| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yong Li, Xuguan Chen, Peng Li, Qianxuan Xiao, Daorong Hou, Xiangqing Kon. CD47 antibody suppresses isoproterenol-induced cardiac hypertrophy through activation of autophagy. American journal of translational research. vol 12. issue 9. 2020-10-13. PMID:33042468. |
in this study, we investigated whether cd47 antibody could attenuate isoproterenol (iso)-induced cardiac hypertrophy in mice and h9c2 cells. |
2020-10-13 |
2023-08-13 |
mouse |
| Xin-Qiu-Yue Wang, Zong-Tang Xu, Gui-Ping Zhang, Ning Hou, Qin-Xing Mo, Jie Wei, Xin Jiang, Yun Liu, Jian-Dong Lu. Endophilin A2 attenuates cardiac hypertrophy induced by isoproterenol through the activation of autophagy. American journal of translational research. vol 11. issue 8. 2020-10-01. PMID:31497222. |
endophilin a2 attenuates cardiac hypertrophy induced by isoproterenol through the activation of autophagy. |
2020-10-01 |
2023-08-13 |
Not clear |
| Tarak N Khatua, Roshan M Borkar, Soheb A Mohammed, Amit K Dinda, R Srinivas, Sanjay K Banerje. Novel Sulfur Metabolites of Garlic Attenuate Cardiac Hypertrophy and Remodeling through Induction of Na Frontiers in pharmacology. vol 8. 2020-09-30. PMID:28194108. |
therefore, the objective of the present study was to (1) investigate the effect of raw garlic on isoproterenol (iso) induced cardiac hypertrophy (2) find the active metabolites of garlic responsible for the beneficial effect. |
2020-09-30 |
2023-08-13 |
rat |
| Tarak Nath Khatua, Amit K Dinda, Uday K Putcha, Sanjay K Banerje. Diallyl disulfide ameliorates isoproterenol induced cardiac hypertrophy activating mitochondrial biogenesis via eNOS-Nrf2-Tfam pathway in rats. Biochemistry and biophysics reports. vol 5. 2020-09-30. PMID:28955809. |
diallyl disulfide ameliorates isoproterenol induced cardiac hypertrophy activating mitochondrial biogenesis via enos-nrf2-tfam pathway in rats. |
2020-09-30 |
2023-08-13 |
rat |
| Glenmore Lasa. Brockenbrough-Braunwald-Morrow Sign: An Evaluative Hemodynamic Maneuver for Left Ventricular Outflow Tract Obstruction. Cardiology research. vol 9. issue 3. 2020-09-30. PMID:29904456. |
her coronary angiogram revealed normal coronary arteries but with hypertrophic obstructive cardiomyopathy with an increasing left ventricular-aortic gradient on isoproterenol provocation. |
2020-09-30 |
2023-08-13 |
Not clear |
| Weichun Qian, Dongsheng Yu, Jia Zhang, Qiaoyun Hu, Chuanfeng Tang, Peiyu Liu, Peng Ye, Xiaoli Wang, Qiu Lv, Minglong Chen, Liang Shen. Wogonin Attenuates Isoprenaline-Induced Myocardial Hypertrophy in Mice by Suppressing the PI3K/Akt Pathway. Frontiers in pharmacology. vol 9. 2020-09-29. PMID:30150938. |
myocardial hypertrophy was replicated by the subcutaneous implantation of an isoprenaline mini-pump in mice or isoprenaline treatment of h9c2 cells. |
2020-09-29 |
2023-08-13 |
mouse |
| Nasiruddin Nalban, Rajendra Sangaraju, Sateesh Alavala, Salma Mukhtar Mir, Mahesh Kumar Jerald, Ramakrishna Sistl. Arbutin Attenuates Isoproterenol-Induced Cardiac Hypertrophy by Inhibiting TLR-4/NF-κB Pathway in Mice. Cardiovascular toxicology. vol 20. issue 3. 2020-09-28. PMID:31485892. |
the study aims to understand the effect of arbutin on isoproterenol (iso)-induced cardiac hypertrophy in mice. |
2020-09-28 |
2023-08-13 |
mouse |
