| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Camilla Bellone, Christian Lüsche. mGluRs induce a long-term depression in the ventral tegmental area that involves a switch of the subunit composition of AMPA receptors. The European journal of neuroscience. vol 21. issue 5. 2005-05-27. PMID:15813937. |
mglurs induce a long-term depression in the ventral tegmental area that involves a switch of the subunit composition of ampa receptors. |
2005-05-27 |
2023-08-12 |
rat |
| G C Harris, M Wimmer, R Byrne, G Aston-Jone. Glutamate-associated plasticity in the ventral tegmental area is necessary for conditioning environmental stimuli with morphine. Neuroscience. vol 129. issue 3. 2005-03-07. PMID:15541905. |
rats received bilateral microinjections of either the nmda antagonist ap5 (0.48 nmol/0.3 microl), the ampa antagonist cnqx (0.21 nmol/0.3 microl), or vehicle into the vta prior to each of three morphine-conditioning sessions. |
2005-03-07 |
2023-08-12 |
rat |
| G C Harris, M Wimmer, R Byrne, G Aston-Jone. Glutamate-associated plasticity in the ventral tegmental area is necessary for conditioning environmental stimuli with morphine. Neuroscience. vol 129. issue 3. 2005-03-07. PMID:15541905. |
both the ampa and nmda receptor antagonists blocked the development of morphine cpp when given into the vta but not when given outside the vta. |
2005-03-07 |
2023-08-12 |
rat |
| Satoshi Ikemoto, Brian M Witkin, Abraham Zangen, Roy A Wis. Rewarding effects of AMPA administration into the supramammillary or posterior hypothalamic nuclei but not the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 25. 2004-11-24. PMID:15215298. |
rewarding effects of ampa administration into the supramammillary or posterior hypothalamic nuclei but not the ventral tegmental area. |
2004-11-24 |
2023-08-12 |
rat |
| Satoshi Ikemoto, Brian M Witkin, Abraham Zangen, Roy A Wis. Rewarding effects of AMPA administration into the supramammillary or posterior hypothalamic nuclei but not the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 25. 2004-11-24. PMID:15215298. |
we examined whether injections of the excitatory amino acid ampa are rewarding when injected into the posterior hypothalamus and ventral tegmental area. |
2004-11-24 |
2023-08-12 |
rat |
| Satoshi Ikemoto, Brian M Witkin, Abraham Zangen, Roy A Wis. Rewarding effects of AMPA administration into the supramammillary or posterior hypothalamic nuclei but not the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 25. 2004-11-24. PMID:15215298. |
ampa injections into the supramammillary nucleus, but not the ventral tegmental area, induced conditioned place preference. |
2004-11-24 |
2023-08-12 |
rat |
| Satoshi Ikemoto, Brian M Witkin, Abraham Zangen, Roy A Wis. Rewarding effects of AMPA administration into the supramammillary or posterior hypothalamic nuclei but not the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 25. 2004-11-24. PMID:15215298. |
ampa injections into the supramammillary nucleus, but not the ventral tegmental area, also increased extracellular dopamine concentrations in the nucleus accumbens. |
2004-11-24 |
2023-08-12 |
rat |
| Stephanie C Licata, Heath D Schmidt, R Christopher Pierc. Suppressing calcium/calmodulin-dependent protein kinase II activity in the ventral tegmental area enhances the acute behavioural response to cocaine but attenuates the initiation of cocaine-induced behavioural sensitization in rats. The European journal of neuroscience. vol 19. issue 2. 2004-03-18. PMID:14725635. |
in the present experiments we administered an alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (ampa) receptor antagonist (cnqx), n-methyl-d-aspartate (nmda) receptor antagonist (ap-5), or l-type calcium channel blocker (diltiazem) directly into the ventral tegmental area (vta) before each of four daily systemic cocaine injections in order to assess their influence on the initiation phase of behavioural sensitization. |
2004-03-18 |
2023-08-12 |
mouse |
| Stephanie C Licata, Heath D Schmidt, R Christopher Pierc. Suppressing calcium/calmodulin-dependent protein kinase II activity in the ventral tegmental area enhances the acute behavioural response to cocaine but attenuates the initiation of cocaine-induced behavioural sensitization in rats. The European journal of neuroscience. vol 19. issue 2. 2004-03-18. PMID:14725635. |
the present findings also suggest that increased calcium influx through ampa receptors, nmda receptors and l-type calcium channels on dopaminergic neurons in the vta contributes significantly to the initiation of behavioural sensitization by amplifying calcium signalling through cam-kii. |
2004-03-18 |
2023-08-12 |
mouse |
| Johanna L Gutlerner, Esther Chapin Penick, Eric M Snyder, Julie A Kaue. Novel protein kinase A-dependent long-term depression of excitatory synapses. Neuron. vol 36. issue 5. 2003-01-16. PMID:12467595. |
here we show that in common with other forms of ltd, vta ltd results from a selective decrease in ampa receptor function accompanied by a decrease in cell surface ampa receptors. |
2003-01-16 |
2023-08-12 |
Not clear |
