| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ewa Kopieczna-Grzebieniak, Ma\\xc5\\x82gorzata Gos. [The importance of regulation of endogenous methylarginine concentrations in clinical practice]. Przeglad lekarski vol 62 issue 12 2006 16786781 |
asymmetric dimethylarginine (adma) and n-mono-methylarginine (mma), are competitive inhibitors of nitric oxide synthases. |
2006-11-06 |
2023-01-24 |
Not clear |
| Ewa Kopieczna-Grzebieniak, Ma\\xc5\\x82gorzata Gos. [The importance of regulation of endogenous methylarginine concentrations in clinical practice]. Przeglad lekarski vol 62 issue 12 2006 16786781 |
the main aim of the present study is to pay attention to possibility of the modulation of asymmetric methyl-arginines concentration, what may be a new way of synthase nitric oxide activity regulation in vivo and may be useful in future therapy of patologies in which synthesis of no is troubled. |
2006-11-06 |
2023-01-24 |
Not clear |
| Ali O Yildirim, Patrick Bulau, Dariusz Zakrzewicz, Kamila E Kitowska, Norbert Weissmann, Friedrich Grimminger, Rory E Morty, Oliver Eickelber. Increased protein arginine methylation in chronic hypoxia: role of protein arginine methyltransferases. American journal of respiratory cell and molecular biology vol 35 issue 4 2006 16690984 |
asymmetric dimethylarginine (adma) is an endogenous inhibitor of nitric oxide synthesis. |
2006-11-01 |
2023-01-24 |
mouse |
| A Dooley, B Gao, N Bradley, D J Abraham, C M Black, M Jacobs, K R Bruckdorfe. Abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine. Rheumatology (Oxford, England) vol 45 issue 6 2006 16399843 |
abnormal nitric oxide metabolism in systemic sclerosis: increased levels of nitrated proteins and asymmetric dimethylarginine. |
2006-08-04 |
2023-01-24 |
human |
| James M Leipe. The DDAH-ADMA-NOS pathway. Therapeutic drug monitoring vol 27 issue 6 2006 16404814 |
an increasing number of reports in the literature indicate that endogenously produced inhibitors of nitric oxide synthase (nos),particularly asymmetric dimethylarginine (adma), regulate nitric oxide generation in disease states. |
2006-05-24 |
2023-01-24 |
Not clear |
| Caroline L Smith, Shelagh Anthony, Mike Hubank, James M Leiper, Patrick Vallanc. Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA. PLoS medicine vol 2 issue 10 2006 16190779 |
asymmetric dimethylarginine (adma) is a naturally occurring inhibitor of nitric oxide synthesis that accumulates in a wide range of diseases associated with endothelial dysfunction and enhanced atherosclerosis. |
2006-05-18 |
2023-01-24 |
Not clear |
| Jens Martens-Lobenhoffer, Stefanie M Bode-B\\xc3\\xb6ge. Fast and efficient determination of arginine, symmetric dimethylarginine, and asymmetric dimethylarginine in biological fluids by hydrophilic-interaction liquid chromatography-electrospray tandem mass spectrometry. Clinical chemistry vol 52 issue 3 2006 16384887 |
nitric oxide is synthesized from the amino acid arg by the enzyme endothelial nitric oxide synthase, which is competitively inhibited by the arginine metabolite asymmetric dimethylarginine (adma). |
2006-04-13 |
2023-01-24 |
Not clear |
| Caroline L Smith, Patrick Vallanc. Cardiovascular tests: use & limits of biochemical markers - therapeutic measurements of ADMA involved in cardiovascular disorders. Current pharmaceutical design vol 11 issue 17 2006 16026287 |
asymmetric dimethylarginine (adma) is an endogenously occurring methylarginine that inhibits nitric oxide synthesis. |
2006-04-10 |
2023-01-24 |
Not clear |
| Ruth L Stornetta, Diane L Rosin, Johnny R Simmons, Travis J McQuiston, Nina Vujovic, Matthew C Weston, Patrice G Guyene. Coexpression of vesicular glutamate transporter-3 and gamma-aminobutyric acidergic markers in rat rostral medullary raphe and intermediolateral cell column. The Journal of comparative neurology vol 492 issue 4 2006 16228993 |
vglut3-ir terminals formed approximately equal numbers of symmetric and asymmetric synapses onto presumed preganglionic neurons (nitric oxide synthase-ir profiles) or gaba-ir dendrites in iml, and terminals immunoreactive for both vglut3 and gaba always formed symmetric synapses. |
2006-01-19 |
2023-01-24 |
rat |
| Alessandra Testa, Belinda Spoto, Giovanni Tripepi, Francesca Mallamaci, Lorenzo Malatino, Pasquale Fatuzzo, Renke Maas, Rainer Boeger, Carmine Zoccal. The GLU298ASP variant of nitric oxide synthase interacts with asymmetric dimethyl arginine in determining cardiovascular mortality in patients with end-stage renal disease. Journal of hypertension vol 23 issue 10 2005 16148605 |
impaired nitric oxide generation and accumulation of the endogenous inhibitor of nitric oxide synthase (nos), asymmetric dimethylarginine (adma), have been identified as strong predictors of cardiovascular outcomes in patients with end-stage renal disease (esrd). |
2005-12-21 |
