| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jonathan L C Lee, Felippe E Amorim, Lindsey F Cassini, Olavo B Amara. Different temporal windows for CB1 receptor involvement in contextual fear memory destabilisation in the amygdala and hippocampus. PloS one. vol 14. issue 1. 2019-09-27. PMID:30645588. |
different molecular mechanisms have been postulated for destabilisation in the amygdala and hippocampus, including cb1 receptor activation, protein degradation and ampa receptor exchange; however, most of the amygdala studies have used pre-reexposure interventions, while those in the hippocampus have usually performed them after reexposure. |
2019-09-27 |
2023-08-13 |
rat |
| Yanning Li, Runtao Ding, Xinghua Ren, Gehua Wen, Zhibin Dong, Hui Yao, Yaqing Tan, Hao Yu, Xiaolong Wang, Xiaoni Zhan, Jun Yao, Yan Lu, Guohua Zhang, Xu W. Long-term ketamine administration causes Tau protein phosphorylation and Tau protein-dependent AMPA receptor reduction in the hippocampus of mice. Toxicology letters. vol 315. 2019-09-23. PMID:31470060. |
long-term ketamine administration causes tau protein phosphorylation and tau protein-dependent ampa receptor reduction in the hippocampus of mice. |
2019-09-23 |
2023-08-13 |
mouse |
| Yanning Li, Runtao Ding, Xinghua Ren, Gehua Wen, Zhibin Dong, Hui Yao, Yaqing Tan, Hao Yu, Xiaolong Wang, Xiaoni Zhan, Jun Yao, Yan Lu, Guohua Zhang, Xu W. Long-term ketamine administration causes Tau protein phosphorylation and Tau protein-dependent AMPA receptor reduction in the hippocampus of mice. Toxicology letters. vol 315. 2019-09-23. PMID:31470060. |
most importantly, long-term ketamine administration decreased ampa receptor levels in the hippocampal cell membrane in a tau protein-dependent manner. |
2019-09-23 |
2023-08-13 |
mouse |
| Justin Stafford, Milene L Brownlow, Anthony Qualley, Ryan Jankor. AMPA receptor translocation and phosphorylation are induced by transcranial direct current stimulation in rats. Neurobiology of learning and memory. vol 150. 2019-09-16. PMID:29137960. |
our findings show that a single application of in vivo tdcs can affect both the translocation and phosphorylation of ampa receptors in the hippocampus while increasing ampa receptor phosphorylation in the hypothalamus. |
2019-09-16 |
2023-08-13 |
human |
| Justin Stafford, Milene L Brownlow, Anthony Qualley, Ryan Jankor. AMPA receptor translocation and phosphorylation are induced by transcranial direct current stimulation in rats. Neurobiology of learning and memory. vol 150. 2019-09-16. PMID:29137960. |
in the hippocampus, tdcs increased ampa translocation to the synapse and increased the phosphorylation of the s831 site on glua1. |
2019-09-16 |
2023-08-13 |
human |
| Karen Krukowski, Katherine Grue, Elma S Frias, John Pietrykowski, Tamako Jones, Gregory Nelson, Susanna Ros. Female mice are protected from space radiation-induced maladaptive responses. Brain, behavior, and immunity. vol 74. 2019-09-10. PMID:30107198. |
furthermore, we measured reductions in ampa expressing synaptic terminals in the hippocampus. |
2019-09-10 |
2023-08-13 |
mouse |
| Lucas Taoro-Gonzalez, Yaiza M Arenas, Andrea Cabrera-Pastor, Vicente Felip. Extracellular cGMP Reverses Altered Membrane Expression of AMPA Receptors in Hippocampus of Hyperammonemic Rats: Underlying Mechanisms. Molecular neurobiology. vol 56. issue 6. 2019-08-29. PMID:30328550. |
extracellular cgmp reverses altered membrane expression of ampa receptors in hippocampus of hyperammonemic rats: underlying mechanisms. |
2019-08-29 |
2023-08-13 |
rat |
| Lucas Taoro-Gonzalez, Yaiza M Arenas, Andrea Cabrera-Pastor, Vicente Felip. Extracellular cGMP Reverses Altered Membrane Expression of AMPA Receptors in Hippocampus of Hyperammonemic Rats: Underlying Mechanisms. Molecular neurobiology. vol 56. issue 6. 2019-08-29. PMID:30328550. |
