All Relations between \u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and hippocampus

Publication Sentence Publish Date Extraction Date Species
Tatyana Y Postnikova, Alexandra V Griflyuk, Arseniy S Zhigulin, Elena B Soboleva, Oleg I Barygin, Dmitry V Amakhin, Aleksey V Zaitse. Febrile Seizures Cause a Rapid Depletion of Calcium-Permeable AMPA Receptors at the Synapses of Principal Neurons in the Entorhinal Cortex and Hippocampus of the Rat. International journal of molecular sciences. vol 24. issue 16. 2023-08-26. PMID:37628802. febrile seizures cause a rapid depletion of calcium-permeable ampa receptors at the synapses of principal neurons in the entorhinal cortex and hippocampus of the rat. 2023-08-26 2023-09-07 rat
Duk-Shin Lee, Tae-Hyun Kim, Hana Park, Ji-Eun Ki. PDI augments kainic acid-induced seizure activity and neuronal death by inhibiting PP2A-GluA2-PICK1-mediated AMPA receptor internalization in the mouse hippocampus. Scientific reports. vol 13. issue 1. 2023-08-25. PMID:37626185. pdi augments kainic acid-induced seizure activity and neuronal death by inhibiting pp2a-glua2-pick1-mediated ampa receptor internalization in the mouse hippocampus. 2023-08-25 2023-09-07 mouse
Lei Chen, Qiang Fu, Yang Du, Zhong-Yong Jiang, Yong Chen. Transcriptome Analysis and Epigenetics Regulation in the Hippocampus and the Prefrontal Cortex of VPA-Induced Rat Model. Molecular neurobiology. 2023-08-17. PMID:37592184. further, the predicted and validated target mrna of de mirna enriched pathways involved neurotransmitter uptake, long-term synaptic depression, and ampa receptor complex (anti-glua2-b) in the hippocampus; as well as the neuroactive ligand-receptor interaction and regulation of postsynaptic membrane potential in the prefrontal cortex. 2023-08-17 2023-09-07 rat
Elisabetta Gerace, Lorenzo Curti, Lucia Caffino, Elisabetta Bigagli, Francesca Mottarlini, Fernando Castillo Díaz, Alice Ilari, Cristina Luceri, Carlo Dani, Fabio Fumagalli, Alessio Masi, Guido Mannaion. Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices. European journal of pharmacology. 2023-07-11. PMID:37433363. ethanol-induced ampa alterations are mediated by mglu5 receptors through mirna upregulation in hippocampal slices. 2023-07-11 2023-08-14 Not clear
Elisabetta Gerace, Lorenzo Curti, Lucia Caffino, Elisabetta Bigagli, Francesca Mottarlini, Fernando Castillo Díaz, Alice Ilari, Cristina Luceri, Carlo Dani, Fabio Fumagalli, Alessio Masi, Guido Mannaion. Ethanol-induced AMPA alterations are mediated by mGLU5 receptors through miRNA upregulation in hippocampal slices. European journal of pharmacology. 2023-07-11. PMID:37433363. we have recently demonstrated that chronic etoh exposure, followed by withdrawal, induces a significant decrease in ampa receptor (ampar) expression and function in developing hippocampus in vitro. 2023-07-11 2023-08-14 Not clear
Ana Belén Sanz-Martos, Esmeralda Fuentes-Verdugo, Beatriz Merino, Lidia Morales, Vicente Pérez, Roberto Capellán, Ricardo Pellón, Miguel Miguéns, Nuria Del Olm. SCHEDULE-INDUCED ALCOHOL INTAKE DURING ADOLESCENCE SEX DEPENDENTLY IMPAIRS HIPPOCAMPAL SYNAPTIC PLASTICITY AND SPATIAL MEMORY. Behavioural brain research. 2023-07-09. PMID:37423317. in contrast, alcohol did not modify hippocampal gene expression of ampa and nmda glutamate receptor subunits, although there are differences in the expression levels of several genes relevant to synaptic plasticity mechanisms underlying learning and memory processes, related to alcohol consumption as ephb2, sex differences as pi3k or the interaction of both factors such as pten. 2023-07-09 2023-08-14 rat
