| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Züleyha Doğanyiğit, Aslı Okan, Seher Yılmaz, A Cihangir Uğuz, Enes Akyü. Gender-related variation expressions of neuroplastin TRAF6, GluA1, GABA(A) receptor, and PMCA in cortex, hippocampus, and brainstem in an experimental epilepsy model. Synapse (New York, N.Y.). vol 78. issue 2. 2024-03-04. PMID:38436644. |
it was observed that neuroplastin and related proteins tnf receptor-associated factor 6 (traf6), gamma amino butyric acid type a receptors [(gaba(a)], and plasma membrane ca2+ atpase (pmca) protein immunoreactivity levels increased especially in the male hippocampus, and only ampa receptor subunit type 1 (glua1) immunoreactivity decreased, unlike other proteins. |
2024-03-04 |
2024-03-06 |
rat |
| David A Crowe, Andrew Willow, Rachael K Blackman, Adele L DeNicola, Matthew V Chafee, Bagrat Amirikia. A prefrontal network model operating near steady and oscillatory states links spike desynchronization and synaptic deficits in schizophrenia. eLife. vol 13. 2024-02-06. PMID:38319151. |
we analyze how the balance between ampa and nmda components of recurrent excitation and gaba inhibition in the network influence oscillatory spike synchrony to inform the biological data. |
2024-02-06 |
2024-02-09 |
monkey |
| Mansi Singh, Siva Prasad Pand. The Role of monosodium glutamate (MSG) in Epilepsy and other Neurodegenerative Diseases: Phytochemical-based Therapeutic Approaches and Mechanisms. Current pharmaceutical biotechnology. 2023-07-27. PMID:37496245. |
msg acts on glutamate receptors, specifically nmda and ampa receptors, leading to an imbalance between excitatory glutamate and inhibitory gaba neurotransmission. |
2023-07-27 |
2023-08-14 |
Not clear |
| Timo Kirschstein, Rüdiger Köhlin. Functional changes in neuronal circuits due to antibody-driven autoimmune response. Neurobiology of disease. 2023-07-06. PMID:37414365. |
several of such antibodies have by now been identified such as igg directed against nmda-receptors, ampa receptors, gaba |
2023-07-06 |
2023-08-14 |
Not clear |
| Ruksar Sande, Gaurav Doshi, Angel Goda. Deciphering the role of metal and non-metals in the treatment of epilepsy. Neurochemistry international. 2023-05-13. PMID:37178926. |
copper acts in the cns in an identical manner, i.e., by blocking both ampa mediated and gaba mediated neuronal transmission. |
2023-05-13 |
2023-08-14 |
Not clear |
| Ireneusz Chmie. Ketogenic diet in therapy of bipolar affective disorder - case report and literature review. Psychiatria polska. vol 56. issue 6. 2023-04-25. PMID:37098202. |
the effects of the diet may be related to, among others, the influence on ionic channels and increase in blood acidity (similarly to mood stabilisers), increase in gamma-aminobutyric acid (gaba) concentration, modulation of gabaa receptors and blocking of ampa receptors by medium-chain fatty acids. |
2023-04-25 |
2023-08-14 |
Not clear |
| Somayeh Hajipour, Maryam Khombi Shooshtari, Yaghoob Farbood, Seyed Ali Mard, Alireza Sarkaki, Homeira Moradi Chameh, Neda Sistani Karampour, Samireh Ghafour. Fingolimod administration following hypoxia induced neonatal seizure can restore impaired long-term potentiation and memory performance in adult rats. Neuroscience. 2023-03-29. PMID:36990271. |
finally, the gene expression of nr2a subunit of n-methyl-d-aspartic acid (nmda) receptor, glur2 subunit of (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) ampa receptor and γ2 subunit of γ-aminobutyric acid (gaba |
2023-03-29 |
2023-08-14 |
rat |
| Todd M Mowery, Preston E Garraght. Adult neuroplasticity employs developmental mechanisms. Frontiers in systems neuroscience. vol 16. 2023-02-10. PMID:36762289. |