| Marianne K O Grant, Ibrahim Y Abdelgawad, Christine A Lewis, Davis Seelig, Beshay N Zordok. Lack of sexual dimorphism in a mouse model of isoproterenol-induced cardiac dysfunction. PloS one. vol 15. issue 7. 2020-09-10. PMID:32645007. |
similarly, prolonged isoproterenol administration induced hypertrophic and fibrotic genes in hearts of male and female mice to the same extent. |
2020-09-10 |
2023-08-13 |
mouse |
| S-S Song, G Tang, L-X Tang, L-Y Si, W Xion. NAKα2 inhibits fibrosis formation and protects against cardiomyocyte hypertrophy by suppressing hypertrophy associated molecules and activating LTCC/NCX signaling pathway. European review for medical and pharmacological sciences. vol 23. issue 7. 2020-09-08. PMID:31002153. |
this study aimed to evaluate effects of na+/k+ aptaseα2 (nakα2) on isoprenaline (iso) induced cardiomyocyte hypertrophy. |
2020-09-08 |
2023-08-13 |
Not clear |
| Lihua Qi, Xiaochun Chi, Xi Zhang, Xueqian Feng, Wenhui Chu, Shengchang Zhang, Junzhou Wu, Yao Song, Youyi Zhang, Wei Kong, Yu Yu, Hongquan Zhan. Kindlin-2 suppresses transcription factor GATA4 through interaction with SUV39H1 to attenuate hypertrophy. Cell death & disease. vol 10. issue 12. 2020-08-31. PMID:31767831. |
we found that kindlin-2 suppresses the expression of gata4 through binding to its promoter and prevents cardiomyocytes from hypertrophy induced by isoproterenol (iso) treatment. |
2020-08-31 |
2023-08-13 |
mouse |
| Toru Miyoshi, Kazufumi Nakamura, Daiji Miura, Masashi Yoshida, Yukihiro Saito, Satoshi Akagi, Yuko Ohno, Megumi Kondo, Hiroshi It. Effect of LCZ696, a dual angiotensin receptor neprilysin inhibitor, on isoproterenol-induced cardiac hypertrophy, fibrosis, and hemodynamic change in rats. Cardiology journal. vol 26. issue 5. 2020-07-28. PMID:29718530. |
this study evaluated whether lcz696 affects left ventricular hypertrophy, fibrosis, and hemodynamics in isoproterenol (iso)-treated rats compared with valsartan alone. |
2020-07-28 |
2023-08-13 |
rat |
| Yaoxu Chen, Huimin Beng, Hao Su, Fuping Han, Zhuo Fan, Nanying Lv, Aleksandar Jovanović, Wen Ta. Isosteviol prevents the development of isoprenaline‑induced myocardial hypertrophy. International journal of molecular medicine. vol 44. issue 5. 2020-07-27. PMID:31545484. |
in the current study, whether stvna interferes with the development of cardiac hypertrophy, which is induced by isoprenaline (iso), was investigated in an experimental rat model. |
2020-07-27 |
2023-08-13 |
rat |
| Si Zhang, Zhongnan Yin, Fei-Fei Dai, Hao Wang, Meng-Jiao Zhou, Ming-Hui Yang, Shu-Feng Zhang, Zhi-Feng Fu, Ying-Wu Mei, Ming-Xi Zang, Lixiang Xu. miR-29a attenuates cardiac hypertrophy through inhibition of PPARδ expression. Journal of cellular physiology. vol 234. issue 8. 2020-05-08. PMID:30580435. |
in addition, we identify a novel role of mir-29a, in which it has a cardioprotective function in isoproterenol hydrochloride-induced cardiac hypertrophy by targeting pparδ and downregulating anf. |
2020-05-08 |
2023-08-13 |
Not clear |
| Si Zhang, Zhongnan Yin, Fei-Fei Dai, Hao Wang, Meng-Jiao Zhou, Ming-Hui Yang, Shu-Feng Zhang, Zhi-Feng Fu, Ying-Wu Mei, Ming-Xi Zang, Lixiang Xu. miR-29a attenuates cardiac hypertrophy through inhibition of PPARδ expression. Journal of cellular physiology. vol 234. issue 8. 2020-05-08. PMID:30580435. |
