All Relations between \u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and hippocampus

Publication Sentence Publish Date Extraction Date Species
Edoardo Moretto, Federico Miozzo, Anna Longatti, Caroline Bonnet, Francoise Coussen, Fanny Jaudon, Lorenzo A Cingolani, Maria Passafar. The tetraspanin TSPAN5 regulates AMPAR exocytosis by interacting with the AP4 complex. eLife. vol 12. 2023-02-16. PMID:36795458. we found that, in rat hippocampal neurons, an intracellular pool of the tetraspanin tspan5 promotes exocytosis of ampa receptors without affecting their internalisation. 2023-02-16 2023-08-14 rat
Leigh Clements, Amy Alexander, Kirsty Hamilton, Andrew Irving, Jenni Harve. G-protein coupled estrogen receptor (GPER1) activation promotes synaptic insertion of AMPA receptors and induction of chemical LTP at hippocampal temporoammonic-CA1 synapses. Molecular brain. vol 16. issue 1. 2023-01-28. PMID:36709268. g-protein coupled estrogen receptor (gper1) activation promotes synaptic insertion of ampa receptors and induction of chemical ltp at hippocampal temporoammonic-ca1 synapses. 2023-01-28 2023-08-14 Not clear
Dirk Montag, Laura Pelz, Fritz G Rathje. Lack of the Ig cell adhesion molecule BT-IgSF (IgSF11) induced behavioral changes in the open maze, water maze and resident intruder test. PloS one. vol 18. issue 1. 2023-01-06. PMID:36607983. in the nervous system, bt-igsf regulates the stability of ampa receptors in the membrane of cultured hippocampal neurons, modulates the connectivity of chandelier cells and controls gap junction-mediated astrocyte-astrocyte communication. 2023-01-06 2023-08-14 mouse
Laura Bellingacci, Martina Tallarico, Andrea Mancini, Alfredo Megaro, Carmen De Caro, Rita Citraro, Giovambattista De Sarro, Alessandro Tozzi, Massimiliano Di Filippo, Miriam Sciaccaluga, Emilio Russo, Antonio Leo, Cinzia Cost. Non-competitive AMPA glutamate receptors antagonism by perampanel as a strategy to counteract hippocampal hyper-excitability and cognitive deficits in cerebral amyloidosis. Neuropharmacology. 2022-12-12. PMID:36502868. non-competitive ampa glutamate receptors antagonism by perampanel as a strategy to counteract hippocampal hyper-excitability and cognitive deficits in cerebral amyloidosis. 2022-12-12 2023-08-14 mouse
Jens Stepan, Daniel E Heinz, Frederik Dethloff, Thomas Bajaj, Andreas Zellner, Kathrin Hafner, Svenja Wiechmann, Sarah Mackert, Yara Mecdad, Michael Rabenstein, Tim Ebert, Silvia Martinelli, Alexander S Häusl, Maximilian L Pöhlmann, Anke Hermann, Xiao Ma, Hermann Pavenstädt, Mathias V Schmidt, Alexandra Philipsen, Chris W Turck, Jan M Deussing, Bernhard Kuster, Michael C Wehr, Valentin Stein, Joachim Kremerskothen, Carsten T Wotjak, Nils C Gasse. Hippo-released WWC1 facilitates AMPA receptor regulatory complexes for hippocampal learning. Cell reports. vol 41. issue 10. 2022-12-08. PMID:36476872. hippo-released wwc1 facilitates ampa receptor regulatory complexes for hippocampal learning. 2022-12-08 2023-08-14 mouse
Dexiao Zhu, Jian Zhang, Fei Gao, Mei Hu, Jack Hashem, Chu Che. Augmentation of 2-arachidonoylglycerol signaling in astrocytes maintains synaptic functionality by regulation of miRNA-30b. Experimental neurology. 2022-12-08. PMID:36481187. here, we provide evidence that pharmacological inactivation of magl suppresses hippocampal expression of mir-30b, a small non-coding microrna, and upregulates expression of its targets, including ephrin type-b receptor 2 (ephb2), sirtuin1 (sirt1), and glutamate ionotropic receptor ampa type subunit 2 (glua2). 2022-12-08 2023-08-14 Not clear
Wei Wei, Sophie T Yount, Zachary D Allen, Katherine F Bechdol, Weiming Xia, Huanbiao Mo, Angela M Mab. The mevalonate suppressor δ-tocotrienol increases AMPA receptor-mediated neurotransmission. Biochemical and biophysical research communications. vol 638. 2022-11-29. PMID:36446153. here, we found that δ-tocotrienol increased surface levels of glua1 but not the glua2 ampa receptor subunit in primary hippocampal neurons. 2022-11-29 2023-08-14 Not clear
