| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M B Viana, R S Martins, M S C F Silva, S Xapelli, S H Vaz, A M Sebastiã. Deep Brain Stimulation of the dorsal raphe abolishes serotonin 1A facilitation of AMPA receptor-mediated synaptic currents in the ventral hippocampus. Behavioural brain research. vol 403. 2021-06-18. PMID:33476685. |
deep brain stimulation of the dorsal raphe abolishes serotonin 1a facilitation of ampa receptor-mediated synaptic currents in the ventral hippocampus. |
2021-06-18 |
2023-08-13 |
rat |
| Luisa Ponzoni, Daniela Braida, Lucia Carboni, Milena Moretti, Paola Viani, Francesco Clementi, Michele Zoli, Cecilia Gotti, Mariaelvina Sal. Persistent cognitive and affective alterations at late withdrawal stages after long-term intermittent exposure to tobacco smoke or electronic cigarette vapour: Behavioural changes and their neurochemical correlates. Pharmacological research. vol 158. 2021-06-03. PMID:32450347. |
at hippocampal level, the withdrawal-induced changes in the levels of ampa receptor glua1 and glua2/3 subunits, psd 95 protein, corticotropin-releasing factor (crf) and crf receptor 1 (crfr1) mrna were biphasic: ampa receptor subunit and psd95 protein levels initially remained unchanged and decreased after 60-90 days, whereas crf/crfr1 mrna levels initially increased and then markedly decreased after 60 days. |
2021-06-03 |
2023-08-13 |
mouse |
| Daniela Monteiro-Fernandes, Joana Margarida Silva, Carina Soares-Cunha, Christina Dalla, Nikolaos Kokras, François Arnaud, Rodolphe Billiras, Viktoriya Zhuravleva, Clarissa Waites, Sylvie Bretin, Nuno Sousa, Ioannis Sotiropoulo. Allosteric modulation of AMPA receptors counteracts Tau-related excitotoxic synaptic signaling and memory deficits in stress- and Aβ-evoked hippocampal pathology. Molecular psychiatry. 2021-05-28. PMID:32467647. |
allosteric modulation of ampa receptors counteracts tau-related excitotoxic synaptic signaling and memory deficits in stress- and aβ-evoked hippocampal pathology. |
2021-05-28 |
2023-08-13 |
Not clear |
| Daniela Monteiro-Fernandes, Joana Margarida Silva, Carina Soares-Cunha, Christina Dalla, Nikolaos Kokras, François Arnaud, Rodolphe Billiras, Viktoriya Zhuravleva, Clarissa Waites, Sylvie Bretin, Nuno Sousa, Ioannis Sotiropoulo. Allosteric modulation of AMPA receptors counteracts Tau-related excitotoxic synaptic signaling and memory deficits in stress- and Aβ-evoked hippocampal pathology. Molecular psychiatry. 2021-05-28. PMID:32467647. |
our findings suggest that positive allosteric modulation of ampa receptors restores synaptic integrity and cognitive performance in stress- and aβ-evoked hippocampal pathology. |
2021-05-28 |
2023-08-13 |
Not clear |
| Jianmin Yang, Qian Ma, Iva Dincheva, Joanna Giza, Deqiang Jing, Tina Marinic, Teresa A Milner, Anjali Rajadhyaksha, Francis S Lee, Barbara L Hempstea. SorCS2 is required for social memory and trafficking of the NMDA receptor. Molecular psychiatry. vol 26. issue 3. 2021-05-14. PMID:31988435. |
we have discovered that sorcs2 is a selective regulator of nmda receptor surface trafficking in hippocampal neurons, without altering ampa receptor trafficking. |
2021-05-14 |
2023-08-13 |
mouse |
| Paw-Min-Thein-Oo, Yuya Sakimoto, Hiroyuki Kida, Dai Mitsushim. Proximodistal Heterogeneity in Learning-promoted Pathway-specific Plasticity at Dorsal CA1 Synapses. Neuroscience. vol 437. 2021-05-14. PMID:32360699. |
contextual learning requires the delivery of ampa receptors to ca1 synapses in the dorsal hippocampus. |
2021-05-14 |
2023-08-13 |
rat |
| Michael R Chojnacki, Subramaniam Jayanthi, Jean Lud Cade. Methamphetamine pre-exposure induces steeper escalation of methamphetamine self-administration with consequent alterations in hippocampal glutamate AMPA receptor mRNAs. European journal of pharmacology. vol 889. 2021-05-10. PMID:33220277. |
