| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y M Geng, J T Xue, J P Su, H Y L. Molecular mechanism of action of valproate acid alone or in combination with chlorpromazine in the epigenetic regulation of schizophrenia. Journal of biological regulators and homeostatic agents. vol 32. issue 6. 2019-06-14. PMID:30574748. |
the real time pcr assay was used to detect the mrna expression changes of gaba system gene [gabbr1 (gaba b receptor 1)], gad1 (glutamic acid decarboxylase1), gad2 (glutamic acid decarboxylase2), lipase metabolic key enzyme lpl (lipoprotein lipase) gene, glutamate neurotransmitter gene gria2 (ampa subtype glutamate receptors 2), inward rectifier potassium channel members kcnj4 (potassium voltage-gated channel subfamily j member 4) and neuropeptide signal gene tac1 (tachykinin precursor 1,tac1) in four brain regions: the prefrontal cortex (pc), the amygdala (am), the caudate-putamen (cpu) and the hippocampus (hip). |
2019-06-14 |
2023-08-13 |
rat |
| Jian-Ping Zhao, Akira Yoshi. Hyperexcitability of the local cortical circuit in mouse models of tuberous sclerosis complex. Molecular brain. vol 12. issue 1. 2019-06-10. PMID:30683131. |
to decipher the synaptic substrate of hyperexcitability, we examined pan-neuronal tsc1 knockout mouse and found a reduction in surface expression of a gaba receptor (gabar) subunit but not ampa receptor (ampar) subunit. |
2019-06-10 |
2023-08-13 |
mouse |
| Carol A Dannenhoffer, Elena I Varlinskaya, Linda Patia Spea. Effects of AMPA receptor antagonist, NBQX, and extrasynaptic GABA Physiology & behavior. vol 194. 2019-04-29. PMID:29800636. |
effects of ampa receptor antagonist, nbqx, and extrasynaptic gaba adolescence is characterized by high significance of social interactions, along with a propensity to exhibit social facilitating effects of ethanol while being less sensitive than adults to the inhibition of social behavior that emerges at higher doses of ethanol. |
2019-04-29 |
2023-08-13 |
rat |
| Carol A Dannenhoffer, Elena I Varlinskaya, Linda Patia Spea. Effects of AMPA receptor antagonist, NBQX, and extrasynaptic GABA Physiology & behavior. vol 194. 2019-04-29. PMID:29800636. |
the roles of ampa and extrasynaptic gaba |
2019-04-29 |
2023-08-13 |
rat |
| Hanna Dumanska, Nickolai Veselovsk. Short-term hypoxia induces bidirectional pathological long-term plasticity of neurotransmission in visual retinocollicular pathway. Experimental eye research. vol 179. 2019-04-15. PMID:30393125. |
pharmacologically isolated n-methyl-d-aspartate receptor (nmda)-, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (ampa)- and gamma-aminobutyric acid receptor (gaba |
2019-04-15 |
2023-08-13 |
Not clear |
| Cerine C Hansen, Hanna Ljung, Eylert Brodtkorb, Arne Reimer. Mechanisms Underlying Aggressive Behavior Induced by Antiepileptic Drugs: Focus on Topiramate, Levetiracetam, and Perampanel. Behavioural neurology. vol 2018. 2019-04-15. PMID:30581496. |
serotonin (5-ht) and gaba, and particularly glutamate (via the ampa receptor), seem to play key roles. |
2019-04-15 |
2023-08-13 |
Not clear |
| Jon-Ruben van Rhijn, Simon E Fisher, Sonja C Vernes, Nael Nadif Kasr. Foxp2 loss of function increases striatal direct pathway inhibition via increased GABA release. Brain structure & function. vol 223. issue 9. 2019-03-08. PMID:30187194. |
our data show that heterozygous loss of foxp2 decreases excitatory (ampa receptor-mediated) and increases inhibitory (gaba receptor-mediated) currents in d1 dopamine receptor positive msns of juvenile and adult mice. |
2019-03-08 |
2023-08-13 |
mouse |
| Leila Dehestani, Nematollah Ahangar, Seyedeh Mahdieh Hashemi, Hamid Irannejad, Patrick Honarchian Masihi, Aidin Shakiba, Saeed Emam. Design, synthesis, in vivo and in silico evaluation of phenacyl triazole hydrazones as new anticonvulsant agents. Bioorganic chemistry. vol 78. 2019-01-28. PMID:29550532. |
molecular docking studies of compound 3h with different targets (nmda, ampa, gaba |
2019-01-28 |
2023-08-13 |
Not clear |
| Verginia C Cuzon Carlson, Kathleen A Grant, David M Lovinge. Synaptic adaptations to chronic ethanol intake in male rhesus monkey dorsal striatum depend on age of drinking onset. Neuropharmacology. vol 131. 2018-11-13. PMID:29241653. |
striatal neuroadaptations were examined using whole-cell patch clamp electrophysiology to record ampa receptor-mediated miniature excitatory postsynaptic currents (mepscs) and gaba |
2018-11-13 |
2023-08-13 |
monkey |
| Hiroyuki Kida, Dai Mitsushim. Mechanisms of motor learning mediated by synaptic plasticity in rat primary motor cortex. Neuroscience research. vol 128. 2018-08-21. PMID:28951322. |
using this model, we investigated the effects of motor training on both ampa receptor-mediated excitatory synapses and gaba |
2018-08-21 |
2023-08-13 |
rat |
| Christina Herold, Christina Paulitschek, Nicola Palomero-Gallagher, Onur Güntürkün, Karl Zille. Transmitter receptors reveal segregation of the arcopallium/amygdala complex in pigeons (Columba livia). The Journal of comparative neurology. vol 526. issue 3. 2018-07-23. PMID:29063593. |