Rocio Alfaro-Ruiz, Carolina Aguado, Alejandro Martín-Belmonte, Ana Esther Moreno-Martínez, Jesús Merchán-Rubira, Félix Hernández, Jesús Ávila, Yugo Fukazawa, Rafael Lujá. Alteration in the Synaptic and Extrasynaptic Organization of AMPA Receptors in the Hippocampus of P301S Tau Transgenic Mice. International journal of molecular sciences. vol 23. issue 21. 2022-11-11. PMID:36362317. alteration in the synaptic and extrasynaptic organization of ampa receptors in the hippocampus of p301s tau transgenic mice. 2022-11-11 2023-08-14 mouse
Elisabetta Gerace, Lorenzo Polenzani, Maurizio Magnani, Elisa Zianni, Gabriella Stocca, Fabrizio Gardoni, Domenico E Pellegrini-Giampietro, Renato Corradett. Antidepressant-induced increase in GluA2 expression does not translate in changes of AMPA receptor-mediated synaptic transmission at CA3/CA1 synapses in rats. Neuropharmacology. 2022-11-05. PMID:36334766. chronic treatment with serotonin selective reuptake inhibitors or tryciclic antidepressant drugs in rodents has been shown to increase the expression of glua1 and/or glua2 ampa receptor (ampar) subunits in several brain areas, including the hippocampus. 2022-11-05 2023-08-14 rat
Mohamad Azmeer Effendy, Suleiman Yunusa, Noorul Hamizah Mat, Ahmad Tarmizi Che Has, Christian P Müller, Zurina Hassa. The role of AMPA and NMDA receptors in mitragynine effects on hippocampal synaptic plasticity. Behavioural brain research. 2022-10-23. PMID:36273648. the role of ampa and nmda receptors in mitragynine effects on hippocampal synaptic plasticity. 2022-10-23 2023-08-14 rat
Narongrit Thongon, Siriporn Chamniansawa. Hippocampal synaptic dysfunction and spatial memory impairment in omeprazole-treated rats. Metabolic brain disease. 2022-10-01. PMID:36181652. we examined the hippocampal protein expression of synaptic plasticity proteins, including the ampa receptor subunit glua1, postsynaptic density-95 (psd-95), and activity-regulated cytoskeleton-associated protein (arc), and the hippocampal expression and localization of androgen receptor (ar). 2022-10-01 2023-08-14 rat
Abhishek Mishra, Rubal Singla, Rohit Kumar, AmitRaj Sharma, Rupa Joshi, Phulen Sarma, Gurjeet Kaur, Manisha Prajapat, Alka Bhatia, Bikash Medh. Granulocyte Colony-Stimulating Factor Improved Core Symptoms of Autism Spectrum Disorder via Modulating Glutamatergic Receptors in the Prefrontal Cortex and Hippocampus of Rat Brains. ACS chemical neuroscience. 2022-09-27. PMID:36166499. the upregulated expression of nmda and ampa both in the prefrontal cortex as well as hippocampus was alleviated by the g-csf thereby validating its anti-inflammatory and excitoprotective properties. 2022-09-27 2023-08-14 rat
Anna Maria Tartaglione, Melania Maria Serafini, Francesca Ferraris, Andrea Raggi, Annalisa Mirabello, Rita Di Benedetto, Laura Ricceri, Miriam Midali, Francesco Cubadda, Luisa Minghetti, Barbara Viviani, Gemma Calamandre. Short- and Long-Term Effects of Suboptimal Selenium Intake and Developmental Lead Exposure on Behavior and Hippocampal Glutamate Receptors in a Rat Model. Nutrients. vol 14. issue 16. 2022-08-26. PMID:36014775. in rat offspring, the assessment of motor, emotional, and cognitive endpoints at different life stages were complemented by the evaluation of the expression and synaptic distribution of nmda and ampa receptor subunits at post-natal day (pnd) 23 and 70 in the hippocampus. 2022-08-26 2023-08-14 rat
Anna Maria Tartaglione, Melania Maria Serafini, Francesca Ferraris, Andrea Raggi, Annalisa Mirabello, Rita Di Benedetto, Laura Ricceri, Miriam Midali, Francesco Cubadda, Luisa Minghetti, Barbara Viviani, Gemma Calamandre. Short- and Long-Term Effects of Suboptimal Selenium Intake and Developmental Lead Exposure on Behavior and Hippocampal Glutamate Receptors in a Rat Model. Nutrients. vol 14. issue 16. 2022-08-26. PMID:36014775. from the molecular point of view, we observed hippocampal alterations in nmda (glun2b and glun1) and ampa receptor subunit trafficking to the post-synapse in male rats only. 2022-08-26 2023-08-14 rat
