All Relations between \u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and cerebellum

Publication Sentence Publish Date Extraction Date Species
Daniela Laricchiuta, Virve Cavallucci, Debora Cutuli, Paola De Bartolo, Paola Caporali, Francesca Foti, Carsten Finke, Marcello D'Amelio, Mario Manto, Laura Petrosin. Effects of Anti-NMDA Antibodies on Functional Recovery and Synaptic Rearrangement Following Hemicerebellectomy. Neuromolecular medicine. vol 18. issue 2. 2018-05-10. PMID:27027521. the molecular analyses indicated that cerebellar compensatory processes were related to a relevant rearrangement of glutamatergic synapses (nmda and ampa receptors and other glutamatergic components) along the entire cortico-cerebellar network. 2018-05-10 2023-08-13 rat
Andrea Cabrera-Pastor, Lucas Taoro-González, Esperanza López-Merino, Ferran Celma, Marta Llansola, Vicente Felip. Chronic hyperammonemia alters in opposite ways membrane expression of GluA1 and GluA2 AMPA receptor subunits in cerebellum. Molecular mechanisms involved. Biochimica et biophysica acta. Molecular basis of disease. vol 1864. issue 1. 2018-03-26. PMID:29107806. chronic hyperammonemia alters in opposite ways membrane expression of glua1 and glua2 ampa receptor subunits in cerebellum. 2018-03-26 2023-08-13 rat
Andrea Cabrera-Pastor, Lucas Taoro-González, Esperanza López-Merino, Ferran Celma, Marta Llansola, Vicente Felip. Chronic hyperammonemia alters in opposite ways membrane expression of GluA1 and GluA2 AMPA receptor subunits in cerebellum. Molecular mechanisms involved. Biochimica et biophysica acta. Molecular basis of disease. vol 1864. issue 1. 2018-03-26. PMID:29107806. hyperammonemia in rats affects differently high- and low-affinity ampa receptors (ampars) in cerebellum. 2018-03-26 2023-08-13 rat
Zhengping Jia, Graham L Collingridg. Learning about Synaptic GluA3. Neuron. vol 93. issue 2. 2017-10-26. PMID:28103474. (2017) reveal a critical role for the ampa receptor subunit glua3 in cerebellar synaptic plasticity and motor learning in mice. 2017-10-26 2023-08-13 mouse
Akihiko S Kato, Kevin D Burris, Kevin M Gardinier, Douglas L Gernert, Warren J Porter, Jon Reel, Chunjin Ding, Yuan Tu, Douglas A Schober, Matthew R Lee, Beverly A Heinz, Thomas E Fitch, Scott D Gleason, John T Catlow, Hong Yu, Stephen M Fitzjohn, Francesca Pasqui, He Wang, Yuewei Qian, Emanuele Sher, Ruud Zwart, Keith A Wafford, Kurt Rasmussen, Paul L Ornstein, John T R Isaac, Eric S Nisenbaum, David S Bredt, Jeffrey M Witki. Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism. Nature medicine. vol 22. issue 12. 2017-08-08. PMID:27820603. we hypothesized that blockade of forebrain ampa receptors without blocking cerebellar ampa receptors would be antiepileptic and devoid of motor impairment. 2017-08-08 2023-08-13 mouse
Akihiko S Kato, Kevin D Burris, Kevin M Gardinier, Douglas L Gernert, Warren J Porter, Jon Reel, Chunjin Ding, Yuan Tu, Douglas A Schober, Matthew R Lee, Beverly A Heinz, Thomas E Fitch, Scott D Gleason, John T Catlow, Hong Yu, Stephen M Fitzjohn, Francesca Pasqui, He Wang, Yuewei Qian, Emanuele Sher, Ruud Zwart, Keith A Wafford, Kurt Rasmussen, Paul L Ornstein, John T R Isaac, Eric S Nisenbaum, David S Bredt, Jeffrey M Witki. Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism. Nature medicine. vol 22. issue 12. 2017-08-08. PMID:27820603. taking advantage of an ampa receptor auxiliary protein, tarp γ-8, which is selectively expressed in the forebrain and modulates the pharmacological properties of ampa receptors, we discovered that ly3130481 selectively antagonized recombinant and native ampa receptors containing γ-8, but not γ-2 (cerebellum) or other tarp members. 2017-08-08 2023-08-13 mouse
