| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jennifer Coles, Sowmini K Oomman, William M Henne, Richard M Bliss, Trenton C Hoffman, VelvetLee Finckbone, Howard Strahlendorf, Jean Strahlendor. AMPA-induced dark cell degeneration is associated with activation of caspases in pyramidal neurons of the rat hippocampus. Neuroscience letters. vol 436. issue 3. 2008-08-25. PMID:18417289. |
immunohistochemical analyses revealed that immunoreactivity of the active form of caspase-9 and -3 was increased in pyramidal neurons in ca1 and ca3 regions of the hippocampus following ampa (100 microm). |
2008-08-25 |
2023-08-12 |
rat |
| Julia Vaglenova, Noemi Pandiella, Nayana Wijayawardhane, Tiru Vaithianathan, Sandjay Birru, Charles Breese, Vishnu Suppiramaniam, Clark Randa. Aniracetam reversed learning and memory deficits following prenatal ethanol exposure by modulating functions of synaptic AMPA receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 5. 2008-08-01. PMID:17609677. |
cognitive disabilities, monitored in adult rats by a two-way active avoidance task, correlated well with a significant reduction of ampa (alpha-amino-3 hydro-5 methyl-isoxazole propionic acid) receptor-mediated miniature excitatory postsynaptic responses (mepscs) in the hippocampus. |
2008-08-01 |
2023-08-12 |
rat |
| Julia Vaglenova, Noemi Pandiella, Nayana Wijayawardhane, Tiru Vaithianathan, Sandjay Birru, Charles Breese, Vishnu Suppiramaniam, Clark Randa. Aniracetam reversed learning and memory deficits following prenatal ethanol exposure by modulating functions of synaptic AMPA receptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 5. 2008-08-01. PMID:17609677. |
after the termination of the nootropic treatment, a significant increase in both amplitude and frequency of ampa receptor-mediated mepscs in hippocampal ca-1 pyramidal cells was observed. |
2008-08-01 |
2023-08-12 |
rat |
| Fleur Margaret Howells, Vivienne Ann Russel. Glutamate-stimulated release of norepinephrine in hippocampal slices of animal models of attention-deficit/hyperactivity disorder (spontaneously hypertensive rat) and depression/anxiety-like behaviours (Wistar-Kyoto rat). Brain research. vol 1200. 2008-07-18. PMID:18295191. |
(3) exposure of hippocampal slices to a second and third 1-min pulse of glutamate revealed significant decreases in the peaks of [(3)h]norepinephrine release suggesting internalization of ampa receptors. |
2008-07-18 |
2023-08-12 |
rat |
| Fleur Margaret Howells, Vivienne Ann Russel. Glutamate-stimulated release of norepinephrine in hippocampal slices of animal models of attention-deficit/hyperactivity disorder (spontaneously hypertensive rat) and depression/anxiety-like behaviours (Wistar-Kyoto rat). Brain research. vol 1200. 2008-07-18. PMID:18295191. |
this effect was blocked by cnqx, suggesting that ampa receptors were required for the nmda effect and that there was an nmda component of ampa receptor internalization in shr hippocampus which was not evident in wky. |
2008-07-18 |
2023-08-12 |
rat |
| Fleur Margaret Howells, Vivienne Ann Russel. Glutamate-stimulated release of norepinephrine in hippocampal slices of animal models of attention-deficit/hyperactivity disorder (spontaneously hypertensive rat) and depression/anxiety-like behaviours (Wistar-Kyoto rat). Brain research. vol 1200. 2008-07-18. PMID:18295191. |
the present findings reveal a novel nmda component that influences ampa receptor-mediated regulation of norepinephrine release in shr hippocampus. |
2008-07-18 |
2023-08-12 |
rat |
| Fuyuki Mitsuyama, Gen Niimi, Kunio Kato, Kazushige Hirosawa, Katsuhiko Mikoshiba, Masato Okuya, Kostadin Karagiozov, Yoko Kato, Tetsuo Kanno, Hirotoshi Sanoe, Tadashi Koid. Redistribution of microtubules in dendrites of hippocampal CA1 neurons after tetanic stimulation during long-term potentiation. Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia. vol 113. issue 1. 2008-07-10. PMID:18491451. |