chronic hyperammonemia impairs spatial memory by altering membrane expression of glua1 and glua2 subunits of ampa receptors in hippocampus. |
2019-08-29 |
2023-08-13 |
rat |
| Holger Haselmann, Francesco Mannara, Christian Werner, Jesús Planagumà, Federico Miguez-Cabello, Lars Schmidl, Benedikt Grünewald, Mar Petit-Pedrol, Knut Kirmse, Joseph Classen, Fatih Demir, Nikolaj Klöcker, David Soto, Sören Doose, Josep Dalmau, Stefan Hallermann, Christian Gei. Human Autoantibodies against the AMPA Receptor Subunit GluA2 Induce Receptor Reorganization and Memory Dysfunction. Neuron. vol 100. issue 1. 2019-08-05. PMID:30146304. |
autoantibodies to ampa receptors have been identified in humans with autoimmune encephalitis and severe defects of hippocampal function. |
2019-08-05 |
2023-08-13 |
mouse |
| N Yao, O Skiteva, X Zhang, P Svenningsson, K Chergu. Ketamine and its metabolite (2R,6R)-hydroxynorketamine induce lasting alterations in glutamatergic synaptic plasticity in the mesolimbic circuit. Molecular psychiatry. vol 23. issue 10. 2019-07-31. PMID:29158578. |
modulation of ampa receptors (ampars) in the hippocampus and prefrontal cortex is suggested to mediate the antidepressant action of ketamine and of one of its metabolites (2r,6r)-hydroxynorketamine ((2r,6r)-hnk). |
2019-07-31 |
2023-08-13 |
mouse |
| Tianhai Wang, Hongge Zhu, Yanshen Hou, Weixin Gu, Haichuan Wu, Yiwen Luan, Cheng Xiao, Chunyi Zho. Galantamine reversed early postoperative cognitive deficit via alleviating inflammation and enhancing synaptic transmission in mouse hippocampus. European journal of pharmacology. vol 846. 2019-07-29. PMID:30586550. |
electrophysiological recordings from ca1 hippocampal neurons revealed that pocd mice exhibited impairment in ampa receptor-mediated evoked excitatory postsynaptic currents (eepscs) without alteration in the rectification property of ampa receptors. |
2019-07-29 |
2023-08-13 |
mouse |
| Tianhai Wang, Hongge Zhu, Yanshen Hou, Weixin Gu, Haichuan Wu, Yiwen Luan, Cheng Xiao, Chunyi Zho. Galantamine reversed early postoperative cognitive deficit via alleviating inflammation and enhancing synaptic transmission in mouse hippocampus. European journal of pharmacology. vol 846. 2019-07-29. PMID:30586550. |
additionally, galantamine potentiated ampa receptor-mediated eepscs in the hippocampus more prominent in surgery mice than in sham mice. |
2019-07-29 |
2023-08-13 |
mouse |
| Nor Aqilah Binti Mohd Yusuf Yeo, Sangu Muthuraju, Jia Hui Wong, Faruque Reza Mohammed, Mohd Harizal Senik, Jingli Zhang, Siti Rafidah Yusof, Hasnan Jaafar, Mohd Llham Adenan, Habsah Mohamad, Tengku Sifzizul Tengku Muhammad, Jafri Malin Abdulla. Hippocampal amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid GluA1 (AMPA GluA1) receptor subunit involves in learning and memory improvement following treatment with Centella asiatica extract in adolescent rats. Brain and behavior. vol 8. issue 9. 2019-07-19. PMID:30105867. |
hippocampal amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid glua1 (ampa glua1) receptor subunit involves in learning and memory improvement following treatment with centella asiatica extract in adolescent rats. |
2019-07-19 |
2023-08-13 |
rat |
| Bihua Bie, Jiang Wu, Joseph F Foss, Mohamed Nagui. Amyloid fibrils induce dysfunction of hippocampal glutamatergic silent synapses. Hippocampus. vol 28. issue 8. 2019-07-16. PMID:29704282. |
silent glutamatergic synapses lacking functional ampa (α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionate) receptors exist in several brain regions including the hippocampus. |
2019-07-16 |
2023-08-13 |
rat |