ultimately, mowery and colleagues conducted a series of experiments that carefully tracked the levels of expression of several subunits of glutamate (ampa and nmda) and gaba (gabaa and gabab) receptor complexes in primate somatosensory cortex at several time points after peripheral nerve injury. |
2023-02-10 |
2023-08-14 |
rat |
| Ankita Rajput, Palvi Sharma, Nitish Kumar, Sarabjit Kaur, Saroj Aror. Neuroprotective activity of novel phenanthrene derivative from Grewia tiliaefolia by in vitro and in silico studies. Scientific reports. vol 13. issue 1. 2023-02-10. PMID:36765125. |
in silico study was conducted to predict its action on proteins playing crucial role in neurological and neurodegenerative disorders such as gamma amino butyric acid (gaba) receptor and glutamate α amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid (glu ampa) receptor in epilepsy and ache enzyme in alzheimer's diseases. |
2023-02-10 |
2023-08-14 |
Not clear |
| Binghan Xue, Xiangying Meng, Joseph P Y Kao, Patrick O Kanol. Age-related changes in excitatory and inhibitory intra-cortical circuits in auditory cortex of C57Bl/6 mice. Hearing research. vol 429. 2023-01-26. PMID:36701895. |
aging is accompanied by alteration in normal inhibitory (gaba) neurotransmission, and changes in excitatory (nmda and ampa) synapses in the auditory cortex (actx). |
2023-01-26 |
2023-08-14 |
mouse |
| H Kida, R Kawakami, K Sakai, H Otaku, K Imamura, Thiri-Zin Han, Y Sakimoto, D Mitsushim. Motor training promotes both synaptic and intrinsic plasticity of layer V pyramidal neurons in the primary motor cortex. The Journal of physiology. 2022-12-14. PMID:36515167. |
the training reduced presynaptic gaba release in early phase, but strengthened ampa receptor-mediated excitatory synapses in later phase: acquired motor performance after training correlated with the strength of excitatory synapses rather than inhibitory synapses. |
2022-12-14 |
2023-08-14 |
Not clear |
| Stefano Masoli, Martina Francesca Rizza, Marialuisa Tognolina, Francesca Prestori, Egidio D'Angel. Computational models of neurotransmission at cerebellar synapses unveil the impact on network computation. Frontiers in computational neuroscience. vol 16. 2022-11-17. PMID:36387305. |
these mechanisms have been accurately modeled for different synapses and receptor types (ampa, nmda, and gaba) of the cerebellar cortical network, allowing simulation of their impact on computation. |
2022-11-17 |
2023-08-14 |
Not clear |
| Sijun Li, Hongmi Huang, Xin Wei, Lin Ye, Meigang Ma, Min Ling, Yuan W. The recycling of AMPA receptors/GABAa receptors is related to neuronal excitation/inhibition imbalance and may be regulated by KIF5A. Annals of translational medicine. vol 10. issue 20. 2022-11-17. PMID:36388788. |
excitation/inhibition imbalance (e/i imbalance), which involves an increase of alpha-amino-3-hydroxy-5-methyl-4-isoxazole (ampa) receptors (ampars) and decrease of gamma-aminobutyric acid type a (gaba) type a receptors (gabaars) on the neuron surface, has been documented in the pathogenesis of seizures. |
2022-11-17 |
2023-08-14 |
Not clear |
| Masoud Amiri, Amir Homayoun Jafari, Bahador Makkiabadi, Soheila Nazar. Recognizing intertwined patterns using a network of spiking pattern recognition platforms. Scientific reports. vol 12. issue 1. 2022-11-14. PMID:36376426. |
all networks are developed based on a similar structure in the input image coding, model of neurons (pyramidal neurons and interneurons) and synapses (excitatory ampa and inhibitory gaba currents), and learning procedure. |
2022-11-14 |
2023-08-14 |
Not clear |
