| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Elyse Schauwecke. Neuroprotection by glutamate receptor antagonists against seizure-induced excitotoxic cell death in the aging brain. Experimental neurology. vol 224. issue 1. 2010-06-28. PMID:20353782. |
thus, we compared the effects of the nmda receptor antagonist, mk-801 and of the ampa receptor antagonist nbqx on hippocampal damage in the kainate model of seizure-induced excitotoxic cell death in young, middle-aged, and aged c57bl/6 and fvb/n mice, when given 90 min following kainate-induced status epilepticus. |
2010-06-28 |
2023-08-12 |
mouse |
| Zheng Li, Jihoon Jo, Jie-Min Jia, Shih-Ching Lo, Daniel J Whitcomb, Song Jiao, Kwangwook Cho, Morgan Shen. Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization. Cell. vol 141. issue 5. 2010-06-17. PMID:20510932. |
here, we show that activation of caspase-3 via mitochondria is required for ltd and ampa receptor internalization in hippocampal neurons. |
2010-06-17 |
2023-08-12 |
mouse |
| Elena Alberdi, M Victoria Sánchez-Gómez, Fabio Cavaliere, Alberto Pérez-Samartín, José Luis Zugaza, Ramón Trullas, María Domercq, Carlos Matut. Amyloid beta oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors. Cell calcium. vol 47. issue 3. 2010-06-15. PMID:20061018. |
importantly, chronic treatment with nanomolar concentration of abeta oligomers also induced nmda- and ampa receptor-dependent cell death in entorhinal cortex and hippocampal slice cultures. |
2010-06-15 |
2023-08-12 |
rat |
| Yanfang Rui, Jiaping Gu, Kuai Yu, H Criss Hartzell, James Q Zhen. Inhibition of AMPA receptor trafficking at hippocampal synapses by beta-amyloid oligomers: the mitochondrial contribution. Molecular brain. vol 3. 2010-06-15. PMID:20346152. |
inhibition of ampa receptor trafficking at hippocampal synapses by beta-amyloid oligomers: the mitochondrial contribution. |
2010-06-15 |
2023-08-12 |
Not clear |
| Pablo García-Junco-Clemente, Gloria Cantero, Leonardo Gómez-Sánchez, Pedro Linares-Clemente, José A Martínez-López, Rafael Luján, Rafael Fernández-Chacó. Cysteine string protein-alpha prevents activity-dependent degeneration in GABAergic synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 21. 2010-06-15. PMID:20505105. |
consistent with this, in hippocampal cultures from these mice, the frequency of miniature ipscs, caused by spontaneous gaba release, progressively declines, whereas the frequency of miniature excitatory ampa receptor-mediated currents (mepscs), caused by spontaneous release of glutamate, is normal. |
2010-06-15 |
2023-08-12 |
mouse |
| Jonathan G Hanle. Endosomal sorting of AMPA receptors in hippocampal neurons. Biochemical Society transactions. vol 38. issue 2. 2010-06-11. PMID:20298203. |
endosomal sorting of ampa receptors in hippocampal neurons. |
2010-06-11 |
2023-08-12 |
Not clear |
| Jonathan G Hanle. Endosomal sorting of AMPA receptors in hippocampal neurons. Biochemical Society transactions. vol 38. issue 2. 2010-06-11. PMID:20298203. |
an important mechanism for the regulation of excitatory synaptic transmission in the hippocampus involves tight control of ampar [ampa (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptor] trafficking to alter the number or subtype of synaptic receptors. |
2010-06-11 |
2023-08-12 |
Not clear |
| Yun Wang, Jing Wu, Zhiguo Wu, Qing Lin, Yun Yue, Li Fan. Regulation of AMPA receptors in spinal nociception. Molecular pain. vol 6. 2010-06-10. PMID:20092646. |
the functional properties of alpha-amino-3-hydroxy-5-methy-4-isoxazole propionate (ampa) receptors in different brain regions, such as hippocampus and cerebellum, have been well studied in vitro and in vivo. |
2010-06-10 |
2023-08-12 |
Not clear |
| Linda K Friedman, Menahem Sega. Early exposure of cultured hippocampal neurons to excitatory amino acids protects from later excitotoxicity. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 28. issue 2. 2010-06-09. PMID:19913087. |
here, we developed a "two hit" model in dissociated cultures of the rat hippocampus to test whether pre-exposure of immature neurons to high concentrations of glutamate, n-methyl-d-aspartic acid (nmda) or alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (ampa) during a relatively resistant period prevents neurons from dying following a second exposure to the same chemicals after neurons mature and become highly vulnerable to excitatory amino acids (eaas). |
2010-06-09 |
2023-08-12 |
rat |
| Sadia Oreland, Ingrid Nylander, Chris Pickerin. Prolonged maternal separation decreases granule cell number in the dentate gyrus of 3-week-old male rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 28. issue 2. 2010-06-09. PMID:20079421. |
maternal separation (ms) early in life affects many aspects of development and we have previously observed significant decreases in nmda and ampa receptor and elevated glutamate transporter expression in the hippocampus of ms360 animals relative to ms15. |
2010-06-09 |
2023-08-12 |
rat |
| M A Galic, K Riazi, A K Henderson, S Tsutsui, Q J Pittma. Viral-like brain inflammation during development causes increased seizure susceptibility in adult rats. Neurobiology of disease. vol 36. issue 2. 2010-06-03. PMID:19660546. |
