All Relations between \u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and hippocampus

Publication Sentence Publish Date Extraction Date Species
Meng-Hsuan Han, Song Jiao, Jie-Min Jia, Yong Chen, Cai Yun Chen, Marjan Gucek, Sanford P Markey, Zheng L. The novel caspase-3 substrate Gap43 is involved in AMPA receptor endocytosis and long-term depression. Molecular & cellular proteomics : MCP. vol 12. issue 12. 2014-07-31. PMID:24023391. moreover, in hippocampal neurons, gap43 mutants deficient in caspase-3 cleavage inhibit ampa receptor endocytosis and ltd. we further demonstrated that gap43, a protein well-known for its functions in axons, is also localized at postsynaptic sites. 2014-07-31 2023-08-12 Not clear
Adam J Granger, Roger A Nicol. LTD expression is independent of glutamate receptor subtype. Frontiers in synaptic neuroscience. vol 6. 2014-07-29. PMID:25071549. however, it is unclear if either glua1 or glua2 are absolutely required for ltd. we tested this hypothesis using constitutive knock-outs and single-cell molecular replacement of ampa receptor subunits in mouse hippocampus. 2014-07-29 2023-08-13 mouse
b' Max Nordgren, Tobias Karlsson, Maria Svensson, Josefin Koczy, Anna Josephson, Lars Olson, Anders Tingstr\\xc3\\xb6m, Stefan Bren\\xc3\\xa. Orchestrated regulation of Nogo receptors, LOTUS, AMPA receptors and BDNF in an ECT model suggests opening and closure of a window of synaptic plasticity. PloS one. vol 8. issue 11. 2014-07-22. PMID:24244357.' here we followed regulation of ngr1, ngr3, lotus, bdnf, and ampa subunits glur1 and glur2 flip and flop mrna levels in hippocampus at 2, 4, 12, 24, and 72 hours after a single episode of induced electroconvulsive seizures (ecs) in rats. 2014-07-22 2023-08-12 rat
Florian Freudenberg, Verena Marx, Peter H Seeburg, Rolf Sprengel, Tansu Celike. Circuit mechanisms of GluA1-dependent spatial working memory. Hippocampus. vol 23. issue 12. 2014-07-09. PMID:23929622. in this study, by targeted expression of glua1 containing ampa receptors in the forebrain of gria1(-/-) mice or by removing glua1 selectively from hippocampus of mice with "floxed" glua1 alleles (gria1(fl/fl) ), we show that swm requires glua1 action in cortical circuits but is only partially dependent on glua1-containing ampa receptors in hippocampus. 2014-07-09 2023-08-12 mouse
Florian Freudenberg, Verena Marx, Peter H Seeburg, Rolf Sprengel, Tansu Celike. Circuit mechanisms of GluA1-dependent spatial working memory. Hippocampus. vol 23. issue 12. 2014-07-09. PMID:23929622. these findings provide a novel insight into the neural circuits required for swm processing and argue that ampa mediated signaling across forebrain and hippocampus differentially contribute to encoding of swm. 2014-07-09 2023-08-12 mouse
Gordon B Feld, Tanja Lange, Steffen Gais, Jan Bor. Sleep-dependent declarative memory consolidation--unaffected after blocking NMDA or AMPA receptors but enhanced by NMDA coagonist D-cycloserine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 13. 2014-07-01. PMID:23887151. we speculate that glutamatergic activation during sleep is not only involved in consolidation but also in forgetting of hippocampal memory with both processes being differentially sensitive to dcs and unselective blockade of nmda and ampa receptors. 2014-07-01 2023-08-12 human
Luli Akinfiresoye, Yousef Tizab. Antidepressant effects of AMPA and ketamine combination: role of hippocampal BDNF, synapsin, and mTOR. Psychopharmacology. vol 230. issue 2. 2014-06-23. PMID:23732839. antidepressant effects of ampa and ketamine combination: role of hippocampal bdnf, synapsin, and mtor. 2014-06-23 2023-08-12 Not clear
Kevin Allen, Mariana Gil, Evgeny Resnik, Oana Toader, Peter Seeburg, Hannah Monye. Impaired path integration and grid cell spatial periodicity in mice lacking GluA1-containing AMPA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 18. 2014-06-23. PMID:24790195. mice lacking glua1-containing ampa receptors (glua1(-/-) mice) were previously shown to exhibit impaired hippocampal place cell selectivity. 2014-06-23 2023-08-13 mouse
Shinji Matsuda, Wataru Kakegawa, Timotheus Budisantoso, Toshihiro Nomura, Kazuhisa Kohda, Michisuke Yuzak. Stargazin regulates AMPA receptor trafficking through adaptor protein complexes during long-term depression. Nature communications. vol 4. 2014-06-19. PMID:24217640. here we show that stargazin, a transmembrane ampa receptor regulatory protein, forms a ternary complex with adaptor proteins ap-2 and ap-3a in hippocampal neurons, depending on its phosphorylation state. 2014-06-19 2023-08-12 Not clear
Graham L Collingridge, Stephane Peinea. Strippers reveal their depressing secrets: removing AMPA receptors. Neuron. vol 82. issue 1. 2014-06-02. PMID:24698263. (2014) describe a novel form of long-term depression of ampa receptor-mediated synaptic transmission in the hippocampus involving the activation of microglia. 2014-06-02 2023-08-13 Not clear
