All Relations between \u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and hippocampus

Publication Sentence Publish Date Extraction Date Species
Mark William Lopes, Samantha Cristiane Lopes, Ana Paula Costa, Filipe Marques Gonçalves, Débora Kurrle Rieger, Tanara Vieira Peres, Helena Eyng, Rui Daniel Prediger, Alexandre Paim Diaz, Jean Costa Nunes, Roger Walz, Rodrigo Bainy Lea. Region-specific alterations of AMPA receptor phosphorylation and signaling pathways in the pilocarpine model of epilepsy. Neurochemistry international. vol 87. 2016-05-24. PMID:25983036. these findings suggest a differential imbalance of the signaling pathways involved in the site-specific phosphorylation of ampa receptor in the hippocampus. 2016-05-24 2023-08-13 rat
Pojeong Park, Thomas M Sanderson, Mascia Amici, Sun-Lim Choi, Zuner A Bortolotto, Min Zhuo, Bong-Kiun Kaang, Graham L Collingridg. Calcium-Permeable AMPA Receptors Mediate the Induction of the Protein Kinase A-Dependent Component of Long-Term Potentiation in the Hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 2. 2016-05-17. PMID:26758849. calcium-permeable ampa receptors mediate the induction of the protein kinase a-dependent component of long-term potentiation in the hippocampus. 2016-05-17 2023-08-13 rat
Maryam Ghafari, Soheil Keihan Falsafi, Harald Höger, Keiryn L Bennett, Gert Lube. Identification of new phosphorylation sites of AMPA receptors in the rat hippocampus--A resource for neuroscience research. Proteomics. Clinical applications. vol 9. issue 9-10. 2016-04-19. PMID:25656447. identification of new phosphorylation sites of ampa receptors in the rat hippocampus--a resource for neuroscience research. 2016-04-19 2023-08-13 rat
Surya P Pandey, Hemant K Singh, S Prasa. Alterations in Hippocampal Oxidative Stress, Expression of AMPA Receptor GluR2 Subunit and Associated Spatial Memory Loss by Bacopa monnieri Extract (CDRI-08) in Streptozotocin-Induced Diabetes Mellitus Type 2 Mice. PloS one. vol 10. issue 7. 2016-04-19. PMID:26161865. alterations in hippocampal oxidative stress, expression of ampa receptor glur2 subunit and associated spatial memory loss by bacopa monnieri extract (cdri-08) in streptozotocin-induced diabetes mellitus type 2 mice. 2016-04-19 2023-08-13 mouse
Surya P Pandey, Hemant K Singh, S Prasa. Alterations in Hippocampal Oxidative Stress, Expression of AMPA Receptor GluR2 Subunit and Associated Spatial Memory Loss by Bacopa monnieri Extract (CDRI-08) in Streptozotocin-Induced Diabetes Mellitus Type 2 Mice. PloS one. vol 10. issue 7. 2016-04-19. PMID:26161865. here, we demonstrate that dm2 mice treated orally with lower dose of cdri-08 (50- or 100 mg/kg bw) is able to significantly enhance spatial memory in stz-dm2 mice and this is correlated with a significant decline in oxidative stress and up regulation of the ampa receptor glur2 subunit gene expression in the hippocampus. 2016-04-19 2023-08-13 mouse
Xike Qin, Yongjun Jiang, Yiu Chung Tse, Yunling Wang, Tak Pan Wong, Hemant K Paude. Early Growth Response 1 (Egr-1) Regulates N-Methyl-d-aspartate Receptor (NMDAR)-dependent Transcription of PSD-95 and α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid Receptor (AMPAR) Trafficking in Hippocampal Primary Neurons. The Journal of biological chemistry. vol 290. issue 49. 2016-04-19. PMID:26475861. here, we show that the hippocampus of mice lacking egr-1 displays electrophysiology properties and ultrastructure that are similar to mice overexpressing psd-95, a major scaffolding protein of postsynaptic density involved in synapse formation, synaptic plasticity, and synaptic targeting of ampa receptors (ampars), which mediate the vast majority of excitatory transmission in the cns. 2016-04-19 2023-08-13 mouse