therefore, we analyzed binding site densities for glutamatergic ampa, nmda and kainate, gabaergic gaba |
2018-07-23 |
2023-08-13 |
pigeon |
| Soheila Nazari, Karim Faez, Mahyar Janahmad. A new approach to detect the coding rule of the cortical spiking model in the information transmission. Neural networks : the official journal of the International Neural Network Society. vol 99. 2018-07-18. PMID:29355733. |
in order to move towards this important goal, computational neuroscience tools can be useful so, we simulated a large-scale network of excitatory and inhibitory spiking neurons with synaptic connections consisting of ampa and gaba currents as a model of cortical populations. |
2018-07-18 |
2023-08-13 |
Not clear |
| Soheila Nazari, Karim Faez, Mahyar Janahmad. A new approach to detect the coding rule of the cortical spiking model in the information transmission. Neural networks : the official journal of the International Neural Network Society. vol 99. 2018-07-18. PMID:29355733. |
spiking network was equipped with spike-based unsupervised weight optimization based on the dynamical behavior of the excitatory (ampa) and inhibitory (gaba) synapses using spike timing dependent plasticity (stdp) on the mnist benchmark and we specified how the generated lfp by the network contained information about input patterns. |
2018-07-18 |
2023-08-13 |
Not clear |
| Jiao Tian, Zhen Tian, Shu-Li Qin, Pu-Yu Zhao, Xun Jiang, Zhen Tia. Anxiolytic-like effects of α-asarone in a mouse model of chronic pain. Metabolic brain disease. vol 32. issue 6. 2018-07-03. PMID:28913780. |
asr administration reversed the up-regulation of glur1-containing α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (ampa) receptors, nr2a-containing n-methyl-d-aspartate (nmda) receptors and down-regulation of γ-aminobutyric acid a (gaba |
2018-07-03 |
2023-08-13 |
mouse |
| Li-Rong Shao, Carl E Stafstro. Glycolytic inhibition by 2-deoxy-d-glucose abolishes both neuronal and network bursts in an in vitro seizure model. Journal of neurophysiology. vol 118. issue 1. 2018-03-26. PMID:28404824. |
the effect of glycolytic inhibition on neuronal firing was tested in spontaneously active hippocampal neurons (ca3) when synaptic transmission was left intact or blocked with ampa, nmda, and gaba |
2018-03-26 |
2023-08-13 |
Not clear |
| Liangchen Zhao, Tianji Liu, Rutao Xu, Liu He, Man Duan, Dejun X. Mechanism of neuronal activity and synaptic transmission in rostral ventrolateral medulla. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 42. 2018-02-26. PMID:28442196. |
with continues perfusion of artificial cerebrospinal fluid (acsf), the spontaneous firing of slices and amplitudes were assayed by conventional whole cell patch-clamp recording after addition of gamma-aminobutyric acid (gaba), α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (ampa) and n-methyl d-aspartate (nmda). |
2018-02-26 |
2023-08-13 |
rat |
| Liangchen Zhao, Tianji Liu, Rutao Xu, Liu He, Man Duan, Dejun X. Mechanism of neuronal activity and synaptic transmission in rostral ventrolateral medulla. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 42. 2018-02-26. PMID:28442196. |
the spontaneous firing of neurons in rvlm were inhibited by gaba (p<0.001) while were promoted by nmda or ampa (p<0.01 or p<0.001). |
2018-02-26 |
2023-08-13 |
rat |
| Madhusudhanan M Keralapurath, Sherri B Briggs, John J Wagne. Cocaine self-administration induces changes in synaptic transmission and plasticity in ventral hippocampus. Addiction biology. vol 22. issue 2. 2018-01-30. PMID:26692207. |
these findings suggest the presence of synergistic effects of enhanced ampa and diminished gamma-aminobutyric acid neurotransmission under physiological conditions in the ca1 region of cocaine-taking animals, supporting the conclusion that persisting enhancement of ampa-mediated transmission and/or inhibition of gamma-aminobutyric acid-mediated transmission promoted a chronic state of potentiation that partially occluded further ltp. |
2018-01-30 |
2023-08-13 |
rat |
| Saeed Sadigh-Eteghad, Alireza Majdi, Javad Mahmoudi, Samad E J Golzari, Mahnaz Taleb. Astrocytic and microglial nicotinic acetylcholine receptors: an overlooked issue in Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996). vol 123. issue 12. 2018-01-29. PMID:27262818. |
these receptors are also involved in neurotransmission and gliotransmission through indirect interaction with n-methyl-d-aspartate (nmda) and a-amino-3-hydroxy-5-methyl-4 isoxazolepropionic acid (ampa) receptors as well as gamma-aminobutyric acid (gaba) and intracellular calcium regulation. |
2018-01-29 |
2023-08-13 |
Not clear |
| Tao Wang, Rui-Li Guan, Ming-Chao Liu, Xue-Feng Shen, Jing Yuan Chen, Ming-Gao Zhao, Wen-Jing Lu. Lead Exposure Impairs Hippocampus Related Learning and Memory by Altering Synaptic Plasticity and Morphology During Juvenile Period. Molecular neurobiology. vol 53. issue 6. 2017-12-29. PMID:26141123. |
we found that nmda and ampa receptor-mediated current was inhibited, whereas the gaba synaptic transmission was normal in pb-exposed rats. |
2017-12-29 |
2023-08-13 |
rat |