All Relations between \u03b1-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and glycine

Publication Sentence Publish Date Extraction Date Species
Jurgen Buekers, Sylvie Remy, Jos Bessems, Eva Govarts, Loïc Rambaud, Margaux Riou, Thorhallur I Halldorsson, Kristin Ólafsdóttir, Nicole Probst-Hensch, Priska Ammann, Till Weber, Marike Kolossa-Gehring, Marta Esteban-López, Argelia Castaño, Helle Raun Andersen, Greet Schoeter. Glyphosate and AMPA in Human Urine of HBM4EU-Aligned Studies: Part B Adults. Toxics. vol 10. issue 10. 2022-10-26. PMID:36287833. within hbm4eu, human biomonitoring (hbm) studies measuring glyphosate (gly) and aminomethylphosphonic acid (ampa) in urine samples from the general adult population were aligned and quality-controlled/assured. 2022-10-26 2023-08-14 human
Jurgen Buekers, Sylvie Remy, Jos Bessems, Eva Govarts, Loïc Rambaud, Margaux Riou, Thorhallur I Halldorsson, Kristin Ólafsdóttir, Nicole Probst-Hensch, Priska Ammann, Till Weber, Marike Kolossa-Gehring, Marta Esteban-López, Argelia Castaño, Helle Raun Andersen, Greet Schoeter. Glyphosate and AMPA in Human Urine of HBM4EU-Aligned Studies: Part B Adults. Toxics. vol 10. issue 10. 2022-10-26. PMID:36287833. the 95th percentiles (p95) ranged between 0.24 and 0.37 µg/l urine for gly and between 0.21 and 0.38 µg/l for ampa. 2022-10-26 2023-08-14 human
Jurgen Buekers, Sylvie Remy, Jos Bessems, Eva Govarts, Loïc Rambaud, Margaux Riou, Thorhallur I Halldorsson, Kristin Ólafsdóttir, Nicole Probst-Hensch, Priska Ammann, Till Weber, Marike Kolossa-Gehring, Marta Esteban-López, Argelia Castaño, Helle Raun Andersen, Greet Schoeter. Glyphosate and AMPA in Human Urine of HBM4EU-Aligned Studies: Part B Adults. Toxics. vol 10. issue 10. 2022-10-26. PMID:36287833. however, the controversy on carcinogenicity, potential endocrine effects and the absence of a group adi for gly and ampa induce uncertainty to the risk assessment. 2022-10-26 2023-08-14 human
Rajapaksha Haddokara Gedara Rasika Wathsala, Elena Catasús Folgueras, Letizia Iuffrida, Marco Candela, Roberto Gotti, Jessica Fiori, Silvia Franzellitt. Glyphosate and its breakdown product AMPA elicit cytoprotective responses in haemocytes of the Mediterranean mussel (Mytilus galloprovincialis). Environmental toxicology and pharmacology. 2022-10-10. PMID:36216252. this study investigates the effects of glyphosate (gly) and its metabolite ampa on cytoprotective and detoxification mechanisms in haemocytes of mytilus galloprovincialis. 2022-10-10 2023-08-14 Not clear
Rajapaksha Haddokara Gedara Rasika Wathsala, Elena Catasús Folgueras, Letizia Iuffrida, Marco Candela, Roberto Gotti, Jessica Fiori, Silvia Franzellitt. Glyphosate and its breakdown product AMPA elicit cytoprotective responses in haemocytes of the Mediterranean mussel (Mytilus galloprovincialis). Environmental toxicology and pharmacology. 2022-10-10. PMID:36216252. cells were treated in vitro with 0.1 and 1.0µg/l gly, 0.1µg/l, 0.1 and 1.0µg/l ampa, or two mixtures gly+ampa (0.1µg/l gly + 0.1µg/l ampa, 1.0µg/l gly + 1.0µg/l ampa). 2022-10-10 2023-08-14 Not clear
Rajapaksha Haddokara Gedara Rasika Wathsala, Elena Catasús Folgueras, Letizia Iuffrida, Marco Candela, Roberto Gotti, Jessica Fiori, Silvia Franzellitt. Glyphosate and its breakdown product AMPA elicit cytoprotective responses in haemocytes of the Mediterranean mussel (Mytilus galloprovincialis). Environmental toxicology and pharmacology. 2022-10-10. PMID:36216252. gly and ampa increased mxr efflux activity and modulated expression of the abcb transcript encoding a mxr related abc transporter p-glycoprotein. 2022-10-10 2023-08-14 Not clear