| Laura Bayón-Cordero, Blanca Isabel Ochoa-Bueno, Asier Ruiz, Marina Ozalla, Carlos Matute, María Victoria Sánchez-Góme. GABA Receptor Agonists Protect From Excitotoxic Damage Induced by AMPA in Oligodendrocytes. Frontiers in pharmacology. vol 13. 2022-08-12. PMID:35959434. |
gaba receptor agonists protect from excitotoxic damage induced by ampa in oligodendrocytes. |
2022-08-12 |
2023-08-14 |
Not clear |
| Brice Miller, Ashli Powell, Berenice A Gutierrez, Agenor Limo. Microtransplantation of Synaptic Membranes to Reactivate Human Synaptic Receptors for Functional Studies. Journal of visualized experiments : JoVE. issue 185. 2022-08-08. PMID:35938847. |
the protocol also provides the methodological strategy to obtain consistent and reliable responses of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) and γ-aminobutyric acid (gaba) receptors, as well as novel detailed methods that are used for normalization and rigorous data analysis. |
2022-08-08 |
2023-08-14 |
human |
| Ludovic D Langlois, Prabhuanand Selvaraj, Sarah C Simmons, Shawn Gouty, Yumin Zhang, Fereshteh S Nugen. Repetitive mild traumatic brain injury induces persistent alterations in spontaneous synaptic activity of hippocampal CA1 pyramidal neurons. IBRO neuroscience reports. vol 12. 2022-06-24. PMID:35746968. |
using a repetitive closed head injury (3xchi) mouse model of mtbi, we examined the alteration of spontaneous synaptic transmission onto hippocampal ca1 pyramidal neurons by recording spontaneous excitatory ampa receptor (ampar)- and inhibitory gaba |
2022-06-24 |
2023-08-14 |
mouse |
| Arianna De Rosa, Andrea Fontana, Tommaso Nuzzo, Martina Garofalo, Anna Di Maio, Daniela Punzo, Massimiliano Copetti, Alessandro Bertolino, Francesco Errico, Antonio Rampino, Andrea de Bartolomeis, Alessandro Usiell. Machine Learning algorithm unveils glutamatergic alterations in the post-mortem schizophrenia brain. NPJ schizophrenia. vol 8. issue 1. 2022-02-26. PMID:35217646. |
moreover, by quantitative rt-pcr and western blotting we analyzed, respectively, the mrna and protein levels of pre- and post-synaptic key molecules involved in the glutamatergic synapse functioning, including glutamate receptors (nmda, ampa, metabotropic), their interacting scaffolding proteins (psd-95, homer1b/c), plasma membrane and vesicular glutamate transporters (eaat1, eaat2, vglut1, vglut2), enzymes involved either in glutamate-dependent gaba neurotransmitter synthesis (gad65 and 67), or in post-synaptic nmda receptor-mediated signaling (camkiiα) and the pre-synaptic marker synapsin-1. |
2022-02-26 |
2023-08-13 |
Not clear |
| Nick Weir, Bob Stevens, Sarah Wagner, Amanda Miles, Graham Ball, Charlotte Howard, Joseph Chemmarappally, Martin McGinnity, Alan Jeffrey Hargreaves, Chris Tinsle. Aligned Poly-l-lactic Acid Nanofibers Induce Self-Assembly of Primary Cortical Neurons into 3D Cell Clusters. ACS biomaterials science & engineering. 2022-01-27. PMID:35084839. |
these clusters were viable for 28 days and responsive to ampa and gaba. |
2022-01-27 |
2023-08-13 |
rat |
| Alberto Marcos, Inmaculada Ballesteros-Yáñez, Carlos A Castillo-Sarmiento, Felipe Pardo, David Roura-Martínez, José Ramón Muñoz-Rodríguez, Alejandro Higuera-Matas, Emilio Ambrosi. The interactions of alcohol and cocaine regulate the expression of genes involved in the GABAergic, glutamatergic and endocannabinoid systems of male and female rats. Neuropharmacology. 2021-12-29. PMID:34965406. |
brain samples from the medial prefrontal cortex, nucleus accumbens, hippocampus and amygdala were extracted to analyse the mrna expression of genes encoding subunits of the gaba, nmda and ampa receptors, as well as the expression of the cb1 receptor, and that of enzymes related to the biosynthesis and degradation of endocannabinoids. |
2021-12-29 |
2023-08-13 |
rat |