| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Martine Hamann, David J Rossi, Claudia Mohr, Adriana L Andrade, David Attwel. The electrical response of cerebellar Purkinje neurons to simulated ischaemia. Brain : a journal of neurology. vol 128. issue Pt 10. 2005-12-29. PMID:16123143. |
these data suggest that, in cerebellar ischaemia, the dominant cause of the electrophysiological dysfunction of purkinje cells is an activation of purkinje cell ampa receptors. |
2005-12-29 |
2023-08-12 |
mouse |
| Jun-ichi Tanaka, Masanori Matsuzaki, Etsuko Tarusawa, Akiko Momiyama, Elek Molnar, Haruo Kasai, Ryuichi Shigemot. Number and density of AMPA receptors in single synapses in immature cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 4. 2005-08-31. PMID:15673659. |
number and density of ampa receptors in single synapses in immature cerebellum. |
2005-08-31 |
2023-08-12 |
rat |
| Nikolas Offenhauser, Kirsten Thomsen, Kirsten Caesar, Martin Lauritze. Activity-induced tissue oxygenation changes in rat cerebellar cortex: interplay of postsynaptic activation and blood flow. The Journal of physiology. vol 565. issue Pt 1. 2005-08-16. PMID:15774524. |
our findings suggest an inverse relationship between negative p(tiss,o2) and cbf responses, and provide direct in vivo evidence for a tight coupling between activity in postsynaptic ampa receptors and cerebellar oxygen consumption. |
2005-08-16 |
2023-08-12 |
rat |
| Shih-Chun Lin, Jojanneke H J Huck, J David B Roberts, Wendy B Macklin, Peter Somogyi, Dwight E Bergle. Climbing fiber innervation of NG2-expressing glia in the mammalian cerebellum. Neuron. vol 46. issue 5. 2005-08-01. PMID:15924863. |
here, we show that release of glutamate from climbing fiber (cf) axons produces ampa receptor currents with rapid kinetics in these ng2-immunoreactive glial cells (ng2+ cells) in cerebellar slices. |
2005-08-01 |
2023-08-12 |
Not clear |
| Luc Pellerin, Pierre J Magistrett. Ampakine CX546 bolsters energetic response of astrocytes: a novel target for cognitive-enhancing drugs acting as alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor modulators. Journal of neurochemistry. vol 92. issue 3. 2005-06-24. PMID:15659236. |
ampa itself did not stimulate aerobic glycolysis, but in the presence of cx546, a strong enhancement of glucose utilization and lactate production was obtained in cortical, hippocampal and cerebellar astrocytes. |
2005-06-24 |
2023-08-12 |
mouse |
| Lan Zhu, Piergiorgio Strata, Pavle R Andju. Pharmacology of the metabotropic glutamate receptor mediated current at the climbing fiber to Purkinje cell synapse. Progress in brain research. vol 148. 2005-05-24. PMID:15661198. |
using whole cell patch-clamp recording from pcs in rat cerebellar slices with ampa receptors blocked and glutamate uptake impaired we demonstrate a more complex pharmacology of a current obtained by single or train cf stimulation. |
2005-05-24 |
2023-08-12 |
rat |
| Yueh-Jan Wang, Guo-Fang Tsen. Spinal axonal injury induces brief downregulation of ionotropic glutamate receptors and no stripping of synapses in cord-projection central neurons. Journal of neurotrauma. vol 21. issue 11. 2005-04-28. PMID:15684654. |
since cerebellar fibers are glutamatergic, we examined the expression of ionotropic receptor subunits glur1-4 and nr1 for ampa and nmda receptors, respectively, in control and injured neurons using immunolabeling methods. |
2005-04-28 |
2023-08-12 |
human |
| K Banaudha, A M Marin. AMPA prevents glutamate-induced neurotoxicity and apoptosis in cultured cerebellar granule cell neurons. Neurotoxicity research. vol 2. issue 1. 2005-04-04. PMID:15545006. |
exposure of cultured cerebellar neurons to alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) in the presence of aniracetam protects all of the vulnerable neurons against the excitotoxic actions of glutamate acting on n-methyl-d-aspartate receptors. |
2005-04-04 |
2023-08-12 |
Not clear |
| K Banaudha, A M Marin. AMPA prevents glutamate-induced neurotoxicity and apoptosis in cultured cerebellar granule cell neurons. Neurotoxicity research. vol 2. issue 1. 2005-04-04. PMID:15545006. |
pretreatment of cerebellar neurons with the ampa antagonist, 6-cyano-7-nitroquinoxaline-2,3-dione blocked the neuroprotective effect mediated by ampa indicating that the neuroprotective effect is mediated specifically by ampa receptors. |
2005-04-04 |
2023-08-12 |
Not clear |
| Maya Yamazaki, Takako Ohno-Shosaku, Masahiro Fukaya, Masanobu Kano, Masahiko Watanabe, Kenji Sakimur. A novel action of stargazin as an enhancer of AMPA receptor activity. Neuroscience research. vol 50. issue 4. 2005-03-15. PMID:15567474. |
the striking defect in the stg cerebellum is the lack of functional ampa receptors on granule cells. |
2005-03-15 |
2023-08-12 |
mouse |
| Jordan P Steinberg, Richard L Huganir, David J Linde. N-ethylmaleimide-sensitive factor is required for the synaptic incorporation and removal of AMPA receptors during cerebellar long-term depression. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 52. 2005-02-28. PMID:15608060. |
