| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Kuroda, N Schweighofer, M Kawat. Exploration of signal transduction pathways in cerebellar long-term depression by kinetic simulation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 15. 2001-08-16. PMID:11466441. |
to address this issue, we built a new diagram of signal transduction pathways and developed a computational model of kinetic simulation for the phosphorylation of ampa receptors, known as a key step for expressing cerebellar ltd. |
2001-08-16 |
2023-08-12 |
Not clear |
| S Ishiuchi, K Tsuzuki, N Yamada, H Okado, A Miwa, H Kuromi, H Yokoo, Y Nakazato, T Sasaki, S Ozaw. Extension of glial processes by activation of Ca2+-permeable AMPA receptor channels. Neuroreport. vol 12. issue 4. 2001-08-02. PMID:11277576. |
ampa type-glutamate receptor channels (ampars) assembled without the glur2 (glur-b) subunit are characterized by high ca2+ permeability, and are expressed abundantly in cerebellar bergmann glial cells. |
2001-08-02 |
2023-08-12 |
rat |
| H Hira. Modification of AMPA receptor clustering regulates cerebellar synaptic plasticity. Neuroscience research. vol 39. issue 3. 2001-06-14. PMID:11248365. |
modification of ampa receptor clustering regulates cerebellar synaptic plasticity. |
2001-06-14 |
2023-08-12 |
Not clear |
| H Hira. Modification of AMPA receptor clustering regulates cerebellar synaptic plasticity. Neuroscience research. vol 39. issue 3. 2001-06-14. PMID:11248365. |
this article focuses on molecular mechanisms regulating the synaptic ampa receptor clustering in purkinje cells, which could underlie the expression of cerebellar ltd. synaptic ampa receptor clusters in dendritic spines of purkinje cells are disrupted upon protein kinase c (pkc)-mediated phosphorylation of serine 880 in the c-terminal domain of glur2. |
2001-06-14 |
2023-08-12 |
Not clear |
| H Hira. Modification of AMPA receptor clustering regulates cerebellar synaptic plasticity. Neuroscience research. vol 39. issue 3. 2001-06-14. PMID:11248365. |
based on these findings, a model for the expression of cerebellar ltd is proposed, in which a decrease in the number of postsynaptic ampa receptors, initiated by phosphorylation of glur2 serine 880, is the major mechanism underlying cerebellar ltd. |
2001-06-14 |
2023-08-12 |
Not clear |
| M Iino, K Goto, W Kakegawa, H Okado, M Sudo, S Ishiuchi, A Miwa, Y Takayasu, I Saito, K Tsuzuki, S Ozaw. Glia-synapse interaction through Ca2+-permeable AMPA receptors in Bergmann glia. Science (New York, N.Y.). vol 292. issue 5518. 2001-05-31. PMID:11340205. |
notably, bergmann glial cells in the cerebellum have ca2+-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa)-type glutamate receptors (ampars) assembled without the glur2 subunit. |
2001-05-31 |
2023-08-12 |
Not clear |
| R A Al-Hallaq, R P Yasuda, B B Wolf. Enrichment of N-methyl-D-aspartate NR1 splice variants and synaptic proteins in rat postsynaptic densities. Journal of neurochemistry. vol 77. issue 1. 2001-05-03. PMID:11279267. |
additionally, cerebellar but not cortical psds exhibited significantly lower enrichment of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) glur1. |
2001-05-03 |
2023-08-12 |
rat |
| J Keifer, M T Car. Immunocytochemical localization of glutamate receptor subunits in the brain stem and cerebellum of the turtle Chrysemys picta. The Journal of comparative neurology. vol 427. issue 3. 2001-01-04. PMID:11054706. |
the regional distribution of ionotropic (ampa and nmda) and metabotropic (mglur1alpha) glutamate receptor subunits was examined in the brain stem and cerebellum of the pond turtle, chrysemys picta, by using immunocytochemistry and light microscopy. |
2001-01-04 |
2023-08-12 |
rat |
| J Xia, H J Chung, C Wihler, R L Huganir, D J Linde. Cerebellar long-term depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins. Neuron. vol 28. issue 2. 2001-01-04. PMID:11144359. |
cerebellar ltd requires activation of pkc and is expressed, at least in part, as postsynaptic ampa receptor internalization. |
2001-01-04 |
2023-08-12 |
Not clear |
| I G Sil'ki. [Mechanisms of modification of excitatory and inhibitory inputs in various neurons of olivary-cerebellar network]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 50. issue 3. 2000-09-25. PMID:10923375. |
the mechanism is based on a postulate that phosphorylation/dephosphorylation of ampa (gabaa) receptors on cerebellar cells causes the ltp/ltd of excitatory (ltd/ltp of inhibitory) transmission. |
