| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Auburn Ramsey, Lokesh Akana, Erina Miyajima, Spencer Douglas, Joshua Gray, Alyssa Rowland, Krishna Deo Sharma, Jianfeng Xu, Jennifer Y Xie, Guo-Lei Zho. CAP1 (cyclase-associated protein 1) mediates the cyclic AMP signals that activate Rap1 in stimulating matrix adhesion of colon cancer cells. Cellular signalling. 2023-01-09. PMID:36621727. |
importantly, depletion of cap1 abolished the stimulatory effects of the camp activators forskolin and isoproterenol, as well as that of epac and pka, on matrix adhesion in both cell types. |
2023-01-09 |
2023-08-14 |
Not clear |
| James T Pearso. Set7 methyltransferase roles in myocardial protection from chronic stressors. Clinical science (London, England : 1979). vol 137. issue 1. 2023-01-05. PMID:36601782. |
recent transcriptome and fourier transform infrared spectroscopy analyses and in vivo assessments of cardiac function by lunardon and colleagues now reveal a clear role of set7 in the regulation of the extracellular matrix composition and cardiac hypertrophy in response to chronic isoproterenol induced cardiac stress. |
2023-01-05 |
2023-08-14 |
Not clear |
| Govindasami Sangeethadevi, Sathibabu Uddandrao V V, Rani Antony Rathinasamy Jansy Isabella, Ganapathy Saravanan, Ponnusamy Ponmurugan, Ponnusamy Chandrasekaran, Singaravel Sengottuvelu, Sasikumar Vadivukkaras. Attenuation of lipid metabolic abnormalities, proinflammatory cytokines, and matrix metalloproteinase expression by biochanin-A in isoproterenol-induced myocardial infarction in rats. Drug and chemical toxicology. 2021-05-07. PMID:33719799. |
in the present study, we assessed the therapeutic potential of biochanin-a (bca) (10 mg/kg bw/day) pretreatment for 30 days on lipid metabolic abnormalities, proinflammatory cytokines and matrix metalloproteinase expression in isoproterenol (iso)-induced myocardial infarction (mi) in rats. |
2021-05-07 |
2023-08-13 |
rat |
| Chengliang Zhang, Yanfeng Zhang, Hong Zhu, Jiajia Hu, Zhongshang Xi. MiR-34a/miR-93 target c-Ski to modulate the proliferaton of rat cardiac fibroblasts and extracellular matrix deposition in vivo and in vitro. Cellular signalling. vol 46. 2019-08-20. PMID:29551367. |
in the present study, we demonstrated that c-ski could ameliorate isoproterenol (iso)-induced rat myocardial fibrosis model and tgf-β1-induced primary rat cardiac fibroblasts' proliferation, as well as extracellular matrix (ecm) deposition. |
2019-08-20 |
2023-08-13 |
human |
| Xinying Zhang, Tiemin Zhang, Jichao Wu, Xiangjing Yu, Dan Zheng, Fan Yang, Ting Li, Lina Wang, Yajun Zhao, Shiyun Dong, Xin Zhong, Songbin Fu, Chang-qing Xu, Fanghao Lu, Wei-hua Zhan. Calcium sensing receptor promotes cardiac fibroblast proliferation and extracellular matrix secretion. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 33. issue 3. 2016-08-01. PMID:24603056. |
the present study investigated whether car played a role in cardiac fibroblast proliferation and extracellular matrix (ecm) secretion, both in cultured rat neonatal cardiac fibroblasts and in a model of cardiac hypertrophy induced by isoproterenol (iso). |
2016-08-01 |
2023-08-12 |
rat |
| Fabio D'Amico, Evangelia Skarmoutsou, Katia Mangano, Grazia Malaponte, Maria Clorinda Mazzarin. Isoproterenol modulates matrix metalloproteinase-2 (MMP-2) and its tissue inhibitor-2 (TIMP-2) in rat parotid gland. Archives of oral biology. vol 58. issue 4. 2013-09-03. PMID:22947212. |
isoproterenol modulates matrix metalloproteinase-2 (mmp-2) and its tissue inhibitor-2 (timp-2) in rat parotid gland. |
2013-09-03 |
2023-08-12 |
rat |
| Ana Paula Nadu, Anderson J Ferreira, Timothy L Reudelhuber, Michael Bader, Robson A S Santo. Reduced isoproterenol-induced renin-angiotensin changes and extracellular matrix deposition in hearts of TGR(A1-7)3292 rats. Journal of the American Society of Hypertension : JASH. vol 2. issue 5. 2013-07-04. PMID:20409916. |