Chengzhang Li, Zhenrong Li, Sihan Xu, Sanwei Jiang, Zhenli Ye, Bin Yu, Shixiang Gong, Junmei Li, Qilin Hu, Bingyan Feng, Mengmeng Wang, Chengbiao L. Exogenous AMPA downregulates gamma-frequency network oscillation in CA3 of rat hippocampal slices. Scientific reports. vol 13. issue 1. 2023-06-29. PMID:37386056. exogenous ampa downregulates gamma-frequency network oscillation in ca3 of rat hippocampal slices. 2023-06-29 2023-08-14 rat
Chengzhang Li, Zhenrong Li, Sihan Xu, Sanwei Jiang, Zhenli Ye, Bin Yu, Shixiang Gong, Junmei Li, Qilin Hu, Bingyan Feng, Mengmeng Wang, Chengbiao L. Exogenous AMPA downregulates gamma-frequency network oscillation in CA3 of rat hippocampal slices. Scientific reports. vol 13. issue 1. 2023-06-29. PMID:37386056. however, we demonstrated that exogenous ampa dose-dependently inhibited carbachol (cch)-induced γ oscillation in the ca3 area of rat hippocampal slices, but the underlying mechanism is not clear. 2023-06-29 2023-08-14 rat
Vaskar Das, Michael B Basovich, Craig J Thomas, Jeffrey S Kroin, Asokumar Buvanendran, Robert J McCarth. A Pharmacological Evaluation of the Analgesic Effect and Hippocampal Protein Modulation of the Ketamine Metabolite (2R,6R)-Hydroxynorketamine in Murine Pain Models. Anesthesia and analgesia. 2023-06-15. PMID:37319016. the purpose of this study was to evaluate the α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (ampa) dependence of (2r,6r)-hnk analgesia and protein changes in the hippocampus in murine pain models administered (2r,6r)-hnk or saline. 2023-06-15 2023-08-14 Not clear
Guillermo Iborra-Lázaro, Souhail Djebari, Irene Sánchez-Rodríguez, Esther Gratacòs-Batlle, Nuria Sánchez-Fernández, Marija Radošević, Núria Casals, Juan de Dios Navarro-López, David Soto Del Cerro, Lydia Jiménez-Día. CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative, and non-associative learning. The Journal of physiology. 2023-06-13. PMID:37309891. its deficiency has been recently shown to disrupt dendritic spine maturation and ampa receptor synthesis and trafficking in the hippocampus, but its contribution to synaptic plasticity and cognitive learning and memory processes remains mostly unknown. 2023-06-13 2023-08-14 mouse
Guillermo Iborra-Lázaro, Souhail Djebari, Irene Sánchez-Rodríguez, Esther Gratacòs-Batlle, Nuria Sánchez-Fernández, Marija Radošević, Núria Casals, Juan de Dios Navarro-López, David Soto Del Cerro, Lydia Jiménez-Día. CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative, and non-associative learning. The Journal of physiology. 2023-06-13. PMID:37309891. key points: cpt1c, a neuron-specific interactor protein involved in ampa receptors synthesis and trafficking, was found highly expressed in the hippocampus, amygdala and various motor regions. 2023-06-13 2023-08-14 mouse
Guillermo Iborra-Lázaro, Souhail Djebari, Irene Sánchez-Rodríguez, Esther Gratacòs-Batlle, Nuria Sánchez-Fernández, Marija Radošević, Núria Casals, Juan de Dios Navarro-López, David Soto Del Cerro, Lydia Jiménez-Día. CPT1C is required for synaptic plasticity and oscillatory activity that supports motor, associative, and non-associative learning. The Journal of physiology. 2023-06-13. PMID:37309891. abstract figure legend cpt1c regulates the trafficking of ampa receptors (ampars) containing the glua1 subunit to the membrane surface and the maturation of dendritic spines in the hippocampus. 2023-06-13 2023-08-14 mouse
Ga-Young Choi, Hyun-Bum Kim, Jae-Min Cho, Inturu Sreelatha, In-Seo Lee, Hee-Seok Kweon, Sehyun Sul, Sun Ae Kim, Sungho Maeng, Ji-Ho Par. Umbelliferone Ameliorates Memory Impairment and Enhances Hippocampal Synaptic Plasticity in Scopolamine-Induced Rat Model. Nutrients. vol 15. issue 10. 2023-05-27. PMID:37242234. a hippocampal tissue analysis revealed that umb attenuated a scop-induced blockade of field excitatory post-synaptic potential (fepsp) activity and ameliorated the impairment of ltp by the nmda and ampa receptor antagonists. 2023-05-27 2023-08-14 rat