2000-09-25 |
2023-08-12 |
Not clear |
| C Strazielle, R Lalonde, T A Reade. Autoradiography of glutamate receptor binding in adult Lurcher mutant mice. Journal of neuropathology and experimental neurology. vol 59. issue 8. 2000-08-30. PMID:10952061. |
in cerebellum, there were postsynaptic ampa and metabotropic receptors on purkinje cells, postsynaptic nmda receptors on granule cells, as well as ka receptors on granule cells or on parallel fibers. |
2000-08-30 |
2023-08-12 |
mouse |
| I G Sil'ki. [Unified postsynaptic mechanism of plasticity in the striatum, neocortex, hippocampus, and cerebellum]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 86. issue 5. 2000-08-08. PMID:10885014. |
the unitary postsynaptic mechanism of plasticity in striatum, neocortex, hippocampus and cerebellum involves the ltp/ltd excitation as result of ampa and nmda receptor phosphorylation/dephosphorylation, while the ltp/ltd of inhibition is the result of the gaba receptor phosphorylation/dephosphorylation. |
2000-08-08 |
2023-08-12 |
Not clear |
| S Matsuda, T Launey, S Mikawa, H Hira. Disruption of AMPA receptor GluR2 clusters following long-term depression induction in cerebellar Purkinje neurons. The EMBO journal. vol 19. issue 12. 2000-08-07. PMID:10856222. |
here, using cultured purkinje cells, we show that stimulations inducing cerebellar ltd cause phosphorylation of ser880 in the intracellular c-terminal domain of the ampa receptor subunit glur2. |
2000-08-07 |
2023-08-12 |
Not clear |
| S Satake, F Saitow, J Yamada, S Konish. Synaptic activation of AMPA receptors inhibits GABA release from cerebellar interneurons. Nature neuroscience. vol 3. issue 6. 2000-07-13. PMID:10816310. |
synaptic activation of ampa receptors inhibits gaba release from cerebellar interneurons. |
2000-07-13 |
2023-08-12 |
Not clear |
| S Satake, F Saitow, J Yamada, S Konish. Synaptic activation of AMPA receptors inhibits GABA release from cerebellar interneurons. Nature neuroscience. vol 3. issue 6. 2000-07-13. PMID:10816310. |
dual ampa receptor-mediated functions of excitation and disinhibition may ensure transmission of cerebellar cf signals controlling sensorimotor coordination. |
2000-07-13 |
2023-08-12 |
Not clear |
| L G Magazani. Blockade of ion channels as an approach to studying AMPA receptor subtypes. Neuroscience and behavioral physiology. vol 30. issue 1. 2000-06-02. PMID:10768369. |
differences in the subunit composition of ampa receptors involved in glutamatergic synaptic inputs to efferent (main) neurons and interneurons are discussed with reference to neurons isolated from the hippocampus, striatum, and cerebellum. |
2000-06-02 |
2023-08-12 |
Not clear |
| Y T Wang, D J Linde. Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis. Neuron. vol 25. issue 3. 2000-05-02. PMID:10774731. |
while cerebellar ltd is expressed as a selective modification of postsynaptic ampa receptors, this might involve changes in receptor number/distribution, unitary conductance, kinetics, or glutamate affinity. |
2000-05-02 |
2023-08-12 |
Not clear |
| Y T Wang, D J Linde. Expression of cerebellar long-term depression requires postsynaptic clathrin-mediated endocytosis. Neuron. vol 25. issue 3. 2000-05-02. PMID:10774731. |
these findings suggest that the expression of cerebellar ltd requires clathrin-mediated internalization of postsynaptic ampa receptors. |
2000-05-02 |
2023-08-12 |
Not clear |
| T C Smith, L Y Wang, J R How. Heterogeneous conductance levels of native AMPA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 20. issue 6. 2000-04-03. PMID:10704481. |
using whole-cell and outside-out patch-clamp recordings from granule cells in acute cerebellar slices, we found that migrating granule cells begin to express ampa receptors before they arrive in the internal granule cell layer and receive synaptic input. |
2000-04-03 |
2023-08-12 |
Not clear |
| G Yang, G Chen, T J Ebner, C Iadecol. Nitric oxide is the predominant mediator of cerebellar hyperemia during somatosensory activation in rats. The American journal of physiology. vol 277. issue 6. 2000-01-19. PMID:10600924. |
in particular, we sought to determine whether stimulation of the perioral region increases cerebellar blood flow (bfcrb) in crus ii and, if so, whether the response depends on activation of 2-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa)-kainate receptors and nitric oxide (no) production. |
2000-01-19 |
2023-08-12 |
rat |