we investigated the expression of specific extracellular matrix (ecm) proteins in cardiac hypertrophy induced by isoproterenol in tgr(a1-7)3292 rats. |
2013-07-04 |
2023-08-12 |
rat |
| Shuangtao Ma, Dachun Yang, Kuiying Wang, Bing Tang, De Li, Yongjian Yan. Cryptotanshinone attenuates isoprenaline-induced cardiac fibrosis in mice associated with upregulation and activation of matrix metalloproteinase-2. Molecular medicine reports. vol 6. issue 1. 2012-09-10. PMID:22505122. |
thus, we investigated the effects of cryptotanshinone on cardiac fibrosis induced by isoprenaline and examined whether cardiac matrix metalloproteinase (mmp)-2 is involved in this process. |
2012-09-10 |
2023-08-12 |
mouse |
| Muneyoshi Okada, Natsuko Kosaka, Yoshikazu Hoshino, Hideyuki Yamawaki, Yukio Har. Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats. Biological & pharmaceutical bulletin. vol 33. issue 9. 2011-07-22. PMID:20823567. |
effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats. |
2011-07-22 |
2023-08-12 |
rat |
| Muneyoshi Okada, Natsuko Kosaka, Yoshikazu Hoshino, Hideyuki Yamawaki, Yukio Har. Effects of captopril and telmisartan on matrix metalloproteinase-2 and -9 expressions and development of left ventricular fibrosis induced by isoprenaline in rats. Biological & pharmaceutical bulletin. vol 33. issue 9. 2011-07-22. PMID:20823567. |
the aim of this study was to clarify the effects of renin-angiotensin system (ras) blockade by captopril, an angiotensin converting enzyme inhibitor, and telmisartan, an angiotensin ii type 1 receptor antagonist, on matrix metalloproteinase (mmp)-2 and mmp-9 expressions and development of left ventricular (lv) fibrosis induced by isoprenaline in rats. |
2011-07-22 |
2023-08-12 |
rat |
| Hong-Jun Peng, De-Zai Dai, Hui Ji, Yin Da. The separate roles of endothelin receptors participate in remodeling of matrix metalloproteinase and connexin 43 of cardiac fibroblasts in maladaptive response to isoproterenol. European journal of pharmacology. vol 634. issue 1-3. 2010-11-01. PMID:20167215. |
the separate roles of endothelin receptors participate in remodeling of matrix metalloproteinase and connexin 43 of cardiac fibroblasts in maladaptive response to isoproterenol. |
2010-11-01 |
2023-08-12 |
rat |
| Yu-si Cheng, De-zai Dai, Yin Da. Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCepsilon in the heart, which are mitigated by endothelin receptor antagonist CPU0213. Acta pharmacologica Sinica. vol 30. issue 8. 2009-10-22. PMID:19597524. |
we hypothesized that dispersed nadph oxidase, protein kinase cepsilon (pkcepsilon), early response gene (erg), and matrix metalloproteinase 9(mmp-9) across the heart by isoproterenol (iso) medication might be mediated by the endothelin (et) - ros pathway. |
2009-10-22 |
2023-08-12 |
Not clear |
| Wen Yin, Peng Zhang, Jing Hui Huang, Quan Yu Zhang, Rong Fan, Juan Li, Jing Jun Zhou, Yu Zhen Hu, Hai Tao Guo, Shu Miao Zhang, Yue Min Wang, Alan David Kaye, Chun Hu Gu, Jin Cheng Liu, Liang Cheng, Qin Cui, Ding Hua Yi, Jian Ming Pe. Stimulation of kappa-opioid receptor reduces isoprenaline-induced cardiac hypertrophy and fibrosis. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19233160. |
the specific extracellular matrix proteins, including type i, type iii collagen and fibronectin, which increased after administration of isoproterenol, were also attenuated by u50,488h. |
2009-07-07 |
2023-08-12 |
rat |
| Erica C Campos, Minna M D Romano, Cibele M Prado, Marcos A Ross. Isoproterenol induces primary loss of dystrophin in rat hearts: correlation with myocardial injury. International journal of experimental pathology. vol 89. issue 5. 2008-12-04. PMID:18808529. |
