| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mark R Etherton, Katsuhiko Tabuchi, Manu Sharma, Jaewon Ko, Thomas C Südho. An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus. The EMBO journal. vol 30. issue 14. 2011-09-29. PMID:21642956. |
an autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs ampa receptor-mediated synaptic transmission in hippocampus. |
2011-09-29 |
2023-08-12 |
mouse |
| Mark R Etherton, Katsuhiko Tabuchi, Manu Sharma, Jaewon Ko, Thomas C Südho. An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus. The EMBO journal. vol 30. issue 14. 2011-09-29. PMID:21642956. |
specifically, the r704c mutation caused a major and selective decrease in ampa receptor-mediated synaptic transmission in pyramidal neurons of the hippocampus, without similarly changing nmda or gaba receptor-mediated synaptic transmission, and without detectably altering presynaptic neurotransmitter release. |
2011-09-29 |
2023-08-12 |
mouse |
| Luca Caracciolo, Alessandro Barbon, Sara Palumbo, Cristina Mora, Christopher D Toscano, Francesca Bosetti, Sergio Barlat. Altered mRNA editing and expression of ionotropic glutamate receptors after kainic acid exposure in cyclooxygenase-2 deficient mice. PloS one. vol 6. issue 5. 2011-09-21. PMID:21589914. |
the expression of ampa glur2, glur3 and ka glur6 was increased in vehicle-injected cox-2(-/-) mice compared to wild type (wt) mice in hippocampus and cortex, whereas gene expression of nmda receptors was decreased. |
2011-09-21 |
2023-08-12 |
mouse |
| Luca Caracciolo, Alessandro Barbon, Sara Palumbo, Cristina Mora, Christopher D Toscano, Francesca Bosetti, Sergio Barlat. Altered mRNA editing and expression of ionotropic glutamate receptors after kainic acid exposure in cyclooxygenase-2 deficient mice. PloS one. vol 6. issue 5. 2011-09-21. PMID:21589914. |
ka treatment decreased the expression of ampa, ka and nmda receptors in the hippocampus, with a significant effect in cox-2(-/-) mice. |
2011-09-21 |
2023-08-12 |
mouse |
| Xiaojun Xiang, Wen Huang, Colin N Haile, Therese A Koste. Hippocampal GluR1 associates with behavior in the elevated plus maze and shows sex differences. Behavioural brain research. vol 222. issue 2. 2011-09-20. PMID:21497621. |
many intracellular proteins, including α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor subunit glur1 and the cyclic amp response element-binding protein (creb), in hippocampus contribute to memory formation. |
2011-09-20 |
2023-08-12 |
rat |
| A Vazdarjanova, K Bunting, N Muthusamy, C Bergso. Calcyon upregulation in adolescence impairs response inhibition and working memory in adulthood. Molecular psychiatry. vol 16. issue 6. 2011-09-19. PMID:21403673. |
brain regional immunoblots revealed a prominent downregulation of ampa glur1 subunits in hippocampus and glur2/3 subunits in hippocampus and prefrontal cortex of the cal(oe) mice. |
2011-09-19 |
2023-08-12 |
mouse |
| Fabio Fumagalli, Matteo Pasini, Alexander Sartorius, Rosine Scherer, Giorgio Racagni, Marco A Riva, Peter Gas. Repeated electroconvulsive shock (ECS) alters the phosphorylation of glutamate receptor subunits in the rat hippocampus. The international journal of neuropsychopharmacology. vol 13. issue 9. 2011-09-01. PMID:20497625. |
chronic ecs produced a marked increase in the phosphorylation of the regulatory nmda receptor subunit nr2b (ser1303) and the ampa receptor subunit glur-a (ser831) in the hippocampus, with no effects on the obligatory subunit nr1. |
2011-09-01 |
2023-08-12 |
rat |
| Marija V Turovskaya, Egor A Turovsky, Valery P Zinchenko, Sergei G Levin, Alina A Shamsutdinova, Oleg V Godukhi. Repeated brief episodes of hypoxia modulate the calcium responses of ionotropic glutamate receptors in hippocampal neurons. Neuroscience letters. vol 496. issue 1. 2011-08-26. PMID:21458539. |
the main result of our study is that brief hypoxic episodes progressively depress the [ca(2+)](i) increases induced by agonists of ampa and nmda glutamate receptors in cultured hippocampal neurons. |
2011-08-26 |
2023-08-12 |
rat |
| Anders S Kristensen, Meagan A Jenkins, Tue G Banke, Arne Schousboe, Yuichi Makino, Richard C Johnson, Richard Huganir, Stephen F Trayneli. Mechanism of Ca2+/calmodulin-dependent kinase II regulation of AMPA receptor gating. Nature neuroscience. vol 14. issue 6. 2011-08-17. PMID:21516102. |
we show that camkii increases the conductance of native heteromeric ampa receptors in mouse hippocampal neurons through phosphorylation of ser831. |
2011-08-17 |
2023-08-12 |
mouse |
| Nelson Rebola, Mario Carta, Frederic Lanore, Christophe Blanchet, Christophe Mull. NMDA receptor-dependent metaplasticity at hippocampal mossy fiber synapses. Nature neuroscience. vol 14. issue 6. 2011-08-17. PMID:21532578. |
hippocampal mossy fiber synapses have been reported to lack nmda receptor (nmdar)-dependent long-term potentiation (ltp) of ampa excitatory postsynaptic currents (epscs), unlike conventional glutamatergic synapses. |
2011-08-17 |
2023-08-12 |
mouse |
| Martin B Gill, Akihiko S Kato, Matthew F Roberts, Hong Yu, He Wang, Susumu Tomita, David S Bred. Cornichon-2 modulates AMPA receptor-transmembrane AMPA receptor regulatory protein assembly to dictate gating and pharmacology. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 18. 2011-08-05. PMID:21543622. |
