hypertrophy induced by a beta-agonist, the present study evaluated the effects of isoproterenol, alone or combined with an angiotensin i-converting enzyme inhibitor or at(1) receptor blocker, on plasma and lv renin activity, ang i, and ang ii, as well as left ventricular (lv) and right ventricular (rv) weight. |
2002-01-07 |
2023-08-12 |
rat |
| L M Shantz, D J Feith, A E Peg. Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy. The Biochemical journal. vol 358. issue Pt 1. 2001-09-20. PMID:11485548. |
however, stimulation of beta-adrenergic signalling by isoproterenol resulted in severe hypertrophy and even death in odc-overexpressing mice without further altering polyamine levels, compared with only a mild hypertrophy in littermates. |
2001-09-20 |
2023-08-12 |
mouse |
| L M Shantz, D J Feith, A E Peg. Targeted overexpression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy. The Biochemical journal. vol 358. issue Pt 1. 2001-09-20. PMID:11485548. |
when beta1-adrenergic stimulation was blocked by simultaneous treatment with isoproterenol and the beta1 antagonist atenolol, a significant, although reduced, hypertrophy was still present in the hearts of transgenic mice, suggesting that both beta1 and beta2 adrenergic receptors contribute to the hypertrophic phenotype. |
2001-09-20 |
2023-08-12 |
mouse |
| N Murad, M Fabiano de Franco, P J Tucc. [Functional characterization of myocardial hypertrophy induced by isoproterenol and its regression]. Arquivos brasileiros de cardiologia. vol 77. issue 1. 2001-09-13. PMID:11500747. |
[functional characterization of myocardial hypertrophy induced by isoproterenol and its regression]. |
2001-09-13 |
2023-08-12 |
Not clear |
| J Mészáros, D Khananshvili, G Har. Mechanisms underlying delayed afterdepolarizations in hypertrophied left ventricular myocytes of rats. American journal of physiology. Heart and circulatory physiology. vol 281. issue 2. 2001-08-16. PMID:11454597. |
cardiac hypertrophy was induced in rats by daily injection of isoproterenol (5 mg/kg ip) for 7 days. |
2001-08-16 |
2023-08-12 |
rat |