| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuhua Fan, Li Liu, Kun Fang, Tao Huang, Lin Wan, Youbin Liu, Sen Zhang, Dongxia Yan, Guangnan Li, Yanhui Gao, Yanjie Lv, Yanjun Chen, Yingfeng T. Resveratrol Ameliorates Cardiac Hypertrophy by Down-regulation of miR-155 Through Activation of Breast Cancer Type 1 Susceptibility Protein. Journal of the American Heart Association vol 5 issue 4 2017 27107135 |
the polyphenol resveratrol (rev) has been reported to exhibit cardioprotective effects, such as inhibition of tac (transverse aortic constriction) or isoprenaline (iso)-induced hypertrophy. |
2017-11-02 |
2023-01-25 |
Not clear |
| Rongrong Sun, Baoling Zhu, Kai Xiong, Yan Sun, Dandan Shi, Li Chen, Youyi Zhang, Zijian Li, Lixiang Xu. Senescence as a novel mechanism involved in \\xce\\xb2-adrenergic receptor mediated cardiac hypertrophy. PloS one vol 12 issue 8 2017 28783759 |
to verify this hypothesis and examine whether cardiac senescence is a novel mechanism of hypertrophy induced by isoproterenol, 2-month-old male sprague dawley rats were subjected to isoproterenol infusion (0.25mg/kg/day) for 7 days by subcutaneous injection). |
2017-10-06 |
2023-01-26 |
rat |
| Rongrong Sun, Baoling Zhu, Kai Xiong, Yan Sun, Dandan Shi, Li Chen, Youyi Zhang, Zijian Li, Lixiang Xu. Senescence as a novel mechanism involved in \\xce\\xb2-adrenergic receptor mediated cardiac hypertrophy. PloS one vol 12 issue 8 2017 28783759 |
our results showed for the first time that cardiac senescence is involved in the process of pathological cardiac hypertrophy induced by isoproterenol. |
2017-10-06 |
2023-01-26 |
rat |
| Ying Feng, Jun Cheng, Baozhu Wei, Yanggan Wan. CaMKII inhibition reduces isoproterenol-induced ischemia and arrhythmias in hypertrophic mice. Oncotarget vol 8 issue 11 2017 28177919 |
here, we investigated the effect of camkii inhibition in isoproterenol (iso)-induced arrhythmias in hypertrophic mice. |
2017-09-20 |
2023-01-26 |
mouse |
| W Xu, Y Wang, J Zhou, X Zhu, S Zhang, W Yuan, X Liu, Y Shi, L Cao, Q Zeng, Z Jiang, X Ye, Y Wan, X Peng, Y Deng, F Chen, X Wang, G Dai, S Luo, X Fan, X Mo, X Wu, Y L. Cardiac Specific Overexpression of hHole Attenuates Isoproterenol-Induced Hypertrophic Remodeling through Inhibition of Extracellular Signal-Regulated Kinases (ERKs) Signalling. Current molecular medicine vol 16 issue 5 2017 27211802 |
in a cardiac specific transgenic mouse model, it was observed that overexpression of hhole specifically in heart attenuated cardiac hypertrophy and fibrosis induced by isoproterenol (iso), with blunted transcriptions of erk1/2, total erk1/2 proteins and phosphorylated erk1/2 (p-erk1/2) levels. |
2017-09-15 |
2023-01-25 |
mouse |
| Anne J\\xc3\\xa4rve, Silke M\\xc3\\xbchlstedt, Fatimunnisa Qadri, Bernadette Nickl, Herbert Schulz, Norbert H\\xc3\\xbcbner, Cemil \\xc3\\x96zcelik, Michael Bade. Adverse left ventricular remodeling by glycoprotein nonmetastatic melanoma protein B in myocardial infarction. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol 31 issue 2 2017 28148779 |
moreover, gpnmb deficiency attenuated the dilated cardiomyopathy in muscle lim protein knockout mice but could not prevent cardiac hypertrophy induced by isoprenaline infusion. |
2017-09-01 |
2023-01-26 |
rat |
| Jie Lou, Dan Zhao, Ling-Ling Zhang, Shu-Ying Song, Yan-Chao Li, Fei Sun, Xiao-Qing Ding, Chang-Jiang Yu, Yuan-Yuan Li, Mei-Tong Liu, Chang-Jiang Dong, Yong Ji, Hongliang Li, Wenfeng Chu, Zhi-Ren Zhan. Type III Transforming Growth Factor-\\xce\\xb2 Receptor Drives Cardiac Hypertrophy Through \\xce\\xb2-Arrestin2-Dependent Activation of Calmodulin-Dependent Protein Kinase II. Hypertension (Dallas, Tex. : 1979) vol 68 issue 3 2017 27432858 |
