| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michiel P C Siroen, Joost R M van der Sijp, Tom Teerlink, Cors van Schaik, Robert J Nijveldt, Paul A M van Leeuwe. The human liver clears both asymmetric and symmetric dimethylarginine. Hepatology (Baltimore, Md.) vol 41 issue 3 2005 15726655 |
asymmetric (adma) and symmetric dimethylarginine (sdma) inhibit production of nitric oxide. |
2005-03-17 |
2023-01-24 |
human |
| Paloma Lluch, Bel\\xc3\\xa9n Torondel, Pascual Medina, Gloria Segarra, Juan A Del Olmo, Miguel A Serra, Jos\\xc3\\xa9 M Rodrig. Plasma concentrations of nitric oxide and asymmetric dimethylarginine in human alcoholic cirrhosis. Journal of hepatology vol 41 issue 1 2005 15246208 |
plasma concentrations of nitric oxide and asymmetric dimethylarginine in human alcoholic cirrhosis. |
2005-01-31 |
2023-01-24 |
human |
| Joseph Loscalz. L-arginine and atherothrombosis. The Journal of nutrition vol 134 issue 10 Suppl 2004 15465788 |
the mechanisms by which l-arginine improves endothelial nitric oxide bioactivity include increased intracellular uptake via the high-affinity cationic transporter; substrate competition with asymmetric dimethylarginine, a naturally occurring inhibitor of nitric oxide synthase; direct antioxidant activity; stimulated release of histamine from mast cells, which produces a vasodilator response; decreased activity of norepinephrine, which promotes the effect of endogenous vasodilators including nitric oxide; and increased insulin secretion, which causes vasodilation. |
2004-11-23 |
2023-01-24 |
Not clear |
| Patrick Vallance, James Leipe. Cardiovascular biology of the asymmetric dimethylarginine:dimethylarginine dimethylaminohydrolase pathway. Arteriosclerosis, thrombosis, and vascular biology vol 24 issue 6 2004 15105281 |
an increasing number of reports indicate that endogenously produced inhibitors of nitric oxide synthase, particularly asymmetric dimethylarginine (adma), regulate nitric oxide generation in disease states. |
2004-11-08 |
2023-01-24 |
Not clear |
| Michael L Selle. Increased (E)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression. Journal of affective disorders vol 80 issue 2-3 2004 15207938 |
increased (e)-4-hydroxy-2-nonenal and asymmetric dimethylarginine concentrations and decreased nitric oxide concentrations in the plasma of patients with major depression. |
2004-09-23 |
2023-01-24 |
Not clear |
| Francesca Mallamaci, Giovanni Tripepi, Renke Maas, Lorenzo Malatino, Rainer B\\xc3\\xb6ger, Carmine Zoccal. Analysis of the relationship between norepinephrine and asymmetric dimethyl arginine levels among patients with end-stage renal disease. Journal of the American Society of Nephrology : JASN vol 15 issue 2 2004 14747391 |
high sympathetic activity and alterations in nitric oxide synthesis attributable to accumulation of the endogenous nitric oxide synthase inhibitor asymmetric dimethylarginine (adma) have recently been identified as potential causal mechanisms for the high cardiovascular mortality rates among patients with esrd. |
2004-09-20 |
2023-01-24 |
Not clear |
| Dierk H Endemann, Ernesto L Schiffri. Endothelial dysfunction. Journal of the American Society of Nephrology : JASN vol 15 issue 8 2004 15284284 |
vasoactive peptides such as angiotensin ii and endothelin-1; the accumulation of asymmetric dimethylarginine, an endogenous nitric oxide inhibitor; hypercholesterolemia; hyperhomocysteinemia; altered insulin signaling; and hyperglycemia can contribute to these different mechanisms. |
2004-09-20 |
2023-01-24 |
Not clear |
| Jun-lin Jiang, De-jian Jiang, Yu-hai Tang, Nian-sheng Li, Han-wu Deng, Yuan-jian L. Effect of simvastatin on endothelium-dependent vaso-relaxation and endogenous nitric oxide synthase inhibitor. Acta pharmacologica Sinica vol 25 issue 7 2004 15210062 |
to investigate the effect of simvastatin on endothelium-dependent vasorelaxation and endogenous nitric oxide synthesis inhibitor asymmetric dimethylarginine (adma) in rats and cultured ecv304 cells. |
2004-08-31 |
2023-01-24 |
rat |
| Cam T L Tran, James M Leiper, Patrick Vallanc. The DDAH/ADMA/NOS pathway. Atherosclerosis. Supplements vol 4 issue 4 2004 14664901 |
an increasing number of reports in the literature indicate that endogenously produced inhibitors of nitric oxide synthase (nos), particularly asymmetric dimethylarginine (adma) regulate nitric oxide generation in numerous disease states. |
2004-04-23 |
2023-01-24 |
Not clear |
| Steven R Lentz, Roman N Rodionov, Sanjana Daya. Hyperhomocysteinemia, endothelial dysfunction, and cardiovascular risk: the potential role of ADMA. Atherosclerosis. Supplements vol 4 issue 4 2004 14664904 |
one potential mechanism for decreased nitric oxide bioavailability is inhibition of endothelial nitric oxide synthase by its endogenous inhibitor, asymmetric dimethylarginine (adma). |
2004-04-23 |
2023-01-24 |
Not clear |
| Masayuki Saitoh, Tomohiro Osanai, Takaatsu Kamada, Toshiro Matsunaga, Hiroshi Ishizaka, Hiroyuki Hanada, Ken Okumur. High plasma level of asymmetric dimethylarginine in patients with acutely exacerbated congestive heart failure: role in reduction of plasma nitric oxide level. Heart and vessels vol 18 issue 4 2004 14520484 |
