| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Karine Pozo, Lorenzo A Cingolani, Silvia Bassani, Fanny Laurent, Maria Passafaro, Yukiko God. β3 integrin interacts directly with GluA2 AMPA receptor subunit and regulates AMPA receptor expression in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 4. 2012-03-28. PMID:22232691. |
in hippocampal neurons, the β3 integrin subtype is required for homeostatic synaptic scaling of ampa receptors (ampars) induced by chronic activity deprivation. |
2012-03-28 |
2023-08-12 |
mouse |
| Laura Dazzi, Alessandra Matzeu, Giovanni Biggi. Role of ionotropic glutamate receptors in the regulation of hippocampal norepinephrine output in vivo. Brain research. vol 1386. 2012-03-12. PMID:21362410. |
the gaba(a) receptor antagonist bicuculline (10μm) prevented the decrease in hippocampal norepinephrine output induced by either nmda or 10μm ampa. |
2012-03-12 |
2023-08-12 |
rat |
| Zilong Qiu, Emily L Sylwestrak, David N Lieberman, Yan Zhang, Xin-Yu Liu, Anirvan Ghos. The Rett syndrome protein MeCP2 regulates synaptic scaling. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 3. 2012-03-09. PMID:22262897. |
here we report that bicuculline-induced increase in neuronal activity leads to a decrease in mepsc amplitude and a decrease in expression of the ampa receptor subunit glur2 in rat hippocampal cultures. |
2012-03-09 |
2023-08-12 |
rat |
| Takamitsu Unoki, Shinji Matsuda, Wataru Kakegawa, Ngo Thai Bich Van, Kazuhisa Kohda, Atsushi Suzuki, Yuji Funakoshi, Hiroshi Hasegawa, Michisuke Yuzaki, Yasunori Kanah. NMDA receptor-mediated PIP5K activation to produce PI(4,5)P₂ is essential for AMPA receptor endocytosis during LTD. Neuron. vol 73. issue 1. 2012-03-05. PMID:22243752. |
nmda-induced ampa receptor endocytosis and low-frequency stimulation-induced ltd were completely blocked by inhibiting the association between dephosphorylated pip5kγ661 and ap-2 and by overexpression of a kinase-dead pip5kγ661 mutant in hippocampal neurons. |
2012-03-05 |
2023-08-12 |
Not clear |
| Takamitsu Unoki, Shinji Matsuda, Wataru Kakegawa, Ngo Thai Bich Van, Kazuhisa Kohda, Atsushi Suzuki, Yuji Funakoshi, Hiroshi Hasegawa, Michisuke Yuzaki, Yasunori Kanah. NMDA receptor-mediated PIP5K activation to produce PI(4,5)P₂ is essential for AMPA receptor endocytosis during LTD. Neuron. vol 73. issue 1. 2012-03-05. PMID:22243752. |
therefore, nmda receptor activation controls ampa receptor endocytosis during hippocampal ltd by regulating pip5kγ661 activity at postsynapses. |
2012-03-05 |
2023-08-12 |
Not clear |
| Fabrizio Gardoni, Elisa Zianni, Anna Eramo, Pier Luigi Canonico, Monica Di Luc. Effect of rasagiline on the molecular composition of the excitatory postsynaptic density. European journal of pharmacology. vol 670. issue 2-3. 2012-02-27. PMID:21946113. |
in hippocampus as well as in striatum, rasagiline induces a significant reduction of synaptic levels of nr2a-containing nmda receptors and in hippocampal slices it also significantly decreases synaptic levels of glur1-containing ampa receptors. |
2012-02-27 |
2023-08-12 |
Not clear |
| Orla Watters, John J O'Conno. A role for tumor necrosis factor-α in ischemia and ischemic preconditioning. Journal of neuroinflammation. vol 8. 2012-02-23. PMID:21810263. |
studies with organotypic hippocampal cultures and mixed primary hippocampal cultures have shown that prior incubation with low concentrations of glutamate and tnf-α increase the resistance of neurones to a subsequent insult from glutamate, ampa and nmda, while co-exposure of tnf-α and for example ampa may have neuroprotective effects compared to cultures exposed to excitotoxic agents alone. |