it is now well accepted that the trafficking of ampa receptors to the postsynaptic plasma membrane plays an essential role in long-term potentiation at the hippocampal schaffer collateral synapses on ca1 pyramidal cells, but the motor mechanism of trafficking is unknown. |
2008-07-10 |
2023-08-12 |
rat |
| C J Peddie, H A Davies, F M Colyer, M G Stewart, J J Rodrígue. Colocalisation of serotonin2A receptors with the glutamate receptor subunits NR1 and GluR2 in the dentate gyrus: an ultrastructural study of a modulatory role. Experimental neurology. vol 211. issue 2. 2008-07-07. PMID:18439999. |
here, we have conducted an electron microscopic examination of 5-ht(2a)r distribution with the glutamate n-methyl-d-aspartate (nmda) and amino-3-hydroxy-5-methyl-4-isoxazoleproprionic acid (ampa) receptor subunits nr1 and glur2 in the hippocampal dentate gyrus (dg) in order to investigate whether 5-ht(2a)r location is compatible with a modulatory role over nmda and/or ampa receptor mediated neurotransmission. |
2008-07-07 |
2023-08-12 |
Not clear |
| S Xapelli, L Bernardino, R Ferreira, S Grade, A P Silva, J R Salgado, C Cavadas, E Grouzmann, F R Poulsen, B Jakobsen, C R Oliveira, J Zimmer, J O Malv. Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia. The European journal of neuroscience. vol 27. issue 8. 2008-07-01. PMID:18412629. |
the neuroprotective effect of neuropeptide y (npy) receptor activation was investigated in organotypic mouse hippocampal slice cultures exposed to the glutamate receptor agonist alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa). |
2008-07-01 |
2023-08-12 |
mouse |
| Susana S Correia, Silvia Bassani, Tyler C Brown, Marie-France Lisé, Donald S Backos, Alaa El-Husseini, Maria Passafaro, José A Esteba. Motor protein-dependent transport of AMPA receptors into spines during long-term potentiation. Nature neuroscience. vol 11. issue 4. 2008-06-11. PMID:18311135. |
we found that, in rat hippocampus, the insertion of ampa receptors (ampars) into spines during synaptic plasticity requires a specific motor protein, which we identified as myosin va. we found that myosin va associates with ampars through its cargo binding domain. |
2008-06-11 |
2023-08-12 |
rat |
| M Morissette, M Le Saux, M D'Astous, S Jourdain, S Al Sweidi, N Morin, E Estrada-Camarena, Pablo Mendez, Luis Miguel Garcia-Segura, T Di Paol. Contribution of estrogen receptors alpha and beta to the effects of estradiol in the brain. The Journal of steroid biochemistry and molecular biology. vol 108. issue 3-5. 2008-06-02. PMID:17936613. |
the eralpha agonist, ppt, is shown as estradiol to modulate hippocampal nmda receptors and ampa receptors in cortex and striatum of ovariectomized rats whereas the erbeta agonist dpn is inactive. |
2008-06-02 |
2023-08-12 |
mouse |
| Vladyslav V Vyazovskiy, Chiara Cirelli, Martha Pfister-Genskow, Ugo Faraguna, Giulio Tonon. Molecular and electrophysiological evidence for net synaptic potentiation in wake and depression in sleep. Nature neuroscience. vol 11. issue 2. 2008-05-08. PMID:18204445. |
we show that, in rat cortex and hippocampus, glur1-containing ampa receptor (ampar) levels are high during wakefulness and low during sleep, and changes in the phosphorylation states of ampars, camkii and gsk3beta are consistent with synaptic potentiation during wakefulness and depression during sleep. |
2008-05-08 |
2023-08-12 |
rat |
| André R Gomes, Joana S Ferreira, Ana V Paternain, Juan Lerma, Carlos B Duarte, Ana Luísa Carvalh. Characterization of alternatively spliced isoforms of AMPA receptor subunits encoding truncated receptors. Molecular and cellular neurosciences. vol 37. issue 2. 2008-04-25. PMID:18065236. |
we identified transcripts for alternatively spliced isoforms of ampa receptor subunits which lack both the flip and the flop exons, in hippocampal and retinal cultures. |
2008-04-25 |
2023-08-12 |
rat |
| Lin Xu, Nicholas Rensing, Xiao-Feng Yang, Hai Xia Zhang, Liu Lin Thio, Steven M Rothman, Aryan E Weisenfeld, Michael Wong, Kelvin A Yamad. Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. The Journal of clinical investigation. vol 118. issue 1. 2008-04-14. PMID:18097472. |