high plasma level of asymmetric dimethylarginine in patients with acutely exacerbated congestive heart failure: role in reduction of plasma nitric oxide level. |
2004-02-11 |
2023-01-24 |
human |
| M L Selle. Increased concentrations of homocysteine and asymmetric dimethylarginine and decreased concentrations of nitric oxide in the plasma of patients with Alzheimer's disease. Neurobiology of aging vol 24 issue 7 2003 12928048 |
increased concentrations of homocysteine and asymmetric dimethylarginine and decreased concentrations of nitric oxide in the plasma of patients with alzheimer's disease. |
2003-12-09 |
2023-01-24 |
human |
| Tomohiro Osanai, Naoto Fujiwara, Masayuki Saitoh, Satoko Sasaki, Hirofumi Tomita, Masayuki Nakamura, Hiroshi Osawa, Hideaki Yamabe, Ken Okumur. Relationship between salt intake, nitric oxide and asymmetric dimethylarginine and its relevance to patients with end-stage renal disease. Blood purification vol 20 issue 5 2003 12207094 |
relationship between salt intake, nitric oxide and asymmetric dimethylarginine and its relevance to patients with end-stage renal disease. |
2003-07-17 |
2023-01-24 |
Not clear |
| Seiji Ueda, Seiya Kato, Hidehiro Matsuoka, Masumi Kimoto, Seiya Okuda, Minoru Morimatsu, Tsutomu Imaizum. Regulation of cytokine-induced nitric oxide synthesis by asymmetric dimethylarginine: role of dimethylarginine dimethylaminohydrolase. Circulation research vol 92 issue 2 2003 12574151 |
regulation of cytokine-induced nitric oxide synthesis by asymmetric dimethylarginine: role of dimethylarginine dimethylaminohydrolase. |
2003-02-14 |
2023-01-24 |
rat |
| PierMarco Piatti, Gabriele Fragasso, Lucilla D Monti, Emanuela Setola, Pietro Lucotti, Isabella Fermo, Rita Paroni, Elena Galluccio, Guido Pozza, Sergio Chierchia, Alberto Margonat. Acute intravenous L-arginine infusion decreases endothelin-1 levels and improves endothelial function in patients with angina pectoris and normal coronary arteriograms: correlation with asymmetric dimethylarginine levels. Circulation vol 107 issue 3 2003 12551867 |
we tested the hypothesis that asymmetric dimethylarginine (adma) levels could be elevated and influence endothelin-1 and nitric oxide release and action in patients with cardiac syndrome x (csx). |
2003-02-05 |
2023-01-24 |
human |
| Torbj\\xc3\\xb8rn Holm, P\\xc3\\xa5l Aukrust, Erik Aagaard, Thor Ueland, Tor S Haugstad, John Kjekshus, Svein Simonsen, Stig S Fr\\xc3\\xb8land, Lars Gullestad, Arne K Andreasse. Hypertension in relation to nitric oxide, asymmetric dimethylarginine, and inflammation: different patterns in heart transplant recipients and individuals with essential hypertension. Transplantation vol 74 issue 10 2002 12451238 |
hypertension in relation to nitric oxide, asymmetric dimethylarginine, and inflammation: different patterns in heart transplant recipients and individuals with essential hypertension. |
2002-12-12 |
2023-01-24 |
Not clear |
| Jaw-Wen Chen, Nai-Wei Hsu, Tao-Cheng Wu, Shing-Jong Lin, Mau-Song Chan. Long-term angiotensin-converting enzyme inhibition reduces plasma asymmetric dimethylarginine and improves endothelial nitric oxide bioavailability and coronary microvascular function in patients with syndrome X. The American journal of cardiology vol 90 issue 9 2002 12398965 |
long-term angiotensin-converting enzyme inhibition reduces plasma asymmetric dimethylarginine and improves endothelial nitric oxide bioavailability and coronary microvascular function in patients with syndrome x. angiotensin-converting enzyme (ace) inhibition has been shown to improve clinical myocardial ischemia in patients with syndrome x (angina pectoris, positive treadmill exercise test, normal coronary angiograms, and no evidence of coronary spasm). |
2002-12-09 |
2023-01-24 |
human |
| V Kostourou, S P Robinson, J E Cartwright, G St J Whitle. Dimethylarginine dimethylaminohydrolase I enhances tumour growth and angiogenesis. British journal of cancer vol 87 issue 6 2002 12237779 |
asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthesis. |
2002-10-24 |
2023-01-24 |
rat |
| Tom Teerlink, Robert J Nijveldt, Sigrid de Jong, Paul A M van Leeuwe. Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography. Analytical biochemistry vol 303 issue 2 2002 11950212 |
asymmetric dimethylarginine (adma), an endogenous inhibitor of nitric oxide synthase (nos), may be related to reduced biosynthesis of nitric oxide in diseases associated with accelerated atherosclerosis. |
2002-06-04 |
2023-01-24 |
human |
| Masashi Beppu, Satoshi Obayashi, Takeshi Aso, Moritaka Goto, Hiroshi Azum. Endogenous nitric oxide synthase inhibitors in endothelial cells, endothelin-1 within the vessel wall, and intimal hyperplasia in perimenopausal human uterine arteries. Journal of cardiovascular pharmacology vol 39 issue 2 2002 11791004 |
the present experiments were designed to investigate the ability to produce nitric oxide, concentrations of n(g)-monomethyl-l-arginine (l-nmma), and asymmetric n(g), n(g)-dimethyl-l-arginine (adma) in endothelial cells, endothelin-1 within the vessel wall, and the degree of intimal hyperplasia (intima/media ratio) in perimenopausal human uterine arteries. |
2002-04-29 |
2023-01-24 |
human |