Jurgen Buekers, Sylvie Remy, Jos Bessems, Eva Govarts, Loïc Rambaud, Margaux Riou, Janja Snoj Tratnik, Anja Stajnko, Andromachi Katsonouri, Konstantinos C Makris, Annelies De Decker, Bert Morrens, Nina Vogel, Marike Kolossa-Gehring, Marta Esteban-López, Argelia Castaño, Helle Raun Andersen, Greet Schoeter. Glyphosate and AMPA in Human Urine of HBM4EU Aligned Studies: Part A Children. Toxics. vol 10. issue 8. 2022-08-25. PMID:36006149. the ratio of ampa (aminomethylphosphonic acid; main metabolite of gly) to gly at molar basis was on average 2.2 and the ratio decreased with higher gly concentrations, suggesting that other sources of ampa, independent of metabolism of gly to ampa in the monitored participants, may concurrently operate. 2022-08-25 2023-08-14 human
Anthony Estienne, Mathias Fréville, Guillaume Bourdon, Christelle Ramé, Joël Delaveau, Christophe Rat, Marine Chahnamian, Aurélien Brionne, Pascal Chartrin, Hans Adriensen, François Lecompte, Pascal Froment, Joëlle Dupon. Chronic dietary exposure to a glyphosate-based herbicide results in reversible increase early embryo mortality in chicken. Ecotoxicology and environmental safety. vol 241. 2022-06-09. PMID:35679729. despite the accumulation of gly and its metabolite aminomethylphosphonic acid (ampa) in the hen blood plasma, the body weight and laying rate were similar in gbh and ct animals. 2022-06-09 2023-08-14 chicken
Anthony Estienne, Mathias Fréville, Guillaume Bourdon, Christelle Ramé, Joël Delaveau, Christophe Rat, Marine Chahnamian, Aurélien Brionne, Pascal Chartrin, Hans Adriensen, François Lecompte, Pascal Froment, Joëlle Dupon. Chronic dietary exposure to a glyphosate-based herbicide results in reversible increase early embryo mortality in chicken. Ecotoxicology and environmental safety. vol 241. 2022-06-09. PMID:35679729. we observed from the 4th day of exposure an accumulation of gly (but not ampa) only in the yolk of the eggs produced by the exposed hens. 2022-06-09 2023-08-14 chicken
Beatriz Alonso, Luciana Griffero, Heinkel Bentos Pereira, Lucía Pareja, Andrés Pérez Parad. Determination of glyphosate and AMPA in freshwater and soil from agroecosystems by 9-fluorenylmethoxycarbonyl chloride derivatization and liquid chromatography - fluorescence detection and tandem mass spectrometry. MethodsX. vol 9. 2022-06-06. PMID:35664042. the herbicide glyphosate (gly) and its metabolite aminophosphonic acid (ampa) are troublesome compounds for analysis in the environment. 2022-06-06 2023-08-14 Not clear
Beatriz Alonso, Luciana Griffero, Heinkel Bentos Pereira, Lucía Pareja, Andrés Pérez Parad. Determination of glyphosate and AMPA in freshwater and soil from agroecosystems by 9-fluorenylmethoxycarbonyl chloride derivatization and liquid chromatography - fluorescence detection and tandem mass spectrometry. MethodsX. vol 9. 2022-06-06. PMID:35664042. here we report a reliable technique for gly and ampa determination in freshwater and soils by means of derivatization with 9-fluorenylmethoxycarbonyl chloride (fmoc-cl) and further liquid chromatography with fluorescence detection (fld) and tandem mass spectrometry (ms/ms) analysis. 2022-06-06 2023-08-14 Not clear
Emma Ivantsova, Andrew S Wengrovitz, Christopher L Souders, Christopher J Martyniu. Developmental and behavioral toxicity assessment of glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) in zebrafish embryos/larvae. Environmental toxicology and pharmacology. 2022-05-03. PMID:35504511. the relative toxicity of glyphosate (gly) and its metabolite aminomethylphosphonic acid (ampa) to zebrafish were compared. 2022-05-03 2023-08-13 zebrafish