Jia-Xuan Han, Chen-Xi Wen, Rui Sun, Meng-Yu Tang, Xiao-Ming Li, Hong Lia. The dorsal hippocampal CA3 regulates spatial reference memory through the CtBP2/GluR2 pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36. issue 9. 2022-08-15. PMID:35969153. consistently, ctbp2 deficiency altered the mrna expression of multiple endocytosis-regulatory genes, and ctbp2 knockdown in primary hippocampal neurons enhanced glur2-containing ampa receptor endocytosis. 2022-08-15 2023-08-14 Not clear
Sarah E Svirsky, Nicholas S Ranellone, Madison Parry, Erik Holets, Jeremy Henchir, Youming Li, Shaun W Carlson, C Edward Dixo. All-trans retinoic acid has limited therapeutic effects on cognition and hippocampal protein expression after controlled cortical impact. Neuroscience. 2022-07-25. PMID:35878718. hippocampal expression of synaptic plasticity proteins neurogranin (ng), and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor glua1 sub-unit, as well as ra signaling proteins stra6, adlh1a1, cyp26a1 and cyp26b1 were evaluated by western blot at 2-weeks post-injury. 2022-07-25 2023-08-14 rat
K Hrivikova, D Zelena, J Graban, A Puhova, I Miklya, D Balazsfi, D Jezov. Chronic treatment with enhancer drugs modifies the gene expression of selected parameters related to brain plasticity in rats under stress conditions. Neurochemistry international. 2022-07-19. PMID:35853552. the gene expression of glur1, an ampa receptor subunit was reduced by repeated treatment with deprenyl in the hippocampus and with both bpap and deprenyl in the prefrontal cortex. 2022-07-19 2023-08-14 rat
Darwin Contreras, Ricardo Piña, Claudia Carvallo, Felipe Godoy, Gonzalo Ugarte, Marc Zeise, Carlos Rozas, Bernardo Morale. Methylphenidate Restores Behavioral and Neuroplasticity Impairments in the Prenatal Nicotine Exposure Mouse Model of ADHD: Evidence for Involvement of AMPA Receptor Subunit Composition and Synaptic Spine Morphology in the Hippocampus. International journal of molecular sciences. vol 23. issue 13. 2022-07-09. PMID:35806103. methylphenidate restores behavioral and neuroplasticity impairments in the prenatal nicotine exposure mouse model of adhd: evidence for involvement of ampa receptor subunit composition and synaptic spine morphology in the hippocampus. 2022-07-09 2023-08-14 mouse
Ying Han, Le Chen, Jingyun Liu, Jie Chen, Chunyang Wang, Yu Guo, Xuebin Yu, Chenghong Zhang, Haiying Chu, Haiying M. A Class I HDAC Inhibitor Rescues Synaptic Damage and Neuron Loss in APP-Transfected Cells and APP/PS1 Mice through the GRIP1/AMPA Pathway. Molecules (Basel, Switzerland). vol 27. issue 13. 2022-07-09. PMID:35807406. based on these results, hdacs are involved in the early process of synaptic defects in ad models, and bg45 may rescue synaptic damage and the loss of hippocampal neurons by specifically inhibiting hdac1, hdac2, and hdac3, thereby modulating ampa receptor transduction, increasing synapse-related gene expression, and finally enhancing the function of excitatory synapses. 2022-07-09 2023-08-14 mouse
Mi Kyoung Seo, Jung An Lee, Sehoon Jeong, Dae-Hyun Seog, Jung Goo Lee, Sung Woo Par. Effects of Chronic LY341495 on Hippocampal mTORC1 Signaling in Mice with Chronic Unpredictable Stress-Induced Depression. International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35742857. cus significantly reduced the phosphorylation of mtorc1 and downstream effectors [eukaryotic translation initiation factor 4e-binding protein 1 (4e-bp-1) and small ribosomal protein 6 (s6)], as well as the expression of synaptic proteins postsynaptic density-95 (psd-95) and ampa receptor subunit glur1 (glua1) in the hippocampus. 2022-06-24 2023-08-14 mouse