| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mi Yang, Chang-Hao Luo, Ying-Qi Zhu, Yuan-Chu Liu, Ye-Juan An, Javed Iqbal, Zhe-Zhi Wang, Xin-Ming M. 7, 8-Dihydroxy-4-methylcoumarin reverses depression model-induced depression-like behaviors and alteration of dendritic spines in the mood circuits. Psychoneuroendocrinology. vol 119. 2021-07-21. PMID:32563935. |
our results showed that cums-induced depression-like behaviors were accompanied by a decrease in spine density in pyramidal neurons of both the hippocampal ca3 area and the mpfc, and an increase in spine density in both the neurons of bla and the medium spiny neurons (msns) of the nac, as well as a decrease in the levels of the ampa receptor subunit glua1 and kalirin-7 in the hippocampus compared with the control group. |
2021-07-21 |
2023-08-13 |
rat |
| Anna A Kovalenko, Maria V Zakharova, Olga E Zubareva, Alexander P Schwarz, Tatiana Y Postnikova, Aleksey V Zaitse. Alterations in mRNA and Protein Expression of Glutamate Receptor Subunits Following Pentylenetetrazole-induced Acute Seizures in Young Rats. Neuroscience. vol 468. 2021-07-21. PMID:34102267. |
in the present study, we analyzed changes in the expression of nmda and ampa receptor subunits in the different brain regions (dorsal hippocampus, amygdala, and the medial prefrontal, temporal, and entorhinal cortex) using a pentylenetetrazole (ptz) model of seizures in 3-week-old rats. |
2021-07-21 |
2023-08-13 |
rat |
| Veronika A Nikitina, Maria V Zakharova, Alexander N Trofimov, Alexander P Schwarz, Gleb V Beznin, Sergei G Tsikunov, Olga E Zubarev. Neonatal Exposure to Bacterial Lipopolysaccharide Affects Behavior and Expression of Ionotropic Glutamate Receptors in the Hippocampus of Adult Rats after Psychogenic Trauma. Biochemistry. Biokhimiia. vol 86. issue 6. 2021-07-15. PMID:34225597. |
here, we studied expression of nmda (glun1, glun2a, glun2b) and ampa (glua1, glua2) glutamate receptor subunits, as well as glutamate transporter eaat2, in the ventral and dorsal regions of the hippocampus of rats injected with lps during the third postnatal week and then subjected to predator stress (contact with a python) in adulthood. |
2021-07-15 |
2023-08-13 |
rat |
| Petra Mazzocchetti, Andrea Mancini, Miriam Sciaccaluga, Alfredo Megaro, Laura Bellingacci, Massimiliano Di Filippo, Elena Nardi Cesarini, Michele Romoli, Nicolò Carrano, Fabrizio Gardoni, Alessandro Tozzi, Paolo Calabresi, Cinzia Cost. Low doses of Perampanel protect striatal and hippocampal neurons against in vitro ischemia by reversing the ischemia-induced alteration of AMPA receptor subunit composition. Neurobiology of disease. vol 140. 2021-07-08. PMID:32222474. |
low doses of perampanel protect striatal and hippocampal neurons against in vitro ischemia by reversing the ischemia-induced alteration of ampa receptor subunit composition. |
2021-07-08 |
2023-08-13 |
rat |
| Alexandra Marsillo, Lovena David, Bishoy Gerges, Daniel Kerr, Rodina Sadek, Vitaliy Lasiychuk, David Salame, Youstina Soliman, Silvia Menkes, Aheli Chatterjee, Andrew Mancuso, Probal Banerje. PKC epsilon as a neonatal target to correct FXS-linked AMPA receptor translocation in the hippocampus, boost PVN oxytocin expression, and normalize adult behavior in Fmr1 knockout mice. Biochimica et biophysica acta. Molecular basis of disease. vol 1867. issue 4. 2021-07-02. PMID:33359697. |
pkc epsilon as a neonatal target to correct fxs-linked ampa receptor translocation in the hippocampus, boost pvn oxytocin expression, and normalize adult behavior in fmr1 knockout mice. |
2021-07-02 |
2023-08-13 |
mouse |
| Fatou Amar, Carlo Corona, Johanna Husson, Jin Liu, Michael Shelanski, Lloyd Green. Rapid ATF4 Depletion Resets Synaptic Responsiveness after cLTP. eNeuro. vol 8. issue 3. 2021-07-02. PMID:33980608. |
