| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Abu Mohammad Syed, Sourav Kundu, Chetan Ram, Uttam Kulhari, Akhilesh Kumar, Madhav Nilakanth Mugale, Upadhyayula Suryanarayana Murty, Bidya Dhar Sah. Aloin alleviates pathological cardiac hypertrophy via modulation of the oxidative and fibrotic response. Life sciences vol 288 issue 2021 34801516 |
this study investigated the effect of aloin against the isoproterenol (iso)-induced cardiac hypertrophy in rats. |
2021-12-11 |
2023-01-26 |
rat |
| Mi-Hyeon Hong, Se-Won Na, Youn-Jae Jang, Jung-Joo Yoon, Yun-Jung Lee, Ho-Sub Lee, Hye-Yoom Kim, Dae-Gill Kan. Betulinic Acid Improves Cardiac-Renal Dysfunction Caused by Hypertrophy through Calcineurin-NFATc3 Signaling. Nutrients vol 13 issue 10 2021 34684485 |
however, as the potential effect of ba on cardiac hypertrophy and consequent renal dysfunction is unknown, we investigated the effect of ba on isoprenaline (iso)-induced cardiac hypertrophy and related signaling. |
2021-11-18 |
2023-01-26 |
Not clear |
| Xue-Cui Wu, Cheng-Fu Yuan, Yu-Min He, Zhi-Yong Zhou, Yue Luo, Meng-Ting Yang, Xiao-Xiao Li, Chao-Qi Li. [Chikusetsu saponin \\xe2\\x85\\xa3a ameliorates myocardial hypertrophy of rats through regulating expression of miR199a-5p/Atg5]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica vol 46 issue 19 2021 34738402 |
the present study investigated the effects of chikusetsu saponin \xe2\x85\xa3a(chs \xe2\x85\xa3a) on isoproterenol(iso)-induced myocardial hypertrophy in rats and explored the underlying molecular mechanism. |
2021-11-08 |
2023-01-26 |
rat |
| Kuniya Asai, Koji Murai, Akihiro Shirakabe, Masataka Kamiya, Satsuki Noma, Naoki Sato, Kyoichi Mizuno, Wataru Shimiz. Effect of Gonadectomy and Angiotensin II Receptor Blockade in a Mouse Model of Isoproterenol-induced Cardiac Diastolic Dysfunction. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi vol 88 issue 2 2021 32475904 |
we examined the effect of gonadectomy with or without the angiotensin receptor blocker olmesartan (olm) in an isoproterenol (iso) -induced mouse model of left ventricular hypertrophy (lvh) and cardiac diastolic dysfunction. |
2021-10-26 |
2023-01-26 |
Not clear |
| Lingmin Mu, Changqin Jing, Zhikun Gu. Expression of N-cadherin proteins in myocardial hypertrophy in rats. Experimental and therapeutic medicine vol 7 issue 2 2021 24396404 |
a myocardial hypertrophy model was established by subcutaneously injecting isoprenaline into healthy adult sprague-dawley rats. |
2021-10-21 |
2023-01-25 |
rat |
| Stacey L House, Brian E House, Betty Glascock, Thomas Kimball, Eyad Nusayr, Jo El J Schultz, Thomas Doetschma. Fibroblast Growth Factor 2 Mediates Isoproterenol-induced Cardiac Hypertrophy through Activation of the Extracellular Regulated Kinase. Molecular and cellular pharmacology vol 2 issue 4 2021 21274419 |
to ascertain the role of fgf2 in cardiac hypertrophy, wildtype, fgf2 knockout, non-transgenic, and fgf2 transgenic mice were treated with isoproterenol or saline via subcutaneous mini-osmotic pump implants to induce a hypertrophic response to \xce\xb2-adrenergic stimulation. |
2021-10-20 |
2023-01-25 |
mouse |
