| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dara G Ghahremani, Jean-Baptiste F Pochon, Maylen Perez Diaz, Rachel F Tyndale, Andy C Dean, Edythe D Londo. Nicotine dependence and insula subregions: functional connectivity and cue-induced activation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol issue 2023 36869233 |
nicotine dependence was negatively correlated with connectivity of the left and right dorsal, and left ventral anterior insula with regions within the superior parietal lobule (spl), including the left precuneus. |
2023-03-03 |
2023-03-06 |
human |
| Dara G Ghahremani, Jean-Baptiste F Pochon, Maylen Perez Diaz, Rachel F Tyndale, Andy C Dean, Edythe D Londo. Nicotine dependence and insula subregions: functional connectivity and cue-induced activation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol issue 2023 36869233 |
cue-induced activation in the left dorsal anterior insula was positively associated with nicotine dependence and negatively associated with rsfc of the same region with spl, suggesting that craving-related responsivity in this subregion was greater among participants who were more dependent. |
2023-03-03 |
2023-03-06 |
human |
| Dara G Ghahremani, Jean-Baptiste F Pochon, Maylen Perez Diaz, Rachel F Tyndale, Andy C Dean, Edythe D Londo. Nicotine dependence and insula subregions: functional connectivity and cue-induced activation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol issue 2023 36869233 |
nicotine dependence and insula subregions: functional connectivity and cue-induced activation. |
2023-03-03 |
2023-03-06 |
human |
| Dara G Ghahremani, Jean-Baptiste F Pochon, Maylen Perez Diaz, Rachel F Tyndale, Andy C Dean, Edythe D Londo. Nicotine dependence and insula subregions: functional connectivity and cue-induced activation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol issue 2023 36869233 |
no relationship between posterior insula connectivity and nicotine dependence was found. |
2023-03-03 |
2023-03-06 |
human |
| Hussein Ghareh, Isis Alonso-Lozares, Dustin Schetters, Rae J Herman, Tim S Heistek, Yvar Van Mourik, Philip Jean-Richard-Dit-Bressel, Gerald Zernig, Huibert D Mansvelder, Taco J De Vries, Nathan J Marchan. Role of anterior insula cortex in context-induced relapse of nicotine-seeking. eLife vol 11 issue 2022 35536612 |
the insular cortex (ic) is thought to be a critical substrate of nicotine addiction and relapse. |
2022-05-10 |
2023-01-27 |
rat |
| Hiroki Toyoda, Kohei Kog. Nicotine Exposure during Adolescence Leads to Changes of Synaptic Plasticity and Intrinsic Excitability of Mice Insular Pyramidal Cells at Later Life. International journal of molecular sciences vol 23 issue 1 2022 35008455 |
however, it has not been addressed whether and how nicotine exposure during adolescence alters these synaptic events and intrinsic excitability in the insular cortex in adulthood. |
2022-01-11 |
2023-01-26 |
mouse |
| Hiroki Toyoda, Kohei Kog. Nicotine Exposure during Adolescence Leads to Changes of Synaptic Plasticity and Intrinsic Excitability of Mice Insular Pyramidal Cells at Later Life. International journal of molecular sciences vol 23 issue 1 2022 35008455 |
to address this question, we performed whole-cell patch-clamp recordings to examine the effects of adolescent nicotine exposure on synaptic transmission, plasticity and intrinsic excitability in layer v pyramidal neurons (pns) of the mice insular cortex five weeks after the treatment. |
2022-01-11 |
2023-01-26 |
mouse |
| Hiroki Toyoda, Kohei Kog. Nicotine Exposure during Adolescence Leads to Changes of Synaptic Plasticity and Intrinsic Excitability of Mice Insular Pyramidal Cells at Later Life. International journal of molecular sciences vol 23 issue 1 2022 35008455 |
our data indicate that adolescent nicotine exposure enhances synaptic transmission, plasticity and intrinsic excitability in layer v pns of the mice insular cortex at later life, which might contribute to severe nicotine dependence in adulthood. |
2022-01-11 |
2023-01-26 |
mouse |
| Gregory C Loney, Christopher P King, Paul J Meye. Systemic nicotine enhances opioid self-administration and modulates the formation of opioid-associated memories partly through actions within the insular cortex. Scientific reports vol 11 issue 1 2021 33558613 |
systemic nicotine enhances opioid self-administration and modulates the formation of opioid-associated memories partly through actions within the insular cortex. |
2021-11-11 |
2023-01-26 |
Not clear |
| Gregory C Loney, Christopher P King, Paul J Meye. Systemic nicotine enhances opioid self-administration and modulates the formation of opioid-associated memories partly through actions within the insular cortex. Scientific reports vol 11 issue 1 2021 33558613 |
given the involvement of the insula in the maintenance of substance abuse, its importance in nicotine addiction, and findings that insular inactivation impairs contextual drug conditioning, we examined whether nicotine administered directly to the insula could recapitulate the effects of systemic nicotine. |
2021-11-11 |
2023-01-26 |
Not clear |