finally, we provide evidence that mir-29a reduces the isoproterenol hydrochloride-induced cardiac hypertrophy response, thereby underlining the potential clinical relevance of mir-29a in which it may serve as a potent therapeutic target for heart hypertrophy treatment. |
2020-05-08 |
2023-08-13 |
Not clear |
| Isil Ozakc. Antihypertrophic Effects of Nebivolol on Neonatal Cardiomyocyte Hypertrophy Models. Journal of cardiovascular pharmacology. vol 73. issue 3. 2020-05-04. PMID:30601193. |
in the current study, in vitro cardiomyocyte hypertrophy model was induced with isoprenaline (10 μm), angiotensin ii (1 μm), and phenylephrine (20 μm) in neonatal cardiomyocytes isolated from 0- to 2-day-old sprague-dawley rats. |
2020-05-04 |
2023-08-13 |
rat |
| Zhengbo Zhao, Han Liu, Dongmei Gu. Aliskiren attenuates cardiac dysfunction by modulation of the mTOR and apoptosis pathways. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 2. 2020-04-07. PMID:31994601. |
a rat model of cardiac hypertrophy was induced by isoproterenol treatment (5 mg·kg-1·day-1) for 4 weeks, with or without als treatment at 20 mg·kg-1·day-1. |
2020-04-07 |
2023-08-13 |
rat |
| Kai-Chun Cheng, Yingxiao Li, Wei-Ting Chang, Zhih-Cherng Chen, Juei-Tang Cheng, Cheng-Chia Tsa. Ubiquitin-protein ligase E3a (UBE3A) as a new biomarker of cardiac hypertrophy in cell models. Journal of food and drug analysis. vol 27. issue 1. 2020-03-23. PMID:30648591. |
the cardiac hypertrophy is induced in rat-derived heart cell line h9c2 cells by potassium bromate (kbro3), high glucose (hg), or isoproterenol (iso), respectively. |
2020-03-23 |
2023-08-13 |
Not clear |
| Stephanie Binas, Maria Knyrim, Julia Hupfeld, Udo Kloeckner, Sindy Rabe, Sigrid Mildenberger, Katja Quarch, Nicole Strätz, Danny Misiak, Michael Gekle, Claudia Grossmann, Barbara Schreie. miR-221 and -222 target CACNA1C and KCNJ5 leading to altered cardiac ion channel expression and current density. Cellular and molecular life sciences : CMLS. vol 77. issue 5. 2020-03-18. PMID:31312877. |
additionally, we evaluated the change of mir-221/222 in vivo in two models of pharmacologically induced heart hypertrophy (angiotensin ii, isoprenaline), thereby demonstrating a stimulus-induced increase in mir-221/222 in vivo by angiotensin ii but not by isoprenaline. |
2020-03-18 |
2023-08-13 |
mouse |
| Yanfei Li, Linlin Ma, Sijie Gu, Jiewen Tian, Yilin Cao, Zi Jin, Jingyi Chen, Bingbing Gu, Jiayin Tu, Zhixiao Wang, Xinming Li, Zhongping Ning, Yueling Ji. UBE3A alleviates isoproterenol-induced cardiac hypertrophy through the inhibition of the TLR4/MMP-9 signaling pathway. Acta biochimica et biophysica Sinica. vol 52. issue 1. 2020-02-26. PMID:31681945. |
in this study, we explored the potential mechanism underlying cardiac hypertrophy induced by isoproterenol. |
2020-02-26 |
2023-08-13 |
Not clear |
| Yanfei Li, Linlin Ma, Sijie Gu, Jiewen Tian, Yilin Cao, Zi Jin, Jingyi Chen, Bingbing Gu, Jiayin Tu, Zhixiao Wang, Xinming Li, Zhongping Ning, Yueling Ji. UBE3A alleviates isoproterenol-induced cardiac hypertrophy through the inhibition of the TLR4/MMP-9 signaling pathway. Acta biochimica et biophysica Sinica. vol 52. issue 1. 2020-02-26. PMID:31681945. |
our results showed that isoproterenol induced cardiac hypertrophy in ac16 cells, as reflected by the increased cell surface area and increased hypertrophic markers, which was accompanied by increased ubiquitin-protein ligase e3a (ube3a) expression. |
2020-02-26 |
2023-08-13 |
Not clear |