| Stacey L House, Brian E House, Betty Glascock, Thomas Kimball, Eyad Nusayr, Jo El J Schultz, Thomas Doetschma. Fibroblast Growth Factor 2 Mediates Isoproterenol-induced Cardiac Hypertrophy through Activation of the Extracellular Regulated Kinase. Molecular and cellular pharmacology vol 2 issue 4 2021 21274419 |
echocardiography reveals significantly decreased fractional shortening in isoproterenol-treated fgf2 transgenic mice but not in fgf2 knockout mice suggesting that fgf2 mediates the maladaptive cardiac dysfunction seen in cardiac hypertrophy induced by isoproterenol. |
2021-10-20 |
2023-01-25 |
mouse |
| Yonglin Zhang, Zhenglu Shang, Aijun Li. Angiotensin-(3-7) alleviates isoprenaline-induced cardiac remodeling via attenuating cAMP-PKA and PI3K/Akt signaling pathways. Amino acids vol 53 issue 10 2021 34494132 |
the administration of ang-(3-7) alleviated isoprenaline (iso)-induced cardiac hypertrophy and fibrosis of mice. |
2021-10-19 |
2023-01-26 |
rat |
| Yuan Li, Wei-Wei Zhou, Jia-Huan Sun, Hong-Xia Yang, Geng-Rui Xu, Yue Zhang, Qiu-Hang Song, Chuang Zhang, Wei-Zhe Liu, Xing-Chao Liu, Ai-Ying L. Modified citrus pectin prevents isoproterenol-induced cardiac hypertrophy associated with p38 signalling and TLR4/JAK/STAT3 pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie vol 143 issue 2021 34649308 |
the aim of this study is to investigate the role and mechanism of mcp in isoproterenol (iso)-induced cardiac hypertrophy. |
2021-10-15 |
2023-01-26 |
rat |
| Jing Lu, Suowen Xu, Yuqing Huo, Duanping Sun, Yuehuai Hu, Junjian Wang, Xiaolei Zhang, Panxia Wang, Zhuoming Li, Mengya Liang, Zhongkai Wu, Peiqing Li. Sorting nexin 3 induces heart failure via promoting retromer-dependent nuclear trafficking of STAT3. Cell death and differentiation vol 28 issue 10 2021 33947971 |
we report that snx3-cko in mice significantly protected against isoproterenol (iso)-induced cardiac hypertrophy at 12 weeks. |
2021-10-09 |
2023-01-26 |
mouse |
| Bing-Yan Liu, Ling Li, Gao-Li Liu, Wei Ding, Wen-Guang Chang, Tao Xu, Xiao-Yu Ji, Xian-Xin Zheng, Jing Zhang, Jian-Xun Wan. Baicalein attenuates cardiac hypertrophy in mice via suppressing oxidative stress and activating autophagy in cardiomyocytes. Acta pharmacologica Sinica vol 42 issue 5 2021 32796955 |
cardiac hypertrophy was induced in mice by injection of isoproterenol (iso, 30\xe2\x80\x89mg\xc2\xb7kg |
2021-09-27 |
2023-01-26 |
mouse |
| Naijin Zhang, Ying Zhang, Hao Qian, Shaojun Wu, Liu Cao, Yingxian Su. Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling. Cell death and differentiation vol 27 issue 9 2021 32139900 |
we determined that the knockout of wwp2 specifically in myocardium decreased the level of parp1 ubiquitination and increased the effects of isoproterenol (iso)-induced parp1 and parylation, in turn aggravating iso-induced myocardial hypertrophy, heart failure, and myocardial fibrosis. |
2021-09-23 |
2023-01-26 |
Not clear |
| Weinian Gao, Na Guo, Shuguang Zhao, Ziying Chen, Wenli Zhang, Fang Yan, Hongjuan Liao, Kui Ch. HTR2A promotes the development of cardiac hypertrophy by activating PI3K-PDK1-AKT-mTOR signaling. Cell stress & chaperones vol 25 issue 6 2021 32519137 |
besides, the expression of htr2a was also upregulated in isoproterenol (iso)-induced cardiac hypertrophy in the mouse. |