leptin inhibited alpha-amino-3-hydroxy-5-methyl-4-isoxazole proprionic acid (ampa) receptor-mediated synaptic transmission in mouse hippocampal slices but failed to inhibit synaptic responses in slices from leptin receptor-deficient db/db mice. |
2008-04-14 |
2023-08-12 |
mouse |
| Dmitri Leonoudakis, Pingwei Zhao, Eric C Beatti. Rapid tumor necrosis factor alpha-induced exocytosis of glutamate receptor 2-lacking AMPA receptors to extrasynaptic plasma membrane potentiates excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 9. 2008-04-08. PMID:18305246. |
our previous studies show that a major component of this response, the inflammatory cytokine tumor necrosis factor alpha (tnfalpha), causes a rapid increase in ampa glutamate receptors (ampars) on the plasma membrane of cultured hippocampal neurons. |
2008-04-08 |
2023-08-12 |
Not clear |
| Shinji Matsuda, Eriko Miura, Keiko Matsuda, Wataru Kakegawa, Kazuhisa Kohda, Masahiko Watanabe, Michisuke Yuzak. Accumulation of AMPA receptors in autophagosomes in neuronal axons lacking adaptor protein AP-4. Neuron. vol 57. issue 5. 2008-04-08. PMID:18341993. |
here, we show that disruption of the gene encoding the beta subunit of ap-4 resulted in increased accumulation of axonal autophagosomes, which contained ampa receptors and transmembrane ampa receptor regulatory proteins (tarps), in axons of hippocampal neurons and cerebellar purkinje cells both in vitro and in vivo. |
2008-04-08 |
2023-08-12 |
Not clear |
| Kentaro Matsuzaki, Kenichi Miyazaki, Seiichiro Sakai, Hiromu Yawo, Norihito Nakata, Shigeki Moriguchi, Kohji Fukunaga, Akihito Yokosuka, Yutaka Sashida, Yoshihiro Mimaki, Tohru Yamakuni, Yasushi Ohizum. Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. European journal of pharmacology. vol 578. issue 2-3. 2008-04-03. PMID:17976577. |
nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase a-mediated phosphorylation of the ampa receptor subunit, glur1, and the postsynaptic receptor response to glutamate in murine hippocampus. |
2008-04-03 |
2023-08-12 |
Not clear |
| Kentaro Matsuzaki, Kenichi Miyazaki, Seiichiro Sakai, Hiromu Yawo, Norihito Nakata, Shigeki Moriguchi, Kohji Fukunaga, Akihito Yokosuka, Yutaka Sashida, Yoshihiro Mimaki, Tohru Yamakuni, Yasushi Ohizum. Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. European journal of pharmacology. vol 578. issue 2-3. 2008-04-03. PMID:17976577. |
in the present study, using combined methods of biochemistry and electrophysiology, we examined the effects of nobiletin on phosphorylation of glur1 receptor, the subunit of alpha-amino-3-hydroxy-5-methyl-d-aspartate (ampa) receptors, and the receptor-mediated synaptic transmission in the hippocampus, a region implicated in memory formation, in culture and/or in slices. |
2008-04-03 |
2023-08-12 |
Not clear |
| Kentaro Matsuzaki, Kenichi Miyazaki, Seiichiro Sakai, Hiromu Yawo, Norihito Nakata, Shigeki Moriguchi, Kohji Fukunaga, Akihito Yokosuka, Yutaka Sashida, Yoshihiro Mimaki, Tohru Yamakuni, Yasushi Ohizum. Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. European journal of pharmacology. vol 578. issue 2-3. 2008-04-03. PMID:17976577. |
furthermore, our electrophysiological analysis showed that nobiletin potentiated the ampa receptor-mediated synaptic transmission at schaffer collateral-ca1 pyramidal cell synapses in the hippocampal slices. |
2008-04-03 |
2023-08-12 |
Not clear |
| Kentaro Matsuzaki, Kenichi Miyazaki, Seiichiro Sakai, Hiromu Yawo, Norihito Nakata, Shigeki Moriguchi, Kohji Fukunaga, Akihito Yokosuka, Yutaka Sashida, Yoshihiro Mimaki, Tohru Yamakuni, Yasushi Ohizum. Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. European journal of pharmacology. vol 578. issue 2-3. 2008-04-03. PMID:17976577. |
these findings suggest that nobiletin probably up-regulates synaptic transmission via the postsynaptic ampa receptors at least partially by stimulation of pka-mediated phosphorylation of glur1 receptor in the hippocampus. |
2008-04-03 |
2023-08-12 |
Not clear |