| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Evgenia Kalashnikova, Ramón A Lorca, Inderpreet Kaur, Gustavo A Barisone, Bonnie Li, Tatsuto Ishimaru, James S Trimmer, Durga P Mohapatra, Elva Día. SynDIG1: an activity-regulated, AMPA- receptor-interacting transmembrane protein that regulates excitatory synapse development. Neuron. vol 65. issue 1. 2010-03-23. PMID:20152115. |
here we identify a type ii transmembrane protein (syndig1) that regulates ampa receptor content at developing synapses in dissociated rat hippocampal neurons. |
2010-03-23 |
2023-08-12 |
rat |
| Chun-Yao Lee, Chih-Chuan Chen, Horng-Huei Lio. Levetiracetam inhibits glutamate transmission through presynaptic P/Q-type calcium channels on the granule cells of the dentate gyrus. British journal of pharmacology. vol 158. issue 7. 2010-03-11. PMID:19888964. |
the purpose of the present study was to investigate whether levetiracetam regulates ampa and nmda receptor-mediated excitatory synaptic transmission and to determine its site of action in the dentate gyrus (dg), the area of the hippocampus that regulates seizure activities. |
2010-03-11 |
2023-08-12 |
Not clear |
| Daniel Leite Góes Gitaí, Heloisa Nakashima Martinelli, Valeria Valente, Marilia G Alves Goulart Pereira, José Antonio Cortes Oliveira, Carol Fuzeti Elias, Jackson Cioni Bittencourt, João Pereira Leite, Claudio Miguel Costa-Neto, Norberto Garcia-Cairasco, Maria Luisa Paçó-Larso. Increased expression of GluR2-flip in the hippocampus of the Wistar audiogenic rat strain after acute and kindled seizures. Hippocampus. vol 20. issue 1. 2010-03-09. PMID:19330849. |
our findings on differential upregulation of glur2-flip isoform in the hippocampus of wars displaying audiogenic seizures is original and agree with and extend previous immunohistochemical for glur2 data obtained in the chinese p77pmc audiogenic rat strain, reinforcing the association of limbic ampa alterations with epileptic seizures. |
2010-03-09 |
2023-08-12 |
rat |
| Thor S Thorsen, Kenneth L Madsen, Nelson Rebola, Mette Rathje, Victor Anggono, Anders Bach, Irina S Moreira, Nicolai Stuhr-Hansen, Tino Dyhring, Dan Peters, Thijs Beuming, Richard Huganir, Harel Weinstein, Christophe Mulle, Kristian Strømgaard, Lars Christian B Rønn, Ulrik Gethe. Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 1. 2010-03-09. PMID:20018661. |
pretreatment of cultured hippocampal neurons with fsc231 inhibited coimmunopreciptation of the ampa receptor glur2 subunit with pick1. |
2010-03-09 |
2023-08-12 |
Not clear |
| Christian M Cremer, Markus Cremer, Jennifer Lopez Escobar, Erwin-J Speckmann, Karl Zille. Fast, quantitative in situ hybridization of rare mRNAs using 14C-standards and phosphorus imaging. Journal of neuroscience methods. vol 185. issue 1. 2010-02-26. PMID:19761793. |
we used this approach as an example for applications to quantify the expression of glur1 and glur2 subunit mrnas of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor in the hippocampus of untreated rats, and after intraperitoneal application of the organo-arsenic compound dimethyl arsenic acid. |
2010-02-26 |
2023-08-12 |
rat |
| Sohila Zadran, Qingyu Qin, Xiaoning Bi, Homera Zadran, Young Kim, Michael R Foy, Richard Thompson, Michel Baudr. 17-Beta-estradiol increases neuronal excitability through MAP kinase-induced calpain activation. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 51. 2010-02-18. PMID:19995977. |
furthermore, e2 treatment of acute hippocampal slices resulted in increased actin polymerization and membrane levels of glur1 but not glur2/3 subunits of ampa receptors; both effects were also blocked by a calpain inhibitor. |
2010-02-18 |
2023-08-12 |
Not clear |
| Ni Fan, Hongwei Yang, Jian Zhang, Chu Che. Reduced expression of glutamate receptors and phosphorylation of CREB are responsible for in vivo Delta9-THC exposure-impaired hippocampal synaptic plasticity. Journal of neurochemistry. vol 112. issue 3. 2010-02-16. PMID:19912468. |