methamphetamine pre-exposure induces steeper escalation of methamphetamine self-administration with consequent alterations in hippocampal glutamate ampa receptor mrnas. |
2021-05-10 |
2023-08-13 |
human |
| Patrick Szu-Ying Yen, Yen-Chin Liu, Chun-Hsien Chu, Shiou-Lan Che. Upregulation of Glutamatergic Receptors in Hippocampus and Locomotor Hyperactivity in Aged Spontaneous Hypertensive Rat. Cellular and molecular neurobiology. 2021-05-06. PMID:33954807. |
in the analysis of synaptic membrane protein, the expression of glutamatergic receptors, such as the n-methyl-d-aspartate (nmda) receptor receptors subunits 2b (glun2b) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptor 1 (glua1) in the hippocampus of shr were significantly higher than those of wky rats. |
2021-05-06 |
2023-08-13 |
rat |
| Jimin Yu, Eunbi Cho, Huiyoung Kwon, Jieun Jeon, Jae Seong Sin, Jun Kwon Park, Ji-Su Kim, Ji Woong Choi, Se Jin Park, Mira Jun, Young Choon Lee, Jong Hoon Ryu, Jeongwon Lee, Minho Moon, Seungheon Lee, Jong Hyun Cho, Dong Hyun Ki. Akt and calcium-permeable AMPA receptor are involved in the effect of pinoresinol on amyloid β-induced synaptic plasticity and memory deficits. Biochemical pharmacology. vol 184. 2021-04-22. PMID:33310049. |
pinoresinol enhanced hippocampal long-term potentiation (ltp) through calcium-permeable ampa receptor, which was mediated by akt activation. |
2021-04-22 |
2023-08-13 |
mouse |
| Pietro Micheli, Rui Ribeiro, Alejandro Giorgett. A Mechanistic Model of NMDA and AMPA Receptor-Mediated Synaptic Transmission in Individual Hippocampal CA3-CA1 Synapses: A Computational Multiscale Approach. International journal of molecular sciences. vol 22. issue 4. 2021-04-19. PMID:33546429. |
a mechanistic model of nmda and ampa receptor-mediated synaptic transmission in individual hippocampal ca3-ca1 synapses: a computational multiscale approach. |
2021-04-19 |
2023-08-13 |
Not clear |
| Lindsay M Achzet, Clara J Davison, Moira Shea, Isabella Sturgeon, Darrell A Jackso. Oxidative Stress Underlies the Ischemia/Reperfusion-Induced Internalization and Degradation of AMPA Receptors. International journal of molecular sciences. vol 22. issue 2. 2021-04-12. PMID:33450848. |
the hippocampus is particularly susceptible to ampa receptor-mediated delayed neuronal death as a result of ischemic/reperfusion injury. |
2021-04-12 |
2023-08-13 |
Not clear |
| João Pedro Costa-Nunes, Anna Gorlova, Dmitrii Pavlov, Raymond Cespuglio, Anna Gorovaya, Andrei Proshin, Aleksei Umriukhin, Eugene D Ponomarev, Alan V Kalueff, Tatyana Strekalova, Careen A Schroete. Ultrasound stress compromises the correlates of emotional-like states and brain AMPAR expression in mice: effects of antioxidant and anti-inflammatory herbal treatment. Stress (Amsterdam, Netherlands). vol 23. issue 4. 2021-03-24. PMID:31900023. |
a 3-week ultrasound exposure increased scores of anxiety-like behaviors in the standard tests and altered hippocampal expression as well as internalization of ampa receptor subunits glua1-a3. |
2021-03-24 |
2023-08-13 |
mouse |
| Nikolay N Dygalo, Tatyana S Kalinina, Galina T Shishkin. Stress-induced expression pattern of glutamate signaling genes associated with anhedonia. Stress (Amsterdam, Netherlands). vol 23. issue 6. 2021-03-24. PMID:32814471. |
main features of the expression patterns include the decrease in mrna levels for ampa and nmda subunits in the midbrain and hippocampus that is consistent with the hypothesis that "monoamine (serotonin)-glutamate/gaba long neural circuit" involved in mood regulation. |
2021-03-24 |
2023-08-13 |
human |
| Célia Fourrier, Camille Kropp, Agnès Aubert, Julie Sauvant, Carole Vaysse, Jean-Michel Chardigny, Sophie Layé, Corinne Joffre, Nathalie Castano. Rapeseed oil fortified with micronutrients improves cognitive alterations associated with metabolic syndrome. Brain, behavior, and immunity. vol 84. 2021-03-12. PMID:31731013. |