Emma Ivantsova, Andrew S Wengrovitz, Christopher L Souders, Christopher J Martyniu. Developmental and behavioral toxicity assessment of glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) in zebrafish embryos/larvae. Environmental toxicology and pharmacology. 2022-05-03. PMID:35504511. embryos/larvae were exposed to one dose of either gly (0.1, 1, or 10μm), ampa (0.1, 1, or 10μm), or a 1μm mixture for 7-days post-fertilization. 2022-05-03 2023-08-13 zebrafish
Emma Ivantsova, Andrew S Wengrovitz, Christopher L Souders, Christopher J Martyniu. Developmental and behavioral toxicity assessment of glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) in zebrafish embryos/larvae. Environmental toxicology and pharmacology. 2022-05-03. PMID:35504511. gly increased superoxide dismutase 2 mrna in larvae while ampa increased catalase and superoxide dismutase 1 in a concentration-specific manner. 2022-05-03 2023-08-13 zebrafish
Emma Ivantsova, Andrew S Wengrovitz, Christopher L Souders, Christopher J Martyniu. Developmental and behavioral toxicity assessment of glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) in zebrafish embryos/larvae. Environmental toxicology and pharmacology. 2022-05-03. PMID:35504511. gly increased cytochrome c oxidase subunit 4 isoform 1 and citrate synthase mrna in larvae while ampa decreased cytochrome c oxidase i and increased 3-hydroxyacyl coa dehydrogenase transcripts. 2022-05-03 2023-08-13 zebrafish
Emma Ivantsova, Andrew S Wengrovitz, Christopher L Souders, Christopher J Martyniu. Developmental and behavioral toxicity assessment of glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) in zebrafish embryos/larvae. Environmental toxicology and pharmacology. 2022-05-03. PMID:35504511. hyperactivity was noted in fish treated with gly, but not ampa nor the mixture. 2022-05-03 2023-08-13 zebrafish
Emma Ivantsova, Andrew S Wengrovitz, Christopher L Souders, Christopher J Martyniu. Developmental and behavioral toxicity assessment of glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) in zebrafish embryos/larvae. Environmental toxicology and pharmacology. 2022-05-03. PMID:35504511. anxiety-like behaviors were absent with exposure to gly or ampa. 2022-05-03 2023-08-13 zebrafish
Emma Ivantsova, Andrew S Wengrovitz, Christopher L Souders, Christopher J Martyniu. Developmental and behavioral toxicity assessment of glyphosate and its main metabolite aminomethylphosphonic acid (AMPA) in zebrafish embryos/larvae. Environmental toxicology and pharmacology. 2022-05-03. PMID:35504511. gly and ampa may exert differing effects at the molecular and behavioral level. 2022-05-03 2023-08-13 zebrafish
Konstantinos C Makris, Nikolaos Efthymiou, Corina Konstantinou, Elena Anastasi, Greet Schoeters, Marike Kolossa-Gehring, Andromachi Katsonour. Oxidative stress of glyphosate, AMPA and metabolites of pyrethroids and chlorpyrifos pesticides among primary school children in Cyprus. Environmental research. 2022-04-19. PMID:35439459. scientific evidence on the human toxicity of glyphosate (gly) and its primary metabolite, aminomethylphosphonic acid (ampa) is limited, particularly for children. 2022-04-19 2023-08-13 human
Karen Larsen, Adrián Lifschitz, Rocío Fernández San Juan, Guillermo Virke. Metabolic stability of glyphosate and its environmental metabolite (aminomethylphosphonic acid) in the ruminal content of cattle. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment. 2022-03-18. PMID:35302929. both gly and aminomethylphosphonic acid (ampa), its main degradation product, may be present in feedstuffs offered to dairy cows. 2022-03-18 2023-08-13 cattle