2012-02-23 |
2023-08-12 |
Not clear |
| Elias Pavlopoulos, Pierre Trifilieff, Vivien Chevaleyre, Luana Fioriti, Sakellarios Zairis, Andrew Pagano, Gaël Malleret, Eric R Kande. Neuralized1 activates CPEB3: a function for nonproteolytic ubiquitin in synaptic plasticity and memory storage. Cell. vol 147. issue 6. 2012-02-03. PMID:22153079. |
in hippocampal cultures, cpeb3 activated by neuralized1-mediated ubiquitination leads both to the growth of new dendritic spines and to an increase of the glua1 and glua2 subunits of ampa receptors, two cpeb3 targets essential for synaptic plasticity. |
2012-02-03 |
2023-08-12 |
mouse |
| Jean-Marie C Bouteiller, Sushmita L Allam, Eric Y Hu, Renaud Greget, Nicolas Ambert, Anne Florence Keller, Serge Bischoff, Michel Baudry, Theodore W Berge. Integrated multiscale modeling of the nervous system: predicting changes in hippocampal network activity by a positive AMPA receptor modulator. IEEE transactions on bio-medical engineering. vol 58. issue 10. 2012-01-31. PMID:21642035. |
integrated multiscale modeling of the nervous system: predicting changes in hippocampal network activity by a positive ampa receptor modulator. |
2012-01-31 |
2023-08-12 |
Not clear |
| Elek Molná. Long-term potentiation in cultured hippocampal neurons. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21807105. |
for example, ltp in dissociated hippocampal neuronal cultures is also dependent on ca(2+) influx through post-synaptic nmda receptors, subsequent activation and autophosphorylation of the ca(2+)/calmodulin-dependent protein kinase ii (camkii) and an increase in alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (ampa) receptor insertion at the post-synaptic membrane. |
2012-01-26 |
2023-08-12 |
Not clear |
| Elek Molná. Long-term potentiation in cultured hippocampal neurons. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21807105. |
this review focuses on key features of various ltp induction protocols in dissociated hippocampal neuronal cultures and the applications of these plasticity models for the investigation of activity-induced changes in native ampa receptors. |
2012-01-26 |
2023-08-12 |
Not clear |
| Hey-Kyoung Lee, Alfredo Kirkwoo. AMPA receptor regulation during synaptic plasticity in hippocampus and neocortex. Seminars in cell & developmental biology. vol 22. issue 5. 2012-01-26. PMID:21856433. |
ampa receptor regulation during synaptic plasticity in hippocampus and neocortex. |
2012-01-26 |
2023-08-12 |
rabbit |
| Xiangmin Peng, Jeeyong Kim, Zhigang Zhou, David J Fink, Marina Mat. Neuronal Nogo-A regulates glutamate receptor subunit expression in hippocampal neurons. Journal of neurochemistry. vol 119. issue 6. 2012-01-26. PMID:21985178. |
taken together the results suggest that transcription and translation of nogo-a in hippocampal neurons is regulated by a signaling through ngr1, and that interactions between neuronal nogo-a and ngr1 regulate glutamatergic transmission by altering nmda and ampa receptor levels through an rapamycin-sensitive mtor-dependent translation mechanism. |
2012-01-26 |
2023-08-12 |
Not clear |
| Yan Xia, George S Portugal, Amanda K Fakira, Zara Melyan, Rachael Neve, H Thomas Lee, Scott J Russo, Jie Liu, Jose A Moró. Hippocampal GluA1-containing AMPA receptors mediate context-dependent sensitization to morphine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 45. 2012-01-04. PMID:22072679. |
