| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kutibh Chihabi, Anthony D Morielli, John T Gree. Intracerebellar infusion of the protein kinase M zeta (PKMζ) inhibitor zeta-inhibitory peptide (ZIP) disrupts eyeblink classical conditioning. Behavioral neuroscience. vol 130. issue 6. 2017-11-16. PMID:26949968. |
delay eyeblink conditioning (ebc) is an established model for the assessment of cerebellar learning; here, we show that pkc-ζ and pkm-ζ are highly expressed in the cerebellar cortex, with highest expression found in purkinje cell (pc) nuclei. |
2017-11-16 |
2023-08-13 |
rat |
| Bruno Benedetti, Ariane Benedetti, Bernhard E Fluche. Loss of the calcium channel β4 subunit impairs parallel fibre volley and Purkinje cell firing in cerebellum of adult ataxic mice. The European journal of neuroscience. vol 43. issue 11. 2017-11-13. PMID:27003325. |
loss of the calcium channel β4 subunit impairs parallel fibre volley and purkinje cell firing in cerebellum of adult ataxic mice. |
2017-11-13 |
2023-08-13 |
mouse |
| Bruno Benedetti, Ariane Benedetti, Bernhard E Fluche. Loss of the calcium channel β4 subunit impairs parallel fibre volley and Purkinje cell firing in cerebellum of adult ataxic mice. The European journal of neuroscience. vol 43. issue 11. 2017-11-13. PMID:27003325. |
we therefore studied the structure and function of purkinje cells in acute cerebellar slices of the β4 (-/-) ataxic (lethargic) mouse, finding that loss of β4 affected purkinje cell input, morphology and pacemaker activity. |
2017-11-13 |
2023-08-13 |
mouse |
| Paola Caporali, Francesco Bruno, Giampiero Palladino, Jessica Dragotto, Laura Petrosini, Franco Mangia, Robert P Erickson, Sonia Canterini, Maria Teresa Fiorenz. Developmental delay in motor skill acquisition in Niemann-Pick C1 mice reveals abnormal cerebellar morphogenesis. Acta neuropathologica communications. vol 4. issue 1. 2017-10-24. PMID:27586038. |
purkinje cell (pc) degeneration is the main sign of cerebellar dysfunction in both npc1 patients and animal models. |
2017-10-24 |
2023-08-13 |
mouse |
| Francesca Gelfo, Fulvio Florenzano, Francesca Foti, Lorena Burello, Laura Petrosini, Paola De Bartol. Lesion-induced and activity-dependent structural plasticity of Purkinje cell dendritic spines in cerebellar vermis and hemisphere. Brain structure & function. vol 221. issue 7. 2017-09-29. PMID:26420278. |
lesion-induced and activity-dependent structural plasticity of purkinje cell dendritic spines in cerebellar vermis and hemisphere. |
2017-09-29 |
2023-08-13 |
rat |
| Francesca Gelfo, Fulvio Florenzano, Francesca Foti, Lorena Burello, Laura Petrosini, Paola De Bartol. Lesion-induced and activity-dependent structural plasticity of Purkinje cell dendritic spines in cerebellar vermis and hemisphere. Brain structure & function. vol 221. issue 7. 2017-09-29. PMID:26420278. |
this study was aimed to characterize the effects of a hemicerebellectomy (hcb) combined or not with the exposition to environmental enrichment (ee) on dendritic spine density and size in purkinje cell proximal and distal compartments of cerebellar vermian and hemispherical regions. |
2017-09-29 |
2023-08-13 |
rat |
| Akira Iizuka, Yasunori Matsuzaki, Ayumu Konno, Hirokazu Hira. Plasticity of the developmentally arrested staggerer cerebellum in response to exogenous RORα. Brain structure & function. vol 221. issue 6. 2017-09-28. PMID:26122696. |
an rorα-deficient cerebellum has a persistent external granular layer (egl), rudimentary purkinje cell (pc) dendrites, grossly reduced numbers of immature parallel fiber (pf)-pc synapses, and multiple climbing fibers (cf) innervating pcs in mice after 3 weeks of age when these features have disappeared in wild-type mice. |
2017-09-28 |
2023-08-13 |
mouse |
| James Cairns, Doug Swanson, Joanna Yeung, Anna Sinova, Ronny Chan, Praneetha Potluri, Price Dickson, Guy Mittleman, Dan Goldowit. Abnormalities in the Structure and Function of Cerebellar Neurons and Neuroglia in the Lc/+ Chimeric Mouse Model of Variable Developmental Purkinje Cell Loss. Cerebellum (London, England). vol 16. issue 1. 2017-09-26. PMID:26837618. |
abnormalities in the structure and function of cerebellar neurons and neuroglia in the lc/+ chimeric mouse model of variable developmental purkinje cell loss. |
2017-09-26 |
2023-08-13 |
mouse |
| Ronit Givon-Mayo, Shlomi Haar, Yoav Aminov, Esther Simons, Opher Donchi. Long Pauses in Cerebellar Interneurons in Anesthetized Animals. Cerebellum (London, England). vol 16. issue 2. 2017-09-22. PMID:27255704. |
are long pauses in the firing of cerebellar interneurons (cins) related to purkinje cell (pc) pauses? |
2017-09-22 |
2023-08-13 |
Not clear |
| Frédéric Doussau, Jean-Luc Dupont, Dorine Neel, Aline Schneider, Bernard Poulain, Jean Louis Boss. Organotypic cultures of cerebellar slices as a model to investigate demyelinating disorders. Expert opinion on drug discovery. vol 12. issue 10. 2017-09-22. PMID:28712329. |
however, in the cerebellum, neurological disability in multiple sclerosis also results from channelopathies which induce changes in purkinje cell excitability. |