it concomitantly changed subunit composition of glutamatergic ampa and nmda receptors in the hippocampus that has been shown to modulate synaptic function related to spatial memory. |
2021-03-12 |
2023-08-13 |
mouse |
| Elisabetta Gerace, Elisa Zianni, Elisa Landucci, Tania Scartabelli, Rolando Berlinguer Palmini, Daniela Iezzi, Flavio Moroni, Monica Di Luca, Guido Mannaioni, Fabrizio Gardoni, Domenico E Pellegrini-Giampietr. Differential mechanisms of tolerance induced by NMDA and 3,5-dihydroxyphenylglycine (DHPG) preconditioning. Journal of neurochemistry. vol 155. issue 6. 2021-03-02. PMID:32343420. |
we investigated the molecular events triggered by nmda and 3,5-dihydroxyphenylglycine (dhpg) preconditioning, that lead to neuroprotection against excitotoxic insults (ampa or oxygen and glucose deprivation) in rat organotypic hippocampal slices, with particular attention on glutamate receptors and on cannabinoid system. |
2021-03-02 |
2023-08-13 |
rat |
| Neda Valian, Marziyeh Sorayya, Sareh Asadi, Fatemeh Sherafati, Ali Ershad, Sara Savaheli, Abolhassan Ahmadian. Preconditioning by ultra-low dose of tramadol reduces the severity of tramadol-induced seizure: Contribution of glutamate receptors. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 133. 2021-02-24. PMID:33249277. |
the expression of norbin (as a regulator of metabotropic glutamate receptor 5), calponin3 (as a regulator of excitatory synaptic markers), nr1 (nmda receptor subunit 1) and glur1 (ampa receptor subunit 1) was measured in hippocampus, prefrontal cortex (pfc) and amygdala. |
2021-02-24 |
2023-08-13 |
rat |
| Ji-Eun Kim, Hana Park, Ji-Eun Lee, Tae-Hyun Kim, Tae-Cheon Kan. PTEN Is Required for The Anti-Epileptic Effects of AMPA Receptor Antagonists in Chronic Epileptic Rats. International journal of molecular sciences. vol 21. issue 16. 2021-02-18. PMID:32781725. |
in the present study, we found that ampar antagonists (perampanel and gyki 52466) decreased glutamate ionotropic receptor ampa type subunit 1 (gria1) surface expression in the epileptic rat hippocampus. |
2021-02-18 |
2023-08-13 |
rat |
| Luís F Ribeiro, Tatiana Catarino, Mário Carvalho, Luísa Cortes, Sandra D Santos, Patricio O Opazo, Lyn Rosenbrier Ribeiro, Bárbara Oliveiros, Daniel Choquet, José A Esteban, João Peça, Ana Luísa Carvalh. Ligand-independent activity of the ghrelin receptor modulates AMPA receptor trafficking and supports memory formation. Science signaling. vol 14. issue 670. 2021-02-17. PMID:33593997. |
blocking this activity produced a decrease in the synaptic content of ampa receptors in hippocampal neurons and a reduction in glua1 phosphorylation at ser |
2021-02-17 |
2023-08-13 |
Not clear |
| Elena Coccia, Laura Planells-Ferrer, Raquel Badillos-Rodríguez, Marta Pascual, Miguel F Segura, Rita Fernández-Hernández, Joaquin López-Soriano, Eloi Garí, Eduardo Soriano, Bruna Barneda-Zahonero, Rana S Moubarak, M Jose Pérez-García, Joan X Comell. SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L. Cell death & disease. vol 11. issue 2. 2021-02-16. PMID:32015347. |
this interaction also modulates non-apoptotic functions of caspases, such as the endocytosis of ampa receptor (ampar) in hippocampal long-term depression (ltd). |
2021-02-16 |
2023-08-13 |
Not clear |
| Alicia M Purkey, Mark L Dell'Acqu. Phosphorylation-Dependent Regulation of Ca Frontiers in synaptic neuroscience. vol 12. 2021-02-11. PMID:32292336. |
phosphorylation-dependent regulation of ca experience-dependent learning and memory require multiple forms of plasticity at hippocampal and cortical synapses that are regulated by n-methyl-d-aspartate receptors (nmda) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa)-type ionotropic glutamate receptors (nmdar, ampar). |
2021-02-11 |
2023-08-13 |
Not clear |