| William A Carlezon, Eric J Nestle. Elevated levels of GluR1 in the midbrain: a trigger for sensitization to drugs of abuse? Trends in neurosciences. vol 25. issue 12. 2003-01-13. PMID:12446127. |
here, we review evidence that the ability of drugs of abuse to elevate levels of the glur1 subunit of ampa glutamate receptors in the ventral tegmental area (vta) of the midbrain is crucial for the development of sensitization. |
2003-01-13 |
2023-08-12 |
Not clear |
| George Panagis, Andreas Kastellaki. The effects of ventral tegmental administration of GABA(A), GABA(B), NMDA and AMPA receptor agonists on ventral pallidum self-stimulation. Behavioural brain research. vol 131. issue 1-2. 2002-05-03. PMID:11844578. |
here, using the curve-shift intracranial self-stimulation method, we studied the effects of muscimol (gaba(a) agonist), baclofen (gaba(b) agonist), nmda and ampa, microinjected bilaterally into the vta on the rewarding efficacy of vp self-stimulation. |
2002-05-03 |
2023-08-12 |
Not clear |
| Wenxiao Lu, Lisa M Monteggia, Marina E Wol. Repeated administration of amphetamine or cocaine does not alter AMPA receptor subunit expression in the rat midbrain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 26. issue 1. 2002-03-05. PMID:11751027. |
we previously reported that ventral tegmental area (vta) dopamine neurons are supersensitive to ampa when recorded three days after discontinuing repeated amphetamine or cocaine administration. |
2002-03-05 |
2023-08-12 |
rat |
| Wenxiao Lu, Lisa M Monteggia, Marina E Wol. Repeated administration of amphetamine or cocaine does not alter AMPA receptor subunit expression in the rat midbrain. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 26. issue 1. 2002-03-05. PMID:11751027. |
our results suggest that enhanced responsiveness of vta dopamine neurons to ampa after withdrawal from repeated stimulant administration involves mechanisms more complex than increased expression of ampa receptor subunits. |
2002-03-05 |
2023-08-12 |
rat |
| W A Carlezon, M S Todtenkopf, D L McPhie, P Pimentel, A M Pliakas, J R Stellar, M Trzcinsk. Repeated exposure to rewarding brain stimulation downregulates GluR1 expression in the ventral tegmental area. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 25. issue 2. 2001-10-11. PMID:11425507. |
we report that repeated exposure to rewarding stimulation of the medial forebrain bundle (mfb) selectively decreases expression of glur1 (an ampa receptor subunit) in the vta, without effect on expression of several other proteins (glur2, nmdar1, tyrosine hydroxylase). |
2001-10-11 |
2023-08-12 |
Not clear |
| M Giorgetti, G Hotsenpiller, P Ward, T Teppen, M E Wol. Amphetamine-induced plasticity of AMPA receptors in the ventral tegmental area: effects on extracellular levels of dopamine and glutamate in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487659. |
amphetamine-induced plasticity of ampa receptors in the ventral tegmental area: effects on extracellular levels of dopamine and glutamate in freely moving rats. |
2001-08-30 |
2023-08-12 |
rat |
| M Giorgetti, G Hotsenpiller, P Ward, T Teppen, M E Wol. Amphetamine-induced plasticity of AMPA receptors in the ventral tegmental area: effects on extracellular levels of dopamine and glutamate in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487659. |
previous electrophysiological studies suggested that the initiation of behavioral sensitization to cocaine and amphetamine involves a transient increase in ampa receptor responsiveness in the ventral tegmental area (vta). |
2001-08-30 |
2023-08-12 |
rat |
| M Giorgetti, G Hotsenpiller, P Ward, T Teppen, M E Wol. Amphetamine-induced plasticity of AMPA receptors in the ventral tegmental area: effects on extracellular levels of dopamine and glutamate in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487659. |
to test this, we used in vivo microdialysis to examine the effects of intra-vta administration of ampa (10 microm) and nmda (100 microm) on dopamine (da) and glutamate efflux in the vta and the nucleus accumbens (nac), an important target of vta da neurons. |
2001-08-30 |
2023-08-12 |
rat |
| M Giorgetti, G Hotsenpiller, P Ward, T Teppen, M E Wol. Amphetamine-induced plasticity of AMPA receptors in the ventral tegmental area: effects on extracellular levels of dopamine and glutamate in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487659. |
we compared rats treated for 5 d with saline or 5 mg/kg amphetamine and withdrawn for 3 or 10-14 d. after 3 d of withdrawal, intra-vta ampa increased both nac and vta da levels to a greater extent in the amphetamine group, whereas nmda produced similar effects in the saline and amphetamine groups. |
2001-08-30 |
2023-08-12 |
rat |
| M Giorgetti, G Hotsenpiller, P Ward, T Teppen, M E Wol. Amphetamine-induced plasticity of AMPA receptors in the ventral tegmental area: effects on extracellular levels of dopamine and glutamate in freely moving rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 16. 2001-08-30. PMID:11487659. |
in addition, intra-vta ampa but not nmda increased both vta and nac glutamate levels in rats tested 3 d after the last injection of amphetamine but not in saline controls. |
2001-08-30 |
2023-08-12 |
rat |