Nilmini Viswaprakash, Thirumalini Vaithianathan, Ajitan Viswaprakash, Robert Judd, Kodeeswaran Parameshwaran, Vishnu Suppiramania. Insulin treatment restores glutamate (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor function in the hippocampus of diabetic rats. Journal of neuroscience research. vol 93. issue 9. 2016-04-12. PMID:25807926. this study examines the functional properties of synaptic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptors and the expression of synaptic molecules that regulate glutamatergic synaptic transmission in the hippocampus of stz-diabetic rats. 2016-04-12 2023-08-13 rat
Nilmini Viswaprakash, Thirumalini Vaithianathan, Ajitan Viswaprakash, Robert Judd, Kodeeswaran Parameshwaran, Vishnu Suppiramania. Insulin treatment restores glutamate (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) receptor function in the hippocampus of diabetic rats. Journal of neuroscience research. vol 93. issue 9. 2016-04-12. PMID:25807926. these impairments in synaptic currents gated by ampa receptors were accompanied by decreased protein levels of ampa receptor subunit glur1, the presynaptic protein synaptophysin, and the postsynaptic anchor protein postsynaptic density protein 95 in the hippocampus of diabetic rats. 2016-04-12 2023-08-13 rat
Xia Jiang, Gao-Shang Chai, Zhi-Hao Wang, Yu Hu, Xiao-Guang Li, Zhi-Wei Ma, Qun Wang, Jian-Zhi Wang, Gong-Ping Li. Spatial training preserves associative memory capacity with augmentation of dendrite ramification and spine generation in Tg2576 mice. Scientific reports. vol 5. 2016-04-05. PMID:25820815. in the molecular level, the mwm training remarkably activated calcium/calmodulin-dependent protein kinase ii (camkii) with elevation of glutamate ampa receptor glua1 subunit (glua1), postsynaptic density protein 93 (psd93) and postsynaptic density protein 95 (psd95) in the hippocampus. 2016-04-05 2023-08-13 mouse
Hirobumi Tada, Mayu Koide, Wakana Ara, Yusuke Shibata, Toshiya Funabashi, Kumiko Suyama, Takahisa Goto, Takuya Takahash. Estrous Cycle-Dependent Phasic Changes in the Stoichiometry of Hippocampal Synaptic AMPA Receptors in Rats. PloS one. vol 10. issue 6. 2016-03-28. PMID:26121335. estrous cycle-dependent phasic changes in the stoichiometry of hippocampal synaptic ampa receptors in rats. 2016-03-28 2023-08-13 rat
Hirobumi Tada, Mayu Koide, Wakana Ara, Yusuke Shibata, Toshiya Funabashi, Kumiko Suyama, Takahisa Goto, Takuya Takahash. Estrous Cycle-Dependent Phasic Changes in the Stoichiometry of Hippocampal Synaptic AMPA Receptors in Rats. PloS one. vol 10. issue 6. 2016-03-28. PMID:26121335. here we show that in female rats, inhibitory-avoidance (ia) task (hippocampus-dependent contextual fear-learning task) drives glua2-lacking ca2+-permeable ampa receptors (cp-ampars) into the hippocampal ca3-ca1 synapses during all periods of the estrous cycle except the proestrous period, when estrogen levels are high. 2016-03-28 2023-08-13 rat
Quentin Chevy, Martin Heubl, Marie Goutierre, Stéphanie Backer, Imane Moutkine, Emmanuel Eugène, Evelyne Bloch-Gallego, Sabine Lévi, Jean Christophe Ponce. KCC2 Gates Activity-Driven AMPA Receptor Traffic through Cofilin Phosphorylation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 48. 2016-03-28. PMID:26631461. here we show that suppressing kcc2 expression in rat hippocampal neurons precludes long-term potentiation of glutamatergic synapses specifically by preventing activity-driven membrane delivery of ampa receptors. 2016-03-28 2023-08-13 rat
Norihito Oi, Masaki Tokunaga, Michiyuki Suzuki, Yuji Nagai, Yosuke Nakatani, Noboru Yamamoto, Jun Maeda, Takafumi Minamimoto, Ming-Rong Zhang, Tetsuya Suhara, Makoto Higuch. Development of Novel PET Probes for Central 2-Amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic Acid Receptors. Journal of medicinal chemistry. vol 58. issue 21. 2016-02-25. PMID:26469379. [(11)c]21a was shown by autoradiography to specifically bind to the neocortex and hippocampus, consistent with ampa receptor localization. 2016-02-25 2023-08-13 rat