chronic in vivo exposure to delta9-thc produced cb1r-dependent decreases in expression of hippocampal glur1, nr2a, and nr2b, the ratio of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (ampa)/nmda receptor-gated currents, and phosphorylation of creb. |
2010-02-16 |
2023-08-12 |
Not clear |
| K Sarantis, N Matsokis, F Angelato. Synergistic interactions of dopamine D1 and glutamate NMDA receptors in rat hippocampus and prefrontal cortex: involvement of ERK1/2 signaling. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19647050. |
in order to understand the molecular basis of dopamine/glutamate interactions in rat pfc and hippocampus, we investigated (a) the effect of in vitro dopamine d1 receptor stimulation on glutamate n-methyl-d-aspartate (nmda) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (ampa) receptor subunits' phosphorylation and (b) the signal transduction pathway underlying these interactions, by examining the involvement of d1-extracellular regulated kinase 1/2 (erk1/2) and d1/protein kinase a (pka)/dopamine- and cyclic amp-regulated phosphoprotein-32 (darpp-32) signaling pathways. |
2010-02-12 |
2023-08-12 |
rat |
| K Sarantis, N Matsokis, F Angelato. Synergistic interactions of dopamine D1 and glutamate NMDA receptors in rat hippocampus and prefrontal cortex: involvement of ERK1/2 signaling. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19647050. |
our results showed that stimulation of d1 receptor by the specific agonist skf38393 (10 microm) in pfc and hippocampal slices significantly increased the phosphorylation state of nr1ser897 and nr2bser1303 subunits of nmda receptor and of the glur1 (ser831 and ser845) subunit of ampa receptor, as well as of erk1/2, but not of darpp-32. |
2010-02-12 |
2023-08-12 |
rat |
| K Sarantis, N Matsokis, F Angelato. Synergistic interactions of dopamine D1 and glutamate NMDA receptors in rat hippocampus and prefrontal cortex: involvement of ERK1/2 signaling. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19647050. |
in conclusion, in pfc and hippocampus: (a) a strong synergistic interaction of d1 and nmda receptors exists, which results in a significant erk1/2 pathway activation, (b) the d1 and the d1/nmda receptor-induced phosphorylation of nmda and ampa receptor subunits seems to rely on erk1/2 signaling and could to some extent underlie the enhancement of nmda and ampa receptor currents mediated by d1 receptor activation. |
2010-02-12 |
2023-08-12 |
rat |
| C Geoffrey Lau, Yukihiro Takayasu, Alma Rodenas-Ruano, Ana V Paternain, Juan Lerma, Michael V L Bennett, R Suzanne Zuki. SNAP-25 is a target of protein kinase C phosphorylation critical to NMDA receptor trafficking. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 1. 2010-02-04. PMID:20053906. |
constitutively active pkc delivered via the patch pipette potentiated nmda (but not ampa) whole-cell currents in hippocampal neurons. |
2010-02-04 |
2023-08-12 |
Not clear |
| Ming Zhou, Lisa Conboy, Carmen Sandi, Marian Joëls, Harm J Kruger. Fear conditioning enhances spontaneous AMPA receptor-mediated synaptic transmission in mouse hippocampal CA1 area. The European journal of neuroscience. vol 30. issue 8. 2010-01-05. PMID:19811531. |
therefore, we examined whether fear conditioning is also accompanied by changes in ampa receptor-mediated synaptic transmission in the hippocampus. |
2010-01-05 |
2023-08-12 |
mouse |
| Peter R Moult, Jenni Harve. Regulation of glutamate receptor trafficking by leptin. Biochemical Society transactions. vol 37. issue Pt 6. 2010-01-05. PMID:19909277. |
recent studies have demonstrated that trafficking of ampa (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid) receptors is pivotal for activity-dependent hippocampal synaptic plasticity. |