we evaluated the role of atf4 in mature hippocampal cultures subjected to a brief chemically induced ltp (cltp) protocol that results in changes in mepsc properties and synaptic ampa receptor density 1 h later, with return to baseline by 24 h. we find that atf4 protein, but not its mrna, is rapidly depleted by ∼50% in response to cltp induction via nmda receptor activation. |
2021-07-02 |
2023-08-13 |
human |
| Aoi Jitsuki-Takahashi, Susumu Jitsuki, Naoya Yamashita, Meiko Kawamura, Manabu Abe, Kenji Sakimura, Akane Sano, Fumio Nakamura, Yoshio Goshima, Takuya Takahash. Activity-induced secretion of semaphorin 3A mediates learning. The European journal of neuroscience. vol 53. issue 10. 2021-06-30. PMID:33772906. |
furthermore, the secreted semaphorin 3a in the hippocampus mediated contextual memory formation likely by driving ampa receptors into hippocampal synapses via the neuropilin1-plexin a4-semaphorin receptor complex. |
2021-06-30 |
2023-08-13 |
Not clear |
| Stefan Hardt, Dario Tascio, Stefan Passlick, Aline Timmermann, Ronald Jabs, Christian Steinhäuser, Gerald Seifer. Auxiliary Subunits Control Function and Subcellular Distribution of AMPA Receptor Complexes in NG2 Glia of the Developing Hippocampus. Frontiers in cellular neuroscience. vol 15. 2021-06-29. PMID:34177466. |
auxiliary subunits control function and subcellular distribution of ampa receptor complexes in ng2 glia of the developing hippocampus. |
2021-06-29 |
2023-08-13 |
Not clear |
| Stefan Hardt, Dario Tascio, Stefan Passlick, Aline Timmermann, Ronald Jabs, Christian Steinhäuser, Gerald Seifer. Auxiliary Subunits Control Function and Subcellular Distribution of AMPA Receptor Complexes in NG2 Glia of the Developing Hippocampus. Frontiers in cellular neuroscience. vol 15. 2021-06-29. PMID:34177466. |
early in postnatal development, hippocampal ng2 glia express ampa receptors with a significant ca |
2021-06-29 |
2023-08-13 |
Not clear |
| Marion Bonneau, Shane T O' Sullivan, Miguel A Gonzalez-Lozano, Paul Baxter, Phillippe Gautier, Elena Marchisella, Neil R Hardingham, Robert A Chesters, Helen Torrance, David M Howard, Maurits A Jansen, Melanie McMillan, Yasmin Singh, Michel Didier, Frank Koopmans, Colin A Semple, Andrew M McIntosh, Hansjürgen Volkmer, Maarten Loos, Kevin Fox, Giles E Hardingham, Anthony C Vernon, David J Porteous, August B Smit, David J Price, J Kirsty Milla. Functional brain defects in a mouse model of a chromosomal t(1;11) translocation that disrupts DISC1 and confers increased risk of psychiatric illness. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33608504. |
synaptosome proteomics confirmed that the der1 mutation impacts synapse composition, and electrophysiology found reduced ampa:nmda ratio in hippocampal neurons, indicating changed excitatory signalling. |
2021-06-28 |
2023-08-13 |
mouse |
| Hiroki Yasuda, Hikaru Yamamoto, Kenji Hanamura, Mona Mehruba, Toshio Kawamata, Hiromi Morisaki, Masaaki Miyamoto, Shinji Takada, Tomoaki Shirao, Yoshitaka Ono, Hideyuki Muka. PKN1 promotes synapse maturation by inhibiting mGluR-dependent silencing through neuronal glutamate transporter activation. Communications biology. vol 3. issue 1. 2021-06-25. PMID:33244074. |
knocking out pkn1a, the dominant pkn1 subtype in the brain, unmasked abnormal input-nonspecific mglur-dependent long-term depression (mglur-ltd) and ampa receptor (ampar) silencing in the developing hippocampus. |
2021-06-25 |
2023-08-13 |
mouse |
| Kyle J Brymer, Jenessa Johnston, Justin J Botterill, Raquel Romay-Tallon, Milann A Mitchell, Josh Allen, Graziano Pinna, Hector J Caruncho, Lisa E Kalynchu. Fast-acting antidepressant-like effects of Reelin evaluated in the repeated-corticosterone chronic stress paradigm. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 10. 2021-06-23. PMID:31926481. |
injection of the ampa antagonist cnqx blocked the rescue of the behavioral phenotype by reelin but did completely block the effects of reelin on hippocampal neurogenesis. |
2021-06-23 |
2023-08-13 |
rat |