taking into account that the sarcolemmal integrity is stabilized by the dystrophin-glycoprotein complex (dgc) that connects actin and laminin in contractile machinery and extracellular matrix and by integrins, this study tests the hypothesis that isoproterenol affects sarcolemmal stability through changes in the dgc and integrins. |
2008-12-04 |
2023-08-12 |
rat |
| Erica C Campos, Minna M D Romano, Cibele M Prado, Marcos A Ross. Isoproterenol induces primary loss of dystrophin in rat hearts: correlation with myocardial injury. International journal of experimental pathology. vol 89. issue 5. 2008-12-04. PMID:18808529. |
in conclusion, administration of isoproterenol to rats results in primary loss of dystrophin, the most sensitive among the structural proteins that form the dgc that connects the extracellular matrix and the cytoskeleton in cardiomyocyte. |
2008-12-04 |
2023-08-12 |
rat |
| Keiichiro Kizaki, Muneyoshi Okada, Ryoichi Ito, Kazuki Yoshioka, Kazuyoshi Hashizume, Ken-ichiro Mutoh, Yukio Har. Induction of heparanase gene expression in ventricular myocardium of rats with isoproterenol-induced cardiac hypertrophy. Biological & pharmaceutical bulletin. vol 28. issue 12. 2006-03-09. PMID:16327176. |
gene expression of heparanase, matrix metalloproteinases (mmp)-2 and mmp-9 were examined in ventricles after chronic treatment with isoproterenol (iso) induced cardiac hypertrophy in rats. |
2006-03-09 |
2023-08-12 |
rat |
| Tatyana V Dudnakova, Vladimir L Lakomkin, Valerie G Tsyplenkova, Boris V Shekhonin, Vladimir P Shirinsky, Valeri I Kapelk. Alterations in myocardial ultrastructure and protein expression after a single injection of isoproterenol. Molecular and cellular biochemistry. vol 252. issue 1-2. 2004-06-03. PMID:14577591. |
obtained results indicate that even a single injection of isoproterenol creates long lasting structural alterations in cardiac muscle accompanied by the increased expression of extracellular matrix proteins and several sarcoplasmic proteins apparently involved in hypertrophic response of cardiomyocytes. |
2004-06-03 |
2023-08-12 |
rat |
| Tatyana V Dudnakova, Vladimir L Lakomkin, Valerie G Tsyplenkova, Boris V Shekhonin, Vladimir P Shirinsky, Valeri I Kapelk. Alterations in myocardial ultrastructure and protein expression after a single injection of isoproterenol. Molecular and cellular biochemistry. vol 252. issue 1-2. 2004-06-03. PMID:14577591. |
the smaller dosage of isoproterenol (10 mg/kg) rendered no significant damage in the acute postinjection period but 3 weeks later it induced the thickening of extracellular matrix around cardiac cells and the increase in krp and tubulin content by 26 and 32%, correspondingly. |
2004-06-03 |
2023-08-12 |
rat |
| R L Broverman, K H Nguyen, A da Silveira, L L Brinkley, S P Macauley, T Zeng, H Yamamoto, R W Tarnuzzer, G S Schultz, M Kerr, M G Humphreys-Behe. Changes in the expression of extracellular matrix (ECM) and matrix metalloproteinases (MMP) of proliferating rat parotid acinar cells. Journal of dental research. vol 77. issue 7. 1998-07-30. PMID:9663435. |
daily administration of the broad-spectrum matrix metalloproteinase inhibitor galardin for 3 days in combination with isoproterenol resulted in enhanced gland hypertrophy compared with that produced by isoproterenol alone. |
1998-07-30 |
2023-08-12 |
rat |
| M Yoshiyama, K Takeuchi, S Kim, A Hanatani, T Omura, I Toda, K Akioka, M Teragaki, H Iwao, J Yoshikaw. Effect of manidipine hydrochloride, a calcium antagonist, on isoproterenol-induced left ventricular hypertrophy. Japanese circulation journal. vol 62. issue 1. 1998-06-16. PMID:9559417. |
thus, manidipine hydrochloride prevented cardiac hypertrophy and changes in the expression of genes for anp and interstitial components of extracellular matrix induced by isoproterenol. |
1998-06-16 |
2023-08-12 |
rat |