| Gregory C Loney, Christopher P King, Paul J Meye. Systemic nicotine enhances opioid self-administration and modulates the formation of opioid-associated memories partly through actions within the insular cortex. Scientific reports vol 11 issue 1 2021 33558613 |
in conclusion, these data demonstrate that nicotine facilitates opioid intake and is partly acting within the insular cortex to obfuscate aversive opiate memories while potentiating approach to morphine-associated stimuli at higher doses. |
2021-11-11 |
2023-01-26 |
Not clear |
| Maylen Perez Diaz, Jean-Baptiste Pochon, Dara G Ghahremani, Andy C Dean, Paul Faulkner, Nicole Petersen, Rachel F Tyndale, Andrea Donis, Diana Paez, Citlaly Cahuantzi, Gerhard S Hellemann, Edythe D Londo. Sex Differences in the Association of Cigarette Craving With Insula Structure. The international journal of neuropsychopharmacology vol 24 issue 8 2021 33830218 |
because cigarette craving is associated with nicotine dependence and structure of the insula, this study addressed whether a person's sex influences these associations. |
2021-10-06 |
2023-01-26 |
Not clear |
| Chao Wang, Shuyue Wang, Peiyu Huang, Zhujing Shen, Wei Qian, Xiao Luo, Kaicheng Li, Qingze Zeng, Quanquan Gu, Hualiang Yu, Yihong Yang, Minming Zhan. Abnormal white matter tracts of insula in smokers. Brain imaging and behavior vol 15 issue 4 2021 32974850 |
the insula, a cortical region that is thought to play a central role in this reward circuitry, has been implicated in the maintenance of nicotine addiction. |
2021-09-06 |
2023-01-26 |
Not clear |
| Chao Wang, Shuyue Wang, Peiyu Huang, Zhujing Shen, Wei Qian, Xiao Luo, Kaicheng Li, Qingze Zeng, Quanquan Gu, Hualiang Yu, Yihong Yang, Minming Zhan. Abnormal white matter tracts of insula in smokers. Brain imaging and behavior vol 15 issue 4 2021 32974850 |
however, it remains largely unclear about the white matter (wm) microstructural alterations of insula in nicotine addiction and whether the wm alterations of insula could predict smoking cessation outcomes. |
2021-09-06 |
2023-01-26 |
Not clear |
| Kainan S Wang, Maya Zegel, Elena Molokotos, Lauren V Moran, David P Olson, Diego A Pizzagalli, Amy C Jane. The acute effects of nicotine on corticostriatal responses to distinct phases of reward processing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol 45 issue 7 2021 31931509 |
during outcome, nicotine reduced nacc functional connectivity with cortical regions including the anterior cingulate cortex, orbitofrontal cortex, and insula. |
2021-05-27 |
2023-01-26 |
Not clear |
| Irene Perini, Robin K\\xc3\\xa4mpe, Theodor Arlestig, Hanna Karlsson, Andreas L\\xc3\\xb6fberg, Michal Pietrzak, Abraham Zangen, Markus Heili. Repetitive transcranial magnetic stimulation targeting the insular cortex for reduction of heavy drinking in treatment-seeking alcohol-dependent subjects: a randomized controlled trial. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol 45 issue 5 2021 31711065 |
insula responses to drug cues are correlated with cravings, and lesions in this area reduce nicotine seeking. |
2021-03-30 |
2023-01-26 |
human |
| E Lesage, M T Sutherland, T J Ross, B J Salmeron, E A Stei. Nicotine dependence (trait) and acute nicotinic stimulation (state) modulate attention but not inhibitory control: converging fMRI evidence from Go-Nogo and Flanker tasks. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol 45 issue 5 2021 31995811 |
go-nogo fmri results showed decreased inhibition-related neural activity in right anterior insula and right putamen in smokers and decreased dorsal anterior cingulate cortex activity on nicotine across groups. |
2021-03-30 |
2023-01-26 |
Not clear |
| Amy C Janes, Nathan L Krantz, Lisa D Nickerson, Blaise B Frederick, Scott E Luka. Craving and Cue Reactivity in Nicotine-Dependent Tobacco Smokers Is Associated With Different Insula Networks. Biological psychiatry. Cognitive neuroscience and neuroimaging vol 5 issue 1 2020 31706906 |
the insula has a well-established role in nicotine dependence and is a node of the salience network, which integrates internal and external information to guide behavior. |
2020-12-04 |
2023-01-26 |
Not clear |
| Robin N Perry, Hera E Schlagintweit, Christine Darredeau, Carl Helmick, Aaron J Newman, Kimberley P Good, Sean P Barret. The impacts of actual and perceived nicotine administration on insula functional connectivity with the anterior cingulate cortex and nucleus accumbens. Journal of psychopharmacology (Oxford, England) vol 33 issue 12 2020 31542980 |
changes in resting state functional connectivity between the insula and dorsal anterior cingulate cortex as well as between the insula and nucleus accumbens have been linked to nicotine withdrawal and/or administration. |
2020-08-14 |
2023-01-26 |
Not clear |
| Hiroki Toyod. Nicotinic activity layer specifically modulates synaptic potentiation in the mouse insular cortex. The European journal of neuroscience vol 50 issue 3 2020 29405451 |
nicotinic acetylcholine receptors (nachrs) in the insular cortex play an important role in nicotine addiction, but its cellular and synaptic mechanisms underlying nicotine addiction still remain unresolved. |
2020-08-07 |
2023-01-26 |
mouse |