| Ban-Yu Saitoh, Eizo Tanaka, Norio Yamamoto, Daan van Kruining, Kyoko Iinuma, Yuko Nakamuta, Hiroo Yamaguchi, Ryo Yamasaki, Koichiro Matsumoto, Jun-Ichi Kir. Early postnatal allergic airway inflammation induces dystrophic microglia leading to excitatory postsynaptic surplus and autism-like behavior. Brain, behavior, and immunity. vol 95. 2021-06-23. PMID:33862170. |
immunoblotting using hippocampal tissues demonstrated that amounts of psd95, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor 2, and n-methyl-d-aspartate (nmda) receptor 2b were significantly increased in the ova group compared with the control group on p70, and a similar increasing trend for psd95 was observed on p30. |
2021-06-23 |
2023-08-13 |
mouse |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
d-lys-3-ghrp-6 impairs memory consolidation and downregulates the hippocampal serotonin ht1a, ht7 receptors and glutamate glua1 subunit of ampa receptors. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
we aimed to evaluate the effect of intracerebral injection of a ghrelin receptor antagonist (d-lys-3-ghrp-6) on memory consolidation in the inhibitory avoidance task and on the gene expression levels of serotonin ht1a and ht7 receptors, glutamate glun1 subunit of the nmda and glua1 subunit of the ampa receptors and calcium/calmodulin kinase ii-α in the hippocampus of rats. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
meanwhile, it led to a significant downregulation of the mrna expression levels of the hippocampal serotonin ht1a and ht7 receptors and glutamate glua1 subunit of the ampa receptors, but could not affect that of glun1 subunit of the nmda receptors and camkii-α. |
2021-06-21 |
2023-08-13 |
rat |
| Siamak Beheshti, Mitra Sami, Atefeh Mirzabeh, Azadeh Yazd. D-Lys-3-GHRP-6 impairs memory consolidation and downregulates the hippocampal serotonin HT1A, HT7 receptors and glutamate GluA1 subunit of AMPA receptors. Physiology & behavior. vol 223. 2021-06-21. PMID:32454141. |
it seems that part of the impairing effect of d-lys-3-ghrp-6 on inhibitory avoidance memory consolidation might be due to a decrease in the expression of serotonin ht1a and ht7 receptors and glutamate ampa receptors in the hippocampus of rats. |
2021-06-21 |
2023-08-13 |
rat |
| Zeinab Momeni, Maricris Bautista, Joseph Neapetung, Rylan Urban, Yasuhiko Yamamoto, Anand Krishnan, Verónica A Campanucc. RAGE signaling is required for AMPA receptor dysfunction in the hippocampus of hyperglycemic mice. Physiology & behavior. vol 229. 2021-06-21. PMID:33221393. |
rage signaling is required for ampa receptor dysfunction in the hippocampus of hyperglycemic mice. |
2021-06-21 |
2023-08-13 |
mouse |
| Leonardo Santana Novaes, Letícia Morais Bueno-de-Camargo, Carolina Demarchi Munho. Environmental enrichment prevents the late effect of acute stress-induced fear extinction deficit: the role of hippocampal AMPA-GluA1 phosphorylation. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33414437. |
additionally, we observed that ee prevented the stress-induced increase in ampa receptor glua1 subunit phosphorylation in the hippocampus, but not in the basolateral amygdala complex and the frontal cortex, indicating a potential mechanism by which it exerts its protective effect against the stress-induced behavioral outcome. |
2021-06-18 |
2023-08-13 |
rat |
| Luis A Trujillo-Villarreal, Viktor J Romero-Díaz, Iván Alberto Marino-Martínez, Lizeth Fuentes-Mera, Marco Antonio Ponce-Camacho, Gabriel A Devenyi, M Mallar Chakravarty, Alberto Camacho-Morales, Eduardo E Garza-Villarrea. Maternal cafeteria diet exposure primes depression-like behavior in the offspring evoking lower brain volume related to changes in synaptic terminals and gliosis. Translational psychiatry. vol 11. issue 1. 2021-06-18. PMID:33446642. |
also, offspring exhibited increase of the glur1 and glur2 subunits of ampa receptor, whereas a decrease in the mglur2 expression in hippocampus. |
2021-06-18 |
2023-08-13 |
rat |