2023-01-24 |
Not clear |
| Irfan Qureshi, Hongjiang Chen, Aliza T Brown, Ryan Fitzgerald, Xingjian Zhang, Julie Breckenridge, Rafi Kazi, Amy J Crocker, Markus C St\\xc3\\xbchlinger, Kenneth Lin, John P Cooke, John F Eidt, Mohammed M Mours. Homocysteine-induced vascular dysregulation is mediated by the NMDA receptor. Vascular medicine (London, England) vol 10 issue 3 2005 16235775 |
homocysteine reduced the vascular elaboration of nitric oxide and increased the elaboration of the nitric oxide synthase inhibitor, asymmetric dimethylarginine. |
2005-12-13 |
2023-01-24 |
rat |
| S R Lent. Mechanisms of homocysteine-induced atherothrombosis. Journal of thrombosis and haemostasis : JTH vol 3 issue 8 2005 16102030 |
impairment of endothelial function may be mediated by either accelerated oxidative inactivation of nitric oxide or inhibition of nitric oxide production caused by the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine. |
2005-12-07 |
2023-01-24 |
mouse |
| I E M Bultink, T Teerlink, J A Heijst, B A C Dijkmans, A E Voskuy. Raised plasma levels of asymmetric dimethylarginine are associated with cardiovascular events, disease activity, and organ damage in patients with systemic lupus erythematosus. Annals of the rheumatic diseases vol 64 issue 9 2005 16100343 |
asymmetric dimethylarginine (adma) is an endogenous nitric oxide inhibitor and a new independent risk factor for endothelial dysfunction and cardiovascular disease. |
2005-10-06 |
2023-01-24 |
Not clear |
| Katina M Wilson, Steven R Lent. Mechanisms of the atherogenic effects of elevated homocysteine in experimental models. Seminars in vascular medicine vol 5 issue 2 2005 16047268 |
mechanisms of endothelial dysfunction may include inhibition of endothelial nitric oxide synthase by its endogenous inhibitor, asymmetric dimethylarginine, and oxidative inactivation of nitric oxide mediated by upregulation of prooxidant enzymes and downregulation of antioxidant enzymes. |
2005-09-29 |
2023-01-24 |
mouse |
| Tom Teerlin. Determination of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine in biological samples by HPLC. Methods in molecular medicine vol 108 issue 2005 16028689 |
asymmetric dimethylarginine (adma) is an endogenous inhibitor of all isoforms of nitric oxide synthase, the enzyme that synthesizes nitric oxide from arginine. |
2005-09-16 |
2023-01-24 |
Not clear |
| Danilo Fliser, Kathrin-Kristin Wagner, Astrid Loos, Dimitrios Tsikas, Hermann Halle. Chronic angiotensin II receptor blockade reduces (intra)renal vascular resistance in patients with type 2 diabetes. Journal of the American Society of Nephrology : JASN vol 16 issue 4 2005 15716329 |
nitric oxide metabolism (plasma nitrate and nitrite) and asymmetric dimethylarginine blood levels were not affected by olmesartan and placebo therapy. |
2005-09-13 |
2023-01-24 |
Not clear |
| Yumiko Ohike, Koichi Kozaki, Katsuya Iijima, Masato Eto, Taro Kojima, Eijiro Ohga, Tomofumi Santa, Kazuhiro Imai, Masayoshi Hashimoto, Masao Yoshizumi, Yasuyoshi Ouch. Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine. Circulation journal : official journal of the Japanese Circulation Society vol 69 issue 2 2005 15671617 |
amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure--possible involvement of nitric oxide and asymmetric ng, ng-dimethylarginine. |
2005-08-29 |
2023-01-24 |
Not clear |
| Michiel P C Siroen, Paul A M van Leeuwen, Robert J Nijveldt, Tom Teerlink, Pieter J Wouters, Greet Van den Bergh. Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: a possible explanation of reduced morbidity and mortality? Critical care medicine vol 33 issue 3 2005 15753739 |
asymmetric dimethylarginine, which inhibits production of nitric oxide, has been shown to be a strong and independent predictor of mortality in critically ill patients with clinical evidence of organ dysfunction. |
2005-04-08 |
2023-01-24 |
Not clear |
| Osamu Suda, Masato Tsutsui, Tsuyoshi Morishita, Hiromi Tasaki, Susumu Ueno, Sei Nakata, Takashi Tsujimoto, Yumiko Toyohira, Yoshiaki Hayashida, Yasuyuki Sasaguri, Yoichi Ueta, Yasuhide Nakashima, Nobuyuki Yanagihar. Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress. Arteriosclerosis, thrombosis, and vascular biology vol 24 issue 9 2005 15217805 |
asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress. |
2005-04-05 |
2023-01-24 |
mouse |
| Fortunato Scalera, J\\xc3\\xbcrgen Borlak, Bibiana Beckmann, Jens Martens-Lobenhoffer, Thomas Thum, Michael T\\xc3\\xa4ger, Stefanie M Bode-B\\xc3\\xb6ge. Endogenous nitric oxide synthesis inhibitor asymmetric dimethyl L-arginine accelerates endothelial cell senescence. Arteriosclerosis, thrombosis, and vascular biology vol 24 issue 10 2005 15308550 |
endogenous nitric oxide synthesis inhibitor asymmetric dimethyl l-arginine accelerates endothelial cell senescence. |
2005-03-24 |
2023-01-24 |
Not clear |