cardiac-specific transgenic expression of t\xce\xb2riii independently led to cardiac hypertrophy in mice, which was further aggravated by isoproterenol and tac treatment. |
2017-08-07 |
2023-01-25 |
mouse |
| Jamaira A Victorio, Stefano P Clerici, Roberto Palacios, Mar\\xc3\\xada J Alonso, Dalton V Vassallo, Iris Z Jaffe, Luciana V Rossoni, Ana P Dave. Spironolactone Prevents Endothelial Nitric Oxide Synthase Uncoupling and Vascular Dysfunction Induced by \\xce\\xb2-Adrenergic Overstimulation: Role of Perivascular Adipose Tissue. Hypertension (Dallas, Tex. : 1979) vol 68 issue 3 2017 27432866 |
\xce\xb2-ar overstimulation with associated cardiac hypertrophy and increased vasoconstrictor response to phenylephrine in aorta were modeled in rats by 7-day isoproterenol treatment. |
2017-08-07 |
2023-01-25 |
rat |
| Lung-Shuo Wang, Chun-Ting Lee, Wei-Lieh Su, Shih-Che Huang, Shu-Chi Wan. Delonix regia Leaf Extract (DRLE): A Potential Therapeutic Agent for Cardioprotection. PloS one vol 11 issue 12 2017 27936072 |
in this study, we found that the delonix regia leaf extract (drle) (400 mg/kg/d) can reduce the mortality rate in an isoproterenol (iso)-induced heart injury and hypertrophy mouse model. |
2017-07-10 |
2023-01-26 |
mouse |
| Jing Lu, Duanping Sun, Zhiping Liu, Min Li, Huiqi Hong, Cui Liu, Si Gao, Hong Li, Yi Cai, Shaorui Chen, Zhuoming Li, Jiantao Ye, Peiqing Li. SIRT6 suppresses isoproterenol-induced cardiac hypertrophy through activation of autophagy. Translational research : the journal of laboratory and clinical medicine vol 172 issue 2017 27016702 |
primary neonatal rat cardiomyocytes (nrcms) or sprague-dawley (sd) rats were submitted to isoproterenol (iso) treatment, and then the hypertrophic responses and changes in autophagy activity were measured. |
2017-06-26 |
2023-01-25 |
rat |
| Quanlu Duan, Li Ni, Peihua Wang, Chen Chen, Lei Yang, Ben Ma, Wei Gong, Zhejun Cai, Ming-Hui Zou, Dao Wen Wan. Deregulation of XBP1 expression contributes to myocardial vascular endothelial growth factor-A expression and angiogenesis during cardiac hypertrophy in\\xc2\\xa0vivo. Aging cell vol 15 issue 4 2017 27133203 |
western blots showed that myocardial xbp1s protein was significantly increased in both isoproterenol (iso)-induced and pressure-overload-induced hypertrophic and failing heart compared to normal control. |
2017-06-05 |
2023-01-25 |
human |
| Zaid H Maayah, Hassan N Althurwi, Ahmed A El-Sherbeni, Ghada Abdelhamid, Arno G Siraki, Ayman O S El-Kad. The role of cytochrome P450 1B1 and its associated mid-chain hydroxyeicosatetraenoic acid metabolites in the development of cardiac hypertrophy induced by isoproterenol. Molecular and cellular biochemistry vol 429 issue 1-2 2017 28251434 |
the role of cytochrome p450 1b1 and its associated mid-chain hydroxyeicosatetraenoic acid metabolites in the development of cardiac hypertrophy induced by isoproterenol. |
2017-05-12 |
2023-01-26 |
rat |
| Zaid H Maayah, Hassan N Althurwi, Ahmed A El-Sherbeni, Ghada Abdelhamid, Arno G Siraki, Ayman O S El-Kad. The role of cytochrome P450 1B1 and its associated mid-chain hydroxyeicosatetraenoic acid metabolites in the development of cardiac hypertrophy induced by isoproterenol. Molecular and cellular biochemistry vol 429 issue 1-2 2017 28251434 |
however, the ability of isoproterenol (iso) to induce cardiac hypertrophy through mid-chain hetes has not been investigated yet. |
2017-05-12 |
2023-01-26 |
rat |