Akihiko S Kato, Kevin D Burris, Kevin M Gardinier, Douglas L Gernert, Warren J Porter, Jon Reel, Chunjin Ding, Yuan Tu, Douglas A Schober, Matthew R Lee, Beverly A Heinz, Thomas E Fitch, Scott D Gleason, John T Catlow, Hong Yu, Stephen M Fitzjohn, Francesca Pasqui, He Wang, Yuewei Qian, Emanuele Sher, Ruud Zwart, Keith A Wafford, Kurt Rasmussen, Paul L Ornstein, John T R Isaac, Eric S Nisenbaum, David S Bredt, Jeffrey M Witki. Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism. Nature medicine. vol 22. issue 12. 2017-08-08. PMID:27820603. we also observed antagonism of ampa receptors expressed in hippocampal, but not cerebellar, tissue from an patient with epilepsy. 2017-08-08 2023-08-13 mouse
Lei Han, Shuhua Mu, Zhendan He, Zhiwei Wang, Junle Qu, Wencai Ye, Jian Zhan. CNQX facilitates inhibitory synaptic transmission in rat hypoglossal nucleus. Brain research. vol 1637. 2017-01-24. PMID:26902496. during the past two decades, studies had demonstrated that cnqx could partially activate ampa receptors that are located on the hippocampal and cerebellar interneurons, thus subsequently leading to the facilitation of inhibitory transmission. 2017-01-24 2023-08-13 rat
Andrea Cabrera-Pastor, Lucas Taoro, Marta Llansola, Vicente Felip. Roles of the NMDA Receptor and EAAC1 Transporter in the Modulation of Extracellular Glutamate by Low and High Affinity AMPA Receptors in the Cerebellum in Vivo: Differential Alteration in Chronic Hyperammonemia. ACS chemical neuroscience. vol 6. issue 12. 2016-09-21. PMID:26428532. roles of the nmda receptor and eaac1 transporter in the modulation of extracellular glutamate by low and high affinity ampa receptors in the cerebellum in vivo: differential alteration in chronic hyperammonemia. 2016-09-21 2023-08-13 rat
Andrea Cabrera-Pastor, Lucas Taoro, Marta Llansola, Vicente Felip. Roles of the NMDA Receptor and EAAC1 Transporter in the Modulation of Extracellular Glutamate by Low and High Affinity AMPA Receptors in the Cerebellum in Vivo: Differential Alteration in Chronic Hyperammonemia. ACS chemical neuroscience. vol 6. issue 12. 2016-09-21. PMID:26428532. the roles of high- and low-affinity ampa receptors in modulating extracellular glutamate in the cerebellum remain unclear. 2016-09-21 2023-08-13 rat
Andrea Cabrera-Pastor, Lucas Taoro, Marta Llansola, Vicente Felip. Roles of the NMDA Receptor and EAAC1 Transporter in the Modulation of Extracellular Glutamate by Low and High Affinity AMPA Receptors in the Cerebellum in Vivo: Differential Alteration in Chronic Hyperammonemia. ACS chemical neuroscience. vol 6. issue 12. 2016-09-21. PMID:26428532. the aims were to assess by in vivo microdialysis (a) the effects of high- and low-affinity ampa receptor activation on extracellular glutamate in the cerebellum; (b) whether chronic hyperammonemia alters extracellular glutamate modulation by high- and/or low-affinity ampa receptors; and (c) the contribution of nmda receptors and eaac1 transporter to ampa-induced changes in extracellular glutamate. 2016-09-21 2023-08-13 rat
Chiara Cervetto, Daniela Frattaroli, Arianna Venturini, Mario Passalacqua, Mario Nobile, Susanna Alloisio, Carlo Tacchetti, Guido Maura, Luigi Francesco Agnati, Manuela Marcol. Calcium-permeable AMPA receptors trigger vesicular glutamate release from Bergmann gliosomes. Neuropharmacology. vol 99. 2016-08-30. PMID:26260232. to better understand roles for the bergmann ampa receptors, herein we investigate on gliotransmitter release and ca2+ signals in isolated bergmann glia processes obtained from adult rat cerebellum. 2016-08-30 2023-08-13 rat
Chiara Cervetto, Daniela Frattaroli, Arianna Venturini, Mario Passalacqua, Mario Nobile, Susanna Alloisio, Carlo Tacchetti, Guido Maura, Luigi Francesco Agnati, Manuela Marcol. Calcium-permeable AMPA receptors trigger vesicular glutamate release from Bergmann gliosomes. Neuropharmacology. vol 99. 2016-08-30. PMID:26260232. we found that: 1) the rat cerebellar purified astrocyte processes (gliosomes) expressed astrocytic and bergmann markers and exhibited negligible contamination by nerve terminals, microglia, or oligodendrocytes; 2) activation of ca2+-permeable ampa receptors caused ca2+ signals in the processes, and the release of glutamate from the processes; 3) effectiveness of rose bengal, trypan blue or bafilomycin a1, indicated that activation of the ampa receptors evoked vesicular glutamate release. 2016-08-30 2023-08-13 rat