Xulong Wang, Giordano Lippi, David M Carlson, Darwin K Ber. Activation of α7-containing nicotinic receptors on astrocytes triggers AMPA receptor recruitment to glutamatergic synapses. Journal of neurochemistry. vol 127. issue 5. 2014-05-12. PMID:24032433. we show here that stimulation of α7-nachrs on astrocytes releases components that induce hippocampal neurons to acquire more α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptors post-synaptically at glutamatergic synapses. 2014-05-12 2023-08-12 Not clear
Yue Wang, Mark P Mattso. L-type Ca2+ currents at CA1 synapses, but not CA3 or dentate granule neuron synapses, are increased in 3xTgAD mice in an age-dependent manner. Neurobiology of aging. vol 35. issue 1. 2014-04-23. PMID:23932880. to elucidate potential biophysical alterations underlying aberrant neuronal network activity in ad, we performed whole-cell patch clamp analyses of l-type (nifedipine-sensitive) ca(2+) currents (l-vgcc), 4-aminopyridine-sensitive k(+) currents, and ampa (2-amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic acid) and nmda (n-methyl-d-aspartate) currents in ca1, ca3, and dentate granule neurons in hippocampal slices from young, middle-age, and old 3xtgad mice and age-matched wild type mice. 2014-04-23 2023-08-12 mouse
Elena Blanco-Suarez, Jonathan G Hanle. Distinct subunit-specific α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking mechanisms in cultured cortical and hippocampal neurons in response to oxygen and glucose deprivation. The Journal of biological chemistry. vol 289. issue 8. 2014-04-22. PMID:24403083. distinct subunit-specific α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor trafficking mechanisms in cultured cortical and hippocampal neurons in response to oxygen and glucose deprivation. 2014-04-22 2023-08-12 Not clear
Elena Blanco-Suarez, Jonathan G Hanle. Distinct subunit-specific α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor trafficking mechanisms in cultured cortical and hippocampal neurons in response to oxygen and glucose deprivation. The Journal of biological chemistry. vol 289. issue 8. 2014-04-22. PMID:24403083. cultured hippocampal neurons respond to ogd with a rapid internalization of ampa receptor (ampar) subunit glua2, resulting in a switch from glua2-containing ca(2+)-impermeable receptors to glua2-lacking ca(2+)-permeable subtypes (cp-ampars). 2014-04-22 2023-08-12 Not clear
Montree Maneepark, Anan Srikiatkhachorn, Saknan Bongsebandhu-phubhakd. Involvement of AMPA receptors in CSD-induced impairment of LTP in the hippocampus. Headache. vol 52. issue 10. 2014-04-14. PMID:22862296. involvement of ampa receptors in csd-induced impairment of ltp in the hippocampus. 2014-04-14 2023-08-12 Not clear
Matthew P Parsons, Rujun Kang, Caodu Buren, Alejandro Dau, Amber L Southwell, Crystal N Doty, Shaun S Sanders, Michael R Hayden, Lynn A Raymon. Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin. The Journal of biological chemistry. vol 289. issue 6. 2014-04-07. PMID:24347167. thus, unlike in previous studies in the hippocampus, enhanced or decreased psd-95 clustering alone was insufficient to drive ampa or nmda receptors into or out of spn synapses. 2014-04-07 2023-08-12 mouse
C Procaccini, M Maksimovic, T Aitta-Aho, E R Korpi, A-M Linde. Reversal of novelty-induced hyperlocomotion and hippocampal c-Fos expression in GluA1 knockout male mice by the mGluR2/3 agonist LY354740. Neuroscience. vol 250. 2014-04-04. PMID:23867766. as a putative model for these disorders, a mouse line lacking the glua1 subunit (glua1-ko) of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) glutamate receptor displays a robust novelty-induced hyperlocomotion associated with excessive neuronal activation in the hippocampus. 2014-04-04 2023-08-12 mouse
E Soares, R D Prediger, S Nunes, A A Castro, S D Viana, C Lemos, C M De Souza, P Agostinho, R A Cunha, E Carvalho, C A Fontes Ribeiro, F Reis, F C Pereir. Spatial memory impairments in a prediabetic rat model. Neuroscience. vol 250. 2014-04-04. PMID:23912035. importantly, hsu animals exhibited increased hippocampal levels of ampa and nmda receptor subunits glua1 and glun1, respectively, whereas the levels of protein markers related to nerve terminals (synaptophysin) and oxidative stress/inflammation (hne, rage, tnf-α) remained unaltered. 2014-04-04 2023-08-12 rat
Tiwalade Sobayo, David J Mogu. Rapid onset of a kainate-induced mirror focus in rat hippocampus is mediated by contralateral AMPA receptors. Epilepsy research. vol 106. issue 1-2. 2014-03-19. PMID:23668947. rapid onset of a kainate-induced mirror focus in rat hippocampus is mediated by contralateral ampa receptors. 2014-03-19 2023-08-12 rat
Tiwalade Sobayo, David J Mogu. Rapid onset of a kainate-induced mirror focus in rat hippocampus is mediated by contralateral AMPA receptors. Epilepsy research. vol 106. issue 1-2. 2014-03-19. PMID:23668947. by tracking the order of seizure onset, the probability that a hippocampal seizure would propagate across commissural fibers prior to any thalamic seizure activity was significantly reduced in the cnqx group compared to control and ubp groups suggesting that the ampa receptor mediated component responsible for mirror focus development was also necessary for the spread of ictal activity via the commissural fibers. 2014-03-19 2023-08-12 rat