2017-09-22 |
2023-08-13 |
Not clear |
| Jurairat Khongrum, Jintanaporn Wattanathor. Laser Acupuncture at HT7 Improves the Cerebellar Disorders in Valproic Acid-Rat Model of Autism. Journal of acupuncture and meridian studies. vol 10. issue 4. 2017-09-21. PMID:28889839. |
at the end of study, the changes of oxidative stress markers, the expressions of cytokines interleukin 6 (il-6) and glutamic acid decarboxylase (gad) proteins (65 kda and 67 kda) together with gamma-aminobutyric acid transaminase (gaba-t) activity and density of purkinje cell in the cerebellum were assessed. |
2017-09-21 |
2023-08-13 |
rat |
| Nishant P Visavadiya, Joe E Springe. Altered Cerebellar Circuitry following Thoracic Spinal Cord Injury in Adult Rats. Neural plasticity. vol 2016. 2017-09-20. PMID:27504204. |
we provide evidence of sci-induced cerebellar synaptic changes involving a loss of granule cell parallel fiber input to distal regions of the purkinje cell dendritic tree. |
2017-09-20 |
2023-08-13 |
mouse |
| Clara A Amegandjin, Wafaa Jammow, Sylvie Laforest, Mustapha Riad, Moogeh Baharnoori, Frédérique Badeaux, Luc DesGroseillers, Keith K Murai, Elena B Pasquale, Guy Drolet, Guy Douce. Regional expression and ultrastructural localization of EphA7 in the hippocampus and cerebellum of adult rat. The Journal of comparative neurology. vol 524. issue 12. 2017-09-13. PMID:26780036. |
moderate levels were detected in habenula, striatum, amygdala, the cingulate, piriform and entorhinal cortex, and in cerebellum, notably the purkinje cell layer. |
2017-09-13 |
2023-08-13 |
mouse |
| Clara A Amegandjin, Wafaa Jammow, Sylvie Laforest, Mustapha Riad, Moogeh Baharnoori, Frédérique Badeaux, Luc DesGroseillers, Keith K Murai, Elena B Pasquale, Guy Drolet, Guy Douce. Regional expression and ultrastructural localization of EphA7 in the hippocampus and cerebellum of adult rat. The Journal of comparative neurology. vol 524. issue 12. 2017-09-13. PMID:26780036. |
in contrast, in the cerebellum, the purkinje cell bodies were the most strongly immunolabeled elements. |
2017-09-13 |
2023-08-13 |
mouse |
| G J Stephen. Does modulation of the endocannabinoid system have potential therapeutic utility in cerebellar ataxia? The Journal of physiology. vol 594. issue 16. 2017-08-29. PMID:26970080. |
cerebellar ataxias represent a spectrum of disorders which are, however, linked by common symptoms of motor incoordination and typically associated with deficiency in purkinje cell firing activity and, often, degeneration. |
2017-08-29 |
2023-08-13 |
mouse |
| Teresa García-Lezana, Marc Oria, Jordi Romero-Giménez, Jordi Bové, Miquel Vila, Joan Genescà, Laia Chavarria, Juan Cordob. Cerebellar neurodegeneration in a new rat model of episodic hepatic encephalopathy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 37. issue 3. 2017-08-18. PMID:27154504. |
in cerebellum, stereology showed a reduction in purkinje cell population in portacaval anastomosis and pca+nh |
2017-08-18 |
2023-08-13 |
rat |
| Michael A Gaffield, Jason M Christi. Movement Rate Is Encoded and Influenced by Widespread, Coherent Activity of Cerebellar Molecular Layer Interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 18. 2017-08-18. PMID:28389475. |
inhibition from molecular layer interneurons (mlis) is thought to play an important role in cerebellar function by sharpening the precision of purkinje cell spike output. |
2017-08-18 |
2023-08-13 |
Not clear |
| Samira Abbasi, Amber E Hudson, Selva K Maran, Ying Cao, Ataollah Abbasi, Detlef H Heck, Dieter Jaege. Robust transmission of rate coding in the inhibitory Purkinje cell to cerebellar nuclei pathway in awake mice. PLoS computational biology. vol 13. issue 6. 2017-08-18. PMID:28617798. |
we analyze the transmission properties of the purkinje cell (pc) to cerebellar nucleus (cn) pathway in a modeling study using a data set recorded in awake mice containing respiratory rate modulation. |
2017-08-18 |
2023-08-13 |
mouse |
| Emmet M Power, Adrienne Morales, Ruth M Empso. Prolonged Type 1 Metabotropic Glutamate Receptor Dependent Synaptic Signaling Contributes to Spino-Cerebellar Ataxia Type 1. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 18. 2017-08-14. PMID:27147646. |
type 1 metabotropic glutamate receptor (mglur1)-dependent signaling at parallel fiber to purkinje neuron synapses is critical for cerebellar function. |
2017-08-14 |
2023-08-13 |
mouse |
| Milos Stanojlovic, Xiaosha Pang, Yifeng Lin, Sarrabeth Stone, Marija Cvetanovic, Wensheng Li. Inhibition of Vascular Endothelial Growth Factor Receptor 2 Exacerbates Loss of Lower Motor Neurons and Axons during Experimental Autoimmune Encephalomyelitis. PloS one. vol 11. issue 7. 2017-08-02. PMID:27466819. |
interestingly, we found that treatment with su5416, a selective vegfr2 inhibitor, starting after the onset of eae clinical symptoms exacerbated lower motor neuron loss and axon loss in the lumbar spinal cord of mice undergoing eae, but did not alter purkinje neuron loss in the cerebellum or upper motor neuron loss in the cerebral cortex. |
2017-08-02 |
2023-08-13 |
mouse |