| Mar Petit-Pedrol, Josefine Sell, Jesús Planagumà, Francesco Mannara, Marija Radosevic, Holger Haselmann, Mihai Ceanga, Lidia Sabater, Marianna Spatola, David Soto, Xavier Gasull, Josep Dalmau, Christian Gei. LGI1 antibodies alter Kv1.1 and AMPA receptors changing synaptic excitability, plasticity and memory. Brain : a journal of neurology. vol 141. issue 11. 2019-07-15. PMID:30346486. |
confocal analysis of hippocampal slices of mice infused with pooled igg from eight patients, but not pooled igg from controls, showed a decrease of total and synaptic levels of kv1.1 and ampa receptors. |
2019-07-15 |
2023-08-13 |
mouse |
| Hiroshi Inami, Jun-Ichi Shishikura, Tomoyuki Yasunaga, Masaaki Hirano, Takenori Kimura, Hiroshi Yamashita, Kazushige Ohno, Shuichi Sakamot. Synthesis and Pharmacological Evaluation of 3-[(4-Oxo-4H-pyrido[3,2-e][1,3]thiazin-2-yl)(phenyl)amino]propanenitrile Derivatives as Orally Active AMPA Receptor Antagonists. Chemical & pharmaceutical bulletin. vol 67. issue 7. 2019-07-03. PMID:31257325. |
in our search for novel orally active α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor antagonists, we found that conversion of an allyl group in the lead compound 2-[allyl(4-methylphenyl)amino]-4h-pyrido[3,2-e][1,3]thiazin-4-one (4) to a 2-cyanoethyl group significantly increased inhibitory activity against ampa receptor-mediated kainate-induced toxicity in rat hippocampal cultures. |
2019-07-03 |
2023-08-13 |
mouse |
| Y M Geng, J T Xue, J P Su, H Y L. Molecular mechanism of action of valproate acid alone or in combination with chlorpromazine in the epigenetic regulation of schizophrenia. Journal of biological regulators and homeostatic agents. vol 32. issue 6. 2019-06-14. PMID:30574748. |
the real time pcr assay was used to detect the mrna expression changes of gaba system gene [gabbr1 (gaba b receptor 1)], gad1 (glutamic acid decarboxylase1), gad2 (glutamic acid decarboxylase2), lipase metabolic key enzyme lpl (lipoprotein lipase) gene, glutamate neurotransmitter gene gria2 (ampa subtype glutamate receptors 2), inward rectifier potassium channel members kcnj4 (potassium voltage-gated channel subfamily j member 4) and neuropeptide signal gene tac1 (tachykinin precursor 1,tac1) in four brain regions: the prefrontal cortex (pc), the amygdala (am), the caudate-putamen (cpu) and the hippocampus (hip). |
2019-06-14 |
2023-08-13 |
rat |
| Mariline M Silva, Beatriz Rodrigues, Joana Fernandes, Sandra D Santos, Laura Carreto, Manuel A S Santos, Paulo Pinheiro, Ana Luísa Carvalh. MicroRNA-186-5p controls GluA2 surface expression and synaptic scaling in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 12. 2019-05-31. PMID:30808806. |
here, we report that chronic blockade of glutamate receptors of the ampa and nmda types in hippocampal neurons in culture induces changes in the neuronal mrna and mirna transcriptomes, leading to synaptic upscaling. |
2019-05-31 |
2023-08-13 |
Not clear |
| Tsvetomira Atanasova, Zoya Kharybina, Tiina Kaarela, Johanna Huupponen, Natalia V Luchkina, Tomi Taira, Sari E Laur. GluA4 Dependent Plasticity Mechanisms Contribute to Developmental Synchronization of the CA3-CA1 Circuitry in the Hippocampus. Neurochemical research. vol 44. issue 3. 2019-05-07. PMID:28856535. |
at immature ca3-ca1 synapses in the hippocampus, pka-driven synaptic insertion of glua4 ampa receptors is the predominant mechanism for synaptic strengthening. |
2019-05-07 |
2023-08-13 |
Not clear |
| Akira Terashima, Young Ho Suh, John T R Isaa. The AMPA Receptor Subunit GluA1 is Required for CA1 Hippocampal Long-Term Potentiation but is not Essential for Synaptic Transmission. Neurochemical research. vol 44. issue 3. 2019-05-07. PMID:29098531. |
the ampa receptor subunit glua1 is required for ca1 hippocampal long-term potentiation but is not essential for synaptic transmission. |
2019-05-07 |
2023-08-13 |
mouse |