Helene A Fachim, Adriana C Pereira, Melina M Iyomasa-Pilon, Maria L N M Ros. Differential Expression of AMPA Subunits Induced by NMDA Intrahippocampal Injection in Rats. Frontiers in neuroscience. vol 10. 2016-02-25. PMID:26912994. the aim of this work was to study the time course of changes in the expression of glur1 and glur2 subunits of glutamate amino-acid-3-hydroxy-5-methyl-isoxazol-4-propionic acid (ampa) receptors in rat hippocampus induced by nmda intrahippocampal injection. 2016-02-25 2023-08-13 rat
Scott D Gleason, Akihiko Kato, Hai H Bui, Linda K Thompson, Sabrina N Valli, Patrick V Stutz, Ming-Shang Kuo, Julie F Falcone, Wesley H Anderson, Xia Li, Jeffrey M Witki. Inquiries into the Biological Significance of Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8 Through Investigations of TARP γ-8 Null Mice§. CNS & neurological disorders drug targets. vol 14. issue 5. 2016-02-16. PMID:25921737. most strikingly, ampa receptors associated with this tarp have a relatively high localization in the hippocampus. 2016-02-16 2023-08-13 mouse
Elisabetta Gerace, Domenico E Pellegrini-Giampietro, Flavio Moroni, Guido Mannaion. Poly(ADP-Ribose)Polymerase 1 (PARP-1) Activation and Ca(2+) Permeable α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Channels in Post-Ischemic Brain Damage: New Therapeutic Opportunities? CNS & neurological disorders drug targets. vol 14. issue 5. 2016-02-16. PMID:25924998. biochemical and electrophysiological approaches showed that mnng exposure caused an increased expression and function of the calcium permeable α-amino- 3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) channels in the ca1 but not in the ca3 hippocampal region. 2016-02-16 2023-08-13 rat
Rut Fadó, David Soto, Alfredo J Miñano-Molina, Macarena Pozo, Patricia Carrasco, Natalia Yefimenko, José Rodríguez-Álvarez, Núria Casal. Novel Regulation of the Synthesis of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Subunit GluA1 by Carnitine Palmitoyltransferase 1C (CPT1C) in the Hippocampus. The Journal of biological chemistry. vol 290. issue 42. 2016-02-16. PMID:26338711. novel regulation of the synthesis of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor subunit glua1 by carnitine palmitoyltransferase 1c (cpt1c) in the hippocampus. 2016-02-16 2023-08-13 mouse
Jong Wan Kim, Gyoung Yim Ha, Yong Wook Jun. Chronic renal failure induces cell death in rat hippocampal CA1 via upregulation of αCaMKII/NR2A synaptic complex and phosphorylated GluR1-containing AMPA receptor cascades. Kidney research and clinical practice. vol 33. issue 3. 2016-02-15. PMID:26877964. the aim of present study was to investigate the alterations of nmda and ampa receptors responsible for hippocampal synaptic dysfunction and selective neuronal cell death after chronic renal failure (crf) which may be associated with impairment of working memory. 2016-02-15 2023-08-13 rat
Jing Chen, Li-Hua Peng, Jie Luo, Li Liu, Feng Lv, Ping Li, Li Ao, Xue-Chao Hao, Su Mi. Effects of low-dose ketamine combined with propofol on phosphorylation of AMPA receptor GluR1 subunit and GABAA receptor in hippocampus of stressed rats receiving electroconvulsive shock. The journal of ECT. vol 31. issue 1. 2016-02-11. PMID:24831997. effects of low-dose ketamine combined with propofol on phosphorylation of ampa receptor glur1 subunit and gabaa receptor in hippocampus of stressed rats receiving electroconvulsive shock. 2016-02-11 2023-08-13 rat
Bharanidharan Shanmugasundaram, Ajinkya Sase, András G Miklosi, Fernando J Sialana, Saraswathi Subramaniyan, Yogesh D Aher, Marion Gröger, Harald Höger, Keiryn L Bennett, Gert Lube. Frontal cortex and hippocampus neurotransmitter receptor complex level parallels spatial memory performance in the radial arm maze. Behavioural brain research. vol 289. 2016-02-05. PMID:25930220. frontal cortical levels of rcs containing ampa receptors glua1, glua2, nmda receptors glun1 and glun2a, dopamine receptor d1, acetylcholine nicotinic receptor alpha 7 (nachr-α7) and hippocampal levels of rcs containing d1, glun1, glun2b and nachr-α7 were increased in the trained group; phosphorylated dopamine transporter levels were decreased in the trained group. 2016-02-05 2023-08-13 rat