Chiara Cervetto, Daniela Frattaroli, Arianna Venturini, Mario Passalacqua, Mario Nobile, Susanna Alloisio, Carlo Tacchetti, Guido Maura, Luigi Francesco Agnati, Manuela Marcol. Calcium-permeable AMPA receptors trigger vesicular glutamate release from Bergmann gliosomes. Neuropharmacology. vol 99. 2016-08-30. PMID:26260232. cerebellar purified nerve terminals appeared devoid of glutamate-releasing ca2+-permeable ampa receptors, indicating that neuronal contamination may not be the source of the signals detected. 2016-08-30 2023-08-13 rat
Chiara Cervetto, Daniela Frattaroli, Arianna Venturini, Mario Passalacqua, Mario Nobile, Susanna Alloisio, Carlo Tacchetti, Guido Maura, Luigi Francesco Agnati, Manuela Marcol. Calcium-permeable AMPA receptors trigger vesicular glutamate release from Bergmann gliosomes. Neuropharmacology. vol 99. 2016-08-30. PMID:26260232. the findings would add a new role for a well-known bergmann target for glutamate (the ca2+-permeable ampa receptors) and a new actor (the gliotransmitter glutamate) at the cerebellar excitatory synapses onto purkinje cells. 2016-08-30 2023-08-13 rat
Dolores Vazquez-Sanroman, Ketty Leto, Miguel Cerezo-Garcia, María Carbo-Gas, Carla Sanchis-Segura, Daniela Carulli, Ferdinando Rossi, Marta Mique. The cerebellum on cocaine: plasticity and metaplasticity. Addiction biology. vol 20. issue 5. 2016-06-01. PMID:25619460. in the present study, we investigated the effects of a chronic cocaine treatment on molecular and structural plasticity in the cerebellum, including bdnf, d3 dopamine receptors, Δfosb, the glu2 ampa receptor subunit, structural modifications in purkinje neurons and, finally, the evaluation of perineuronal nets (pnns) in the projection neurons of the medial nucleus, the output of the cerebellar vermis. 2016-06-01 2023-08-13 mouse
Andrew R Gallimore, A Radu Aricescu, Michisuke Yuzaki, Radu Calinesc. A Computational Model for the AMPA Receptor Phosphorylation Master Switch Regulating Cerebellar Long-Term Depression. PLoS computational biology. vol 12. issue 1. 2016-05-11. PMID:26807999. a computational model for the ampa receptor phosphorylation master switch regulating cerebellar long-term depression. 2016-05-11 2023-08-13 Not clear
Attila D Kovács, Caitlin Hof, David A Pearc. Abnormally increased surface expression of AMPA receptors in the cerebellum, cortex and striatum of Cln3(-/-) mice. Neuroscience letters. vol 607. 2016-03-21. PMID:26375929. abnormally increased surface expression of ampa receptors in the cerebellum, cortex and striatum of cln3(-/-) mice. 2016-03-21 2023-08-13 mouse
Attila D Kovács, Caitlin Hof, David A Pearc. Abnormally increased surface expression of AMPA receptors in the cerebellum, cortex and striatum of Cln3(-/-) mice. Neuroscience letters. vol 607. 2016-03-21. PMID:26375929. in surface cross-linked brain samples, western blotting for ampa receptor subunits revealed significantly increased surface levels of glua1 and glua2 in the cerebellum, and of glua2 in the cortex and striatum of cln3(-/-) mice as compared to wt mice. 2016-03-21 2023-08-13 mouse
Danielle E Harlow, Katherine E Saul, Hitoshi Komuro, Wendy B Mackli. Myelin Proteolipid Protein Complexes with αv Integrin and AMPA Receptors In Vivo and Regulates AMPA-Dependent Oligodendrocyte Progenitor Cell Migration through the Modulation of Cell-Surface GluR2 Expression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 34. 2015-11-24. PMID:26311781. we found that in wild-type cerebellum, plp associates with αv integrin and the calcium-impermeable glur2 subunit of the ampa receptor, but in mice lacking plp, αv integrin did not associate with glur2. 2015-11-24 2023-08-13 mouse