Mengjia Huang, Na-Ryum Bin, Jayant Rai, Ke Ma, Chun Hin Chow, Sarah Eide, Hidekiyo Harada, Jianbing Xiao, Daorong Feng, Hong-Shuo Sun, Zhong-Ping Feng, Herbert Y Gaisano, Jeffrey E Pessin, Philippe P Monnier, Kenichi Okamoto, Liang Zhang, Shuzo Sugit. Neuronal SNAP-23 is critical for synaptic plasticity and spatial memory independently of NMDA receptor regulation. iScience. vol 26. issue 5. 2023-05-11. PMID:37168570. electrophysiological analysis of snap-23 deficient neurons using acute hippocampal slices showed normal basal neurotransmission in ca3-ca1 synapses with unchanged ampa and nmda currents. 2023-05-11 2023-08-14 mouse
Chenxu Wang, Yan Zhou, Keliang Xie, Yuan Yuan, Guolin Wang, Yonghao Y. [Regulation of AMPA receptor on propofol induced hippocampal mitochondrial injury in neonatal rats]. Zhonghua wei zhong bing ji jiu yi xue. vol 35. issue 2. 2023-03-14. PMID:36916380. [regulation of ampa receptor on propofol induced hippocampal mitochondrial injury in neonatal rats]. 2023-03-14 2023-08-14 rat
Chenxu Wang, Yan Zhou, Keliang Xie, Yuan Yuan, Guolin Wang, Yonghao Y. [Regulation of AMPA receptor on propofol induced hippocampal mitochondrial injury in neonatal rats]. Zhonghua wei zhong bing ji jiu yi xue. vol 35. issue 2. 2023-03-14. PMID:36916380. to investigate whether propofol can cause injury to hippocampal mitochondria in neonatal rats and the regulation of excitatory amino acid receptor ampa receptor. 2023-03-14 2023-08-14 rat
Yu-Fen Lin, Ching-An Chen, Fang-Yu Hsu, Ya-Hsin Hsia. Elevated Hippocampal CRMP5 Mediates Chronic Stress-Induced Cognitive Deficits by Disrupting Synaptic Plasticity, Hindering AMPAR Trafficking, and Triggering Cytokine Release. International journal of molecular sciences. vol 24. issue 5. 2023-03-11. PMID:36902337. mechanistically, hippocampal crmp5 suppression by regulating glucocorticoid receptor phosphorylation alleviates chronic stress-induced synaptic atrophy, disruption of ampa receptor trafficking, and cytokine storms. 2023-03-11 2023-08-14 mouse
Li Luo, Le Yang, Kun Zhang, Shi-Meng Zhou, Yan Wang, Liu-Kun Yang, Bin Feng, Shui-Bing Liu, Yu-Mei Wu, Ming-Gao Zhao, Qi Yan. Caveolin-1-Mediated Cholesterol Accumulation Contributes to Exaggerated mGluR-Dependent Long-Term Depression and Impaired Cognition in Fmr1 Knockout Mice. Molecular neurobiology. 2023-03-01. PMID:36854997. moreover, hippocampal cav1 expression in fmr1 ko mice induced excessive endocytosis of the α-amino-3-hydroxyl-5-methyl-4-isoxazolepropionate (ampa) receptor subunit glua2. 2023-03-01 2023-08-14 mouse
Tomohiko Maruo, Kiyohito Mizutani, Muneaki Miyata, Toshihiko Kuriu, Shotaro Sakakibara, Hatena Takahashi, Daichi Kida, Kouki Maesaka, Tsukiko Sugaya, Ayuko Sakane, Takuya Sasaki, Yoshimi Takai, Kenji Manda. s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons. The Journal of biological chemistry. 2023-02-21. PMID:36803960. s-afadin binds to maguin/cnksr2 and regulates the localization of the ampa receptor and glutamatergic synaptic response in hippocampal neurons. 2023-02-21 2023-08-14 Not clear
Tomohiko Maruo, Kiyohito Mizutani, Muneaki Miyata, Toshihiko Kuriu, Shotaro Sakakibara, Hatena Takahashi, Daichi Kida, Kouki Maesaka, Tsukiko Sugaya, Ayuko Sakane, Takuya Sasaki, Yoshimi Takai, Kenji Manda. s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons. The Journal of biological chemistry. 2023-02-21. PMID:36803960. genetic ablation of maguin impaired psd-95 localization and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic (ampa) receptor surface accumulation in cultured hippocampal neurons. 2023-02-21 2023-08-14 Not clear