in both rat and mouse hippocampal neurons, cnih-2 also associates with ampa receptors on the neuronal surface in a γ-8-dependent manner to dictate receptor pharmacology. |
2011-08-05 |
2023-08-12 |
mouse |
| Elva Día. SynDIG1 regulation of synaptic AMPA receptor targeting. Communicative & integrative biology. vol 3. issue 4. 2011-07-14. PMID:20798822. |
the discovery that the transmembrane protein stargazin controls synaptic ampa-r targeting represented a major paradigm shift in the field.11 my colleagues and i recently reported the discovery of a novel type ii transmembrane protein syndig1 (synapse differentiation induced gene i) that functions as a critical regulator of excitatory synapse development in dissociated rat hippocampal neurons.12 specifically, knock-down of syndig1 in cultured neurons reduces ampa receptor content at developing synapses by approximately 50% as determined by immunocytochemistry and electrophysiology.12 the magnitude of this effect matches that of tarps and psd-95 identifying syndig1 as a previously unknown central regulator of postsynaptic ampa receptor targeting. |
2011-07-14 |
2023-08-12 |
rat |
| Chelsea S Goulton, Anna R Patten, John R Kerr, D Steven Ker. Pharmacological Preconditioning with GYKI 52466: A Prophylactic Approach to Neuroprotection. Frontiers in neuroscience. vol 4. 2011-07-14. PMID:20953290. |
we have previously shown that in vitro preconditioning with the ampa receptor antagonist gyki 52466 induces tolerance to kainic acid (ka) toxicity in hippocampus. |
2011-07-14 |
2023-08-12 |
Not clear |
| James J Bae, Yun-Yan Xiang, Alonso Martinez-Canabal, Paul W Frankland, Burton B Yang, Wei-Yang L. Increased transforming growth factor-β1 modulates glutamate receptor expression in the hippocampus. International journal of physiology, pathophysiology and pharmacology. vol 3. issue 1. 2011-07-14. PMID:21479098. |
in addition, the increased tgf-β1 augmented the expression of some key subunits of α-amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (ampa) and n-methyl-d-aspartate (nmda) receptors in the hippocampus. |
2011-07-14 |
2023-08-12 |
mouse |
| Dorian Caudal, Bill P Godsil, François Mailliet, Damien Bergerot, Thérèse M Ja. Acute stress induces contrasting changes in AMPA receptor subunit phosphorylation within the prefrontal cortex, amygdala and hippocampus. PloS one. vol 5. issue 12. 2011-07-05. PMID:21170339. |
acute stress induces contrasting changes in ampa receptor subunit phosphorylation within the prefrontal cortex, amygdala and hippocampus. |
2011-07-05 |
2023-08-12 |
rat |
| Dorian Caudal, Bill P Godsil, François Mailliet, Damien Bergerot, Thérèse M Ja. Acute stress induces contrasting changes in AMPA receptor subunit phosphorylation within the prefrontal cortex, amygdala and hippocampus. PloS one. vol 5. issue 12. 2011-07-05. PMID:21170339. |
using an acute inescapable stress protocol with rats, we found opposite effects on ampa receptor phosphorylation in the medial prefrontal cortex (mpfc) and dorsal hippocampus (dh) compared to the amygdala and ventral hippocampus (vh). |
2011-07-05 |
2023-08-12 |
rat |
| Douglas A Schober, Martin B Gill, Hong Yu, Douglas L Gernert, Matthew W Jeffries, Paul L Ornstein, Akihiko S Kato, Christian C Felder, David S Bred. Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators. The Journal of biological chemistry. vol 286. issue 15. 2011-06-28. PMID:21343286. |
coexpression of ampa receptors with cnih-2, which is expressed in the hippocampus and at low levels in the cerebellar purkinje neurons, confers partial sensitivity of [(3)h]-ly450295 potentiator binding to displacement by non-competitive antagonists. |
2011-06-28 |
2023-08-12 |
mouse |
| Douglas A Schober, Martin B Gill, Hong Yu, Douglas L Gernert, Matthew W Jeffries, Paul L Ornstein, Akihiko S Kato, Christian C Felder, David S Bred. Transmembrane AMPA receptor regulatory proteins and cornichon-2 allosterically regulate AMPA receptor antagonists and potentiators. The Journal of biological chemistry. vol 286. issue 15. 2011-06-28. PMID:21343286. |
autoradiography of [(3)h]-ly450295 binding to stargazer and γ-8-deficient mouse brain sections, demonstrates that tarps regulate the pharmacology of allosteric ampa potentiators and antagonists in the cerebellum and hippocampus, respectively. |
2011-06-28 |
2023-08-12 |
mouse |
| L Yu, K Rostamiani, Y-T Hsu, Y Wang, X Bi, M Baudr. Calpain-mediated regulation of stargazin in adult rat brain. Neuroscience. vol 178. 2011-06-27. PMID:21256931. |
changes in ampa receptors have been proposed to underlie changes in synaptic efficacy in hippocampus and other brain structures. |
2011-06-27 |
2023-08-12 |
rat |
| Pilar Monfort, Vicente Felip. Amyloid-β impairs, and ibuprofen restores, the cGMP pathway, synaptic expression of AMPA receptors and long-term potentiation in the hippocampus. Journal of Alzheimer's disease : JAD. vol 22. issue 3. 2011-06-09. PMID:20858955. |
amyloid-β impairs, and ibuprofen restores, the cgmp pathway, synaptic expression of ampa receptors and long-term potentiation in the hippocampus. |
2011-06-09 |
2023-08-12 |
rat |