2010-01-05 |
2023-08-12 |
Not clear |
| Xiaowei W Su, Xiao-Yuan Li, Mounira Banasr, Ja Wook Koo, Mohammed Shahid, Brian Henry, Ronald S Duma. Chronic treatment with AMPA receptor potentiator Org 26576 increases neuronal cell proliferation and survival in adult rodent hippocampus. Psychopharmacology. vol 206. issue 2. 2009-12-22. PMID:19603152. |
chronic treatment with ampa receptor potentiator org 26576 increases neuronal cell proliferation and survival in adult rodent hippocampus. |
2009-12-22 |
2023-08-12 |
Not clear |
| R Katoh-Semba, R Kaneko, S Kitajima, M Tsuzuki, S Ichisaka, Y Hata, H Yamada, N Miyazaki, Y Takahashi, K Kat. Activation of p38 mitogen-activated protein kinase is required for in vivo brain-derived neurotrophic factor production in the rat hippocampus. Neuroscience. vol 163. issue 1. 2009-12-15. PMID:19524026. |
in fact, kainic acid or ampa enhances bdnf levels in hippocampal granule neurons. |
2009-12-15 |
2023-08-12 |
rat |
| Michael Feyder, Lisa Wiedholz, Rolf Sprengel, Andrew Holme. Impaired associative fear learning in mice with complete loss or haploinsufficiency of AMPA GluR1 receptors. Frontiers in behavioral neuroscience. vol 1. 2009-12-14. PMID:18958186. |
ampa glur1 glutamate receptor knockout mice (ko) exhibit abnormal hippocampal and amygdala plasticity, and deficits on various assays for cognition including pavlovian fear conditioning. |
2009-12-14 |
2023-08-12 |
mouse |
| Hang Lin, Paul Higgins, Horace H Loh, Ping-Yee Law, Dezhi Lia. Bidirectional effects of fentanyl on dendritic spines and AMPA receptors depend upon the internalization of mu opioid receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 9. 2009-12-07. PMID:19295508. |
as changes in dendritic spines and synaptic ampa receptors play important roles in addiction and memory loss, we investigated how fentanyl affects dendritic spines and synaptic ampa receptors in cultured hippocampal neurons. |
2009-12-07 |
2023-08-12 |
Not clear |
| Jason M Uslaner, Sophie Parmentier-Batteur, Rosemarie B Flick, Nathaniel O Surles, June S H Lam, Caitlyn H McNaughton, Marlene A Jacobson, Pete H Hutso. Dose-dependent effect of CDPPB, the mGluR5 positive allosteric modulator, on recognition memory is associated with GluR1 and CREB phosphorylation in the prefrontal cortex and hippocampus. Neuropharmacology. vol 57. issue 5-6. 2009-12-04. PMID:19627999. |
we then examined the effects of cdppb (0, 3, 10, or 30 mg/kg) on markers of synaptic plasticity in prefrontal cortex and hippocampus, focusing on the expression and phosphorylation status of proteins involved in nmda related signaling, including the nmda receptor subunits nr1 and nr2b, the ampa receptor subunit glur1, alphaca((2+))/cam dependent ser-thr kinases ii (alphacamkii), and the transcription factor creb. |
2009-12-04 |
2023-08-12 |
rat |
| Takahiro Yaguchi, Tetsu Nagata, Tomoyuki Nishizak. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine improves cognitive decline by enhancing long-term depression. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19482045. |
1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (pophtcho) (1 microm) enhanced long-term depression (ltd), a synaptic plasticity relevant to learning and memory, in the ca1 region of rat hippocampal slices, where expression of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (ampa) receptor subunit glur1 on the plasma membrane was decreased. |
2009-12-01 |
2023-08-12 |
rat |
| Justin T Rogers, Edwin J Weebe. Reelin and apoE actions on signal transduction, synaptic function and memory formation. Neuron glia biology. vol 4. issue 3. 2009-11-16. PMID:19674510. |
notably, reelin and apoe have been shown to modulate hippocampal long-term potentiation in general, and affect nmda receptor and ampa receptor regulation specifically. |
2009-11-16 |
2023-08-12 |
mouse |