n-ethylmaleimide-sensitive factor is required for the synaptic incorporation and removal of ampa receptors during cerebellar long-term depression. |
2005-02-28 |
2023-08-12 |
mouse |
| Jordan P Steinberg, Richard L Huganir, David J Linde. N-ethylmaleimide-sensitive factor is required for the synaptic incorporation and removal of AMPA receptors during cerebellar long-term depression. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 52. 2005-02-28. PMID:15608060. |
cerebellar long-term depression (ltd) is a persistent attenuation of synaptic transmission at the parallel fiber-purkinje cell synapse mediated by the removal of glur2 subunit-containing alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptors. |
2005-02-28 |
2023-08-12 |
mouse |
| Jordan P Steinberg, Richard L Huganir, David J Linde. N-ethylmaleimide-sensitive factor is required for the synaptic incorporation and removal of AMPA receptors during cerebellar long-term depression. Proceedings of the National Academy of Sciences of the United States of America. vol 101. issue 52. 2005-02-28. PMID:15608060. |
these findings demonstrate that interaction of ampa receptors with n-ethylmaleimide-sensitive factor plays a critical role in incorporation of ampa receptors into synapses and for their subsequent removal during cerebellar ltd. |
2005-02-28 |
2023-08-12 |
mouse |
| Wim Vandenberghe, Roger A Nicoll, David S Bred. Stargazin is an AMPA receptor auxiliary subunit. Proceedings of the National Academy of Sciences of the United States of America. vol 102. issue 2. 2005-02-25. PMID:15630087. |
here, we use blue native gel electrophoresis to analyze the composition of native ampa receptor complexes in cerebellar extracts. |
2005-02-25 |
2023-08-12 |
Not clear |
| Josette S Lindahl, Joyce Keife. Glutamate receptor subunits are altered in forebrain and cerebellum in rats chronically exposed to the NMDA receptor antagonist phencyclidine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 11. 2005-01-11. PMID:15138442. |
in this study, we examined the relative distribution of the nmda receptor subunits, as well as the subunits of its modulating receptor, alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (ampa) in the forebrain, hippocampus, and cerebellum of rats chronically exposed to pcp. |
2005-01-11 |
2023-08-12 |
rat |
| Jane H Ives, Susanna Fung, Priyanka Tiwari, Helen L Payne, Christopher L Thompso. Microtubule-associated protein light chain 2 is a stargazin-AMPA receptor complex-interacting protein in vivo. The Journal of biological chemistry. vol 279. issue 30. 2004-09-21. PMID:15136571. |
immunoprecipitations of triton x-100 soluble cerebellar extracts revealed that lc2 is pulled down not only by anti-stargazin antibodies but also anti-glur2 antibodies suggesting that stargazin and ampa receptor subunits associate with lc2. |
2004-09-21 |
2023-08-12 |
mouse |
| Jane H Ives, Susanna Fung, Priyanka Tiwari, Helen L Payne, Christopher L Thompso. Microtubule-associated protein light chain 2 is a stargazin-AMPA receptor complex-interacting protein in vivo. The Journal of biological chemistry. vol 279. issue 30. 2004-09-21. PMID:15136571. |
since this complex was extracted using triton x-100 and was devoid of psd95, sap97, and actin we postulate that lc2 is involved in trafficking of ampa receptors in cerebellar neurons before they are anchored at the synapse. |
2004-09-21 |
2023-08-12 |
mouse |
| Isabel Suárez, Guillermo Bodega, Javier Fernández-Ruiz, José Antonio Ramos, Miguel Rubio, Benjamín Fernánde. Down-regulation of the AMPA glutamate receptor subunits GluR1 and GluR2/3 in the rat cerebellum following pre- and perinatal delta9-tetrahydrocannabinol exposure. Cerebellum (London, England). vol 3. issue 2. 2004-08-23. PMID:15233572. |
down-regulation of the ampa glutamate receptor subunits glur1 and glur2/3 in the rat cerebellum following pre- and perinatal delta9-tetrahydrocannabinol exposure. |
2004-08-23 |
2023-08-12 |
rat |
| Isabel Suárez, Guillermo Bodega, Javier Fernández-Ruiz, José Antonio Ramos, Miguel Rubio, Benjamín Fernánde. Down-regulation of the AMPA glutamate receptor subunits GluR1 and GluR2/3 in the rat cerebellum following pre- and perinatal delta9-tetrahydrocannabinol exposure. Cerebellum (London, England). vol 3. issue 2. 2004-08-23. PMID:15233572. |
this paper reports the effects of pre- and perinatal exposure to delta9-tetrahydrocannabinol (thc) on expression levels of specific ampa glutamate receptor subunits (glur1 and glur2/3) in the cerebellum of male and female rats. |
2004-08-23 |
2023-08-12 |
rat |
| Isabel Suárez, Guillermo Bodega, Javier Fernández-Ruiz, José Antonio Ramos, Miguel Rubio, Benjamín Fernánde. Down-regulation of the AMPA glutamate receptor subunits GluR1 and GluR2/3 in the rat cerebellum following pre- and perinatal delta9-tetrahydrocannabinol exposure. Cerebellum (London, England). vol 3. issue 2. 2004-08-23. PMID:15233572. |
these changes in ampa receptor subunit levels may correlate with the decreased excitatory neurotransmission described in the cerebellum after cannabinoid treatment, which could play a significant role in the biochemical effects of thc. |
2004-08-23 |
2023-08-12 |
rat |