| Sophie Clouet, Larissa Di Pietrantonio, Evangelos-Panagiotis Daskalopoulos, Hrag Esfahani, Michael Horckmans, Marion Vanorl\\xc3\\xa9, Anne Lemaire, Jean-Luc Balligand, Christophe Beauloye, Jean-Marie Boeynaems, Didier Commun. Loss of Mouse P2Y6 Nucleotide Receptor Is Associated with Physiological Macrocardia and Amplified Pathological Cardiac Hypertrophy. The Journal of biological chemistry vol 291 issue 30 2017 27231349 |
we then observed that loss of p2y6 receptor enhanced pathological cardiac hypertrophy induced after isoproterenol injection. |
2017-05-08 |
2023-01-25 |
mouse |
| Lei Liu, Chao Wang, Yan Lin, Yuhui Xi, Hong Li, Sa Shi, Hongzhu Li, Weihua Zhang, Yajun Zhao, Ye Tian, Changqing Xu, Lina Wan. Suppression of calcium\\xe2\\x80\\x91sensing receptor ameliorates cardiac hypertrophy through inhibition of autophagy. Molecular medicine reports vol 14 issue 1 2017 27176663 |
isoproterenol (iso) was used to induce cardiac hypertrophy in wistar rats. |
2017-04-06 |
2023-01-25 |
rat |
| Ronghui Han, Futian Tang, Meili Lu, Chonghua Xu, Jin Hu, Meng Mei, Hongxin Wan. Protective effects of Astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol. International immunopharmacology vol 38 issue 2017 27344039 |
protective effects of astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol. |
2017-04-06 |
2023-01-25 |
rat |
| Ronghui Han, Futian Tang, Meili Lu, Chonghua Xu, Jin Hu, Meng Mei, Hongxin Wan. Protective effects of Astragalus polysaccharides against endothelial dysfunction in hypertrophic rats induced by isoproterenol. International immunopharmacology vol 38 issue 2017 27344039 |
the present study was designed to evaluate the protective effect of aps on vascular endothelia in cardiac hypertrophy rats induced by isoproterenol (iso). |
2017-04-06 |
2023-01-25 |
rat |
| Megha Prasad, Jeffrey B Geske, Paul Sorajja, Steve R Ommen, Hartzell V Schaff, Bernard J Gersh, Rick A Nishimur. Hemodynamic changes in systolic and diastolic function during isoproterenol challenge predicts symptomatic response to myectomy in hypertrophic cardiomyopathy with labile obstruction. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions vol 88 issue 6 2017 27062082 |
hemodynamic changes in systolic and diastolic function during isoproterenol challenge predicts symptomatic response to myectomy in hypertrophic cardiomyopathy with labile obstruction. |
2017-03-21 |
2023-01-25 |
Not clear |
| Megha Prasad, Jeffrey B Geske, Paul Sorajja, Steve R Ommen, Hartzell V Schaff, Bernard J Gersh, Rick A Nishimur. Hemodynamic changes in systolic and diastolic function during isoproterenol challenge predicts symptomatic response to myectomy in hypertrophic cardiomyopathy with labile obstruction. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions vol 88 issue 6 2017 27062082 |
we aimed to assess the utility of changes in systolic and diastolic function by isoproterenol challenge in predicting symptom resolution post-myectomy in selected patients with hypertrophic cardiomyopathy (hcm) and labile obstruction. |
2017-03-21 |
2023-01-25 |
Not clear |
| Jing-Jing Liu, Cui-Mei Zhao, Zhi-Gang Li, Yu-Mei Wang, Wei Miao, Xiu-Juan Wu, Wen-Jing Wang, Chang Liu, Duo Wang, Kang Wang, Li Li, Lu-Ying Pen. miR-218 Involvement in Cardiomyocyte Hypertrophy Is Likely through Targeting REST. International journal of molecular sciences vol 17 issue 6 2017 27258257 |
overexpression of mir-218 is sufficient to reduce hypertrophy, whereas the suppression of mir-218 aggravates hypertrophy in primary cardiomyocytes induced by isoprenaline (iso). |
2017-03-17 |
2023-01-25 |
Not clear |