hippocampal glua1-containing ampa receptors mediate context-dependent sensitization to morphine. |
2012-01-04 |
2023-08-12 |
mouse |
| Christian Peters, Braulio Muñoz, Fernando J Sepúlveda, Juan Urrutia, Mauricio Quiroz, Sandra Luza, Giancarlo V De Ferrari, Luis G Aguayo, Carlos Opaz. Biphasic effects of copper on neurotransmission in rat hippocampal neurons. Journal of neurochemistry. vol 119. issue 1. 2011-10-31. PMID:21824141. |
interestingly, when it is applied for 3 h to hippocampal neurons it mainly increases the frequency and amplitude of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa)ergic currents (control: 0.21 ± 0.05 hz/22.9 ± 1.3 pa; copper: 0.68 ± 0.16 hz/30.5 ± 2.5 pa), intracellular calcium transients (control: 0.05 ± 0.013 hz; copper: 0.11 ± 0.02 hz) and evoked ampa currents (control: ec50 8.3 ± 0.5 μm; copper: ec50 2.9 ± 0.2 μm). |
2011-10-31 |
2023-08-12 |
rat |
| Elena A Kharlamov, Eka Lepsveridze, Maia Meparishvili, Revaz O Solomonia, Bo Lu, Eric R Miller, Kevin M Kelly, Zakaria Mtchedlishvil. Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy. Epilepsy research. vol 95. issue 1-2. 2011-10-18. PMID:21439793. |
in the present study, we investigated long-term changes in the protein expression of gaba(a)r α1, α4, γ2, and δ subunits, nmda (nr2b) and ampa (glur1) receptor subunits, and heat shock proteins (hsp70 and hsp90) in the hippocampus of sprague-dawley rats evaluated by western blotting in controls, cci-injured animals without pte (cci group), and cci-injured animals with pte (pte group). |
2011-10-18 |
2023-08-12 |
rat |
| Claudia A Grillo, Gerardo G Piroli, Ashlie N Evans, Victoria A Macht, Steven P Wilson, Karen A Scott, Randall R Sakai, David D Mott, Lawrence P Reaga. Obesity/hyperleptinemic phenotype adversely affects hippocampal plasticity: effects of dietary restriction. Physiology & behavior. vol 104. issue 2. 2011-10-14. PMID:21036186. |
both of these paradigms restored ltp in the ca1 region and reversed the decreases in the phosphorylated/total ratio of glua1 ser845 ampa receptor subunit expression observed in the hippocampus of hypo-iras rats. |
2011-10-14 |
2023-08-12 |
rat |
| H Wang, M I Dávila-García, W Yarl, M C Gondré-Lewi. Gestational nicotine exposure regulates expression of AMPA and NMDA receptors and their signaling apparatus in developing and adult rat hippocampus. Neuroscience. vol 188. 2011-10-12. PMID:21596105. |
gestational nicotine exposure regulates expression of ampa and nmda receptors and their signaling apparatus in developing and adult rat hippocampus. |
2011-10-12 |
2023-08-12 |
rat |
| H Wang, M I Dávila-García, W Yarl, M C Gondré-Lewi. Gestational nicotine exposure regulates expression of AMPA and NMDA receptors and their signaling apparatus in developing and adult rat hippocampus. Neuroscience. vol 188. 2011-10-12. PMID:21596105. |
the effects of nicotine persisted in p63 young adult brains which exhibited significantly downregulated glur2, nr1, and nr2c expression levels in hippocampal homogenates and a considerably muted overall distribution of [³h]ampa binding in areas ca1, ca2 and ca3, and the dentate gyrus. |
2011-10-12 |
2023-08-12 |
rat |
| Dai Mitsushima, Kouji Ishihara, Akane Sano, Helmut W Kessels, Takuya Takahash. Contextual learning requires synaptic AMPA receptor delivery in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 30. 2011-10-03. PMID:21746893. |
contextual learning requires synaptic ampa receptor delivery in the hippocampus. |
2011-10-03 |
2023-08-12 |
rat |