2021-09-21 |
2023-01-26 |
rat |
| Mi Tian, Xiuxin Jiang, Xinyun Li, Jianmin Yang, Cheng Zhang, Wencheng Zhan. LKB1IP promotes pathological cardiac hypertrophy by targeting PTEN/Akt signalling pathway. Journal of cellular and molecular medicine vol 25 issue 5 2021 33486894 |
we investigated the cardiac level of lkb1ip in samples from patients with heart failure and mice with cardiac hypertrophy induced by isoproterenol (iso) or transverse aortic constriction (tac). |
2021-09-21 |
2023-01-26 |
mouse |
| Yao Xu, Chen Liang, Ying Luo, Tongcun Zhan. MBNL1 regulates isoproterenol-induced myocardial remodelling in vitro and in vivo. Journal of cellular and molecular medicine vol 25 issue 2 2021 33295096 |
in this study, we observed the high expression of mbnl1 in cardiac tissue and peripheral blood of an isoproterenol (iso)-induced cardiac hypertrophy mouse model. |
2021-09-14 |
2023-01-26 |
human |
| Nanqi Cui, Takayuki Sakurai, Akiko Kamiyoshi, Yuka Ichikawa-Shindo, Hisaka Kawate, Megumu Tanaka, Masaaki Tanaka, Yangxuan Wei, Shinji Kakihara, Yunlu Zhao, Kohsuke Aruga, Hiroyuki Kawagishi, Tsutomu Nakada, Mitsuhiko Yamada, Takayuki Shind. Adrenomedullin-RAMP2 and -RAMP3 Systems Regulate Cardiac Homeostasis during Cardiovascular Stress. Endocrinology vol 162 issue 3 2021 33545715 |
exposing c-ramp2-/- cardiomyocytes to isoproterenol enhanced their hypertrophy and oxidative stress compared with wild-type cells. |
2021-09-10 |
2023-01-26 |
mouse |
| S Hern\\xc3\\xa1ndez-Guti\\xc3\\xa9rrez, J Roque-Jorge, A L\\xc3\\xb3pez-Torres, G D\\xc3\\xadaz-Rosas, A J Garc\\xc3\\xada-Chequer, A Contreras-Ramo. Role of sodium tetraborate as a cardioprotective or competitive agent: Modulation of hypertrophic intracellular signals. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) vol 62 issue 2021 32563862 |
however, sodium tetraborate attenuates isoproterenol induced hypertrophy damage in cardiomyocytes when these two compounds are added simultaneously. |
2021-08-19 |
2023-01-26 |
Not clear |
| Dharaniyambigai Kuberapandian, Victor Arokia Dos. Identification of serum predictors of n-acetyl-l-cysteine and isoproterenol induced remodelling in cardiac hypertrophy. Turkish journal of biology = Turk biyoloji dergisi vol 45 issue 3 2021 34377056 |
identification of serum predictors of n-acetyl-l-cysteine and isoproterenol induced remodelling in cardiac hypertrophy. |
2021-08-12 |
2023-01-26 |
Not clear |
| Jiantao Qiu, Huaiteng Xiao, Shunchang Zhou, Weimin Du, Xiang Mu, Guangjun Shi, Xueying Ta. Bone marrow mesenchymal stem cells inhibit cardiac hypertrophy by enhancing FoxO1 transcription. Cell biology international vol 45 issue 1 2021 33049085 |
we induced cardiomyocyte hypertrophy in cultured rat cells through isoproterenol (iso) treatment with or without bmsc coculture. |
2021-08-11 |
2023-01-26 |
rat |
| Hongfei Xu, Zhen Wang, Miao Chen, Wenting Zhao, Tingting Tao, Liang Ma, Yiming Ni, Weidong L. YTHDF2 alleviates cardiac hypertrophy via regulating Myh7 mRNA decoy. Cell & bioscience vol 11 issue 1 2021 34266473 |
primary cardiomyocytes were isolated and stimulated with isoproterenol (iso) or phenylephrine (phe) to induce myocardial hypertrophy. |
2021-07-18 |
2023-01-26 |
human |