whereas there was no alteration in adult hippocampal cytokine levels, we found a marked increase in nmda (nr2a and c) and ampa (glur1) glutamate receptor subunit mrna expression. |
2010-06-03 |
2023-08-12 |
rat |
| Sophie K Billa, Jie Liu, Nicole L Bjorklund, Namita Sinha, Yu Fu, Patricia Shinnick-Gallagher, Jose A Moró. Increased insertion of glutamate receptor 2-lacking alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors at hippocampal synapses upon repeated morphine administration. Molecular pharmacology. vol 77. issue 5. 2010-05-28. PMID:20159947. |
increased insertion of glutamate receptor 2-lacking alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (ampa) receptors at hippocampal synapses upon repeated morphine administration. |
2010-05-28 |
2023-08-12 |
Not clear |
| Ethan G Hughes, Xiaoyu Peng, Amy J Gleichman, Meizan Lai, Lei Zhou, Ryan Tsou, Thomas D Parsons, David R Lynch, Josep Dalmau, Rita J Balice-Gordo. Cellular and synaptic mechanisms of anti-NMDA receptor encephalitis. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 17. 2010-05-24. PMID:20427647. |
moreover, whole-cell patch-clamp recordings of miniature epscs in cultured rat hippocampal neurons showed that patients' antibodies specifically decreased synaptic nmdar-mediated currents, without affecting ampa receptor-mediated currents. |
2010-05-24 |
2023-08-12 |
rat |
| Tohru Yamakuni, Akira Nakajima, Yasushi Ohizum. [Preventive action of nobiletin, a constituent of AURANTII NOBILIS PERICARPIUM with anti-dementia activity, against amyloid-beta peptide-induced neurotoxicity expression and memory impairment]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 130. issue 4. 2010-05-20. PMID:20371995. |
pka-dependent signaling and membrane trafficking of ampa receptor subunit, glur1, which are known to be required for long-term potentiation (ltp), have been demonstrated to be inhibited by a sublethal concentration of abeta in cultured hippocampal neurons. |
2010-05-20 |
2023-08-12 |
mouse |
| Nasirud Din, Ishtiaq Ahmad, Ikram Ul Haq, Sana Elahi, Daniel C Hoessli, Abdul Rauf Shakoor. The function of GluR1 and GluR2 in cerebellar and hippocampal LTP and LTD is regulated by interplay of phosphorylation and O-GlcNAc modification. Journal of cellular biochemistry. vol 109. issue 3. 2010-05-19. PMID:20052678. |
hippocampal ltp involves phosphorylation of glur1 subunit of ampa receptor and its delivery to synapse whereas; ltd is the result of dephosphorylation and endocytosis of glur1 containing ampa receptor. |
2010-05-19 |
2023-08-12 |
Not clear |
| Peter R Moult, Alasdair Cross, Sandra D Santos, Ana-Luisa Carvalho, Yvonne Lindsay, Christopher N Connolly, Andrew J Irving, Nicholas R Leslie, Jenni Harve. Leptin regulates AMPA receptor trafficking via PTEN inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 11. 2010-05-18. PMID:20237279. |
it is well documented that trafficking of ampa receptors is pivotal for hippocampal synaptic plasticity (collingridge et al., 2004), but there is limited knowledge of how hormonal systems like leptin influence this process. |
2010-05-18 |
2023-08-12 |
Not clear |
| Peter R Moult, Alasdair Cross, Sandra D Santos, Ana-Luisa Carvalho, Yvonne Lindsay, Christopher N Connolly, Andrew J Irving, Nicholas R Leslie, Jenni Harve. Leptin regulates AMPA receptor trafficking via PTEN inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 11. 2010-05-18. PMID:20237279. |
here we show that leptin preferentially increases the cell surface expression of glur1 and the synaptic density of glur2-lacking ampa receptors in adult hippocampal slices. |
2010-05-18 |
2023-08-12 |
Not clear |
| Harald D Müller, Christian Berger, Stefan Schwab, Clemens Somme. Pravastatin treatment causes a shift in the balance of hippocampal neurotransmitter binding densities towards inhibition. Brain research. vol 1316. 2010-05-06. PMID:20026313. |
using quantitative receptor autoradiography, ligand binding densities of [(3)h]mk-801, [(3)h]ampa, and [(3)h]muscimol for labeling of nmda, ampa, and gaba(a) receptors were analyzed in sensorimotor cortices par1 and par2, the striatum, and the hippocampus. |
2010-05-06 |
2023-08-12 |
rat |
| Yuko Fukata, Kathryn L Lovero, Tsuyoshi Iwanaga, Atsushi Watanabe, Norihiko Yokoi, Katsuhiko Tabuchi, Ryuichi Shigemoto, Roger A Nicoll, Masaki Fukat. Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 8. 2010-04-05. PMID:20133599. |
a lack of lgi1 disrupts this synaptic protein connection and selectively reduces ampa receptor-mediated synaptic transmission in the hippocampus. |
2010-04-05 |
2023-08-12 |
mouse |
| Hey-Kyoung Lee, Kogo Takamiya, Kaiwen He, Lihua Song, Richard L Hugani. Specific roles of AMPA receptor subunit GluR1 (GluA1) phosphorylation sites in regulating synaptic plasticity in the CA1 region of hippocampus. Journal of neurophysiology. vol 103. issue 1. 2010-03-30. PMID:19906877. |
specific roles of ampa receptor subunit glur1 (glua1) phosphorylation sites in regulating synaptic plasticity in the ca1 region of hippocampus. |
2010-03-30 |
2023-08-12 |
mouse |